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The map label for this gene is nadA [H]

Identifier: 119774848

GI number: 119774848

Start: 2092642

End: 2093709

Strand: Direct

Name: nadA [H]

Synonym: Sama_1712

Alternate gene names: 119774848

Gene position: 2092642-2093709 (Clockwise)

Preceding gene: 119774847

Following gene: 119774849

Centisome position: 48.6

GC content: 54.4

Gene sequence:

>1068_bases
ATGAGTCAGCAAGCCCCCATTCTGGAACCTATTCAGTATCCATTTCCTGCCAAGCCTATTCCGCTGTCGGATGTGCAAAA
GCTGGAATACAAAGAAAAAATCAAGGCGCTTCTAAAAGCTCGGGACGCCGTGCTGGTTGCCCATTACTACACAGATCCTG
AAATTCAGGCGCTGGCCGAAGAAACCGGCGGCTGTGTATCTGATTCGCTGGAAATGGCCCGCTTTGGTCGCGATCACCCC
GCCAAGACGCTTATCGTCGCCGGTGTGAAATTCATGGGTGAAACCGCCAAAATCTTAAGCCCGGAAAAAACCGTGCTGAT
GCCAACGCTGGAAGCCACCTGTTCGTTGGATGTGGGTTGCCCCATCGAGACCTTCAGCGCCTTTTGCGATGCTCACCCAG
ACCACACTGTAGTGGTGTACGCCAACACCTCTGCGGCGGTAAAGGCCCGTGCTGATTGGGTAGTCACTTCCAGCATTGCC
CTCGAAATCGTTGAGCACCTGGACAGCGAAGGCAAGAAAATCATCTGGGGACCGGACAGACACCTTGGCAGCTACATCGC
CAAACAAACCGGTGCAGAGATGCTGCTGTGGCAGGGCGAGTGTATCGTTCATGATGAATTCAAAGCCAAGGCATTGCGGG
AGCTTAAACTACAGTATCCCGATGCCGCTGTGCTGGTGCATCCAGAATCCCCCGCCAGCGTGGTGGAAATGGCCGATGCC
GTAGGCTCGACCAGCCAGCTTATCAAGGCCGCGCAAACCTTGCCAAACGAGACCTTTATCGTGGCCACTGATAAGGGCAT
CTTCTATAAGATGCAGCAGGCGGCTCCGGGCAAGACATTGATTGAAGCTCCAACCGGTGGCAACGGCGCCACCTGTAAGA
GTTGTGCCCATTGCCCCTGGATGGCCATGAATGGCCTGAAAGCCATTGAAGCAGCGCTCAGTGCTGACGATGCCAGTAGA
CATGAGATTTTCGTTGATGACGCACTGCGCGAAAGAGCAAAACTGCCGCTGGATCGTATGCTGGACTTTGCCAAAACCCT
CAATATGCAGGTGAAGGGCAACGCCTGA

Upstream 100 bases:

>100_bases
GCTTGATTCGGCCGTACTCGACGCCCCCGGGCGAAAACACCTTAATCTTTTGGTCGGGTTTTCGTATAATGCGCCAAAGT
TGTGTGATGTTGGAATTACC

Downstream 100 bases:

>100_bases
TAGTCACAGTGCCAGGCTGAAACATGATCCACTCCACAAAAACCGCTTCGGCGGTTTTTTTACAGCCAATCCAAGACCAA
TTAGGTATATGCCAACTACA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSQQAPILEPIQYPFPAKPIPLSDVQKLEYKEKIKALLKARDAVLVAHYYTDPEIQALAEETGGCVSDSLEMARFGRDHP
AKTLIVAGVKFMGETAKILSPEKTVLMPTLEATCSLDVGCPIETFSAFCDAHPDHTVVVYANTSAAVKARADWVVTSSIA
LEIVEHLDSEGKKIIWGPDRHLGSYIAKQTGAEMLLWQGECIVHDEFKAKALRELKLQYPDAAVLVHPESPASVVEMADA
VGSTSQLIKAAQTLPNETFIVATDKGIFYKMQQAAPGKTLIEAPTGGNGATCKSCAHCPWMAMNGLKAIEAALSADDASR
HEIFVDDALRERAKLPLDRMLDFAKTLNMQVKGNA

Sequences:

>Translated_355_residues
MSQQAPILEPIQYPFPAKPIPLSDVQKLEYKEKIKALLKARDAVLVAHYYTDPEIQALAEETGGCVSDSLEMARFGRDHP
AKTLIVAGVKFMGETAKILSPEKTVLMPTLEATCSLDVGCPIETFSAFCDAHPDHTVVVYANTSAAVKARADWVVTSSIA
LEIVEHLDSEGKKIIWGPDRHLGSYIAKQTGAEMLLWQGECIVHDEFKAKALRELKLQYPDAAVLVHPESPASVVEMADA
VGSTSQLIKAAQTLPNETFIVATDKGIFYKMQQAAPGKTLIEAPTGGNGATCKSCAHCPWMAMNGLKAIEAALSADDASR
HEIFVDDALRERAKLPLDRMLDFAKTLNMQVKGNA
>Mature_354_residues
SQQAPILEPIQYPFPAKPIPLSDVQKLEYKEKIKALLKARDAVLVAHYYTDPEIQALAEETGGCVSDSLEMARFGRDHPA
KTLIVAGVKFMGETAKILSPEKTVLMPTLEATCSLDVGCPIETFSAFCDAHPDHTVVVYANTSAAVKARADWVVTSSIAL
EIVEHLDSEGKKIIWGPDRHLGSYIAKQTGAEMLLWQGECIVHDEFKAKALRELKLQYPDAAVLVHPESPASVVEMADAV
GSTSQLIKAAQTLPNETFIVATDKGIFYKMQQAAPGKTLIEAPTGGNGATCKSCAHCPWMAMNGLKAIEAALSADDASRH
EIFVDDALRERAKLPLDRMLDFAKTLNMQVKGNA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=336, Percent_Identity=74.1071428571429, Blast_Score=534, Evalue=1e-153,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38545; Mature: 38414

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQAPILEPIQYPFPAKPIPLSDVQKLEYKEKIKALLKARDAVLVAHYYTDPEIQALAE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHHH
ETGGCVSDSLEMARFGRDHPAKTLIVAGVKFMGETAKILSPEKTVLMPTLEATCSLDVGC
HHCCCHHHHHHHHHCCCCCCCCEEEEHHHHHHCCHHHHCCCCCEEEEEECHHHEEECCCC
PIETFSAFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDSEGKKIIWGPDR
CHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHCCCCCEEEECCCH
HLGSYIAKQTGAEMLLWQGECIVHDEFKAKALRELKLQYPDAAVLVHPESPASVVEMADA
HHHHHHHHHCCCCEEEECCCEEEECHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHH
VGSTSQLIKAAQTLPNETFIVATDKGIFYKMQQAAPGKTLIEAPTGGNGATCKSCAHCPW
CCCHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCCEEEECCCCCCCCCCHHHCCCCH
MAMNGLKAIEAALSADDASRHEIFVDDALRERAKLPLDRMLDFAKTLNMQVKGNA
HHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHCCCHHHHHHHHHHCCEEEECCC
>Mature Secondary Structure 
SQQAPILEPIQYPFPAKPIPLSDVQKLEYKEKIKALLKARDAVLVAHYYTDPEIQALAE
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHHH
ETGGCVSDSLEMARFGRDHPAKTLIVAGVKFMGETAKILSPEKTVLMPTLEATCSLDVGC
HHCCCHHHHHHHHHCCCCCCCCEEEEHHHHHHCCHHHHCCCCCEEEEEECHHHEEECCCC
PIETFSAFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDSEGKKIIWGPDR
CHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHCCCCCEEEECCCH
HLGSYIAKQTGAEMLLWQGECIVHDEFKAKALRELKLQYPDAAVLVHPESPASVVEMADA
HHHHHHHHHCCCCEEEECCCEEEECHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHH
VGSTSQLIKAAQTLPNETFIVATDKGIFYKMQQAAPGKTLIEAPTGGNGATCKSCAHCPW
CCCHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCCEEEECCCCCCCCCCHHHCCCCH
MAMNGLKAIEAALSADDASRHEIFVDDALRERAKLPLDRMLDFAKTLNMQVKGNA
HHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHCCCHHHHHHHHHHCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]