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The map label for this gene is hlyB [H]

Identifier: 119774849

GI number: 119774849

Start: 2093877

End: 2095877

Strand: Direct

Name: hlyB [H]

Synonym: Sama_1713

Alternate gene names: 119774849

Gene position: 2093877-2095877 (Clockwise)

Preceding gene: 119774848

Following gene: 119774850

Centisome position: 48.63

GC content: 51.07

Gene sequence:

>2001_bases
ATGAACATGCGATGGATTGCCAACCTCAGTATGAAACTCAAACTTATGCTGGTATTCATGCCACCTCTGTTGGGCTTTCT
CATCTTTGGCGGCATTTTGCTGGACGACAAAATAGATGAGTCAAACTCTCTCCAAAATGTACAGCAATTAACAGAACTTG
CTGTCATCAACAGCGCTCTGGTGCATGAGCTGCAAAAAGAGCGCGGCATGAGCGCAGGCTTTTTGGGCTCCAAGGGCCAG
AGTTTTAAGGCTCAGTTGCCTTCACAACGTAGTTTGACCGATGAGAAATTGCGCACTTTCACCCAATACGTGAAGGGAAA
GCAGTTCGCCAGCCATGTGCAGGATGAGGTGCAGGGGGCGGCAGCTGAACTGAGCAGACTGGCAAGCATGCGTGGTCAGG
TGGATGGCCTGAGCATTTCAGTGGCAGACGAAGTCGCCTATTACACAGGCCTTAATAAGCGCCTGCTCGGTATAGTCGAT
GACATAGTTCATGAAGGCGCAGATAAGAAAATCGCCGTGGCGTCTGCTGCCTTCAGTGCTTATCTGCAAATGAAAGAGCG
TGCCGGGATAGAAAGAGCAGTGCTTTCCTCTACTTTTGGCAACGACGGTTTCAAACCCGGAGTGTATACCCGAGCCGTGA
GATTGATGTCAGAACAGGATACCTACGCAGAGCGTTTCGATGCGCTCGCTTCAGACGAGTGGCGCCGCGAATGGCAACGG
ACGTTGCAGAGTCCTGAAATTGCCGAAGTGAGCCGTTATCGAGAACTGGCTTTAAGTCAGGACAATCAAGCCATCGCCAA
AACCTCTCCCGAAGATTGGTTTAAGGCATCAACTGGGCGGATTAACTTGCTCTACAGTGTTGAAAATGTGCTGGCAAAGA
GTCTTGATGAACTCACCGATGCCCGTCTTCAGACTGCCAATTGGCATATGATGCTGATGATGTCTGCGCTTGCGGTTGTT
TTGTTCCTCGTGGCGATGATGGGGCTATCGGTCATGGGGTATCTCAATCGCTCCGTGGTCCATATAGAAAATCAGATGCG
TCGAGCCCGTGAAGAGTTCGATTTATCGACCCGAATCACGCTGGACAGCACCGACGAATTGGGGAGCCTTGGCAATGCTT
TTAACGGCATGATGAATGATTTTGAGGCCGTTATACACCAGGTTAAAACCAACAGTCTGAAAGTAACAGATGCGGTTAAA
CGCATGGAATCCCACTCCAATCAGATGCGCCATGATGTAGCACAGGGCCACTCAGAGGCCGAACAGGTGGCATCCGCCAT
GACTGAAATGAGCGCTACAGTGAGCCAGATTGCATCCAACGCAGTGGAAGCCGCATCCGCATCCGGCAAAGCCAATCAGG
AAGCCCGCACCGGTAATAAAGAAGTCGGTAACACAGGAAAAACAATAAGCGCGCTTGCATCAGAAATCGATGCCGCAGCG
ATTGCCATTACCAAGCTGGATACCGATATTCAGGGTATTGTGAGTGTACTCGAGGTAATAAGCGGCATTGCGGAGCAAAC
CAATTTGCTGGCTCTCAACGCCGCTATTGAGGCGGCAAGGGCAGGGGAAATGGGTCGTGGTTTTGCTGTTGTGGCTGACG
AAGTTCGCTCGCTTGCACAGCGAGCTCAATCGTCCACTACGGATATTCGCACCATGACAGAGCGGCTTAAGGAGGGGGCC
AGGGTTGCGGTGGATGCCATGTCTCGCGGCCAAACTCAGGCTCAGGCCAGTGTCCAGGAAGTCAATCATGCCGGTGAAGA
GCTCAGACGTATTGTGGACTATGTGAGTGTCATTGACAGTATGAACGAGCAGATTGCAGCGGCAACTCACGAGCAAAGTG
CTGTTGCTGAAGAAGTGAATCGCAATGCGCTCAGGATCAGTGAAATCTATCAAAACACCCATCAGGTCGCCGATGAGTTG
GGGCGTATCAATGACGATTTGCTGAGTGCGGTTGATGCCATGGGTAAAGAAGTCAGCAAATTTTCCTTAAGTCGTGGCTG
A

Upstream 100 bases:

>100_bases
AATCCAAGACCAATTAGGTATATGCCAACTACACTTACCCTTTTAGAATCCATAAAGCCCTTGCTACAGGCGCGTCTTTA
TTAGTTTAAAGGGAATCACT

Downstream 100 bases:

>100_bases
TTGGCAATCGCGGGAATTAGAAAAATTTACGCTGCTTAAAATAGGTAAAAACTGCTGGCAAAAAGCGGGTTTGAACCCGC
TTTTTTGTTATTTTGCGTTC

Product: putative methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 666; Mature: 666

Protein sequence:

>666_residues
MNMRWIANLSMKLKLMLVFMPPLLGFLIFGGILLDDKIDESNSLQNVQQLTELAVINSALVHELQKERGMSAGFLGSKGQ
SFKAQLPSQRSLTDEKLRTFTQYVKGKQFASHVQDEVQGAAAELSRLASMRGQVDGLSISVADEVAYYTGLNKRLLGIVD
DIVHEGADKKIAVASAAFSAYLQMKERAGIERAVLSSTFGNDGFKPGVYTRAVRLMSEQDTYAERFDALASDEWRREWQR
TLQSPEIAEVSRYRELALSQDNQAIAKTSPEDWFKASTGRINLLYSVENVLAKSLDELTDARLQTANWHMMLMMSALAVV
LFLVAMMGLSVMGYLNRSVVHIENQMRRAREEFDLSTRITLDSTDELGSLGNAFNGMMNDFEAVIHQVKTNSLKVTDAVK
RMESHSNQMRHDVAQGHSEAEQVASAMTEMSATVSQIASNAVEAASASGKANQEARTGNKEVGNTGKTISALASEIDAAA
IAITKLDTDIQGIVSVLEVISGIAEQTNLLALNAAIEAARAGEMGRGFAVVADEVRSLAQRAQSSTTDIRTMTERLKEGA
RVAVDAMSRGQTQAQASVQEVNHAGEELRRIVDYVSVIDSMNEQIAAATHEQSAVAEEVNRNALRISEIYQNTHQVADEL
GRINDDLLSAVDAMGKEVSKFSLSRG

Sequences:

>Translated_666_residues
MNMRWIANLSMKLKLMLVFMPPLLGFLIFGGILLDDKIDESNSLQNVQQLTELAVINSALVHELQKERGMSAGFLGSKGQ
SFKAQLPSQRSLTDEKLRTFTQYVKGKQFASHVQDEVQGAAAELSRLASMRGQVDGLSISVADEVAYYTGLNKRLLGIVD
DIVHEGADKKIAVASAAFSAYLQMKERAGIERAVLSSTFGNDGFKPGVYTRAVRLMSEQDTYAERFDALASDEWRREWQR
TLQSPEIAEVSRYRELALSQDNQAIAKTSPEDWFKASTGRINLLYSVENVLAKSLDELTDARLQTANWHMMLMMSALAVV
LFLVAMMGLSVMGYLNRSVVHIENQMRRAREEFDLSTRITLDSTDELGSLGNAFNGMMNDFEAVIHQVKTNSLKVTDAVK
RMESHSNQMRHDVAQGHSEAEQVASAMTEMSATVSQIASNAVEAASASGKANQEARTGNKEVGNTGKTISALASEIDAAA
IAITKLDTDIQGIVSVLEVISGIAEQTNLLALNAAIEAARAGEMGRGFAVVADEVRSLAQRAQSSTTDIRTMTERLKEGA
RVAVDAMSRGQTQAQASVQEVNHAGEELRRIVDYVSVIDSMNEQIAAATHEQSAVAEEVNRNALRISEIYQNTHQVADEL
GRINDDLLSAVDAMGKEVSKFSLSRG
>Mature_666_residues
MNMRWIANLSMKLKLMLVFMPPLLGFLIFGGILLDDKIDESNSLQNVQQLTELAVINSALVHELQKERGMSAGFLGSKGQ
SFKAQLPSQRSLTDEKLRTFTQYVKGKQFASHVQDEVQGAAAELSRLASMRGQVDGLSISVADEVAYYTGLNKRLLGIVD
DIVHEGADKKIAVASAAFSAYLQMKERAGIERAVLSSTFGNDGFKPGVYTRAVRLMSEQDTYAERFDALASDEWRREWQR
TLQSPEIAEVSRYRELALSQDNQAIAKTSPEDWFKASTGRINLLYSVENVLAKSLDELTDARLQTANWHMMLMMSALAVV
LFLVAMMGLSVMGYLNRSVVHIENQMRRAREEFDLSTRITLDSTDELGSLGNAFNGMMNDFEAVIHQVKTNSLKVTDAVK
RMESHSNQMRHDVAQGHSEAEQVASAMTEMSATVSQIASNAVEAASASGKANQEARTGNKEVGNTGKTISALASEIDAAA
IAITKLDTDIQGIVSVLEVISGIAEQTNLLALNAAIEAARAGEMGRGFAVVADEVRSLAQRAQSSTTDIRTMTERLKEGA
RVAVDAMSRGQTQAQASVQEVNHAGEELRRIVDYVSVIDSMNEQIAAATHEQSAVAEEVNRNALRISEIYQNTHQVADEL
GRINDDLLSAVDAMGKEVSKFSLSRG

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=340, Percent_Identity=30.5882352941176, Blast_Score=124, Evalue=3e-29,
Organism=Escherichia coli, GI1788195, Length=284, Percent_Identity=33.8028169014084, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI1788194, Length=314, Percent_Identity=27.7070063694268, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1787690, Length=364, Percent_Identity=29.6703296703297, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1789453, Length=345, Percent_Identity=27.8260869565217, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 72828; Mature: 72828

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50885 HAMP ; PS50906 NIT ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCC
>Mature Secondary Structure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HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]