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The map label for this gene is pgm [H]

Identifier: 119774842

GI number: 119774842

Start: 2085048

End: 2086730

Strand: Direct

Name: pgm [H]

Synonym: Sama_1706

Alternate gene names: 119774842

Gene position: 2085048-2086730 (Clockwise)

Preceding gene: 119774841

Following gene: 119774844

Centisome position: 48.42

GC content: 53.54

Gene sequence:

>1683_bases
TTGGCTATCCATGACCGCGCAGGCAAGCAAGCACAGCAAGGGGATTTGGTTAATATCCCCAAACTGATGAGCCACTATTA
TCGACTCTTGCCGGATGCAAGCGATCCCGCTCAGAAAGTCAGTTTCGGTACCTCCGGCCATCGCGGCTGTGCATTTCACC
GAAGTTTTAACGAGCAGCATATCCTTGCCATTGCCCAGGCGGTGGTCGACTGGCGTACCCAGGCTGACATTACAGGTCCC
CTTTACCTTGGCATGGACACCCATGCGCTGTCCCAGGCGGCGTATTTGTCTGTGATTGAAGTGCTGATTGCCAACAAGGT
TCAGGTGTTGGCCCAGCGGGATGACGCATACACACCAACACCCGTGGTCAGTCAGGCAATTGTGGCTGCCAATCGTCATC
AAACTGGTGAAGACGCATTGCTCAGTGACGGTATCATCATCACGCCGTCACATAACCCACCTCAGGACGGGGGTATCAAG
TACAATCCGCCCCATGGTGGGCCGGCGGAAGGGGATATCACTTCCTGGATTGAAACCCGTGCCAATCACTATCTCGCCCA
CGGCCTGGATGGTGTTCGTCGGGTTAATTACGGTATCGCCTCTGGTCTTTCGCTGCTTAAACATGTAGACCTGATTTCGC
CTTATGTTCAAAGCCTTGCTGAAGTCATTGACATGGCCGCGATTGCTAAAGCCGGTGTGCGTATGGGGGTCGACCCTCTG
GGCGGTAGCGGCATCCATTACTGGCAGCCTATCGCCGAGCATTATGGGCTCAATATCGAGGTGGTAAATCAGGCAATTGA
TCCGACCTTCGATTTTATGCCATTGGATAAAGACGGAAAAATCCGCATGGACTGCTCGTCGCCCTATGCCATGGCAGGAC
TATTGGTACATAAAGATGAGTTTGATATCTGTGTCGGTAACGACCCGGATTATGACCGCCACGGTATTGTTTGCCCCGGT
AGTGGCCTGATGGATCCCAACCATTATCTTGCAGTGGCTATCGATTATCTGCTCGGCCACAGGCCAAACTGGGCCAAGAC
GTTGGCGGTTGGCAAAACCCTGGTATCCAGTGCCCTGATAGACAAGGTCTGCATGGCCCATGGGGTTCCCCTGATGGAAG
TACCCGTGGGCTTTAAGTGGTTTGTTGATGGCCTCGCTGATAGCAGTGTGTGTTTTGGCGGTGAAGAAAGCGCCGGGGCG
GCTTTCCTTAAAATGGATGGCAGCACCTGGTGCACCGATAAAGACGGCTTTATTCTGGCGCTGCTGGCGGCAGAAATTCT
CGCGGTTACCGGTAAAACCCCTGCCGAGCGCTACGAAGAGCTGGTTGCCGAACATGGTCGCAGTTTTTATAAACGTATCG
ATAGCCCACTTAATCCCAAAATGAAAGCCAAGTTCGGTGCGCTGAATGCGCAAACCCTTGGCGCGACTTCTGTCGCAGGC
GATGCCATTACCGCAGTGCTGACCAAGGCGCCCGGCAACGGTGCTGCCATTGGTGGCATCAAGGTGTGTACCGATAAAGG
CTGGTTCGCCGCGCGTCCATCCGGTACTGAGCCCTTGTTTAAGCTCTATGCCGAAAGCTTTGTCAGTGAGGCGCACCTTG
GCGAGTTGATTTCCGATGCGCAAAGTTTGTTGGGTACTGCGCTTAAGGCTATCAAGCTGTCACAGTTTGATATGAAGGTA
TAA

Upstream 100 bases:

>100_bases
TGGTGCAACTGGGTTGCGATCCGGTTCGTGCCAAATCCCTGGGTGAGCTGGCGCTCGCCTGAAACGACACTATTAACCAT
CCACGATAAGGAATTCCGTC

Downstream 100 bases:

>100_bases
AAAACGCGCCGTTGGGCGCGTTTTTTATTGGATAACGACTTGTTTCATCGGCTTGCGGTATCAATACTCGATGTGGCAAC
TGGGCAGGTTGTTTTTATCG

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 560; Mature: 559

Protein sequence:

>560_residues
MAIHDRAGKQAQQGDLVNIPKLMSHYYRLLPDASDPAQKVSFGTSGHRGCAFHRSFNEQHILAIAQAVVDWRTQADITGP
LYLGMDTHALSQAAYLSVIEVLIANKVQVLAQRDDAYTPTPVVSQAIVAANRHQTGEDALLSDGIIITPSHNPPQDGGIK
YNPPHGGPAEGDITSWIETRANHYLAHGLDGVRRVNYGIASGLSLLKHVDLISPYVQSLAEVIDMAAIAKAGVRMGVDPL
GGSGIHYWQPIAEHYGLNIEVVNQAIDPTFDFMPLDKDGKIRMDCSSPYAMAGLLVHKDEFDICVGNDPDYDRHGIVCPG
SGLMDPNHYLAVAIDYLLGHRPNWAKTLAVGKTLVSSALIDKVCMAHGVPLMEVPVGFKWFVDGLADSSVCFGGEESAGA
AFLKMDGSTWCTDKDGFILALLAAEILAVTGKTPAERYEELVAEHGRSFYKRIDSPLNPKMKAKFGALNAQTLGATSVAG
DAITAVLTKAPGNGAAIGGIKVCTDKGWFAARPSGTEPLFKLYAESFVSEAHLGELISDAQSLLGTALKAIKLSQFDMKV

Sequences:

>Translated_560_residues
MAIHDRAGKQAQQGDLVNIPKLMSHYYRLLPDASDPAQKVSFGTSGHRGCAFHRSFNEQHILAIAQAVVDWRTQADITGP
LYLGMDTHALSQAAYLSVIEVLIANKVQVLAQRDDAYTPTPVVSQAIVAANRHQTGEDALLSDGIIITPSHNPPQDGGIK
YNPPHGGPAEGDITSWIETRANHYLAHGLDGVRRVNYGIASGLSLLKHVDLISPYVQSLAEVIDMAAIAKAGVRMGVDPL
GGSGIHYWQPIAEHYGLNIEVVNQAIDPTFDFMPLDKDGKIRMDCSSPYAMAGLLVHKDEFDICVGNDPDYDRHGIVCPG
SGLMDPNHYLAVAIDYLLGHRPNWAKTLAVGKTLVSSALIDKVCMAHGVPLMEVPVGFKWFVDGLADSSVCFGGEESAGA
AFLKMDGSTWCTDKDGFILALLAAEILAVTGKTPAERYEELVAEHGRSFYKRIDSPLNPKMKAKFGALNAQTLGATSVAG
DAITAVLTKAPGNGAAIGGIKVCTDKGWFAARPSGTEPLFKLYAESFVSEAHLGELISDAQSLLGTALKAIKLSQFDMKV
>Mature_559_residues
AIHDRAGKQAQQGDLVNIPKLMSHYYRLLPDASDPAQKVSFGTSGHRGCAFHRSFNEQHILAIAQAVVDWRTQADITGPL
YLGMDTHALSQAAYLSVIEVLIANKVQVLAQRDDAYTPTPVVSQAIVAANRHQTGEDALLSDGIIITPSHNPPQDGGIKY
NPPHGGPAEGDITSWIETRANHYLAHGLDGVRRVNYGIASGLSLLKHVDLISPYVQSLAEVIDMAAIAKAGVRMGVDPLG
GSGIHYWQPIAEHYGLNIEVVNQAIDPTFDFMPLDKDGKIRMDCSSPYAMAGLLVHKDEFDICVGNDPDYDRHGIVCPGS
GLMDPNHYLAVAIDYLLGHRPNWAKTLAVGKTLVSSALIDKVCMAHGVPLMEVPVGFKWFVDGLADSSVCFGGEESAGAA
FLKMDGSTWCTDKDGFILALLAAEILAVTGKTPAERYEELVAEHGRSFYKRIDSPLNPKMKAKFGALNAQTLGATSVAGD
AITAVLTKAPGNGAAIGGIKVCTDKGWFAARPSGTEPLFKLYAESFVSEAHLGELISDAQSLLGTALKAIKLSQFDMKV

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=449, Percent_Identity=24.4988864142539, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI21361621, Length=438, Percent_Identity=25.3424657534247, Blast_Score=76, Evalue=8e-14,
Organism=Escherichia coli, GI1786904, Length=549, Percent_Identity=57.9234972677596, Blast_Score=648, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535441, Length=568, Percent_Identity=26.4084507042254, Blast_Score=100, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6322722, Length=404, Percent_Identity=28.7128712871287, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323752, Length=465, Percent_Identity=25.8064516129032, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17864244, Length=566, Percent_Identity=24.7349823321555, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 60005; Mature: 59874

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIHDRAGKQAQQGDLVNIPKLMSHYYRLLPDASDPAQKVSFGTSGHRGCAFHRSFNEQH
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEECCCCCHHH
ILAIAQAVVDWRTQADITGPLYLGMDTHALSQAAYLSVIEVLIANKVQVLAQRDDAYTPT
HHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PVVSQAIVAANRHQTGEDALLSDGIIITPSHNPPQDGGIKYNPPHGGPAEGDITSWIETR
HHHHHHHHHHCCCCCCCCHHHCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHH
ANHYLAHGLDGVRRVNYGIASGLSLLKHVDLISPYVQSLAEVIDMAAIAKAGVRMGVDPL
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GGSGIHYWQPIAEHYGLNIEVVNQAIDPTFDFMPLDKDGKIRMDCSSPYAMAGLLVHKDE
CCCCCHHHHHHHHHCCCCEEEEHHHCCCCCCCEECCCCCCEEEECCCCHHHHEEEEECCC
FDICVGNDPDYDRHGIVCPGSGLMDPNHYLAVAIDYLLGHRPNWAKTLAVGKTLVSSALI
CCEEECCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
DKVCMAHGVPLMEVPVGFKWFVDGLADSSVCFGGEESAGAAFLKMDGSTWCTDKDGFILA
HHHHHHCCCCEEECCCCHHHHHHCCCCCCEEECCCCCCCEEEEEECCCEEECCCCCHHHH
LLAAEILAVTGKTPAERYEELVAEHGRSFYKRIDSPLNPKMKAKFGALNAQTLGATSVAG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCHHHCC
DAITAVLTKAPGNGAAIGGIKVCTDKGWFAARPSGTEPLFKLYAESFVSEAHLGELISDA
HHHHHHEEECCCCCCEECCEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QSLLGTALKAIKLSQFDMKV
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AIHDRAGKQAQQGDLVNIPKLMSHYYRLLPDASDPAQKVSFGTSGHRGCAFHRSFNEQH
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEECCCCCHHH
ILAIAQAVVDWRTQADITGPLYLGMDTHALSQAAYLSVIEVLIANKVQVLAQRDDAYTPT
HHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PVVSQAIVAANRHQTGEDALLSDGIIITPSHNPPQDGGIKYNPPHGGPAEGDITSWIETR
HHHHHHHHHHCCCCCCCCHHHCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHH
ANHYLAHGLDGVRRVNYGIASGLSLLKHVDLISPYVQSLAEVIDMAAIAKAGVRMGVDPL
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GGSGIHYWQPIAEHYGLNIEVVNQAIDPTFDFMPLDKDGKIRMDCSSPYAMAGLLVHKDE
CCCCCHHHHHHHHHCCCCEEEEHHHCCCCCCCEECCCCCCEEEECCCCHHHHEEEEECCC
FDICVGNDPDYDRHGIVCPGSGLMDPNHYLAVAIDYLLGHRPNWAKTLAVGKTLVSSALI
CCEEECCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
DKVCMAHGVPLMEVPVGFKWFVDGLADSSVCFGGEESAGAAFLKMDGSTWCTDKDGFILA
HHHHHHCCCCEEECCCCHHHHHHCCCCCCEEECCCCCCCEEEEEECCCEEECCCCCHHHH
LLAAEILAVTGKTPAERYEELVAEHGRSFYKRIDSPLNPKMKAKFGALNAQTLGATSVAG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCHHHCC
DAITAVLTKAPGNGAAIGGIKVCTDKGWFAARPSGTEPLFKLYAESFVSEAHLGELISDA
HHHHHHEEECCCCCCEECCEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QSLLGTALKAIKLSQFDMKV
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083177; 8905232; 9278503; 8011018 [H]