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The map label for this gene is seqA [H]

Identifier: 119774841

GI number: 119774841

Start: 2084434

End: 2085009

Strand: Direct

Name: seqA [H]

Synonym: Sama_1705

Alternate gene names: 119774841

Gene position: 2084434-2085009 (Clockwise)

Preceding gene: 119774834

Following gene: 119774842

Centisome position: 48.41

GC content: 52.95

Gene sequence:

>576_bases
ATGAAATATATCGAAGTGGACGAAGAGCTCTATCGTTACATAGCCGGCAAGACTGAACGTATCGGTGAGAGTGCATCGGA
TATTTTACGGCGTTTGCTGGGACTCTCTGTCGCCGAAGTCTCTGAAGTGGCGCCTGTCGATATCAGTGAGCCAGGCATGG
AGCATGAGCCGGTGCAGGTGCGTGAGGCTGAACCTGAGCCAGTACCAGAAGTGGAAGTTGCTGCTCAGACCGAGATTGAT
TTTTCAGACTTGCTTAGTGAAGCGGGTCTGGCAGCGCAAAAAGGCGCCGTAGGCCGTTTTCTCTATGCTCTGGAATGTTT
GCACCAGGCTGCGCCTTCGCGTTTTGAACAGGTGCTGCAAATTCAGGGACGCGATCGTCTCTACTTTGCCACATCCAAAG
AGGCCCTGCTCAAAGCAAGCCAGTCGGCCAATCCCAAAGAAATTGGCTCAAGCGGTTTTTGGGTAACCACTAACAATAAT
ACCGCCAAAAAGCGCACCATACTTGAAGAAGCCCTGGTGCAACTGGGTTGCGATCCGGTTCGTGCCAAATCCCTGGGTGA
GCTGGCGCTCGCCTGA

Upstream 100 bases:

>100_bases
TAGAGCGCTTTATCAATCTGTTGGACTGGCTTACACTGGGCTTTCTTCGGCGAAGCGGCATGCTTTGCGTGCCTGATAAG
ACAAAAGGAAAGCATTGGTG

Downstream 100 bases:

>100_bases
AACGACACTATTAACCATCCACGATAAGGAATTCCGTCTTGGCTATCCATGACCGCGCAGGCAAGCAAGCACAGCAAGGG
GATTTGGTTAATATCCCCAA

Product: replication initiation regulator SeqA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MKYIEVDEELYRYIAGKTERIGESASDILRRLLGLSVAEVSEVAPVDISEPGMEHEPVQVREAEPEPVPEVEVAAQTEID
FSDLLSEAGLAAQKGAVGRFLYALECLHQAAPSRFEQVLQIQGRDRLYFATSKEALLKASQSANPKEIGSSGFWVTTNNN
TAKKRTILEEALVQLGCDPVRAKSLGELALA

Sequences:

>Translated_191_residues
MKYIEVDEELYRYIAGKTERIGESASDILRRLLGLSVAEVSEVAPVDISEPGMEHEPVQVREAEPEPVPEVEVAAQTEID
FSDLLSEAGLAAQKGAVGRFLYALECLHQAAPSRFEQVLQIQGRDRLYFATSKEALLKASQSANPKEIGSSGFWVTTNNN
TAKKRTILEEALVQLGCDPVRAKSLGELALA
>Mature_191_residues
MKYIEVDEELYRYIAGKTERIGESASDILRRLLGLSVAEVSEVAPVDISEPGMEHEPVQVREAEPEPVPEVEVAAQTEID
FSDLLSEAGLAAQKGAVGRFLYALECLHQAAPSRFEQVLQIQGRDRLYFATSKEALLKASQSANPKEIGSSGFWVTTNNN
TAKKRTILEEALVQLGCDPVRAKSLGELALA

Specific function: Negative regulator of replication initiation. Required for sequestration, a process that blocks secondary initiation events. Could block the allosteric transition of dnaA from an inactive form to an active form [H]

COG id: COG3057

COG function: function code L; Negative regulator of replication initiationR

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786903, Length=177, Percent_Identity=38.4180790960452, Blast_Score=109, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005621
- InterPro:   IPR010985 [H]

Pfam domain/function: PF03925 SeqA [H]

EC number: NA

Molecular weight: Translated: 20887; Mature: 20887

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYIEVDEELYRYIAGKTERIGESASDILRRLLGLSVAEVSEVAPVDISEPGMEHEPVQV
CCCCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCEE
REAEPEPVPEVEVAAQTEIDFSDLLSEAGLAAQKGAVGRFLYALECLHQAAPSRFEQVLQ
ECCCCCCCCCEEEHHCCCCCHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHCHHHHHHHHH
IQGRDRLYFATSKEALLKASQSANPKEIGSSGFWVTTNNNTAKKRTILEEALVQLGCDPV
HCCCCEEEEECCHHHHHHHHCCCCHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHH
RAKSLGELALA
HHHHHHHHHCC
>Mature Secondary Structure
MKYIEVDEELYRYIAGKTERIGESASDILRRLLGLSVAEVSEVAPVDISEPGMEHEPVQV
CCCCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCEE
REAEPEPVPEVEVAAQTEIDFSDLLSEAGLAAQKGAVGRFLYALECLHQAAPSRFEQVLQ
ECCCCCCCCCEEEHHCCCCCHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHCHHHHHHHHH
IQGRDRLYFATSKEALLKASQSANPKEIGSSGFWVTTNNNTAKKRTILEEALVQLGCDPV
HCCCCEEEEECCHHHHHHHHCCCCHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHH
RAKSLGELALA
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]