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The map label for this gene is ybfF [H]

Identifier: 119774840

GI number: 119774840

Start: 2083379

End: 2084167

Strand: Reverse

Name: ybfF [H]

Synonym: Sama_1704

Alternate gene names: 119774840

Gene position: 2084167-2083379 (Counterclockwise)

Preceding gene: 119774843

Following gene: 119774839

Centisome position: 48.4

GC content: 53.99

Gene sequence:

>789_bases
ATGTCAGCGCAGCTTAACTATCAGACCCAGGGTGTAGGGGAAGACGTGGTTCTGGTTCACGGTCTTTTTGGCGATCTGGA
TAATCTAAAGGGACTGGCGCAGACCCTGGAGAGCGAATATCGCGTTACTCGTATCGATGTGCCCAATCACGGTCAGAGTC
CCCACTGGGATACGATGGATTACCCAAGCCTGGCCCAGAGTCTGGTTTCATTGCTGGATGAACTGGGCGCAACCAAAGCA
CATCTCATTGGTCATTCCATGGGCGGTAAAATTGTGCTCGCAACGGCGCTTCTGCATCCTGACAGAGTCGCGTCCGTGGT
TGCCGCCGATATCGCGCCCGTACCCTATGCCCCCCGTCATCAACGAGTGTTTGCTGCCCTCACCTCGCTGCCCCTTGATG
GCAGCGTCGAGCGGAAAGAGGCCTTGAATCACCTTTTGGCAAGGGGTGTGGATGAGGCGACAGCACAGTTTTTGCTGAAA
AGCTTTCGCCGGGCGGAGTCTGGTTTCAGTTGGCGGATGAATCTGGACGGCCTGATAGCCTCCTATGAGGGCATTATCGG
TTGGCCATTCAATAACGGCGCTTATGATGGTCCGACACTCTTTATTCGCGGTGATGAGTCAGACTATGTCACCGCTGAAC
ATAAAGACGCCATCCTCAGCCAGTTTCCGAATGTGCAGCTTAAGTCCATTGGTGGAGCCGGTCACTGGTTACACGCACAG
AAGCCCGGCATCTTTAACCGACTGGTGAAAAATTTTCTGGACAGCCAACACCCTGAGTTACACGGGTAA

Upstream 100 bases:

>100_bases
CGCACACGGGACTTAATGGTCACTTTTCTTGCCTGCGCCCGGGCTTGGGGGCAAAATTGCCGCCTTTAGGTGTTAATCCC
AATCAACGGGCAGGATTTAC

Downstream 100 bases:

>100_bases
AGGCTATAGCAGACGCTAATATGATGTGATATATTCGCGCCTCTTTTTCAAGGCCGGGTTTTACCCCTACGCCAAGCAAC
GCCGGAGTCAGCGCTGATGT

Product: alpha/beta fold family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MSAQLNYQTQGVGEDVVLVHGLFGDLDNLKGLAQTLESEYRVTRIDVPNHGQSPHWDTMDYPSLAQSLVSLLDELGATKA
HLIGHSMGGKIVLATALLHPDRVASVVAADIAPVPYAPRHQRVFAALTSLPLDGSVERKEALNHLLARGVDEATAQFLLK
SFRRAESGFSWRMNLDGLIASYEGIIGWPFNNGAYDGPTLFIRGDESDYVTAEHKDAILSQFPNVQLKSIGGAGHWLHAQ
KPGIFNRLVKNFLDSQHPELHG

Sequences:

>Translated_262_residues
MSAQLNYQTQGVGEDVVLVHGLFGDLDNLKGLAQTLESEYRVTRIDVPNHGQSPHWDTMDYPSLAQSLVSLLDELGATKA
HLIGHSMGGKIVLATALLHPDRVASVVAADIAPVPYAPRHQRVFAALTSLPLDGSVERKEALNHLLARGVDEATAQFLLK
SFRRAESGFSWRMNLDGLIASYEGIIGWPFNNGAYDGPTLFIRGDESDYVTAEHKDAILSQFPNVQLKSIGGAGHWLHAQ
KPGIFNRLVKNFLDSQHPELHG
>Mature_261_residues
SAQLNYQTQGVGEDVVLVHGLFGDLDNLKGLAQTLESEYRVTRIDVPNHGQSPHWDTMDYPSLAQSLVSLLDELGATKAH
LIGHSMGGKIVLATALLHPDRVASVVAADIAPVPYAPRHQRVFAALTSLPLDGSVERKEALNHLLARGVDEATAQFLLKS
FRRAESGFSWRMNLDGLIASYEGIIGWPFNNGAYDGPTLFIRGDESDYVTAEHKDAILSQFPNVQLKSIGGAGHWLHAQK
PGIFNRLVKNFLDSQHPELHG

Specific function: Displays esterase activity toward palmitoyl-CoA, malonyl-CoA and pNP-butyrate [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

Organism=Homo sapiens, GI23200012, Length=246, Percent_Identity=36.1788617886179, Blast_Score=151, Evalue=7e-37,
Organism=Homo sapiens, GI23200008, Length=246, Percent_Identity=36.1788617886179, Blast_Score=150, Evalue=8e-37,
Organism=Homo sapiens, GI223941839, Length=240, Percent_Identity=31.25, Blast_Score=122, Evalue=2e-28,
Organism=Escherichia coli, GI1786902, Length=248, Percent_Identity=42.741935483871, Blast_Score=190, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI17508535, Length=250, Percent_Identity=36.4, Blast_Score=157, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17507063, Length=272, Percent_Identity=30.1470588235294, Blast_Score=108, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6321468, Length=263, Percent_Identity=30.4182509505703, Blast_Score=97, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24640348, Length=254, Percent_Identity=31.1023622047244, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24646055, Length=256, Percent_Identity=26.171875, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 28648; Mature: 28516

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQLNYQTQGVGEDVVLVHGLFGDLDNLKGLAQTLESEYRVTRIDVPNHGQSPHWDTMD
CCCCCCCCCCCCCCCEEEEEHHHCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCC
YPSLAQSLVSLLDELGATKAHLIGHSMGGKIVLATALLHPDRVASVVAADIAPVPYAPRH
CHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEHHCHHHHHHHHHHHCCCCCCCCCH
QRVFAALTSLPLDGSVERKEALNHLLARGVDEATAQFLLKSFRRAESGFSWRMNLDGLIA
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHH
SYEGIIGWPFNNGAYDGPTLFIRGDESDYVTAEHKDAILSQFPNVQLKSIGGAGHWLHAQ
HCCCEEECCCCCCCCCCCEEEEECCCCCEEECHHHHHHHHHCCCCEEEECCCCCCEECCC
KPGIFNRLVKNFLDSQHPELHG
CCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SAQLNYQTQGVGEDVVLVHGLFGDLDNLKGLAQTLESEYRVTRIDVPNHGQSPHWDTMD
CCCCCCCCCCCCCCEEEEEHHHCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCC
YPSLAQSLVSLLDELGATKAHLIGHSMGGKIVLATALLHPDRVASVVAADIAPVPYAPRH
CHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEHHCHHHHHHHHHHHCCCCCCCCCH
QRVFAALTSLPLDGSVERKEALNHLLARGVDEATAQFLLKSFRRAESGFSWRMNLDGLIA
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHH
SYEGIIGWPFNNGAYDGPTLFIRGDESDYVTAEHKDAILSQFPNVQLKSIGGAGHWLHAQ
HCCCEEECCCCCCCCCCCEEEEECCCCCEEECHHHHHHHHHCCCCEEEECCCCCCEECCC
KPGIFNRLVKNFLDSQHPELHG
CCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10493123 [H]