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The map label for this gene is hutU [H]

Identifier: 119774769

GI number: 119774769

Start: 1997435

End: 1999447

Strand: Direct

Name: hutU [H]

Synonym: Sama_1632

Alternate gene names: 119774769

Gene position: 1997435-1999447 (Clockwise)

Preceding gene: 119774768

Following gene: 119774771

Centisome position: 46.39

GC content: 55.94

Gene sequence:

>2013_bases
ATGGAAACCAATATGACTTTTGCTGAACAAATCAAACAAGGGATCCCAGCCGAGCTGCCTTCGCCAAAGCCCTATCCGGC
CGATGCCAACCGCGCTCCCAAGCGTAAAGACATTCTCACCGCCGCTGAAAAGCAGCTGGCGGTACGTAATGCATTGCGTT
ATTTCCCGGCCGAGTGGCATCAGGAACTGGCTGCGGAGTTTGCCAAAGAATTGAACGATTTTGGCCGCATTTACATGTAC
CGCTTCAAGCCGGAATACGCGATGAAGGCCCGCGCAATCTCTGAGTACCCTGCCAAATGCGAGCAGGCCGCCGCCATTAT
GCTGATGGTCGATAACAACCTCGACCCGGCCGTGGCTCAGCATCCAGAAGAGCTTATCACCTACGGTGGCAATGGCGCTG
TGTTCCAGAACTGGGCGCAGTATCGCCTCACCATGAAGTACTTAAGCGAAATGGAAGCGGACCAGACCCTGCACCTCTAC
TCGGGCCACCCCATGGGATTGTTCCCATCGTCAGTGGATGCACCAAGGGTGGTGGTAACCAACGGCATGATGATCCCCAA
TTATTCCAAGCCCGATGACTGGGAGCGCTTCAACGCCCTTGGCGTAACCCAATACGGCCAGATGACGGCCGGCTCCTTTA
TGTACATCGGCCCCCAGGGCATAGTGCACGGCACTACCATCACCGTGATGAACGGTTTCCGTAAGGTGCTGGAAAAAGGC
GATAGCCCTAAAGGCAAGATTTTCCTCACAGCCGGTCTTGGCGGCATGAGTGGTGCCCAGCCCAAGGCCGGTAACATCGC
CGGATGTATTACCGTGTGCGCCGAGGTCAACCCCAAGGCCGCCACCAAGCGCCACGCTCAGGGTTGGGTGGATGAGCTTA
TCGATAACATGGATGCGCTGGTTGCCCGGGTTAAACAGGCCCAGGCCAATGAAGAAGTGGTGTCCATCGCCTTTATCGGT
AACGTGGTCAACGTATGGGAAGCGTTCGATGAGCATGATATTTTTGTGCATCTGGGCTCGGATCAAACATCCCTGCACAA
CCCATGGTCCGGCGGCTACTACCCGGTGGATATCAGCTACGATGAGTCAAACCGCCTCATTCGTGAGGAGCCTGAGCTGT
TTAAAACCAAGGTTCAGGCCACCCTCAAGCGCCATGCTGACGCCATTAATCGCCATACCGCCAAGGGCACTTACTTTTTT
GACTACGGCAATGCCTTCCTGCTGGAAGCCTCCCGTGCCGGCGGCGATGTAATGGCCGAGAACGGCATCGACTTCAAGTA
CCCATCCTACGTGCAGGATATTCTGGGCCCTATGTGTTTCGATTACGGTTTTGGTCCGTTCCGCTGGGTGTGCACTTCAG
GTAACAGCGCCGATCTTGACCGCACCGACGCCATTGCCGCCGAGGTGCTTGCACGGATTATGGCCGAGGCGCCAGCTGAA
ATTCAGCAGCAAATGCAGGACAACATTACCTGGATTAAAGACGCCAAACAAAACAAGCTGGTGGTGGGTTCACAGGCCCG
TATCCTCTATGCCGACGCCGAAGGCCGCATGGAAATTGCCAAGGCCTTTAACGATGCCATTAGCCGGGGCGAAATCGGCC
CGGTGGTCCTTGGCCGCGACCACCACGATGTGAGCGGTACCGACTCGCCATTCCGTGAAACCTCCAACATCTATGATGGC
AGCCGCTTTACCGCCGATATGGCCATTCATAACGTGATTGGCGATAGCTTCCGCGGCGCCACCTGGGTATCCATCCACAA
TGGTGGTGGGGTAGGTTGGGGCGAAGTAATCAACGGTGGCTTTGGTATGCTGCTGGATGGAACAGAAGCTGCCGAGCGGC
GCCTTAAGTCCATGCTGCTGTTTGATGTGAACAACGGCATTGCCCGTCGCAGCTGGGCCCGCAACGAAGAAGCCAACTTC
GCCATCAAACGCGAAATGGCCCGCACGCCCAAGCTTAAGGTGACCCTGGCCAACAGTGTCGATGACGACATCATTAACGG
ACTTGAGTTCTAA

Upstream 100 bases:

>100_bases
AGCTGGAAGAGGACCGCCTGCTCAAGCCCGATATTGATGCCATTATTGCGCTGGTCAAGGCTCAGGCCTTTACCGTGAAG
TAAGGGGGAGGATGACAAGC

Downstream 100 bases:

>100_bases
GGCATCCGTTACGATAAAAACGCCCCTTGAGGGCGTTTTTTTATGTCACCAGACCGAGGTCTCAGATCTGATGGAAACAG
GGTAATTGGCTATCATATTA

Product: urocanate hydratase

Products: NA

Alternate protein names: Urocanase; Imidazolonepropionate hydrolase [H]

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
METNMTFAEQIKQGIPAELPSPKPYPADANRAPKRKDILTAAEKQLAVRNALRYFPAEWHQELAAEFAKELNDFGRIYMY
RFKPEYAMKARAISEYPAKCEQAAAIMLMVDNNLDPAVAQHPEELITYGGNGAVFQNWAQYRLTMKYLSEMEADQTLHLY
SGHPMGLFPSSVDAPRVVVTNGMMIPNYSKPDDWERFNALGVTQYGQMTAGSFMYIGPQGIVHGTTITVMNGFRKVLEKG
DSPKGKIFLTAGLGGMSGAQPKAGNIAGCITVCAEVNPKAATKRHAQGWVDELIDNMDALVARVKQAQANEEVVSIAFIG
NVVNVWEAFDEHDIFVHLGSDQTSLHNPWSGGYYPVDISYDESNRLIREEPELFKTKVQATLKRHADAINRHTAKGTYFF
DYGNAFLLEASRAGGDVMAENGIDFKYPSYVQDILGPMCFDYGFGPFRWVCTSGNSADLDRTDAIAAEVLARIMAEAPAE
IQQQMQDNITWIKDAKQNKLVVGSQARILYADAEGRMEIAKAFNDAISRGEIGPVVLGRDHHDVSGTDSPFRETSNIYDG
SRFTADMAIHNVIGDSFRGATWVSIHNGGGVGWGEVINGGFGMLLDGTEAAERRLKSMLLFDVNNGIARRSWARNEEANF
AIKREMARTPKLKVTLANSVDDDIINGLEF

Sequences:

>Translated_670_residues
METNMTFAEQIKQGIPAELPSPKPYPADANRAPKRKDILTAAEKQLAVRNALRYFPAEWHQELAAEFAKELNDFGRIYMY
RFKPEYAMKARAISEYPAKCEQAAAIMLMVDNNLDPAVAQHPEELITYGGNGAVFQNWAQYRLTMKYLSEMEADQTLHLY
SGHPMGLFPSSVDAPRVVVTNGMMIPNYSKPDDWERFNALGVTQYGQMTAGSFMYIGPQGIVHGTTITVMNGFRKVLEKG
DSPKGKIFLTAGLGGMSGAQPKAGNIAGCITVCAEVNPKAATKRHAQGWVDELIDNMDALVARVKQAQANEEVVSIAFIG
NVVNVWEAFDEHDIFVHLGSDQTSLHNPWSGGYYPVDISYDESNRLIREEPELFKTKVQATLKRHADAINRHTAKGTYFF
DYGNAFLLEASRAGGDVMAENGIDFKYPSYVQDILGPMCFDYGFGPFRWVCTSGNSADLDRTDAIAAEVLARIMAEAPAE
IQQQMQDNITWIKDAKQNKLVVGSQARILYADAEGRMEIAKAFNDAISRGEIGPVVLGRDHHDVSGTDSPFRETSNIYDG
SRFTADMAIHNVIGDSFRGATWVSIHNGGGVGWGEVINGGFGMLLDGTEAAERRLKSMLLFDVNNGIARRSWARNEEANF
AIKREMARTPKLKVTLANSVDDDIINGLEF
>Mature_670_residues
METNMTFAEQIKQGIPAELPSPKPYPADANRAPKRKDILTAAEKQLAVRNALRYFPAEWHQELAAEFAKELNDFGRIYMY
RFKPEYAMKARAISEYPAKCEQAAAIMLMVDNNLDPAVAQHPEELITYGGNGAVFQNWAQYRLTMKYLSEMEADQTLHLY
SGHPMGLFPSSVDAPRVVVTNGMMIPNYSKPDDWERFNALGVTQYGQMTAGSFMYIGPQGIVHGTTITVMNGFRKVLEKG
DSPKGKIFLTAGLGGMSGAQPKAGNIAGCITVCAEVNPKAATKRHAQGWVDELIDNMDALVARVKQAQANEEVVSIAFIG
NVVNVWEAFDEHDIFVHLGSDQTSLHNPWSGGYYPVDISYDESNRLIREEPELFKTKVQATLKRHADAINRHTAKGTYFF
DYGNAFLLEASRAGGDVMAENGIDFKYPSYVQDILGPMCFDYGFGPFRWVCTSGNSADLDRTDAIAAEVLARIMAEAPAE
IQQQMQDNITWIKDAKQNKLVVGSQARILYADAEGRMEIAKAFNDAISRGEIGPVVLGRDHHDVSGTDSPFRETSNIYDG
SRFTADMAIHNVIGDSFRGATWVSIHNGGGVGWGEVINGGFGMLLDGTEAAERRLKSMLLFDVNNGIARRSWARNEEANF
AIKREMARTPKLKVTLANSVDDDIINGLEF

Specific function: Unknown

COG id: COG2987

COG function: function code E; Urocanate hydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the urocanase family [H]

Homologues:

Organism=Homo sapiens, GI21389467, Length=669, Percent_Identity=55.6053811659193, Blast_Score=745, Evalue=0.0,
Organism=Homo sapiens, GI260306182, Length=373, Percent_Identity=53.887399463807, Blast_Score=404, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI71997891, Length=645, Percent_Identity=56.7441860465116, Blast_Score=754, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000193 [H]

Pfam domain/function: PF01175 Urocanase [H]

EC number: =4.2.1.49 [H]

Molecular weight: Translated: 74111; Mature: 74111

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS01233 UROCANASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METNMTFAEQIKQGIPAELPSPKPYPADANRAPKRKDILTAAEKQLAVRNALRYFPAEWH
CCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHH
QELAAEFAKELNDFGRIYMYRFKPEYAMKARAISEYPAKCEQAAAIMLMVDNNLDPAVAQ
HHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCHHHHCCEEEEEEEECCCCCHHHH
HPEELITYGGNGAVFQNWAQYRLTMKYLSEMEADQTLHLYSGHPMGLFPSSVDAPRVVVT
CCHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEE
NGMMIPNYSKPDDWERFNALGVTQYGQMTAGSFMYIGPQGIVHGTTITVMNGFRKVLEKG
CCEECCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEECCCCEECCCCHHHHHHHHHHHHCC
DSPKGKIFLTAGLGGMSGAQPKAGNIAGCITVCAEVNPKAATKRHAQGWVDELIDNMDAL
CCCCCEEEEEECCCCCCCCCCCCCCHHEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
VARVKQAQANEEVVSIAFIGNVVNVWEAFDEHDIFVHLGSDQTSLHNPWSGGYYPVDISY
HHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEEEEEE
DESNRLIREEPELFKTKVQATLKRHADAINRHTAKGTYFFDYGNAFLLEASRAGGDVMAE
CCCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCCEEEC
NGIDFKYPSYVQDILGPMCFDYGFGPFRWVCTSGNSADLDRTDAIAAEVLARIMAEAPAE
CCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHH
IQQQMQDNITWIKDAKQNKLVVGSQARILYADAEGRMEIAKAFNDAISRGEIGPVVLGRD
HHHHHHCCCEEEECCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCC
HHDVSGTDSPFRETSNIYDGSRFTADMAIHNVIGDSFRGATWVSIHNGGGVGWGEVINGG
CCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHCCC
FGMLLDGTEAAERRLKSMLLFDVNNGIARRSWARNEEANFAIKREMARTPKLKVTLANSV
CEEEECCHHHHHHHHHHEEEEECCCCHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCC
DDDIINGLEF
CHHHHCCCCC
>Mature Secondary Structure
METNMTFAEQIKQGIPAELPSPKPYPADANRAPKRKDILTAAEKQLAVRNALRYFPAEWH
CCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHH
QELAAEFAKELNDFGRIYMYRFKPEYAMKARAISEYPAKCEQAAAIMLMVDNNLDPAVAQ
HHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCHHHHCCEEEEEEEECCCCCHHHH
HPEELITYGGNGAVFQNWAQYRLTMKYLSEMEADQTLHLYSGHPMGLFPSSVDAPRVVVT
CCHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEE
NGMMIPNYSKPDDWERFNALGVTQYGQMTAGSFMYIGPQGIVHGTTITVMNGFRKVLEKG
CCEECCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEECCCCEECCCCHHHHHHHHHHHHCC
DSPKGKIFLTAGLGGMSGAQPKAGNIAGCITVCAEVNPKAATKRHAQGWVDELIDNMDAL
CCCCCEEEEEECCCCCCCCCCCCCCHHEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
VARVKQAQANEEVVSIAFIGNVVNVWEAFDEHDIFVHLGSDQTSLHNPWSGGYYPVDISY
HHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEEEEEE
DESNRLIREEPELFKTKVQATLKRHADAINRHTAKGTYFFDYGNAFLLEASRAGGDVMAE
CCCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCCEEEC
NGIDFKYPSYVQDILGPMCFDYGFGPFRWVCTSGNSADLDRTDAIAAEVLARIMAEAPAE
CCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHH
IQQQMQDNITWIKDAKQNKLVVGSQARILYADAEGRMEIAKAFNDAISRGEIGPVVLGRD
HHHHHHCCCEEEECCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCC
HHDVSGTDSPFRETSNIYDGSRFTADMAIHNVIGDSFRGATWVSIHNGGGVGWGEVINGG
CCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHCCC
FGMLLDGTEAAERRLKSMLLFDVNNGIARRSWARNEEANFAIKREMARTPKLKVTLANSV
CEEEECCHHHHHHHHHHEEEEECCCCHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCC
DDDIINGLEF
CHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA