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The map label for this gene is sapC [H]

Identifier: 119774370

GI number: 119774370

Start: 1517353

End: 1518243

Strand: Reverse

Name: sapC [H]

Synonym: Sama_1233

Alternate gene names: 119774370

Gene position: 1518243-1517353 (Counterclockwise)

Preceding gene: 119774371

Following gene: 119774369

Centisome position: 35.26

GC content: 55.22

Gene sequence:

>891_bases
ATGCCTCAAATTAAGATTTATCAGGAAGACGACATTCCGTCTCCCATGAGGCGGCTATGGCAGGCGTTTGCATCCAACCC
CTTCGCCCTGGCGGGGCTTTGGGTCATCATCGGGCTGCTGTTTTTCACCCTGTTTGGCCCCTGGCTGGCGCCCTTCAGTC
CGGAAGCACAAAACCCCAAAGCCTTGCTATTGCCACCCTCCTGGGATCCCGCAGGTACGGTGGAACACTTTTTGGGTACC
GATGACCTGGGGCGGGATATATTCAGCCGCATCCTTCATGGTGTGCAGCTGACATTCGGCATGTCGTTGGCCGTGGTGAT
TACCGCGCTGCTGCTTGGCTTTGTCATAGGTGCCATTTCGGGCATGATGAAAGGGCTTAAATCCAGTATTCTCGGTCACC
TGCTGGACGCGCTCTTGTCCATTCCATCACTTTTAATGGCCATCCTGGTCGTCGCTGTACTGGGGCCGGGGCTTGGCAAC
GTATTTTGGGCTGTGGGTATTGCCCTCACCCCACAATTTGTGCGCGCCATTCATCAGGCCATCCATGAAGAACTGCAAAA
AGAATATGTCACTGCTGCTCGCCTCGATGGCGCCAACAGTGCCCAGATTTTCTGGTACGTGATCATGCCGAACGTCTGGG
AAGTGGTCATTATTCAAACCACGCTCGCCATTTCCACCGCGATTCTGGATATAGCCGCTTTGGGCTTTCTTAATCTGGGA
GCTCAGGCGCCCAGCCCCGAGTGGGGTGCCATGGTATTTCAGGGCTTGGATAACCTGCTTACCGCCCCCTGGACCATGAC
CATTCCCGGGCTCGCGATACTCTTTACCGTGCTTGCCGTTAATTTGGTGGGCGATGGATTACGCTCGGCCCTTGCGCCGA
TAAAGAACTGA

Upstream 100 bases:

>100_bases
CAGGGCGGAATTCTGGCGGTTGCCCTGCTCATTATTTTCCTGAGCATCCTGATTGAAGTGATACACACAGCCTCCAACCC
GCTGAGCAGGAAAGAACTTT

Downstream 100 bases:

>100_bases
TTATGCCGCTACTGGATATTCGCAATCTCACCATCGAACTCGACACCCCACACGGGCGGGTCAAGGCACTGGAAAAAGTC
AGCCTGATGCTCCATGCCGG

Product: peptide ABC transporter permease

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MPQIKIYQEDDIPSPMRRLWQAFASNPFALAGLWVIIGLLFFTLFGPWLAPFSPEAQNPKALLLPPSWDPAGTVEHFLGT
DDLGRDIFSRILHGVQLTFGMSLAVVITALLLGFVIGAISGMMKGLKSSILGHLLDALLSIPSLLMAILVVAVLGPGLGN
VFWAVGIALTPQFVRAIHQAIHEELQKEYVTAARLDGANSAQIFWYVIMPNVWEVVIIQTTLAISTAILDIAALGFLNLG
AQAPSPEWGAMVFQGLDNLLTAPWTMTIPGLAILFTVLAVNLVGDGLRSALAPIKN

Sequences:

>Translated_296_residues
MPQIKIYQEDDIPSPMRRLWQAFASNPFALAGLWVIIGLLFFTLFGPWLAPFSPEAQNPKALLLPPSWDPAGTVEHFLGT
DDLGRDIFSRILHGVQLTFGMSLAVVITALLLGFVIGAISGMMKGLKSSILGHLLDALLSIPSLLMAILVVAVLGPGLGN
VFWAVGIALTPQFVRAIHQAIHEELQKEYVTAARLDGANSAQIFWYVIMPNVWEVVIIQTTLAISTAILDIAALGFLNLG
AQAPSPEWGAMVFQGLDNLLTAPWTMTIPGLAILFTVLAVNLVGDGLRSALAPIKN
>Mature_295_residues
PQIKIYQEDDIPSPMRRLWQAFASNPFALAGLWVIIGLLFFTLFGPWLAPFSPEAQNPKALLLPPSWDPAGTVEHFLGTD
DLGRDIFSRILHGVQLTFGMSLAVVITALLLGFVIGAISGMMKGLKSSILGHLLDALLSIPSLLMAILVVAVLGPGLGNV
FWAVGIALTPQFVRAIHQAIHEELQKEYVTAARLDGANSAQIFWYVIMPNVWEVVIIQTTLAISTAILDIAALGFLNLGA
QAPSPEWGAMVFQGLDNLLTAPWTMTIPGLAILFTVLAVNLVGDGLRSALAPIKN

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4171

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787549, Length=291, Percent_Identity=49.4845360824742, Blast_Score=289, Evalue=1e-79,
Organism=Escherichia coli, GI1789964, Length=280, Percent_Identity=43.2142857142857, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI1787760, Length=268, Percent_Identity=39.5522388059701, Blast_Score=177, Evalue=9e-46,
Organism=Escherichia coli, GI1787054, Length=293, Percent_Identity=34.8122866894198, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1789889, Length=246, Percent_Identity=34.5528455284553, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787498, Length=281, Percent_Identity=29.8932384341637, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1788505, Length=303, Percent_Identity=25.0825082508251, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31867; Mature: 31736

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQIKIYQEDDIPSPMRRLWQAFASNPFALAGLWVIIGLLFFTLFGPWLAPFSPEAQNPK
CCCCEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ALLLPPSWDPAGTVEHFLGTDDLGRDIFSRILHGVQLTFGMSLAVVITALLLGFVIGAIS
EEEECCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMMKGLKSSILGHLLDALLSIPSLLMAILVVAVLGPGLGNVFWAVGIALTPQFVRAIHQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHH
IHEELQKEYVTAARLDGANSAQIFWYVIMPNVWEVVIIQTTLAISTAILDIAALGFLNLG
HHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AQAPSPEWGAMVFQGLDNLLTAPWTMTIPGLAILFTVLAVNLVGDGLRSALAPIKN
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PQIKIYQEDDIPSPMRRLWQAFASNPFALAGLWVIIGLLFFTLFGPWLAPFSPEAQNPK
CCCEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ALLLPPSWDPAGTVEHFLGTDDLGRDIFSRILHGVQLTFGMSLAVVITALLLGFVIGAIS
EEEECCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMMKGLKSSILGHLLDALLSIPSLLMAILVVAVLGPGLGNVFWAVGIALTPQFVRAIHQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHH
IHEELQKEYVTAARLDGANSAQIFWYVIMPNVWEVVIIQTTLAISTAILDIAALGFLNLG
HHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AQAPSPEWGAMVFQGLDNLLTAPWTMTIPGLAILFTVLAVNLVGDGLRSALAPIKN
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]