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The map label for this gene is sapD [H]

Identifier: 119774369

GI number: 119774369

Start: 1516343

End: 1517350

Strand: Reverse

Name: sapD [H]

Synonym: Sama_1232

Alternate gene names: 119774369

Gene position: 1517350-1516343 (Counterclockwise)

Preceding gene: 119774370

Following gene: 119774368

Centisome position: 35.24

GC content: 56.55

Gene sequence:

>1008_bases
ATGCCGCTACTGGATATTCGCAATCTCACCATCGAACTCGACACCCCACACGGGCGGGTCAAGGCACTGGAAAAAGTCAG
CCTGATGCTCCATGCCGGAGAAATTCATGGCTTGGTGGGCGAGTCGGGCTCGGGTCGCAGTCTGCTTGCCCGGGCCGTTC
TGGGGATCCCGGGTCCCAACTGGACCATTACTGCCGATCGCATGATGTGGGATGGCCGAAACCTCATGGAAATGAGCGAT
GTCGAACGCCGCAATCTTATGGGCAAAGACATGGCGATGATATTTCAGGACCCTTCCGGTAGCCTCGACCCGGTGATCAC
CATAGGTGCCCAGCTGATTGAAGCCATGCCCGCCGACAAGAATGTGCCCTTCTGGCGACGTGGTCGTGAGCGGCGTCTGA
CGGCACAAAAATGGCTGCATAAGGTGGGTATCAAGGATCCCAAACGGGTGATGGCCTCCTATCCCTGGGAAACCTCAGAA
GGCGAATGCCAAAAGGTGATGATTGCCATGGCGCTGGCCAATCAGCCCAGATTGCTGATTGCCGATGAACCGACCAACTC
AATGGAACCCAGCACCCAAGCCCAGATTTTCCGCCTCCTGGCACAGCTCAATCAGCTGCAGGGGGTAACCATTATGATGA
TCAGCCATGAGCTTGAGACCCTGGCGGACTGGTGCAATAACCTCACAGTGCTTTACTGCGGTCAGGTGATGGAATCCGGT
CCCATTGATGAGCTTATCCGTGAGCCGCTGCACCCCTATACCAAGGCGCTGATGGATCACCTTCCCGATTACCGTGGCAA
CCTGCCTCACAAGAGCCTGATGCCGGTATTGCCCGGGTCGGCGCCGGCCTTACAGCATTTACCCATAGGTTGCCGCCTGG
GTCCACGCTGCCCGGAAGCCAGACGCGAGTGTGTCCATCAGCCTCAGCTGCAACATCAAAAAGACAGATATTATGCCTGT
CACTTCCCTTATCGCACGGAGACGAATAATGACGACACCGCTGCTTAA

Upstream 100 bases:

>100_bases
CCATGACCATTCCCGGGCTCGCGATACTCTTTACCGTGCTTGCCGTTAATTTGGTGGGCGATGGATTACGCTCGGCCCTT
GCGCCGATAAAGAACTGATT

Downstream 100 bases:

>100_bases
GGTCACCAGTCTGTCAAAACGCTACTTCACCGGCTATCACAGGTTTAAGCGCCAGTATAACGAGGCCTTGGCGCCCATTT
CGTTTGAACTCGGCCGTGGT

Product: peptide ABC transporter ATP-binding protein

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MPLLDIRNLTIELDTPHGRVKALEKVSLMLHAGEIHGLVGESGSGRSLLARAVLGIPGPNWTITADRMMWDGRNLMEMSD
VERRNLMGKDMAMIFQDPSGSLDPVITIGAQLIEAMPADKNVPFWRRGRERRLTAQKWLHKVGIKDPKRVMASYPWETSE
GECQKVMIAMALANQPRLLIADEPTNSMEPSTQAQIFRLLAQLNQLQGVTIMMISHELETLADWCNNLTVLYCGQVMESG
PIDELIREPLHPYTKALMDHLPDYRGNLPHKSLMPVLPGSAPALQHLPIGCRLGPRCPEARRECVHQPQLQHQKDRYYAC
HFPYRTETNNDDTAA

Sequences:

>Translated_335_residues
MPLLDIRNLTIELDTPHGRVKALEKVSLMLHAGEIHGLVGESGSGRSLLARAVLGIPGPNWTITADRMMWDGRNLMEMSD
VERRNLMGKDMAMIFQDPSGSLDPVITIGAQLIEAMPADKNVPFWRRGRERRLTAQKWLHKVGIKDPKRVMASYPWETSE
GECQKVMIAMALANQPRLLIADEPTNSMEPSTQAQIFRLLAQLNQLQGVTIMMISHELETLADWCNNLTVLYCGQVMESG
PIDELIREPLHPYTKALMDHLPDYRGNLPHKSLMPVLPGSAPALQHLPIGCRLGPRCPEARRECVHQPQLQHQKDRYYAC
HFPYRTETNNDDTAA
>Mature_334_residues
PLLDIRNLTIELDTPHGRVKALEKVSLMLHAGEIHGLVGESGSGRSLLARAVLGIPGPNWTITADRMMWDGRNLMEMSDV
ERRNLMGKDMAMIFQDPSGSLDPVITIGAQLIEAMPADKNVPFWRRGRERRLTAQKWLHKVGIKDPKRVMASYPWETSEG
ECQKVMIAMALANQPRLLIADEPTNSMEPSTQAQIFRLLAQLNQLQGVTIMMISHELETLADWCNNLTVLYCGQVMESGP
IDELIREPLHPYTKALMDHLPDYRGNLPHKSLMPVLPGSAPALQHLPIGCRLGPRCPEARRECVHQPQLQHQKDRYYACH
FPYRTETNNDDTAA

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4170

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787548, Length=328, Percent_Identity=56.0975609756098, Blast_Score=378, Evalue=1e-106,
Organism=Escherichia coli, GI1789963, Length=325, Percent_Identity=38.1538461538462, Blast_Score=234, Evalue=5e-63,
Organism=Escherichia coli, GI48994883, Length=324, Percent_Identity=37.037037037037, Blast_Score=207, Evalue=6e-55,
Organism=Escherichia coli, GI1787759, Length=325, Percent_Identity=36.3076923076923, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1787500, Length=328, Percent_Identity=35.3658536585366, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI145693107, Length=295, Percent_Identity=32.8813559322034, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1788506, Length=262, Percent_Identity=35.4961832061069, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1789962, Length=307, Percent_Identity=31.9218241042345, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1787758, Length=300, Percent_Identity=31, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1789890, Length=264, Percent_Identity=31.4393939393939, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI48994997, Length=257, Percent_Identity=32.6848249027237, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786398, Length=285, Percent_Identity=30.5263157894737, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789891, Length=249, Percent_Identity=30.5220883534137, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787547, Length=261, Percent_Identity=29.1187739463602, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789032, Length=238, Percent_Identity=29.8319327731092, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87081791, Length=270, Percent_Identity=26.6666666666667, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788225, Length=263, Percent_Identity=26.9961977186312, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1789873, Length=221, Percent_Identity=28.9592760180996, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI87081834, Length=217, Percent_Identity=30.4147465437788, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1786703, Length=221, Percent_Identity=32.579185520362, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1787029, Length=250, Percent_Identity=26.8, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788644, Length=248, Percent_Identity=29.0322580645161, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790544, Length=246, Percent_Identity=28.0487804878049, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787792, Length=240, Percent_Identity=28.75, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790525, Length=275, Percent_Identity=26.9090909090909, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787105, Length=221, Percent_Identity=28.0542986425339, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790162, Length=258, Percent_Identity=23.2558139534884, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789672, Length=248, Percent_Identity=24.5967741935484, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786563, Length=240, Percent_Identity=27.9166666666667, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790190, Length=250, Percent_Identity=25.6, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787712, Length=265, Percent_Identity=24.5283018867925, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87081782, Length=240, Percent_Identity=25.8333333333333, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787089, Length=262, Percent_Identity=26.3358778625954, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI87081709, Length=258, Percent_Identity=21.3178294573643, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788450, Length=244, Percent_Identity=24.1803278688525, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789586, Length=285, Percent_Identity=25.2631578947368, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786872, Length=212, Percent_Identity=26.8867924528302, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786345, Length=230, Percent_Identity=26.0869565217391, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786319, Length=229, Percent_Identity=24.8908296943231, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786803, Length=247, Percent_Identity=23.4817813765182, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1787370, Length=242, Percent_Identity=22.7272727272727, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790467, Length=243, Percent_Identity=22.2222222222222, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=239, Percent_Identity=28.8702928870293, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 37748; Mature: 37617

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDIRNLTIELDTPHGRVKALEKVSLMLHAGEIHGLVGESGSGRSLLARAVLGIPGPN
CCCCEEECEEEEEECCCHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHCCCCCC
WTITADRMMWDGRNLMEMSDVERRNLMGKDMAMIFQDPSGSLDPVITIGAQLIEAMPADK
EEEEECCEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCC
NVPFWRRGRERRLTAQKWLHKVGIKDPKRVMASYPWETSEGECQKVMIAMALANQPRLLI
CCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEE
ADEPTNSMEPSTQAQIFRLLAQLNQLQGVTIMMISHELETLADWCNNLTVLYCGQVMESG
EECCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHCCCEEEEECHHHCCC
PIDELIREPLHPYTKALMDHLPDYRGNLPHKSLMPVLPGSAPALQHLPIGCRLGPRCPEA
CHHHHHHCCCCHHHHHHHHHCCHHCCCCCCHHCCCCCCCCCCHHHHCCCCCCCCCCCHHH
RRECVHQPQLQHQKDRYYACHFPYRTETNNDDTAA
HHHHHCCCHHHHCCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
PLLDIRNLTIELDTPHGRVKALEKVSLMLHAGEIHGLVGESGSGRSLLARAVLGIPGPN
CCCEEECEEEEEECCCHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHCCCCCC
WTITADRMMWDGRNLMEMSDVERRNLMGKDMAMIFQDPSGSLDPVITIGAQLIEAMPADK
EEEEECCEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCC
NVPFWRRGRERRLTAQKWLHKVGIKDPKRVMASYPWETSEGECQKVMIAMALANQPRLLI
CCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEE
ADEPTNSMEPSTQAQIFRLLAQLNQLQGVTIMMISHELETLADWCNNLTVLYCGQVMESG
EECCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHCCCEEEEECHHHCCC
PIDELIREPLHPYTKALMDHLPDYRGNLPHKSLMPVLPGSAPALQHLPIGCRLGPRCPEA
CHHHHHHCCCCHHHHHHHHHCCHHCCCCCCHHCCCCCCCCCCHHHHCCCCCCCCCCCHHH
RRECVHQPQLQHQKDRYYACHFPYRTETNNDDTAA
HHHHHCCCHHHHCCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]