Click here to switch to the map view.

The map label for this gene is yeaP [H]

Identifier: 119774339

GI number: 119774339

Start: 1475050

End: 1476024

Strand: Reverse

Name: yeaP [H]

Synonym: Sama_1202

Alternate gene names: 119774339

Gene position: 1476024-1475050 (Counterclockwise)

Preceding gene: 119774340

Following gene: 119774337

Centisome position: 34.28

GC content: 50.05

Gene sequence:

>975_bases
ATGAGGGCCTACGGATATCACTCATTTCGTGACATACAGGTCAACGAAATTGACTGGCTGAGGTGGCAACGGCTTGTGGA
TACAGTCGCAGAGATGTTCCACGCACCCGCAGCCTTTATCAATCAGGCCAACACCAAAGGGATAGAGGTGCTGATAGCCT
CAGAACTCCCCACCACGCGTTATTCCCCAGGACATATCGCCACCATAGACCAAAACGTTTATAGCCACTATGTGGTGCAA
AAAAATCAGCTGCTGTATGTACCGGATGCAAGCCAGGATCCCCGTTGGCATGACAATCCGGAATTTCAGGACGATCACTA
TATCTCCTATCTGGGTATGCCCATCATCTGGCCCGACGGCGATACCTTTGGCACCCTGTGCGTATTATCCGATGTAGTCA
CCCAGTACCCTGCCACCTATTTAAAGGTGCTCAATGTCATTCGTGATGTCATCAACGCCGATTTGGCTCACATGTACCGA
GAAAACCAGCTCCTTAATCAAAGCTATCTTGACCCTCTGACCAAAATCTATAACCGCCGGGGCTTTGAAGAGTTGTTTGA
AAAGAACCAGCAGCTGGCACTGCGTCTGGGCCGTAAAATGGTATTGATCAGTTTTGATTTGGATGGCTTCAAACCCATCA
ATGATAATTATGGCCATATCACGGGAGACAAGATCCTGGCTTTTTTTGCAACCAGTCTGAAATCGAGCTGCCGGGGCAGT
GATTTGGTTGCCCGCTGGGGCGGTGATGAGTTTTTAGTGCTGGCCCACTCGGAAACCGAGCAGTTGGAGAACTCGGTATT
GCTAAGGCTGGATGAACACCTGGCCCACCAAAACCAGCTGCCTAAATTTGACTATTCCGTTGGTATGCTGCAACTGGACC
CGGCCACCCATTACGAACTCGACAGCTTACTGCCAAGCGTCGATGCCCGCATGTACCACCACAAGCGCACCAAACAGACA
AAACAACGCCAATAA

Upstream 100 bases:

>100_bases
AATTCGAAGCCAACGTCATCCCTAAGTTGCAACAACGTGTATCAGGCCTGCTCGGGCTGAACTAAACTTAATACTTGGAA
CAGACACACGGAGGTCACCG

Downstream 100 bases:

>100_bases
AAAAGCCCGGACTGTCCGGGCTTTTTCGTACGCTTTACCTTACTGGCAGCTTACGCCAACCGACGCAAAGGCGGCGGTCA
CATCAGACACTGCATAACCC

Product: GGDEF domain-containing protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MRAYGYHSFRDIQVNEIDWLRWQRLVDTVAEMFHAPAAFINQANTKGIEVLIASELPTTRYSPGHIATIDQNVYSHYVVQ
KNQLLYVPDASQDPRWHDNPEFQDDHYISYLGMPIIWPDGDTFGTLCVLSDVVTQYPATYLKVLNVIRDVINADLAHMYR
ENQLLNQSYLDPLTKIYNRRGFEELFEKNQQLALRLGRKMVLISFDLDGFKPINDNYGHITGDKILAFFATSLKSSCRGS
DLVARWGGDEFLVLAHSETEQLENSVLLRLDEHLAHQNQLPKFDYSVGMLQLDPATHYELDSLLPSVDARMYHHKRTKQT
KQRQ

Sequences:

>Translated_324_residues
MRAYGYHSFRDIQVNEIDWLRWQRLVDTVAEMFHAPAAFINQANTKGIEVLIASELPTTRYSPGHIATIDQNVYSHYVVQ
KNQLLYVPDASQDPRWHDNPEFQDDHYISYLGMPIIWPDGDTFGTLCVLSDVVTQYPATYLKVLNVIRDVINADLAHMYR
ENQLLNQSYLDPLTKIYNRRGFEELFEKNQQLALRLGRKMVLISFDLDGFKPINDNYGHITGDKILAFFATSLKSSCRGS
DLVARWGGDEFLVLAHSETEQLENSVLLRLDEHLAHQNQLPKFDYSVGMLQLDPATHYELDSLLPSVDARMYHHKRTKQT
KQRQ
>Mature_324_residues
MRAYGYHSFRDIQVNEIDWLRWQRLVDTVAEMFHAPAAFINQANTKGIEVLIASELPTTRYSPGHIATIDQNVYSHYVVQ
KNQLLYVPDASQDPRWHDNPEFQDDHYISYLGMPIIWPDGDTFGTLCVLSDVVTQYPATYLKVLNVIRDVINADLAHMYR
ENQLLNQSYLDPLTKIYNRRGFEELFEKNQQLALRLGRKMVLISFDLDGFKPINDNYGHITGDKILAFFATSLKSSCRGS
DLVARWGGDEFLVLAHSETEQLENSVLLRLDEHLAHQNQLPKFDYSVGMLQLDPATHYELDSLLPSVDARMYHHKRTKQT
KQRQ

Specific function: Catalyzes the condensation of two GTP molecules to the cyclic dinucleotide di-GMP (c-di-GMP), which acts as a secondary messenger (Probable). Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87081977, Length=245, Percent_Identity=32.2448979591837, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87081881, Length=198, Percent_Identity=32.3232323232323, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786584, Length=173, Percent_Identity=32.3699421965318, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082007, Length=213, Percent_Identity=30.0469483568075, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI87081974, Length=186, Percent_Identity=27.9569892473118, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI145693134, Length=160, Percent_Identity=32.5, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787802, Length=100, Percent_Identity=40, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787816, Length=168, Percent_Identity=29.1666666666667, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787056, Length=183, Percent_Identity=31.1475409836066, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788381, Length=157, Percent_Identity=31.2101910828025, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR003018 [H]

Pfam domain/function: PF01590 GAF; PF00990 GGDEF [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 37505; Mature: 37505

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAYGYHSFRDIQVNEIDWLRWQRLVDTVAEMFHAPAAFINQANTKGIEVLIASELPTTR
CCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEEECCCCCCC
YSPGHIATIDQNVYSHYVVQKNQLLYVPDASQDPRWHDNPEFQDDHYISYLGMPIIWPDG
CCCCEEEEECHHHHHHHEEECCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCEEECCCC
DTFGTLCVLSDVVTQYPATYLKVLNVIRDVINADLAHMYRENQLLNQSYLDPLTKIYNRR
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GFEELFEKNQQLALRLGRKMVLISFDLDGFKPINDNYGHITGDKILAFFATSLKSSCRGS
CHHHHHHCCHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
DLVARWGGDEFLVLAHSETEQLENSVLLRLDEHLAHQNQLPKFDYSVGMLQLDPATHYEL
CEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHH
DSLLPSVDARMYHHKRTKQTKQRQ
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRAYGYHSFRDIQVNEIDWLRWQRLVDTVAEMFHAPAAFINQANTKGIEVLIASELPTTR
CCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEEECCCCCCC
YSPGHIATIDQNVYSHYVVQKNQLLYVPDASQDPRWHDNPEFQDDHYISYLGMPIIWPDG
CCCCEEEEECHHHHHHHEEECCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCEEECCCC
DTFGTLCVLSDVVTQYPATYLKVLNVIRDVINADLAHMYRENQLLNQSYLDPLTKIYNRR
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GFEELFEKNQQLALRLGRKMVLISFDLDGFKPINDNYGHITGDKILAFFATSLKSSCRGS
CHHHHHHCCHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
DLVARWGGDEFLVLAHSETEQLENSVLLRLDEHLAHQNQLPKFDYSVGMLQLDPATHYEL
CEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHH
DSLLPSVDARMYHHKRTKQTKQRQ
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]