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The map label for this gene is ddc [H]

Identifier: 119774337

GI number: 119774337

Start: 1471185

End: 1472867

Strand: Reverse

Name: ddc [H]

Synonym: Sama_1200

Alternate gene names: 119774337

Gene position: 1472867-1471185 (Counterclockwise)

Preceding gene: 119774339

Following gene: 119774329

Centisome position: 34.2

GC content: 56.39

Gene sequence:

>1683_bases
ATGCCACCGGCGGTGCACAAGACAGCCAGACGTGATGAGATGACAGAAAAACACCTGCGCAAGGCCACAGCCTCTGAAGA
CAACCTGTTGCGGATCTTTACCGTACCGGAGGCGGCTGACTCTACCCTCGGCCGTATCGAGCAGCAGCTGTCTGCCGATC
TTGCCGGTTTCCTGCAGGACAATATTGCCGCGCTGGAACAACCTCTGTCAGATATTGAGGATCACTTCTACAGTGTCGAA
GTGCCACCACAACCCCAGTTTGTCTCCGATTACGTGGATGACATCATGGCTCATTTGGTGGCGCAGTCGGTACACACTGC
TGCGCCATCGTTTATCGGCCACATGACCTCTGCCCTGCCCTATTTCCTGTTGCCCCTGTCGAAACTGATGGTGGGGCTGA
ATCAGAATCTGGTGAAAATCGAAACCTCCAAGGCCTTTACCCCCATGGAGCGTCAGGTGCTGGGCATGATGCACCACCTG
ATTTATGGCCGCGAAAAGGATTTCTATCAGGGCTTCCTCCACAGCGCCAGCCATGCACTGGGGGCTTTTTGCTCCGGCGG
AACCGTTGCCAACATCACAGCGCTGTGGATTGCCCGCAACCAGTTACTGAAAGCCCGTGGTAACTTCAGGGGCGTGACCC
GTGAAGGCCTGCATAAGGCGCTCAAACATTATGGCTGGGATGATTTGGCGATTCTGGTGTCTGAACGTGGTCACTACTCC
CTCGGCAAAGCCGCAGATCTGCTTGGCATCGGCCGGGACAACATCATCAGCGTACCGGTGGATGCCCATAATAAGGTGGA
TATTGACGCCATGCGGGTTGCTGCAGCCCAATTACAGGCGCGCAATATCCGGGTAATGGCCATTGTCGGCGTCGCGGGCA
CCACAGAAACCGGCAATGTGGATCCTCTTGCTGAGATGGCAGCCCTTGCCAAAGAGATAGACTGCCATTTCCATGTGGAT
GCGGCCTGGGGCGGCGCTACCCTGCTGTCTGAAAAGTATCGTTATCTGCTCAGCGGTATCGAACTGGCGGATTCGGTCAC
CATAGATGCCCACAAGCAAATGTATGTGCCCATGGGCGCAGGTATGGTGCTGTTTAAAAATCCAAGCTTTGCCTCTGCCA
TCGAGCATCATGCCGAGTACATCCTGCGTCAGGGCTCCAAGGATCTGGGCAGCCAGACTCTGGAAGGTTCACGCCCCGGG
ATGGCGATGCTGGTTCATGCCTGTTTGAACATCATTGGCCGCGAAGGCTACGAAATCCTGATAAACGGCTCGCTGGAGCG
CGCCCGATTTTTTGCGGGGCTCATTGAGGCCCAAACGGATTTTGAGCTTATCAGCGAACCGGAGCTGTGCCTGCTGACCT
ACAGATACGTGCCTGCAAAGGTGCGCCTGGCACTGGCACAGGCAGTAGCGCAGCACGACAAAGATAAACTCGATGCCATT
GGCAGTCTGCTTGACGATCTCACCCGCGCCATTCAGAAAACCCAGCGCGAGCAGGGTAAATCCTTTGTCTCCCGCACCCG
TATCACGCCCAAGCGCTATGGTAACGACAAGCGCACCGTGTTCAGGGTTGTGCTGGCCAATCCCCTCACAACCGAGGCCA
TACTGGCCGCGGTGCTGGAAGAGCAACGAGCGCTGGCAAGCGGGGAAACTGAGATACTGCAGGCCCTCGACGCTCTGTGT
TGA

Upstream 100 bases:

>100_bases
GGGCAAGTCACTTTTGGGCTGCTATCCACAAGCCGTTGTTGCATACCCTTGATGCAAACCAGACCTTGCAGTAAAGTGAG
CTCCCTTTTCGCCGCCGGGC

Downstream 100 bases:

>100_bases
AATGGCGCTGTGTTGAAATGGCACTGTGTTGAAATCGCGCTGTGCTGACATGGCCCAGCACAGCACTCAAAGAAGCACGC
AACAAACAATAAAGCCCGGC

Product: pyridoxal-dependent decarboxylase

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 560; Mature: 559

Protein sequence:

>560_residues
MPPAVHKTARRDEMTEKHLRKATASEDNLLRIFTVPEAADSTLGRIEQQLSADLAGFLQDNIAALEQPLSDIEDHFYSVE
VPPQPQFVSDYVDDIMAHLVAQSVHTAAPSFIGHMTSALPYFLLPLSKLMVGLNQNLVKIETSKAFTPMERQVLGMMHHL
IYGREKDFYQGFLHSASHALGAFCSGGTVANITALWIARNQLLKARGNFRGVTREGLHKALKHYGWDDLAILVSERGHYS
LGKAADLLGIGRDNIISVPVDAHNKVDIDAMRVAAAQLQARNIRVMAIVGVAGTTETGNVDPLAEMAALAKEIDCHFHVD
AAWGGATLLSEKYRYLLSGIELADSVTIDAHKQMYVPMGAGMVLFKNPSFASAIEHHAEYILRQGSKDLGSQTLEGSRPG
MAMLVHACLNIIGREGYEILINGSLERARFFAGLIEAQTDFELISEPELCLLTYRYVPAKVRLALAQAVAQHDKDKLDAI
GSLLDDLTRAIQKTQREQGKSFVSRTRITPKRYGNDKRTVFRVVLANPLTTEAILAAVLEEQRALASGETEILQALDALC

Sequences:

>Translated_560_residues
MPPAVHKTARRDEMTEKHLRKATASEDNLLRIFTVPEAADSTLGRIEQQLSADLAGFLQDNIAALEQPLSDIEDHFYSVE
VPPQPQFVSDYVDDIMAHLVAQSVHTAAPSFIGHMTSALPYFLLPLSKLMVGLNQNLVKIETSKAFTPMERQVLGMMHHL
IYGREKDFYQGFLHSASHALGAFCSGGTVANITALWIARNQLLKARGNFRGVTREGLHKALKHYGWDDLAILVSERGHYS
LGKAADLLGIGRDNIISVPVDAHNKVDIDAMRVAAAQLQARNIRVMAIVGVAGTTETGNVDPLAEMAALAKEIDCHFHVD
AAWGGATLLSEKYRYLLSGIELADSVTIDAHKQMYVPMGAGMVLFKNPSFASAIEHHAEYILRQGSKDLGSQTLEGSRPG
MAMLVHACLNIIGREGYEILINGSLERARFFAGLIEAQTDFELISEPELCLLTYRYVPAKVRLALAQAVAQHDKDKLDAI
GSLLDDLTRAIQKTQREQGKSFVSRTRITPKRYGNDKRTVFRVVLANPLTTEAILAAVLEEQRALASGETEILQALDALC
>Mature_559_residues
PPAVHKTARRDEMTEKHLRKATASEDNLLRIFTVPEAADSTLGRIEQQLSADLAGFLQDNIAALEQPLSDIEDHFYSVEV
PPQPQFVSDYVDDIMAHLVAQSVHTAAPSFIGHMTSALPYFLLPLSKLMVGLNQNLVKIETSKAFTPMERQVLGMMHHLI
YGREKDFYQGFLHSASHALGAFCSGGTVANITALWIARNQLLKARGNFRGVTREGLHKALKHYGWDDLAILVSERGHYSL
GKAADLLGIGRDNIISVPVDAHNKVDIDAMRVAAAQLQARNIRVMAIVGVAGTTETGNVDPLAEMAALAKEIDCHFHVDA
AWGGATLLSEKYRYLLSGIELADSVTIDAHKQMYVPMGAGMVLFKNPSFASAIEHHAEYILRQGSKDLGSQTLEGSRPGM
AMLVHACLNIIGREGYEILINGSLERARFFAGLIEAQTDFELISEPELCLLTYRYVPAKVRLALAQAVAQHDKDKLDAIG
SLLDDLTRAIQKTQREQGKSFVSRTRITPKRYGNDKRTVFRVVLANPLTTEAILAAVLEEQRALASGETEILQALDALC

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI197276620, Length=503, Percent_Identity=25.4473161033797, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI4503875, Length=503, Percent_Identity=25.4473161033797, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI58331246, Length=476, Percent_Identity=26.4705882352941, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI197383062, Length=406, Percent_Identity=27.5862068965517, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI194294551, Length=371, Percent_Identity=26.9541778975741, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI4503281, Length=402, Percent_Identity=21.8905472636816, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI132814448, Length=402, Percent_Identity=21.8905472636816, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI31982936, Length=231, Percent_Identity=27.7056277056277, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17555682, Length=476, Percent_Identity=26.890756302521, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI71993062, Length=451, Percent_Identity=27.7161862527716, Blast_Score=155, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI71993058, Length=377, Percent_Identity=27.8514588859416, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17543922, Length=296, Percent_Identity=26.6891891891892, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17557272, Length=298, Percent_Identity=26.1744966442953, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17136594, Length=464, Percent_Identity=26.5086206896552, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24657193, Length=473, Percent_Identity=25.369978858351, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24657185, Length=473, Percent_Identity=25.369978858351, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24657188, Length=473, Percent_Identity=25.369978858351, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI21356415, Length=471, Percent_Identity=23.5668789808917, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24585139, Length=243, Percent_Identity=28.3950617283951, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221476190, Length=243, Percent_Identity=28.3950617283951, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24585143, Length=243, Percent_Identity=28.3950617283951, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 61510; Mature: 61379

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPAVHKTARRDEMTEKHLRKATASEDNLLRIFTVPEAADSTLGRIEQQLSADLAGFLQD
CCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
NIAALEQPLSDIEDHFYSVEVPPQPQFVSDYVDDIMAHLVAQSVHTAAPSFIGHMTSALP
HHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFLLPLSKLMVGLNQNLVKIETSKAFTPMERQVLGMMHHLIYGREKDFYQGFLHSASHAL
HHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
GAFCSGGTVANITALWIARNQLLKARGNFRGVTREGLHKALKHYGWDDLAILVSERGHYS
HHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCC
LGKAADLLGIGRDNIISVPVDAHNKVDIDAMRVAAAQLQARNIRVMAIVGVAGTTETGNV
CCCHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCC
DPLAEMAALAKEIDCHFHVDAAWGGATLLSEKYRYLLSGIELADSVTIDAHKQMYVPMGA
CHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCC
GMVLFKNPSFASAIEHHAEYILRQGSKDLGSQTLEGSRPGMAMLVHACLNIIGREGYEIL
CEEEEECCCHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
INGSLERARFFAGLIEAQTDFELISEPELCLLTYRYVPAKVRLALAQAVAQHDKDKLDAI
EECCHHHHHHHHHHHHCCCCHHHHCCCCEEEEEEHHCCHHHHHHHHHHHHHCCHHHHHHH
GSLLDDLTRAIQKTQREQGKSFVSRTRITPKRYGNDKRTVFRVVLANPLTTEAILAAVLE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHH
EQRALASGETEILQALDALC
HHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
PPAVHKTARRDEMTEKHLRKATASEDNLLRIFTVPEAADSTLGRIEQQLSADLAGFLQD
CCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
NIAALEQPLSDIEDHFYSVEVPPQPQFVSDYVDDIMAHLVAQSVHTAAPSFIGHMTSALP
HHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFLLPLSKLMVGLNQNLVKIETSKAFTPMERQVLGMMHHLIYGREKDFYQGFLHSASHAL
HHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
GAFCSGGTVANITALWIARNQLLKARGNFRGVTREGLHKALKHYGWDDLAILVSERGHYS
HHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCC
LGKAADLLGIGRDNIISVPVDAHNKVDIDAMRVAAAQLQARNIRVMAIVGVAGTTETGNV
CCCHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCC
DPLAEMAALAKEIDCHFHVDAAWGGATLLSEKYRYLLSGIELADSVTIDAHKQMYVPMGA
CHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCC
GMVLFKNPSFASAIEHHAEYILRQGSKDLGSQTLEGSRPGMAMLVHACLNIIGREGYEIL
CEEEEECCCHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
INGSLERARFFAGLIEAQTDFELISEPELCLLTYRYVPAKVRLALAQAVAQHDKDKLDAI
EECCHHHHHHHHHHHHCCCCHHHHCCCCEEEEEEHHCCHHHHHHHHHHHHHCCHHHHHHH
GSLLDDLTRAIQKTQREQGKSFVSRTRITPKRYGNDKRTVFRVVLANPLTTEAILAAVLE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHH
EQRALASGETEILQALDALC
HHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8772175 [H]