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The map label for this gene is pyrH [H]

Identifier: 119774278

GI number: 119774278

Start: 1391076

End: 1391801

Strand: Direct

Name: pyrH [H]

Synonym: Sama_1141

Alternate gene names: 119774278

Gene position: 1391076-1391801 (Clockwise)

Preceding gene: 119774277

Following gene: 119774279

Centisome position: 32.3

GC content: 51.79

Gene sequence:

>726_bases
ATGAGCACCAATCCAAAACCAGCATTTCGACGCATTCTTCTTAAGTTAAGTGGTGAGGCCCTGATGGGCTCTGAGGGCTT
CGGTATTGATCCCAGCGTACTGGATCGTATGGCTCAGGAAATCAAAGAACTGGTAGAACTGGGCATCCAGGTCGGGGTAG
TGATTGGTGGTGGTAACCTGTTCCGTGGAGAAGGTCTTGCCAAGGCAGGTATGAACCGCGTGGTGGGTGACCACATGGGT
ATGCTGGCGACCGTGATGAATGGTCTGGCAATGCGCGATGCCTTGCACCGTGCCTATGTGAATGCCCGTCTGATGTCTGC
CATTCCCTTGAAAGGGGTGTGTGACGATTATAATTGGGCCGAGGCTATCAGCCTGCTCAAGTCCGGACGTGTGGTGATAT
TCGCTGCCGGTACCGGTAATCCTTTCTGCACCACCGACTCGGCGGCCTGTCTGCGCGGCATTGAAATTGAAGCCGATGTC
GTGCTAAAAGGCACCAAAGTTGATGGCGTTTACTCCGCCGATCCTATGAAGGACCCGGAAGCCGTCAAATACGATGAACT
CTCTTACGCCGAAGTTCTCGATAAAGAATTGAAAGTGATGGACTTATCTGCCTTTACCATGGCGCGTGACCATGATATGC
CTATTTTGGTATTCAACATGAACAAGCCCGGTGCCCTGCGCCGTGTTATCATGGGTGAAGGTGAAGGCACCATCATCAAA
AAATAA

Upstream 100 bases:

>100_bases
CCAAGCAAATCGCTGCTTCTCAAAAGGCCTAATCGCCGCTAGGTAAGTACCCCAAGACCGCAGCAGCCGCTGCGGTCTTG
TTATAATCAGGATAAAAATC

Downstream 100 bases:

>100_bases
GCGACAAGTTTGCGAACATTAATGACCGAAAAGGACATTTAACGTGATTGAAGATATCAAGAAAGATGCTCAGGATCGCA
TGGGCAAGTGTGTAGAGGCC

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MSTNPKPAFRRILLKLSGEALMGSEGFGIDPSVLDRMAQEIKELVELGIQVGVVIGGGNLFRGEGLAKAGMNRVVGDHMG
MLATVMNGLAMRDALHRAYVNARLMSAIPLKGVCDDYNWAEAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEADV
VLKGTKVDGVYSADPMKDPEAVKYDELSYAEVLDKELKVMDLSAFTMARDHDMPILVFNMNKPGALRRVIMGEGEGTIIK
K

Sequences:

>Translated_241_residues
MSTNPKPAFRRILLKLSGEALMGSEGFGIDPSVLDRMAQEIKELVELGIQVGVVIGGGNLFRGEGLAKAGMNRVVGDHMG
MLATVMNGLAMRDALHRAYVNARLMSAIPLKGVCDDYNWAEAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEADV
VLKGTKVDGVYSADPMKDPEAVKYDELSYAEVLDKELKVMDLSAFTMARDHDMPILVFNMNKPGALRRVIMGEGEGTIIK
K
>Mature_240_residues
STNPKPAFRRILLKLSGEALMGSEGFGIDPSVLDRMAQEIKELVELGIQVGVVIGGGNLFRGEGLAKAGMNRVVGDHMGM
LATVMNGLAMRDALHRAYVNARLMSAIPLKGVCDDYNWAEAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEADVV
LKGTKVDGVYSADPMKDPEAVKYDELSYAEVLDKELKVMDLSAFTMARDHDMPILVFNMNKPGALRRVIMGEGEGTIIKK

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=241, Percent_Identity=82.9875518672199, Blast_Score=419, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25966; Mature: 25835

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNPKPAFRRILLKLSGEALMGSEGFGIDPSVLDRMAQEIKELVELGIQVGVVIGGGNL
CCCCCCHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCE
FRGEGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLKGVCDDYNWA
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
EAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEADVVLKGTKVDGVYSADPMKDPE
HHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHCCEEEEEEEEECCEECCEECCCCCCCCC
AVKYDELSYAEVLDKELKVMDLSAFTMARDHDMPILVFNMNKPGALRRVIMGEGEGTIIK
CCCCCCCHHHHHHHHHHHEEEHHHHHHHCCCCCEEEEEECCCCCHHHHEEEECCCCEEEC
K
C
>Mature Secondary Structure 
STNPKPAFRRILLKLSGEALMGSEGFGIDPSVLDRMAQEIKELVELGIQVGVVIGGGNL
CCCCCHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCE
FRGEGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLKGVCDDYNWA
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
EAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEADVVLKGTKVDGVYSADPMKDPE
HHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHCCEEEEEEEEECCEECCEECCCCCCCCC
AVKYDELSYAEVLDKELKVMDLSAFTMARDHDMPILVFNMNKPGALRRVIMGEGEGTIIK
CCCCCCCHHHHHHHHHHHEEEHHHHHHHCCCCCEEEEEECCCCCHHHHEEEECCCCEEEC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA