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The map label for this gene is frr

Identifier: 119774279

GI number: 119774279

Start: 1391845

End: 1392402

Strand: Direct

Name: frr

Synonym: Sama_1142

Alternate gene names: 119774279

Gene position: 1391845-1392402 (Clockwise)

Preceding gene: 119774278

Following gene: 119774280

Centisome position: 32.32

GC content: 53.05

Gene sequence:

>558_bases
GTGATTGAAGATATCAAGAAAGATGCTCAGGATCGCATGGGCAAGTGTGTAGAGGCCACCAAGGCCCAAATGGCTAAAGT
ACGTACTGGCCGTGCCCACCCAAGTCTGCTGGATACCATTCAGGTAAACTACTACGGTTCCATGACGCCTCTGAAGCAAG
TGGGTAACGTGACCATTGAAGACTCACGCACCCTGGCGGTGAACGTGTTTGACCGCAGTGCCATCCAGGCCGTAGAGAAA
GCTATCATGAGCTCAGACCTGGGTCTGAACCCAATGTCTGCCGGTGCGACTATCCGTATTCCGCTGCCACCACTGACTGA
AGAGCGTCGTCGTGACCTGGTTAAAGTAGTTCGCGCCGAAGCCGAGCAGGGCCGTGTAGCCATTCGTAACGTACGCCGCG
ATGCCAACTCCAGCTTCAAGCAGCTGGAAAAAGAGAAAGAGTGCACCGAAGACGACGTACGTCGTTCCGAAGAAGAAGTT
CAGAAAATCACCGATCTGCACATTAAGAAGATCGATGAGCTCCTGGCTGCCAAAGAAGCGGAGTTGATGGAGGTCTAA

Upstream 100 bases:

>100_bases
GGTGCCCTGCGCCGTGTTATCATGGGTGAAGGTGAAGGCACCATCATCAAAAAATAAGCGACAAGTTTGCGAACATTAAT
GACCGAAAAGGACATTTAAC

Downstream 100 bases:

>100_bases
CCCTCCGGTCAGCAAGCTAGAGTTAAGACGCCGTGTAGGGGTATACTACACGGCGTTTGTTTATTTATAGGGTTGTATAT
CGATGTCTTCCAATAGGGAA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIEDIKKDAQDRMGKCVEATKAQMAKVRTGRAHPSLLDTIQVNYYGSMTPLKQVGNVTIEDSRTLAVNVFDRSAIQAVEK
AIMSSDLGLNPMSAGATIRIPLPPLTEERRRDLVKVVRAEAEQGRVAIRNVRRDANSSFKQLEKEKECTEDDVRRSEEEV
QKITDLHIKKIDELLAAKEAELMEV

Sequences:

>Translated_185_residues
MIEDIKKDAQDRMGKCVEATKAQMAKVRTGRAHPSLLDTIQVNYYGSMTPLKQVGNVTIEDSRTLAVNVFDRSAIQAVEK
AIMSSDLGLNPMSAGATIRIPLPPLTEERRRDLVKVVRAEAEQGRVAIRNVRRDANSSFKQLEKEKECTEDDVRRSEEEV
QKITDLHIKKIDELLAAKEAELMEV
>Mature_185_residues
MIEDIKKDAQDRMGKCVEATKAQMAKVRTGRAHPSLLDTIQVNYYGSMTPLKQVGNVTIEDSRTLAVNVFDRSAIQAVEK
AIMSSDLGLNPMSAGATIRIPLPPLTEERRRDLVKVVRAEAEQGRVAIRNVRRDANSSFKQLEKEKECTEDDVRRSEEEV
QKITDLHIKKIDELLAAKEAELMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=188, Percent_Identity=29.7872340425532, Blast_Score=77, Evalue=6e-15,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=30.6666666666667, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=68.6486486486486, Blast_Score=259, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=31.7919075144509, Blast_Score=81, Evalue=5e-16,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_SHEAM (A1S4P3)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927019.1
- ProteinModelPortal:   A1S4P3
- SMR:   A1S4P3
- STRING:   A1S4P3
- GeneID:   4603394
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1142
- NMPDR:   fig|326297.7.peg.1074
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   A1S4P3
- ProtClustDB:   PRK00083
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20790; Mature: 20790

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEDIKKDAQDRMGKCVEATKAQMAKVRTGRAHPSLLDTIQVNYYGSMTPLKQVGNVTIE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEECCCCCCCHHHHHCCEEEE
DSRTLAVNVFDRSAIQAVEKAIMSSDLGLNPMSAGATIRIPLPPLTEERRRDLVKVVRAE
CCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
AEQGRVAIRNVRRDANSSFKQLEKEKECTEDDVRRSEEEVQKITDLHIKKIDELLAAKEA
HHCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC
>Mature Secondary Structure
MIEDIKKDAQDRMGKCVEATKAQMAKVRTGRAHPSLLDTIQVNYYGSMTPLKQVGNVTIE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEECCCCCCCHHHHHCCEEEE
DSRTLAVNVFDRSAIQAVEKAIMSSDLGLNPMSAGATIRIPLPPLTEERRRDLVKVVRAE
CCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
AEQGRVAIRNVRRDANSSFKQLEKEKECTEDDVRRSEEEVQKITDLHIKKIDELLAAKEA
HHCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA