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The map label for this gene is fusA [C]

Identifier: 119774255

GI number: 119774255

Start: 1368423

End: 1370471

Strand: Direct

Name: fusA [C]

Synonym: Sama_1118

Alternate gene names: 119774255

Gene position: 1368423-1370471 (Clockwise)

Preceding gene: 119774254

Following gene: 119774256

Centisome position: 31.78

GC content: 55.3

Gene sequence:

>2049_bases
ATGGCTGAGTACCAGACCGCGAGGATCCGCAACTTTGCCTTGCTTGGGCATACCGGAGCGGGTAAGTCCTCGCTGCTTGA
GGCACTGCTTTATGGTGCCAGGGTAATAAACCAGCGGGGCAGGGTGGATAAGGGCACAAATCATGCCGATTTCACTGCCC
AGGAAAAAGCCCACCAACATAGTCTCGAACCATCCTTCCTCAATCTAGATTTCGACGAACACCACATCAACCTTATTGAT
ACCCCCGGATTACCCGACTTTTTCGGACGCGCGCTCTTACCTTTGCCAGCGGTAGAATCTGTACTCTTGGTGGTGAATGC
CGCCACAGGGATAGAGCCGGTTACTGCCCGAGCGTTTGAAGCTGCCCGGGCACAGGGCAAAGTGGTGTGTATTTGTGTGA
ACCACATCGATGGGCATTTGGATAAGCTGCCCGCCATTATTGAAGAGCTGCAAACCACCTTCGGCCCCCGCTGTCTGCCG
GTTAATCTGCCGTCTGCCGATGGAAACGATGTGGTTGACTGCTATTTGCACTGCGAAGATACCCGCCCCACGCTTTTTTC
CCAGGCCGCCTCGGCGCGGGATGAGCTGGTGGACACAGTGCTGGAAGAAGATGAAGCCCTGATGACCCTGTATTTGGAGC
AGGGTGAAATGCTCAGTGCCGAGCAGCTCCATGAGCCTTTGGAAACGGCACTCAGAATGGGGCATCTGGTGCCTATTTGC
TTTACCAGTGCAGAGCTTGATATCGGCATCGCCTCCTTGCTTGAAATCATGGTTAAGCTGATGCCCAGTCCGCTGGAGGC
CAATCCGCCGCAGTTTATCAAAGGTTTCGGTGACAAGGCCGTGCCGGTTGATGTGACCCAAAGCCCGGATGACCATGTGC
TGGCACAGGTGTTCAGGGTGGGCATAGACCCCTATTTTGGTCGGGTGGCTGTGTTCCGTTTGTATCAGGGCACGCTGGAA
GCGGGTATGCGGCTTTTTATTGGTGCCGACCGCAAGCCAGTGAAAGTGGCCCACCTTATCAAGCTTCAGGGCGCCGAAAC
CACGGAGGTAGAAAAGGCCATTCCCGGCGATATCTGCGCGCTTTGCAAAATTGATGAGCTGGAAGTGGGTTCGGTTTTGC
ACGACAGCCACGATGAAGACGAGTTCCATCTGCGGGAGCTGAAAATGCCCCAGCCGATTTTTGGTTTGGCGGTATCGCCC
AAACGCCGTGGCGATGAGCAGAAAATTGCCGAGGTGCTGGCCAAACTGATAGCCGAAGATCCCAGCCTAGCGGTGTCGCA
AAATGATGCGGAAGGCCAGACAGTGCTGAGCGGTCTTGGGGATCTGCATTTGCAGATTGCACTGGAAAAGGCCCAGAGCG
TGTTCAGGGTGGATATGGAAACCTGCAAGCCAGCGGTGGCTTATCGGGAAACCGTGTGTAAGGCAGCAACGGCCCGTTAT
CGTCACAAGAAGCAGTCCGGTGGCGCCGGGCAATTTGGCGAAGTGGAGCTGACCGTTGAGCCTTTACCAAGGGGACAAGG
ATTTGAATTTGTCTCCAAAGTAGTTGGCGGCGCCGTGCCCACCCAGTTTATTCCTGCGGTGGAAAAAGGTGTGCGTGAAG
CGCTCAAGGTTGGGCGACTTGGCGGTTATCCGGTGGAAGATGTGCGCGTTACCGTGCTCGATGGTAAGCACCACAGCGTT
GACTCCAAGGAGATTGCCTTTGTGATGGCCGGTAAAAAAGCCTTCTATGAAGCCTTTTTGCAGGCAAACCCGGTGATTTT
GGAGCCGCTGGTGTCGATGGAGATTCTGGTGAGTGCCGAGGATGTGGGTGATATAACCGGGCATCTCAGTTCCAGCCGCG
CCATGGTTTGCGGTACCGAAGCCCGACGTGATGGCAAGGTAAAGGTATTGGCCGAAGCGCCGCTGTCCACCGTGGATGAC
TACGCGACCCGGCTTAAGTCCATGACTTCGGGCGAAGGTGAATTCACCTTAAGCTTTGCCCGCTATGAGGTTGTTCCCCC
AGCGGTGCAGCAAAGCCTGCTGCGTACCATAGAGGATAAAGACGACTAA

Upstream 100 bases:

>100_bases
GCCCGGCTGGTTGGTCTTGTGACCTCAGTCAAATCCTGTGTTCATTCTCAGAACTATACTGCTTTTGTAGCCAAGTAGAA
TGTGACACAAGGAGGCCGTT

Downstream 100 bases:

>100_bases
ATGTAACCTGTTTGCCAGCAGTTTACAGACATCTCTCCCAAACCTTTGCGGCGCTTTGTGGACCTCCCCCGGCGCCGCTT
TTTTATGTCTTCGGTTTGCG

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 682; Mature: 681

Protein sequence:

>682_residues
MAEYQTARIRNFALLGHTGAGKSSLLEALLYGARVINQRGRVDKGTNHADFTAQEKAHQHSLEPSFLNLDFDEHHINLID
TPGLPDFFGRALLPLPAVESVLLVVNAATGIEPVTARAFEAARAQGKVVCICVNHIDGHLDKLPAIIEELQTTFGPRCLP
VNLPSADGNDVVDCYLHCEDTRPTLFSQAASARDELVDTVLEEDEALMTLYLEQGEMLSAEQLHEPLETALRMGHLVPIC
FTSAELDIGIASLLEIMVKLMPSPLEANPPQFIKGFGDKAVPVDVTQSPDDHVLAQVFRVGIDPYFGRVAVFRLYQGTLE
AGMRLFIGADRKPVKVAHLIKLQGAETTEVEKAIPGDICALCKIDELEVGSVLHDSHDEDEFHLRELKMPQPIFGLAVSP
KRRGDEQKIAEVLAKLIAEDPSLAVSQNDAEGQTVLSGLGDLHLQIALEKAQSVFRVDMETCKPAVAYRETVCKAATARY
RHKKQSGGAGQFGEVELTVEPLPRGQGFEFVSKVVGGAVPTQFIPAVEKGVREALKVGRLGGYPVEDVRVTVLDGKHHSV
DSKEIAFVMAGKKAFYEAFLQANPVILEPLVSMEILVSAEDVGDITGHLSSSRAMVCGTEARRDGKVKVLAEAPLSTVDD
YATRLKSMTSGEGEFTLSFARYEVVPPAVQQSLLRTIEDKDD

Sequences:

>Translated_682_residues
MAEYQTARIRNFALLGHTGAGKSSLLEALLYGARVINQRGRVDKGTNHADFTAQEKAHQHSLEPSFLNLDFDEHHINLID
TPGLPDFFGRALLPLPAVESVLLVVNAATGIEPVTARAFEAARAQGKVVCICVNHIDGHLDKLPAIIEELQTTFGPRCLP
VNLPSADGNDVVDCYLHCEDTRPTLFSQAASARDELVDTVLEEDEALMTLYLEQGEMLSAEQLHEPLETALRMGHLVPIC
FTSAELDIGIASLLEIMVKLMPSPLEANPPQFIKGFGDKAVPVDVTQSPDDHVLAQVFRVGIDPYFGRVAVFRLYQGTLE
AGMRLFIGADRKPVKVAHLIKLQGAETTEVEKAIPGDICALCKIDELEVGSVLHDSHDEDEFHLRELKMPQPIFGLAVSP
KRRGDEQKIAEVLAKLIAEDPSLAVSQNDAEGQTVLSGLGDLHLQIALEKAQSVFRVDMETCKPAVAYRETVCKAATARY
RHKKQSGGAGQFGEVELTVEPLPRGQGFEFVSKVVGGAVPTQFIPAVEKGVREALKVGRLGGYPVEDVRVTVLDGKHHSV
DSKEIAFVMAGKKAFYEAFLQANPVILEPLVSMEILVSAEDVGDITGHLSSSRAMVCGTEARRDGKVKVLAEAPLSTVDD
YATRLKSMTSGEGEFTLSFARYEVVPPAVQQSLLRTIEDKDD
>Mature_681_residues
AEYQTARIRNFALLGHTGAGKSSLLEALLYGARVINQRGRVDKGTNHADFTAQEKAHQHSLEPSFLNLDFDEHHINLIDT
PGLPDFFGRALLPLPAVESVLLVVNAATGIEPVTARAFEAARAQGKVVCICVNHIDGHLDKLPAIIEELQTTFGPRCLPV
NLPSADGNDVVDCYLHCEDTRPTLFSQAASARDELVDTVLEEDEALMTLYLEQGEMLSAEQLHEPLETALRMGHLVPICF
TSAELDIGIASLLEIMVKLMPSPLEANPPQFIKGFGDKAVPVDVTQSPDDHVLAQVFRVGIDPYFGRVAVFRLYQGTLEA
GMRLFIGADRKPVKVAHLIKLQGAETTEVEKAIPGDICALCKIDELEVGSVLHDSHDEDEFHLRELKMPQPIFGLAVSPK
RRGDEQKIAEVLAKLIAEDPSLAVSQNDAEGQTVLSGLGDLHLQIALEKAQSVFRVDMETCKPAVAYRETVCKAATARYR
HKKQSGGAGQFGEVELTVEPLPRGQGFEFVSKVVGGAVPTQFIPAVEKGVREALKVGRLGGYPVEDVRVTVLDGKHHSVD
SKEIAFVMAGKKAFYEAFLQANPVILEPLVSMEILVSAEDVGDITGHLSSSRAMVCGTEARRDGKVKVLAEAPLSTVDDY
ATRLKSMTSGEGEFTLSFARYEVVPPAVQQSLLRTIEDKDD

Specific function: This Protein Promotes The GTP-Dependent Translocation Of The Nascent Protein Chain From The A-Site To The P-Site Of The Ribosome. [C]

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=694, Percent_Identity=27.3775216138329, Blast_Score=269, Evalue=5e-72,
Organism=Homo sapiens, GI19923640, Length=722, Percent_Identity=24.0997229916898, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI25306287, Length=307, Percent_Identity=27.0358306188925, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI25306283, Length=443, Percent_Identity=22.3476297968397, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1789738, Length=699, Percent_Identity=29.8998569384835, Blast_Score=346, Evalue=3e-96,
Organism=Escherichia coli, GI1790835, Length=501, Percent_Identity=24.3512974051896, Blast_Score=114, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17533571, Length=685, Percent_Identity=29.6350364963504, Blast_Score=298, Evalue=8e-81,
Organism=Caenorhabditis elegans, GI17556745, Length=401, Percent_Identity=21.4463840399002, Blast_Score=85, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323098, Length=706, Percent_Identity=28.4702549575071, Blast_Score=278, Evalue=2e-75,
Organism=Saccharomyces cerevisiae, GI6322359, Length=788, Percent_Identity=23.4771573604061, Blast_Score=205, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6324707, Length=480, Percent_Identity=22.7083333333333, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320593, Length=480, Percent_Identity=22.7083333333333, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24582462, Length=710, Percent_Identity=28.8732394366197, Blast_Score=294, Evalue=1e-79,
Organism=Drosophila melanogaster, GI221458488, Length=710, Percent_Identity=24.2253521126761, Blast_Score=171, Evalue=1e-42,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 74242; Mature: 74110

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEYQTARIRNFALLGHTGAGKSSLLEALLYGARVINQRGRVDKGTNHADFTAQEKAHQH
CCCCCHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
SLEPSFLNLDFDEHHINLIDTPGLPDFFGRALLPLPAVESVLLVVNAATGIEPVTARAFE
CCCCCEEECCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHEEECCCCCCHHHHHHHH
AARAQGKVVCICVNHIDGHLDKLPAIIEELQTTFGPRCLPVNLPSADGNDVVDCYLHCED
HHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEEEEECC
TRPTLFSQAASARDELVDTVLEEDEALMTLYLEQGEMLSAEQLHEPLETALRMGHLVPIC
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEE
FTSAELDIGIASLLEIMVKLMPSPLEANPPQFIKGFGDKAVPVDVTQSPDDHVLAQVFRV
EECCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCEEECCCCCCHHHHHHHHHH
GIDPYFGRVAVFRLYQGTLEAGMRLFIGADRKPVKVAHLIKLQGAETTEVEKAIPGDICA
CCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEEECCCCCHHHHHCCCCCEEE
LCKIDELEVGSVLHDSHDEDEFHLRELKMPQPIFGLAVSPKRRGDEQKIAEVLAKLIAED
HEECCCCCCCHHHCCCCCCCHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCC
PSLAVSQNDAEGQTVLSGLGDLHLQIALEKAQSVFRVDMETCKPAVAYRETVCKAATARY
CCEEEECCCCCHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RHKKQSGGAGQFGEVELTVEPLPRGQGFEFVSKVVGGAVPTQFIPAVEKGVREALKVGRL
HHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
GGYPVEDVRVTVLDGKHHSVDSKEIAFVMAGKKAFYEAFLQANPVILEPLVSMEILVSAE
CCCCCCCEEEEEECCCCCCCCCCEEEEEEECHHHHHHHHHHCCCEEEHHHHCEEEEEECH
DVGDITGHLSSSRAMVCGTEARRDGKVKVLAEAPLSTVDDYATRLKSMTSGEGEFTLSFA
HHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEE
RYEVVPPAVQQSLLRTIEDKDD
EEECCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AEYQTARIRNFALLGHTGAGKSSLLEALLYGARVINQRGRVDKGTNHADFTAQEKAHQH
CCCCHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
SLEPSFLNLDFDEHHINLIDTPGLPDFFGRALLPLPAVESVLLVVNAATGIEPVTARAFE
CCCCCEEECCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHEEECCCCCCHHHHHHHH
AARAQGKVVCICVNHIDGHLDKLPAIIEELQTTFGPRCLPVNLPSADGNDVVDCYLHCED
HHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEEEEECC
TRPTLFSQAASARDELVDTVLEEDEALMTLYLEQGEMLSAEQLHEPLETALRMGHLVPIC
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEE
FTSAELDIGIASLLEIMVKLMPSPLEANPPQFIKGFGDKAVPVDVTQSPDDHVLAQVFRV
EECCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCEEECCCCCCHHHHHHHHHH
GIDPYFGRVAVFRLYQGTLEAGMRLFIGADRKPVKVAHLIKLQGAETTEVEKAIPGDICA
CCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEEECCCCCHHHHHCCCCCEEE
LCKIDELEVGSVLHDSHDEDEFHLRELKMPQPIFGLAVSPKRRGDEQKIAEVLAKLIAED
HEECCCCCCCHHHCCCCCCCHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCC
PSLAVSQNDAEGQTVLSGLGDLHLQIALEKAQSVFRVDMETCKPAVAYRETVCKAATARY
CCEEEECCCCCHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RHKKQSGGAGQFGEVELTVEPLPRGQGFEFVSKVVGGAVPTQFIPAVEKGVREALKVGRL
HHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
GGYPVEDVRVTVLDGKHHSVDSKEIAFVMAGKKAFYEAFLQANPVILEPLVSMEILVSAE
CCCCCCCEEEEEECCCCCCCCCCEEEEEEECHHHHHHHHHHCCCEEEHHHHCEEEEEECH
DVGDITGHLSSSRAMVCGTEARRDGKVKVLAEAPLSTVDDYATRLKSMTSGEGEFTLSFA
HHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEE
RYEVVPPAVQQSLLRTIEDKDD
EEECCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]