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The map label for this gene is yfcG [H]

Identifier: 119774224

GI number: 119774224

Start: 1314986

End: 1315654

Strand: Reverse

Name: yfcG [H]

Synonym: Sama_1087

Alternate gene names: 119774224

Gene position: 1315654-1314986 (Counterclockwise)

Preceding gene: 119774225

Following gene: 119774223

Centisome position: 30.55

GC content: 55.46

Gene sequence:

>669_bases
ATGATTGAGCTTTATACCGCCGCGACCCCCAACGGCCATAAAATTTCCATTGCCCTTGAAGAATTAGGGCTCGAGTATCG
GGTACATGCCCTTGATCTCATGACCCTTGAGCAAAAAAAGCCCGAGTTTCTGGCCATTAACCCCAATGGCCGTATTCCGG
CAATTGTAGACACAGATAACGACGACTTTGCGGTATTTGAGTCGGGTGCCATCTTGTTATATCTGGCCGAGAAAACCGGC
AAGCTGCTGCCGACCGAGCCCAAGGCACGCTCTGAGGTTATCCAGTGGCTGATGTTCCAGATGGGGGGCGTTGGCCCCAT
GATGGGTCAGGCGAACGTGTTTTACCGCTACTTTCCCGAAAAAATTCCGGCCGCCATTGAGCGTTATCAAAAGGAAGGAC
GGCGCCTGTTCGAGGTGATGAATACCCAGCTTGAAAAGCATGCGTATCTCGCCGGAGACGAGTACAGCGTCGCCGATATC
GCCACCTACCCCTGGGTACGTATCTATGACTGGAGCGGCGTGGATATCAGTGGGTTGGATGCGCTGCAGCACTGGCTCGA
GCGCATCACTGCCCGGCCCGCCGTGGCCAAGGGCCTTGCTGTGCCGCCACCAAGTGAGAAATCCGCCGAAGAGCGTGCCA
AAGACATCGCCAAAATGGTCACCCGCTGA

Upstream 100 bases:

>100_bases
TGACCGACGCCATGCCCAACATTCGCCGCTGGCACGCAGCCATCGCCGCACGTCCCGCCGTGGCCACCCTGCTGGCAAGC
CAGCAATAGAGGAGTACATC

Downstream 100 bases:

>100_bases
CTCGCCGGTTACCAGCCATCCTCAGATGCGCCCTCGCGGCGCATCTGCTACAATCGGCGCCGGATTTTTTACTCAGGCAA
GCCCATGTCACACCCAGCAC

Product: glutathione S-transferase family protein

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MIELYTAATPNGHKISIALEELGLEYRVHALDLMTLEQKKPEFLAINPNGRIPAIVDTDNDDFAVFESGAILLYLAEKTG
KLLPTEPKARSEVIQWLMFQMGGVGPMMGQANVFYRYFPEKIPAAIERYQKEGRRLFEVMNTQLEKHAYLAGDEYSVADI
ATYPWVRIYDWSGVDISGLDALQHWLERITARPAVAKGLAVPPPSEKSAEERAKDIAKMVTR

Sequences:

>Translated_222_residues
MIELYTAATPNGHKISIALEELGLEYRVHALDLMTLEQKKPEFLAINPNGRIPAIVDTDNDDFAVFESGAILLYLAEKTG
KLLPTEPKARSEVIQWLMFQMGGVGPMMGQANVFYRYFPEKIPAAIERYQKEGRRLFEVMNTQLEKHAYLAGDEYSVADI
ATYPWVRIYDWSGVDISGLDALQHWLERITARPAVAKGLAVPPPSEKSAEERAKDIAKMVTR
>Mature_222_residues
MIELYTAATPNGHKISIALEELGLEYRVHALDLMTLEQKKPEFLAINPNGRIPAIVDTDNDDFAVFESGAILLYLAEKTG
KLLPTEPKARSEVIQWLMFQMGGVGPMMGQANVFYRYFPEKIPAAIERYQKEGRRLFEVMNTQLEKHAYLAGDEYSVADI
ATYPWVRIYDWSGVDISGLDALQHWLERITARPAVAKGLAVPPPSEKSAEERAKDIAKMVTR

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=203, Percent_Identity=50.2463054187192, Blast_Score=204, Evalue=3e-54,
Organism=Escherichia coli, GI87082195, Length=215, Percent_Identity=40.4651162790698, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI87081789, Length=169, Percent_Identity=34.3195266272189, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324100, Length=232, Percent_Identity=34.9137931034483, Blast_Score=133, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28571670, Length=171, Percent_Identity=36.8421052631579, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI85725204, Length=193, Percent_Identity=37.3056994818653, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17737923, Length=193, Percent_Identity=37.3056994818653, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17864592, Length=170, Percent_Identity=37.6470588235294, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI45549270, Length=188, Percent_Identity=32.4468085106383, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17933730, Length=192, Percent_Identity=32.2916666666667, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17864598, Length=187, Percent_Identity=33.1550802139037, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24646249, Length=173, Percent_Identity=35.8381502890173, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17864594, Length=184, Percent_Identity=33.1521739130435, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17864596, Length=188, Percent_Identity=28.1914893617021, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24646251, Length=188, Percent_Identity=31.9148936170213, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24654975, Length=191, Percent_Identity=30.3664921465969, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24654965, Length=197, Percent_Identity=25.8883248730964, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 24999; Mature: 24999

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELYTAATPNGHKISIALEELGLEYRVHALDLMTLEQKKPEFLAINPNGRIPAIVDTDN
CEEEEEECCCCCCEEEEEHHHCCCEEEEEHHHEEEHHCCCCCEEEECCCCCCCEEEECCC
DDFAVFESGAILLYLAEKTGKLLPTEPKARSEVIQWLMFQMGGVGPMMGQANVFYRYFPE
CCEEEEECCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHEECCCH
KIPAAIERYQKEGRRLFEVMNTQLEKHAYLAGDEYSVADIATYPWVRIYDWSGVDISGLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHCCCCEEEEEECCCCCCCHHH
ALQHWLERITARPAVAKGLAVPPPSEKSAEERAKDIAKMVTR
HHHHHHHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIELYTAATPNGHKISIALEELGLEYRVHALDLMTLEQKKPEFLAINPNGRIPAIVDTDN
CEEEEEECCCCCCEEEEEHHHCCCEEEEEHHHEEEHHCCCCCEEEECCCCCCCEEEECCC
DDFAVFESGAILLYLAEKTGKLLPTEPKARSEVIQWLMFQMGGVGPMMGQANVFYRYFPE
CCEEEEECCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHEECCCH
KIPAAIERYQKEGRRLFEVMNTQLEKHAYLAGDEYSVADIATYPWVRIYDWSGVDISGLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHCCCCEEEEEECCCCCCCHHH
ALQHWLERITARPAVAKGLAVPPPSEKSAEERAKDIAKMVTR
HHHHHHHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]