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The map label for this gene is rsmB [H]

Identifier: 119774223

GI number: 119774223

Start: 1313537

End: 1314901

Strand: Reverse

Name: rsmB [H]

Synonym: Sama_1086

Alternate gene names: 119774223

Gene position: 1314901-1313537 (Counterclockwise)

Preceding gene: 119774224

Following gene: 119774222

Centisome position: 30.54

GC content: 59.56

Gene sequence:

>1365_bases
ATGTCACACCCAGCACCTCTCTCGTCGGCCGAGCGCCGCGCCATCAGTTATGCCAACACCCTGCATCTGCTGGTGTCGCA
TATTTTTAAGCAGCGCGAAGGCGCCGACCGGGTACTGGCCAACTATTTCCGTGAGCACAAAAAGCACGGTTCCAAAGACC
GTAAGCTTATCCGTGAAACCCTGTTTGGCCTGTTCCGTTGGTGGGGCTGGCTGAAAAACCTGCCTGCGGCCGATGACGCC
AATGCCAATATTGAAGACTCGGGCTTTTCCTCTGGCTTGGGCGAGGCCCACAGCCCGCGTTGGTTTACCCAATTAAGCCT
GGTGGCCGCCATTGAAAATCATCAATGGCAGGATATTCGCAGCGGTTGGCTTTCTCAGGCCAATCTGTCTCAGTTGGAAA
TACCTGCCTTTGGCGATACGCCAGAAAACCTCAACATCATTTGCGCCGCCTTAATTAAGCAGTTTGGTGGTGAATTCGCC
CCGCCGAACCTCCTTCCCGACTGGGCCTGGGAGCACATCAGCGTGGCCGGGAGTGACAAGCTCGCCTTTGTCGATGCCCT
GTGCCGCCGCCCGCCCCTGTGGACCCGCGCCCAGGGAACAAGCCGCGAACAGGTGCTCAAGCAGCTTGAGGCAGATGACA
TCGGCGCCGTTCCAAGTAAGGTGTTTGCTGATGCCATCGAGCTTGCCAGCCAAAGCATCAATCTGGATGCGGTGACGGCC
TATACGTCGGGCAAGCTTGAGGTGCAGGATTTGGCTTCTCAGGCCATTGGTGAAGTGGCAGCTCCCAAGGCGGGCGAGCG
TTGGTGGGATGCCTGCGCAGGCGCAGGCGGTAAGAGCCTGCAGCTTTTCTCACTCATGCAAAAACGCGGCGGCGTGGGTG
AACTCGTCGCCTCAGATATTCGTCCCAAGGCACTGGAAGAACTGCTGCGCCGCGCCGACAAAGCCGGGGTTGCGCCGATT
CAGCTCAGCCCCTGGCGCAGCGACAAGCTGCCGGTCAAGGCAGACTATTTTGATGGCGTGCTGGTGGATGCGCCCTGCTC
CTGTACCGGCACCTGGCGCCGCAACCCAGACATGCGCTGGATTGATGATGCATCAGCTATTTTGGACAAGCCCGCGCTGC
AGCTGGATATTTTGCGCCGCGCCAGCGCCGCCGTGCGCAGCGGCGGCGTGCTGGTGTACGCCACCTGCTCCTTGGCCCGC
GCCGAAAACGAAGCCGTGGTCGAGGCCTTTTTGGCCTCAGATGAAGATTTTGAACTTGATACCACCGCACATCCCTTCAG
TGGTGAACACTGCGCGGTTATGACCCTTTGGCCGCAGCAGGCCAATGCCGACGGTATGTTTGTGGCCCGCATGCGACGCC
GCTGA

Upstream 100 bases:

>100_bases
AATGGTCACCCGCTGACTCGCCGGTTACCAGCCATCCTCAGATGCGCCCTCGCGGCGCATCTGCTACAATCGGCGCCGGA
TTTTTTACTCAGGCAAGCCC

Downstream 100 bases:

>100_bases
GGCAGGTTTGGGGCGGTCATAAAATCGAACACAAAAGAATCGCCCGGGGCTGGGATTTAAGGCTGGTTTCAGACTGTAAC
CGCCTCGTTGCTTCGGGCAA

Product: Fmu (Sun)

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MSHPAPLSSAERRAISYANTLHLLVSHIFKQREGADRVLANYFREHKKHGSKDRKLIRETLFGLFRWWGWLKNLPAADDA
NANIEDSGFSSGLGEAHSPRWFTQLSLVAAIENHQWQDIRSGWLSQANLSQLEIPAFGDTPENLNIICAALIKQFGGEFA
PPNLLPDWAWEHISVAGSDKLAFVDALCRRPPLWTRAQGTSREQVLKQLEADDIGAVPSKVFADAIELASQSINLDAVTA
YTSGKLEVQDLASQAIGEVAAPKAGERWWDACAGAGGKSLQLFSLMQKRGGVGELVASDIRPKALEELLRRADKAGVAPI
QLSPWRSDKLPVKADYFDGVLVDAPCSCTGTWRRNPDMRWIDDASAILDKPALQLDILRRASAAVRSGGVLVYATCSLAR
AENEAVVEAFLASDEDFELDTTAHPFSGEHCAVMTLWPQQANADGMFVARMRRR

Sequences:

>Translated_454_residues
MSHPAPLSSAERRAISYANTLHLLVSHIFKQREGADRVLANYFREHKKHGSKDRKLIRETLFGLFRWWGWLKNLPAADDA
NANIEDSGFSSGLGEAHSPRWFTQLSLVAAIENHQWQDIRSGWLSQANLSQLEIPAFGDTPENLNIICAALIKQFGGEFA
PPNLLPDWAWEHISVAGSDKLAFVDALCRRPPLWTRAQGTSREQVLKQLEADDIGAVPSKVFADAIELASQSINLDAVTA
YTSGKLEVQDLASQAIGEVAAPKAGERWWDACAGAGGKSLQLFSLMQKRGGVGELVASDIRPKALEELLRRADKAGVAPI
QLSPWRSDKLPVKADYFDGVLVDAPCSCTGTWRRNPDMRWIDDASAILDKPALQLDILRRASAAVRSGGVLVYATCSLAR
AENEAVVEAFLASDEDFELDTTAHPFSGEHCAVMTLWPQQANADGMFVARMRRR
>Mature_453_residues
SHPAPLSSAERRAISYANTLHLLVSHIFKQREGADRVLANYFREHKKHGSKDRKLIRETLFGLFRWWGWLKNLPAADDAN
ANIEDSGFSSGLGEAHSPRWFTQLSLVAAIENHQWQDIRSGWLSQANLSQLEIPAFGDTPENLNIICAALIKQFGGEFAP
PNLLPDWAWEHISVAGSDKLAFVDALCRRPPLWTRAQGTSREQVLKQLEADDIGAVPSKVFADAIELASQSINLDAVTAY
TSGKLEVQDLASQAIGEVAAPKAGERWWDACAGAGGKSLQLFSLMQKRGGVGELVASDIRPKALEELLRRADKAGVAPIQ
LSPWRSDKLPVKADYFDGVLVDAPCSCTGTWRRNPDMRWIDDASAILDKPALQLDILRRASAAVRSGGVLVYATCSLARA
ENEAVVEAFLASDEDFELDTTAHPFSGEHCAVMTLWPQQANADGMFVARMRRR

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=239, Percent_Identity=28.8702928870293, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI76150623, Length=239, Percent_Identity=28.8702928870293, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI11545785, Length=210, Percent_Identity=31.4285714285714, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI39995082, Length=193, Percent_Identity=28.4974093264249, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI301336155, Length=193, Percent_Identity=28.4974093264249, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI32698918, Length=175, Percent_Identity=29.7142857142857, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI2367212, Length=445, Percent_Identity=26.9662921348315, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI87081985, Length=233, Percent_Identity=27.0386266094421, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17536757, Length=300, Percent_Identity=26.3333333333333, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25143471, Length=266, Percent_Identity=26.6917293233083, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324268, Length=263, Percent_Identity=25.8555133079848, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319447, Length=184, Percent_Identity=31.5217391304348, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI22024126, Length=237, Percent_Identity=26.1603375527426, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21355201, Length=218, Percent_Identity=27.9816513761468, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 49949; Mature: 49818

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHPAPLSSAERRAISYANTLHLLVSHIFKQREGADRVLANYFREHKKHGSKDRKLIRET
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
LFGLFRWWGWLKNLPAADDANANIEDSGFSSGLGEAHSPRWFTQLSLVAAIENHQWQDIR
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
SGWLSQANLSQLEIPAFGDTPENLNIICAALIKQFGGEFAPPNLLPDWAWEHISVAGSDK
HHHCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEECCCCH
LAFVDALCRRPPLWTRAQGTSREQVLKQLEADDIGAVPSKVFADAIELASQSINLDAVTA
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEE
YTSGKLEVQDLASQAIGEVAAPKAGERWWDACAGAGGKSLQLFSLMQKRGGVGELVASDI
ECCCCEEHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHCC
RPKALEELLRRADKAGVAPIQLSPWRSDKLPVKADYFDGVLVDAPCSCTGTWRRNPDMRW
CHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCE
IDDASAILDKPALQLDILRRASAAVRSGGVLVYATCSLARAENEAVVEAFLASDEDFELD
ECCHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEECHHHHCCCHHHHHHHHCCCCCCCCC
TTAHPFSGEHCAVMTLWPQQANADGMFVARMRRR
CCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
SHPAPLSSAERRAISYANTLHLLVSHIFKQREGADRVLANYFREHKKHGSKDRKLIRET
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
LFGLFRWWGWLKNLPAADDANANIEDSGFSSGLGEAHSPRWFTQLSLVAAIENHQWQDIR
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
SGWLSQANLSQLEIPAFGDTPENLNIICAALIKQFGGEFAPPNLLPDWAWEHISVAGSDK
HHHCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEECCCCH
LAFVDALCRRPPLWTRAQGTSREQVLKQLEADDIGAVPSKVFADAIELASQSINLDAVTA
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEE
YTSGKLEVQDLASQAIGEVAAPKAGERWWDACAGAGGKSLQLFSLMQKRGGVGELVASDI
ECCCCEEHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHCC
RPKALEELLRRADKAGVAPIQLSPWRSDKLPVKADYFDGVLVDAPCSCTGTWRRNPDMRW
CHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCE
IDDASAILDKPALQLDILRRASAAVRSGGVLVYATCSLARAENEAVVEAFLASDEDFELD
ECCHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEECHHHHCCCHHHHHHHHCCCCCCCCC
TTAHPFSGEHCAVMTLWPQQANADGMFVARMRRR
CCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]