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The map label for this gene is porA [H]

Identifier: 119774210

GI number: 119774210

Start: 1299682

End: 1300608

Strand: Direct

Name: porA [H]

Synonym: Sama_1073

Alternate gene names: 119774210

Gene position: 1299682-1300608 (Clockwise)

Preceding gene: 119774207

Following gene: 119774211

Centisome position: 30.18

GC content: 51.46

Gene sequence:

>927_bases
ATGATGAACGCTTTTAACAAAACTCTGCTTGTTTCCGCGCTGACCGCTGCTTCTTTGGCTTCTGCCCAAGCGGCTGAACC
TTTAACTGTTTACGGTAAACTGAACGTAACAGTACAGTCTAACGACGAAGCCGGTGAATCTGAAACCGTAGTACAGAGCA
ACGCCTCTCGTCTGGGTGTTAAAGGTGCTTTCGAACTGAGCTCTTCTCTCGAAGCCTTCTACACCATCGAGTATGAAGTG
GATGCCGGCAGTGATGCCAAGGAAAACTTCCTGGCCCGTAACCAGTTTGTGGGTCTGAAAGGCAATTTCGGTGCGCTGTC
TGTGGGTCGTAACGACACCATGCTGAAAATCGCCCAGGGTAAAGTTGACCAGTTCAACGACCTGTCAGGCGACCTGAAGA
GCCTGTTCAAAGGTGAAAACCGTATCGAGCAAACCGTGACTTACCTGTCACCAGAGTTCGGTGGTTTCAAAGTGGGTGCT
ACCTACGCAGCTGAAGGTGCCAAGTCTCAGGCCGGTGAAGACGGTTTCTCTCTGGCCGCCATGTACGGTGATGCCAGCCT
GAAGAAATCCGCTTTCTACGCTTCTGTTGCCTATGACAGTGAAGTAAAAGGCTACGACATCCTGCGTGCCACTGTTCAAG
CCAAGCTGGCTGGCCTGGTTTTGGGTGGTATGTACCAGCAGGAAGAGAAGTCAGTTGATGGTGACAGCAAGACAGGTTAC
CTGGTCAGTGCCGCTTACAATATCGCTGACGTGACCCTGAAGGGTCAGTTCCAGGACATGGAAGACAAGGGTGACTCCTG
GTCTATCGGTGCTGACTACAAGCTGGGCAAGCCAACCAAAATCTTCGCCTTCTACACCAGCCGTGACATGGAGTCTGCCG
AAGACACCGACAACTACATTGGTGTGGGTATCGAACACAAGTTCTAA

Upstream 100 bases:

>100_bases
CGCTTAAGTGGATGCTGAAATAAAACTGAAACACTCAGATTGCAAACTTGCGCTCGTTCCAAACCAATAACCAGACGCAC
TGAACGTCGCAAAGGATTAA

Downstream 100 bases:

>100_bases
TCGGACTCAGTGACAAAAAAGGAGGCTTAGCCTCCTTTTTTCATTTTTATAAACAGCTAGTTAATTAGTCTGATTATGAC
AATTTCTGCTGAAATGTGTC

Product: porin

Products: NA

Alternate protein names: PIA; Protein IA; Class 1 protein [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MMNAFNKTLLVSALTAASLASAQAAEPLTVYGKLNVTVQSNDEAGESETVVQSNASRLGVKGAFELSSSLEAFYTIEYEV
DAGSDAKENFLARNQFVGLKGNFGALSVGRNDTMLKIAQGKVDQFNDLSGDLKSLFKGENRIEQTVTYLSPEFGGFKVGA
TYAAEGAKSQAGEDGFSLAAMYGDASLKKSAFYASVAYDSEVKGYDILRATVQAKLAGLVLGGMYQQEEKSVDGDSKTGY
LVSAAYNIADVTLKGQFQDMEDKGDSWSIGADYKLGKPTKIFAFYTSRDMESAEDTDNYIGVGIEHKF

Sequences:

>Translated_308_residues
MMNAFNKTLLVSALTAASLASAQAAEPLTVYGKLNVTVQSNDEAGESETVVQSNASRLGVKGAFELSSSLEAFYTIEYEV
DAGSDAKENFLARNQFVGLKGNFGALSVGRNDTMLKIAQGKVDQFNDLSGDLKSLFKGENRIEQTVTYLSPEFGGFKVGA
TYAAEGAKSQAGEDGFSLAAMYGDASLKKSAFYASVAYDSEVKGYDILRATVQAKLAGLVLGGMYQQEEKSVDGDSKTGY
LVSAAYNIADVTLKGQFQDMEDKGDSWSIGADYKLGKPTKIFAFYTSRDMESAEDTDNYIGVGIEHKF
>Mature_308_residues
MMNAFNKTLLVSALTAASLASAQAAEPLTVYGKLNVTVQSNDEAGESETVVQSNASRLGVKGAFELSSSLEAFYTIEYEV
DAGSDAKENFLARNQFVGLKGNFGALSVGRNDTMLKIAQGKVDQFNDLSGDLKSLFKGENRIEQTVTYLSPEFGGFKVGA
TYAAEGAKSQAGEDGFSLAAMYGDASLKKSAFYASVAYDSEVKGYDILRATVQAKLAGLVLGGMYQQEEKSVDGDSKTGY
LVSAAYNIADVTLKGQFQDMEDKGDSWSIGADYKLGKPTKIFAFYTSRDMESAEDTDNYIGVGIEHKF

Specific function: Serves as a slightly cation selective porin. Major antigen on the gonococcal cell surface and it may have pathogenic properties in addition to its porin activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Gram-negative porin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013793
- InterPro:   IPR001702
- InterPro:   IPR002299 [H]

Pfam domain/function: PF00267 Porin_1 [H]

EC number: NA

Molecular weight: Translated: 33013; Mature: 33013

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNAFNKTLLVSALTAASLASAQAAEPLTVYGKLNVTVQSNDEAGESETVVQSNASRLGV
CCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCHHHHCCCHHCCC
KGAFELSSSLEAFYTIEYEVDAGSDAKENFLARNQFVGLKGNFGALSVGRNDTMLKIAQG
CEEEHHCCCCEEEEEEEEEECCCCCHHHHHHHHCCEEEECCCCCEEEECCCCCEEEEECC
KVDQFNDLSGDLKSLFKGENRIEQTVTYLSPEFGGFKVGATYAAEGAKSQAGEDGFSLAA
CCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCEEECCEEECCCCCCCCCCCCEEEEE
MYGDASLKKSAFYASVAYDSEVKGYDILRATVQAKLAGLVLGGMYQQEEKSVDGDSKTGY
EECCCCHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCE
LVSAAYNIADVTLKGQFQDMEDKGDSWSIGADYKLGKPTKIFAFYTSRDMESAEDTDNYI
EEEEEECEEEEEEECCCCCCCCCCCCEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCEE
GVGIEHKF
EEEEEECC
>Mature Secondary Structure
MMNAFNKTLLVSALTAASLASAQAAEPLTVYGKLNVTVQSNDEAGESETVVQSNASRLGV
CCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCHHHHCCCHHCCC
KGAFELSSSLEAFYTIEYEVDAGSDAKENFLARNQFVGLKGNFGALSVGRNDTMLKIAQG
CEEEHHCCCCEEEEEEEEEECCCCCHHHHHHHHCCEEEECCCCCEEEECCCCCEEEEECC
KVDQFNDLSGDLKSLFKGENRIEQTVTYLSPEFGGFKVGATYAAEGAKSQAGEDGFSLAA
CCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCEEECCEEECCCCCCCCCCCCEEEEE
MYGDASLKKSAFYASVAYDSEVKGYDILRATVQAKLAGLVLGGMYQQEEKSVDGDSKTGY
EECCCCHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCE
LVSAAYNIADVTLKGQFQDMEDKGDSWSIGADYKLGKPTKIFAFYTSRDMESAEDTDNYI
EEEEEECEEEEEEECCCCCCCCCCCCEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCEE
GVGIEHKF
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3122212 [H]