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The map label for this gene is oadA [H]

Identifier: 119774189

GI number: 119774189

Start: 1273164

End: 1274963

Strand: Direct

Name: oadA [H]

Synonym: Sama_1052

Alternate gene names: 119774189

Gene position: 1273164-1274963 (Clockwise)

Preceding gene: 119774188

Following gene: 119774190

Centisome position: 29.57

GC content: 57.22

Gene sequence:

>1800_bases
ATGACCAAAGCCTTGGCCCTTACCGATGTGGTGCTGCGCGATGCGCACCAATCCCTGCTAGCTACCCGTTTACGTATTGA
AGACATGTTGCCCATCGCTGCCAAATTGGATCAGGTGGGCTATTGGTCACTGGAGACTTGGGGCGGCGCGACTTTCGATG
CCTGTATCCGCTATCTGGGGGAGGACCCCTGGGAGCGCCTGCGGCTGCTCAAGCAAGCCATGCCCAACACCCCGATGCAG
ATGCTGCTGCGGGGTCAGAACCTGCTGGGTTATCGCCACTATGCCGACGATTTGGTGCACAGGTTCGTAGAGCGCGCCCA
CGACAACGGCATGGACGTGTTTCGGGTATTCGATGCCATGAACGATGTGCGTAACCTGCAAGAGGCGGTGCGTGCCGTGA
AGCAGGTGGGCGCCCATGCCCAGGGCACCATTTCCTACACCACCAGCCCGGTACATAACCTGGACACCTGGGTAGATATG
GCCAAGCGCCTTGAGGATCTGGGCTGCGATTCACTCTGTATCAAAGACATGGCCGGTCTGCTGCGCCCTATGGAAGCCTT
CGAGCTGGTGAGCAGGCTTAAATCGCAAACCGGGCTGATGGTGGCCATGCACAGCCATGCCACCACCGGGCTTTCTACCG
CCACCTATCAAAAGGCGATTGAGGCCGGTATTGATGTGCTGGATACCGCGATTTCGTCCATGAGCCAGACCTATGGCCAC
AGTGCCACCGAGACCCTGGTGGCCATGGTAGAAGACACCGAGCGCTCAACCGGATTGGATATGGCGCTTTTGGAAGAGAT
TGCCGCCTATTTCCGTGAGGTGCGTAAAAAGTACGCCAAATTCGAAGGCGCGCTGCAGGGCATTGATTCCCGAATTCTAC
GCGCTCAGGTGCCAGGTGGCATGCTCACCAATATGGAGAGTCAGCTTAAAGAGCAGGGCGCCAGCGATAAACTCGATTTG
GTGCTCGATGAAATCCCCCGAGTGCGCGAAGACCTGGGTTTCTTGCCTCTTGTTACTCCAACCTCACAAATCGTCGGCAC
CCAGGCGGTGATCAATGTGCTCACCGGTGAGCGCTACAAGTCGCTCACCAAAGAAACTGAAGGGGTACTCAAGGGCGAAT
ATGGTGCCACCCCGGCGCCGGTAAACGCTGAGCTGCAGCAGCGGGTACTTAAGGGGGCTGAGCCTGTTACCTGTCGCCCT
GCCGATCTGCTCACTCCAGAGATGGTGCGTCTTCGCGCCGAGCTGGTCCAAAAGGCCGTGGCCGAGAATATAACGCTCAG
TGAAGATCTGGATGATGATGTGCTTACCTATGCGCTTTTCCCTCAGATTGGTCTGCAGTTTCTCAAAAACCGTGGCAATG
CCGATGCCTTTGAGCCTGTGCCTGTGGCGGTGCTTGCCGCCTCGTCAGCGCCAGTCAGGGTTGCCTCAGGGCCAGAAACT
TACACGGTGAAGGTAGATGGTCAAACCTATGTGGTAGAGGTTGCTGCGGGCGGCGAAATCAGCCAAATCCAGACTCAGGG
GGTAAGTCAGTCCAGTGCCTCAGTTGCCCCAGTTGCCACAGCGGCTGCGCCTGTAAGCCACGAAATTAAACTGGAAATGA
GCGCGCCCCTGTCTGGCAATATCTTCAAAATTCATGTGTCGCCCGGCGATACGGTGAAGGCGGGGGATGTGGTGATCATC
CTCGAAGCCATGAAGATGGAAACCGAAATCCGTGCCCAGGCCGACGGGGTTATTGCCCGTCTATGGGTGAAAGAAGGCGA
CTCGGTTGCCGTTGGCGCTCAGCTGTTGTCGTTGGCCTAA

Upstream 100 bases:

>100_bases
AGGCGCCCAGTATTTCATCTAAGCCCCAAGGGCTGGATCCGCGTCTGGTGGCCGCTATCACCTCTGCCGTACAACAATAT
CGAGCCCAGGAGGGACGTTC

Downstream 100 bases:

>100_bases
GGAGGCATCATGGAAGGATTGATGGCTTTTTGGGCCGAAACGGGTATTGCCCACTTTACCCTGGGGCAGCTACTGATGAT
GGCGGTGGGACTGGTGCTCT

Product: oxaloacetate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 599; Mature: 598

Protein sequence:

>599_residues
MTKALALTDVVLRDAHQSLLATRLRIEDMLPIAAKLDQVGYWSLETWGGATFDACIRYLGEDPWERLRLLKQAMPNTPMQ
MLLRGQNLLGYRHYADDLVHRFVERAHDNGMDVFRVFDAMNDVRNLQEAVRAVKQVGAHAQGTISYTTSPVHNLDTWVDM
AKRLEDLGCDSLCIKDMAGLLRPMEAFELVSRLKSQTGLMVAMHSHATTGLSTATYQKAIEAGIDVLDTAISSMSQTYGH
SATETLVAMVEDTERSTGLDMALLEEIAAYFREVRKKYAKFEGALQGIDSRILRAQVPGGMLTNMESQLKEQGASDKLDL
VLDEIPRVREDLGFLPLVTPTSQIVGTQAVINVLTGERYKSLTKETEGVLKGEYGATPAPVNAELQQRVLKGAEPVTCRP
ADLLTPEMVRLRAELVQKAVAENITLSEDLDDDVLTYALFPQIGLQFLKNRGNADAFEPVPVAVLAASSAPVRVASGPET
YTVKVDGQTYVVEVAAGGEISQIQTQGVSQSSASVAPVATAAAPVSHEIKLEMSAPLSGNIFKIHVSPGDTVKAGDVVII
LEAMKMETEIRAQADGVIARLWVKEGDSVAVGAQLLSLA

Sequences:

>Translated_599_residues
MTKALALTDVVLRDAHQSLLATRLRIEDMLPIAAKLDQVGYWSLETWGGATFDACIRYLGEDPWERLRLLKQAMPNTPMQ
MLLRGQNLLGYRHYADDLVHRFVERAHDNGMDVFRVFDAMNDVRNLQEAVRAVKQVGAHAQGTISYTTSPVHNLDTWVDM
AKRLEDLGCDSLCIKDMAGLLRPMEAFELVSRLKSQTGLMVAMHSHATTGLSTATYQKAIEAGIDVLDTAISSMSQTYGH
SATETLVAMVEDTERSTGLDMALLEEIAAYFREVRKKYAKFEGALQGIDSRILRAQVPGGMLTNMESQLKEQGASDKLDL
VLDEIPRVREDLGFLPLVTPTSQIVGTQAVINVLTGERYKSLTKETEGVLKGEYGATPAPVNAELQQRVLKGAEPVTCRP
ADLLTPEMVRLRAELVQKAVAENITLSEDLDDDVLTYALFPQIGLQFLKNRGNADAFEPVPVAVLAASSAPVRVASGPET
YTVKVDGQTYVVEVAAGGEISQIQTQGVSQSSASVAPVATAAAPVSHEIKLEMSAPLSGNIFKIHVSPGDTVKAGDVVII
LEAMKMETEIRAQADGVIARLWVKEGDSVAVGAQLLSLA
>Mature_598_residues
TKALALTDVVLRDAHQSLLATRLRIEDMLPIAAKLDQVGYWSLETWGGATFDACIRYLGEDPWERLRLLKQAMPNTPMQM
LLRGQNLLGYRHYADDLVHRFVERAHDNGMDVFRVFDAMNDVRNLQEAVRAVKQVGAHAQGTISYTTSPVHNLDTWVDMA
KRLEDLGCDSLCIKDMAGLLRPMEAFELVSRLKSQTGLMVAMHSHATTGLSTATYQKAIEAGIDVLDTAISSMSQTYGHS
ATETLVAMVEDTERSTGLDMALLEEIAAYFREVRKKYAKFEGALQGIDSRILRAQVPGGMLTNMESQLKEQGASDKLDLV
LDEIPRVREDLGFLPLVTPTSQIVGTQAVINVLTGERYKSLTKETEGVLKGEYGATPAPVNAELQQRVLKGAEPVTCRPA
DLLTPEMVRLRAELVQKAVAENITLSEDLDDDVLTYALFPQIGLQFLKNRGNADAFEPVPVAVLAASSAPVRVASGPETY
TVKVDGQTYVVEVAAGGEISQIQTQGVSQSSASVAPVATAAAPVSHEIKLEMSAPLSGNIFKIHVSPGDTVKAGDVVIIL
EAMKMETEIRAQADGVIARLWVKEGDSVAVGAQLLSLA

Specific function: Lyase and sodium transporter [H]

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=632, Percent_Identity=31.8037974683544, Blast_Score=265, Evalue=9e-71,
Organism=Homo sapiens, GI106049295, Length=632, Percent_Identity=31.8037974683544, Blast_Score=265, Evalue=9e-71,
Organism=Homo sapiens, GI106049292, Length=632, Percent_Identity=31.8037974683544, Blast_Score=265, Evalue=9e-71,
Organism=Caenorhabditis elegans, GI17562816, Length=625, Percent_Identity=31.84, Blast_Score=286, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6319695, Length=623, Percent_Identity=33.0658105939005, Blast_Score=313, Evalue=5e-86,
Organism=Saccharomyces cerevisiae, GI6321376, Length=620, Percent_Identity=32.5806451612903, Blast_Score=303, Evalue=8e-83,
Organism=Drosophila melanogaster, GI24652212, Length=632, Percent_Identity=31.6455696202532, Blast_Score=283, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24652210, Length=632, Percent_Identity=31.6455696202532, Blast_Score=283, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24652214, Length=632, Percent_Identity=31.6455696202532, Blast_Score=283, Evalue=3e-76,
Organism=Drosophila melanogaster, GI19921944, Length=632, Percent_Identity=31.6455696202532, Blast_Score=283, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24652216, Length=632, Percent_Identity=31.6455696202532, Blast_Score=283, Evalue=3e-76,
Organism=Drosophila melanogaster, GI281363050, Length=632, Percent_Identity=31.8037974683544, Blast_Score=282, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24652224, Length=632, Percent_Identity=31.8037974683544, Blast_Score=282, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24652222, Length=632, Percent_Identity=31.8037974683544, Blast_Score=282, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24652220, Length=632, Percent_Identity=31.8037974683544, Blast_Score=282, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24652218, Length=632, Percent_Identity=31.8037974683544, Blast_Score=282, Evalue=5e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR003379
- InterPro:   IPR005776
- InterPro:   IPR000891
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =4.1.1.3 [H]

Molecular weight: Translated: 65100; Mature: 64969

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKALALTDVVLRDAHQSLLATRLRIEDMLPIAAKLDQVGYWSLETWGGATFDACIRYLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHC
EDPWERLRLLKQAMPNTPMQMLLRGQNLLGYRHYADDLVHRFVERAHDNGMDVFRVFDAM
CCHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
NDVRNLQEAVRAVKQVGAHAQGTISYTTSPVHNLDTWVDMAKRLEDLGCDSLCIKDMAGL
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LRPMEAFELVSRLKSQTGLMVAMHSHATTGLSTATYQKAIEAGIDVLDTAISSMSQTYGH
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SATETLVAMVEDTERSTGLDMALLEEIAAYFREVRKKYAKFEGALQGIDSRILRAQVPGG
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
MLTNMESQLKEQGASDKLDLVLDEIPRVREDLGFLPLVTPTSQIVGTQAVINVLTGERYK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SLTKETEGVLKGEYGATPAPVNAELQQRVLKGAEPVTCRPADLLTPEMVRLRAELVQKAV
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHHH
AENITLSEDLDDDVLTYALFPQIGLQFLKNRGNADAFEPVPVAVLAASSAPVRVASGPET
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEECCCCE
YTVKVDGQTYVVEVAAGGEISQIQTQGVSQSSASVAPVATAAAPVSHEIKLEMSAPLSGN
EEEEECCCEEEEEEECCCCHHHHHHCCCCCCCCCCCCHHHHCCCCCCEEEEEECCCCCCC
IFKIHVSPGDTVKAGDVVIILEAMKMETEIRAQADGVIARLWVKEGDSVAVGAQLLSLA
EEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHHCCEEEEEEECCCCCEEHHHHHHHCC
>Mature Secondary Structure 
TKALALTDVVLRDAHQSLLATRLRIEDMLPIAAKLDQVGYWSLETWGGATFDACIRYLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHC
EDPWERLRLLKQAMPNTPMQMLLRGQNLLGYRHYADDLVHRFVERAHDNGMDVFRVFDAM
CCHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
NDVRNLQEAVRAVKQVGAHAQGTISYTTSPVHNLDTWVDMAKRLEDLGCDSLCIKDMAGL
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LRPMEAFELVSRLKSQTGLMVAMHSHATTGLSTATYQKAIEAGIDVLDTAISSMSQTYGH
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SATETLVAMVEDTERSTGLDMALLEEIAAYFREVRKKYAKFEGALQGIDSRILRAQVPGG
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
MLTNMESQLKEQGASDKLDLVLDEIPRVREDLGFLPLVTPTSQIVGTQAVINVLTGERYK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SLTKETEGVLKGEYGATPAPVNAELQQRVLKGAEPVTCRPADLLTPEMVRLRAELVQKAV
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHHH
AENITLSEDLDDDVLTYALFPQIGLQFLKNRGNADAFEPVPVAVLAASSAPVRVASGPET
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEECCCCE
YTVKVDGQTYVVEVAAGGEISQIQTQGVSQSSASVAPVATAAAPVSHEIKLEMSAPLSGN
EEEEECCCEEEEEEECCCCHHHHHHCCCCCCCCCCCCHHHHCCCCCCEEEEEECCCCCCC
IFKIHVSPGDTVKAGDVVIILEAMKMETEIRAQADGVIARLWVKEGDSVAVGAQLLSLA
EEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHHCCEEEEEEECCCCCEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2454915 [H]