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The map label for this gene is fkpB [H]

Identifier: 119774063

GI number: 119774063

Start: 1119755

End: 1120174

Strand: Direct

Name: fkpB [H]

Synonym: Sama_0926

Alternate gene names: 119774063

Gene position: 1119755-1120174 (Clockwise)

Preceding gene: 119774062

Following gene: 119774064

Centisome position: 26.0

GC content: 57.14

Gene sequence:

>420_bases
ATGAGCCAAAAGTCGTTGCTGTGCCATATGAATATTCTCTTGTCTGACGGTTCTACCGCCGACAGCACCAAGGCGTCGGG
TAAGCCCGCTCGCCTCAATATTGGTGATGGCAGCCTGAGCCCGGCGTTTGAAGCTGAGCTTGGCGCACTGAAGGTCGGTG
ATTCGCACAAGTTCACCCTGCAGCCACAGGATGCCTTTGGTGATGTGAATCCTGATGCGATTCATCATCTCGATCGCAGC
CGCTTCCCTGCCGATATGCAGCTGGAGGCCGGTGTGATTGTCAGTTTTGCAGGCCCCGGTGGCAGCGAAATTCCCGGCAT
TGTCCGTGATGTGGCTGGCGATTCTGTGACGGTCGATCTGAACCATCCTCTGGCCGGTCAGGCCGTGACCTTCGAGCTGG
AAGTGCTGGAGGAGCTCTGA

Upstream 100 bases:

>100_bases
TAACATAGCAGATGCCGCCATCTTTATTGGTGCCGTGCTGATTATTATCGACAGCTTTAAAGCGTCCAGCTCGGATGACA
AGGCCATCAAGGAGTAACAC

Downstream 100 bases:

>100_bases
TGACTGGACAGATGAACATTCTGCTCGCCAATCCACGCGGCTTTTGTGCCGGCGTAGATCGCGCTATCAGCATCGTTGAG
CGTGCTCTTGAGCTGTTCTC

Product: peptidylprolyl isomerase, FKBP-type

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MSQKSLLCHMNILLSDGSTADSTKASGKPARLNIGDGSLSPAFEAELGALKVGDSHKFTLQPQDAFGDVNPDAIHHLDRS
RFPADMQLEAGVIVSFAGPGGSEIPGIVRDVAGDSVTVDLNHPLAGQAVTFELEVLEEL

Sequences:

>Translated_139_residues
MSQKSLLCHMNILLSDGSTADSTKASGKPARLNIGDGSLSPAFEAELGALKVGDSHKFTLQPQDAFGDVNPDAIHHLDRS
RFPADMQLEAGVIVSFAGPGGSEIPGIVRDVAGDSVTVDLNHPLAGQAVTFELEVLEEL
>Mature_138_residues
SQKSLLCHMNILLSDGSTADSTKASGKPARLNIGDGSLSPAFEAELGALKVGDSHKFTLQPQDAFGDVNPDAIHHLDRSR
FPADMQLEAGVIVSFAGPGGSEIPGIVRDVAGDSVTVDLNHPLAGQAVTFELEVLEEL

Specific function: PPIases accelerate the folding of proteins. Substrate specificity carried out with 'Suc-Ala-Xaa-Pro-Phe-4-nitroanilide', where Xaa is the amino acid tested, was found to be Phe > Leu >> Ile > Lys = Ala > Trp > His >> Gln [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786211, Length=136, Percent_Identity=48.5294117647059, Blast_Score=134, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 14549; Mature: 14418

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKSLLCHMNILLSDGSTADSTKASGKPARLNIGDGSLSPAFEAELGALKVGDSHKFTL
CCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEECCCCEEEE
QPQDAFGDVNPDAIHHLDRSRFPADMQLEAGVIVSFAGPGGSEIPGIVRDVAGDSVTVDL
CCCCCCCCCCHHHHHHHHHHCCCCCEEEECCEEEEEECCCCCCCCHHHHHCCCCEEEEEC
NHPLAGQAVTFELEVLEEL
CCCCCCCEEEEEEEEHHCC
>Mature Secondary Structure 
SQKSLLCHMNILLSDGSTADSTKASGKPARLNIGDGSLSPAFEAELGALKVGDSHKFTL
CCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEECCCCEEEE
QPQDAFGDVNPDAIHHLDRSRFPADMQLEAGVIVSFAGPGGSEIPGIVRDVAGDSVTVDL
CCCCCCCCCCHHHHHHHHHHCCCCCEEEECCEEEEEECCCCCCCCHHHHHCCCCEEEEEC
NHPLAGQAVTFELEVLEEL
CCCCCCCEEEEEEEEHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]