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The map label for this gene is cobT

Identifier: 119773899

GI number: 119773899

Start: 945129

End: 946163

Strand: Direct

Name: cobT

Synonym: Sama_0762

Alternate gene names: 119773899

Gene position: 945129-946163 (Clockwise)

Preceding gene: 119773898

Following gene: 119773900

Centisome position: 21.95

GC content: 60.68

Gene sequence:

>1035_bases
ATGTTTGATATAGCTCCCGTCAGCCGCGAACGGGATGAGCAAATCCAGGCGTGCATCGACGATAAAACCAAGCCAAGAGG
TGCACTTGGGGCGCTGGAGCCTCTGGCGGCGCACCTGGCAAGGCTTTTGGGTGAGGCGCCGGAAATTGGCCGGCCTGCCA
TGTTGGTATTTGCCGCCGACCACGGTATTGCCAGTGCCGGTGTATCCATTGCACCGCCGGAGGTAACCGGCCAGATGGTG
GCCAACTTTGCCGCCGGGGGCGCCGCCATCAATGTGTTTTGCCGCCAGCTCGGTTGGCAGCTTGAAATCATCGACGCCGG
TATGCTCAGCGCACCGCCAAGGGAAATGGGCGTGACAGATTGTCGCCTCGGCGCAGGCACGGGCCCCATTCACAAGCGCG
CCGCCATGACCCTTGGACAGGTTGAGCATGGCTTGGCCTTTGGCCGTGAAAGGGTGCGCTCGCACCACGCCGAAGGCACC
AATCTCATCGGACTGGGGGAAATGGGAATAGGCAATACCTCGAGCGCCGCAGCAGTGATGGCAGCCTTGATGGGGCTTGA
AGCCAAAGACTGTGTTGGCCGCGGTACCGGCGTGGACGCGGCCACACTTAAGCGCAAGCAGATGCTGGTGGAGCAGGCGC
TCTTGTTGCACCTGGATATGCTCACCAGCCCGGAGTCTGTCCTTGCCTGTGTGGGCGGCTTTGAAATAGTCGAGATGACC
GGCGCCATCCTCGGAGCGGCTGAGCTGGGGATCCCCGTGTTGGTGGACGGCTTTATTGCCACCACGGCCGCACTCGCAGC
GGTGAAGATGTTCCCCCAAAGCCGTGAATATCTTATCTTTGCTCATCGCTCGGCAGAGCGTGCCCATGGGCTGATGCTGG
CGCATATGGAGGCTGAGCCGTTACTGAGCCTGGATATGCGTCTCGGTGAAGGTACAGGGGCGGCATTGGCCTTGCCACTG
GTGCAGGCAGCGGCCAATTTTTATCGTGAGATGGCGAGCTTCAGCGACGCCGGAATTACAGATGTAACGCCTTAG

Upstream 100 bases:

>100_bases
GCCGCCGCAGGAGTTGCCTGTGGGGGTGATTACTGCCGTGGTTGGCAGTGTGTTTTTCCTGATGCTGCTCTTTGGCCGCA
GGAGTGAATAAGGATATTGG

Downstream 100 bases:

>100_bases
GGCGGGAGCAGTTATGTCGACCTTTAAGCGTGAACTTGAGTTGTTTTTGTTGGCGCTCACCTTTTTTACCCGCATTCCTG
TGCCGGTAAAACTCGATTAC

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MFDIAPVSRERDEQIQACIDDKTKPRGALGALEPLAAHLARLLGEAPEIGRPAMLVFAADHGIASAGVSIAPPEVTGQMV
ANFAAGGAAINVFCRQLGWQLEIIDAGMLSAPPREMGVTDCRLGAGTGPIHKRAAMTLGQVEHGLAFGRERVRSHHAEGT
NLIGLGEMGIGNTSSAAAVMAALMGLEAKDCVGRGTGVDAATLKRKQMLVEQALLLHLDMLTSPESVLACVGGFEIVEMT
GAILGAAELGIPVLVDGFIATTAALAAVKMFPQSREYLIFAHRSAERAHGLMLAHMEAEPLLSLDMRLGEGTGAALALPL
VQAAANFYREMASFSDAGITDVTP

Sequences:

>Translated_344_residues
MFDIAPVSRERDEQIQACIDDKTKPRGALGALEPLAAHLARLLGEAPEIGRPAMLVFAADHGIASAGVSIAPPEVTGQMV
ANFAAGGAAINVFCRQLGWQLEIIDAGMLSAPPREMGVTDCRLGAGTGPIHKRAAMTLGQVEHGLAFGRERVRSHHAEGT
NLIGLGEMGIGNTSSAAAVMAALMGLEAKDCVGRGTGVDAATLKRKQMLVEQALLLHLDMLTSPESVLACVGGFEIVEMT
GAILGAAELGIPVLVDGFIATTAALAAVKMFPQSREYLIFAHRSAERAHGLMLAHMEAEPLLSLDMRLGEGTGAALALPL
VQAAANFYREMASFSDAGITDVTP
>Mature_344_residues
MFDIAPVSRERDEQIQACIDDKTKPRGALGALEPLAAHLARLLGEAPEIGRPAMLVFAADHGIASAGVSIAPPEVTGQMV
ANFAAGGAAINVFCRQLGWQLEIIDAGMLSAPPREMGVTDCRLGAGTGPIHKRAAMTLGQVEHGLAFGRERVRSHHAEGT
NLIGLGEMGIGNTSSAAAVMAALMGLEAKDCVGRGTGVDAATLKRKQMLVEQALLLHLDMLTSPESVLACVGGFEIVEMT
GAILGAAELGIPVLVDGFIATTAALAAVKMFPQSREYLIFAHRSAERAHGLMLAHMEAEPLLSLDMRLGEGTGAALALPL
VQAAANFYREMASFSDAGITDVTP

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family

Homologues:

Organism=Escherichia coli, GI1788300, Length=327, Percent_Identity=38.8379204892966, Blast_Score=209, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBT_SHEAM (A1S3L3)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_926639.1
- ProteinModelPortal:   A1S3L3
- SMR:   A1S3L3
- STRING:   A1S3L3
- GeneID:   4603014
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_0762
- NMPDR:   fig|326297.7.peg.715
- eggNOG:   COG2038
- HOGENOM:   HBG634399
- OMA:   NEMATFS
- PhylomeDB:   A1S3L3
- ProtClustDB:   PRK00105
- HAMAP:   MF_00230
- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846
- Gene3D:   G3DSA:1.10.1610.10
- TIGRFAMs:   TIGR03160

Pfam domain/function: PF02277 DBI_PRT; SSF52733 NN:DBI_PRT

EC number: =2.4.2.21

Molecular weight: Translated: 35836; Mature: 35836

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: ACT_SITE 310-310

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDIAPVSRERDEQIQACIDDKTKPRGALGALEPLAAHLARLLGEAPEIGRPAMLVFAAD
CCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEC
HGIASAGVSIAPPEVTGQMVANFAAGGAAINVFCRQLGWQLEIIDAGMLSAPPREMGVTD
CCHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEECCCCCCCCHHCCCCC
CRLGAGTGPIHKRAAMTLGQVEHGLAFGRERVRSHHAEGTNLIGLGEMGIGNTSSAAAVM
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHH
AALMGLEAKDCVGRGTGVDAATLKRKQMLVEQALLLHLDMLTSPESVLACVGGFEIVEMT
HHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHH
GAILGAAELGIPVLVDGFIATTAALAAVKMFPQSREYLIFAHRSAERAHGLMLAHMEAEP
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHCCEEEEECCCCC
LLSLDMRLGEGTGAALALPLVQAAANFYREMASFSDAGITDVTP
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFDIAPVSRERDEQIQACIDDKTKPRGALGALEPLAAHLARLLGEAPEIGRPAMLVFAAD
CCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEC
HGIASAGVSIAPPEVTGQMVANFAAGGAAINVFCRQLGWQLEIIDAGMLSAPPREMGVTD
CCHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEECCCCCCCCHHCCCCC
CRLGAGTGPIHKRAAMTLGQVEHGLAFGRERVRSHHAEGTNLIGLGEMGIGNTSSAAAVM
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHH
AALMGLEAKDCVGRGTGVDAATLKRKQMLVEQALLLHLDMLTSPESVLACVGGFEIVEMT
HHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHH
GAILGAAELGIPVLVDGFIATTAALAAVKMFPQSREYLIFAHRSAERAHGLMLAHMEAEP
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHCCEEEEECCCCC
LLSLDMRLGEGTGAALALPLVQAAANFYREMASFSDAGITDVTP
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA