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The map label for this gene is fecD [C]

Identifier: 119773898

GI number: 119773898

Start: 944076

End: 945119

Strand: Direct

Name: fecD [C]

Synonym: Sama_0761

Alternate gene names: 119773898

Gene position: 944076-945119 (Clockwise)

Preceding gene: 119773897

Following gene: 119773899

Centisome position: 21.92

GC content: 57.47

Gene sequence:

>1044_bases
GTGACCGCCCTAAAAGCCATGTTAACCCCCCTTGGTCGCCGGGAGCTGATGGTGCTGGCGCTTATTCTGGCCTGTCTGTT
ATCGCCTGTGCTGGCCAGTATTTTTGGTGCCGTGGATATCAGCTTTCGTGAGGCCATGTCGGTCTACCTGCATAGTCTCA
TTGGCGAGCGTCCCACCGATGTGGCCTACCTCGACAGCCGTATCCTGCTGGAGCTGAGGTTGCCGCGCATACTCCTGGCC
TTTGTGTGCGGCGCCGGATTGGCGCTGTCTGGCTGGGCGCTGCAACTGGTGACCCGAAATCCGCTGGCAGACCCTTATCT
TTTTGGGATCAGTGCCGGTGCCAGCCTGGGGGCAATTGTGGTACTCAGCCTTGGAATTACCCATGGGGTACTGCTCGCCA
TCGGTCTGCCGCTGGGGGCCTTTATCGGTGCTAGTGCCTCGGTATTGGTGGTGCTTACCCTCAGTGGCTTTGGGCTGCAA
AGCCAGGTTGAGCGAATGCTGCTTTCCGGGGTCGCCACCTCCTTTTTATTCGGCGCCCTTGGCAGTTTGCTTCTATATTT
TTCAAGCCCCCAGGTAACTGCGTCGGTGATATTCTGGAGTCTGGGCAGCTTTGCCCGTGCAGCATGGGATCTGCTCTGGT
TACCCTGGTTGGTGTTTGGCGGATTTGTGGCCTTTTTGCTGCTGGTCAGGCGCCAGCTTTTTGCACTCAGCGCCGGTGAT
GAAACCGCCCACGCCCTGGGCGTTTCAGTGGCTAAGCTTCGCATTATCAGTTTGCTGATGTGCTCATTGATGACCGCCGT
GCTGGTAGCCAGCTGTGGCGGCATTGGTTTTGTGGGACTGATGATCCCCCACATCGCCAGATTGCTGTTTCCGGGCAGCC
AGTCGCTGCTGATTGTGGCCATGCTGGGTGGGCTTTTTATGGTGTGGGTTGATGTGATGACCCGCAGTTTACTGCCGCCG
CAGGAGTTGCCTGTGGGGGTGATTACTGCCGTGGTTGGCAGTGTGTTTTTCCTGATGCTGCTCTTTGGCCGCAGGAGTGA
ATAA

Upstream 100 bases:

>100_bases
CTACAGTTAAGCCTCATCCCCAGCATGGTCGCCCGCTCATCCATTACTACTATGGCTATAACGGCCGCACCGCCTCCCAA
GAAAAAGAAGAGGTGAGCCT

Downstream 100 bases:

>100_bases
GGATATTGGATGTTTGATATAGCTCCCGTCAGCCGCGAACGGGATGAGCAAATCCAGGCGTGCATCGACGATAAAACCAA
GCCAAGAGGTGCACTTGGGG

Product: iron-compound ABC transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MTALKAMLTPLGRRELMVLALILACLLSPVLASIFGAVDISFREAMSVYLHSLIGERPTDVAYLDSRILLELRLPRILLA
FVCGAGLALSGWALQLVTRNPLADPYLFGISAGASLGAIVVLSLGITHGVLLAIGLPLGAFIGASASVLVVLTLSGFGLQ
SQVERMLLSGVATSFLFGALGSLLLYFSSPQVTASVIFWSLGSFARAAWDLLWLPWLVFGGFVAFLLLVRRQLFALSAGD
ETAHALGVSVAKLRIISLLMCSLMTAVLVASCGGIGFVGLMIPHIARLLFPGSQSLLIVAMLGGLFMVWVDVMTRSLLPP
QELPVGVITAVVGSVFFLMLLFGRRSE

Sequences:

>Translated_347_residues
MTALKAMLTPLGRRELMVLALILACLLSPVLASIFGAVDISFREAMSVYLHSLIGERPTDVAYLDSRILLELRLPRILLA
FVCGAGLALSGWALQLVTRNPLADPYLFGISAGASLGAIVVLSLGITHGVLLAIGLPLGAFIGASASVLVVLTLSGFGLQ
SQVERMLLSGVATSFLFGALGSLLLYFSSPQVTASVIFWSLGSFARAAWDLLWLPWLVFGGFVAFLLLVRRQLFALSAGD
ETAHALGVSVAKLRIISLLMCSLMTAVLVASCGGIGFVGLMIPHIARLLFPGSQSLLIVAMLGGLFMVWVDVMTRSLLPP
QELPVGVITAVVGSVFFLMLLFGRRSE
>Mature_346_residues
TALKAMLTPLGRRELMVLALILACLLSPVLASIFGAVDISFREAMSVYLHSLIGERPTDVAYLDSRILLELRLPRILLAF
VCGAGLALSGWALQLVTRNPLADPYLFGISAGASLGAIVVLSLGITHGVLLAIGLPLGAFIGASASVLVVLTLSGFGLQS
QVERMLLSGVATSFLFGALGSLLLYFSSPQVTASVIFWSLGSFARAAWDLLWLPWLVFGGFVAFLLLVRRQLFALSAGDE
TAHALGVSVAKLRIISLLMCSLMTAVLVASCGGIGFVGLMIPHIARLLFPGSQSLLIVAMLGGLFMVWVDVMTRSLLPPQ
ELPVGVITAVVGSVFFLMLLFGRRSE

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=280, Percent_Identity=36.7857142857143, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790741, Length=313, Percent_Identity=32.2683706070287, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786347, Length=275, Percent_Identity=36.3636363636364, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788004, Length=280, Percent_Identity=34.2857142857143, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786805, Length=288, Percent_Identity=34.375, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786804, Length=341, Percent_Identity=29.9120234604106, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36773; Mature: 36642

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALKAMLTPLGRRELMVLALILACLLSPVLASIFGAVDISFREAMSVYLHSLIGERPTD
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VAYLDSRILLELRLPRILLAFVCGAGLALSGWALQLVTRNPLADPYLFGISAGASLGAIV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEECCCCCCCHHHHCCCCCHHHHHH
VLSLGITHGVLLAIGLPLGAFIGASASVLVVLTLSGFGLQSQVERMLLSGVATSFLFGAL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
GSLLLYFSSPQVTASVIFWSLGSFARAAWDLLWLPWLVFGGFVAFLLLVRRQLFALSAGD
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ETAHALGVSVAKLRIISLLMCSLMTAVLVASCGGIGFVGLMIPHIARLLFPGSQSLLIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
MLGGLFMVWVDVMTRSLLPPQELPVGVITAVVGSVFFLMLLFGRRSE
HHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TALKAMLTPLGRRELMVLALILACLLSPVLASIFGAVDISFREAMSVYLHSLIGERPTD
CHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VAYLDSRILLELRLPRILLAFVCGAGLALSGWALQLVTRNPLADPYLFGISAGASLGAIV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEECCCCCCCHHHHCCCCCHHHHHH
VLSLGITHGVLLAIGLPLGAFIGASASVLVVLTLSGFGLQSQVERMLLSGVATSFLFGAL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
GSLLLYFSSPQVTASVIFWSLGSFARAAWDLLWLPWLVFGGFVAFLLLVRRQLFALSAGD
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ETAHALGVSVAKLRIISLLMCSLMTAVLVASCGGIGFVGLMIPHIARLLFPGSQSLLIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
MLGGLFMVWVDVMTRSLLPPQELPVGVITAVVGSVFFLMLLFGRRSE
HHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]