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The map label for this gene is fpr [H]

Identifier: 119773801

GI number: 119773801

Start: 818702

End: 819484

Strand: Direct

Name: fpr [H]

Synonym: Sama_0663

Alternate gene names: 119773801

Gene position: 818702-819484 (Clockwise)

Preceding gene: 119773800

Following gene: 119773802

Centisome position: 19.01

GC content: 55.43

Gene sequence:

>783_bases
ATGCTGGAACTGCAGCCACAGAGTAGGGGAGGCGATATGTGGGTTGAAGGCCGGGTGTTGCAGCGAAGGGATTGGACCGA
CAAGTTGTTCAGTCTCAGGATTGACGCCAAAATAGCGCCCTTTATCGCGGGCCAGTTTATCAAACTCAGTTTACCCAGCG
AGGATAAGCGCATTGCCCGTGCTTATTCTCTGGTTAACCCTCCCAGAACCGATTATATCGAGGTGCTGGCCGTTGCCGTT
GAAGAGGGCGAGCTCTCTCCAAGGCTGCAGGACTTAAGCCCTGGTGATGTACTTCAGGTTTCGGCCAGTGCAACCGGCTT
TTTAACCTTGAATGAATTACCCGACGCTCCTGCAGCTGGGCGTCAGCTTTGGATGCTGGCCACAGGCACCGCCGTTGGCC
CCTTTATTTCCATGCTTGGCACCGAGGAGCCCTGGCAAAGGTTTGAACACCTGGTGCTTGTGTATGGGGTTCGCCGGGCT
GAGGATTTGGCTTATCTTGACGAGTTGCAAGCCCTGGCAGCAAGCAGGCCCGGACTGCAGCTCATCTTATCGGTTACCCG
GGAGTCAGTACCCGGAGCCATGCAACTGAGGATACCCGATGCGTTGGCCTCTGGCGCGCTCGAAGCTGCCAGCGGCCTTA
CATTGTCTGCCGAGCATTCTCAGGTGATGATTTGTGGTAACCCCGAGATGGTTGCAAGCACCCAGGCATTGTTGCTGGAA
CGTGGTCTTAGTAAAAACCTTCGCAGGGCACCCGGGCAAATCACCGTGGAAAAATACTGGTAA

Upstream 100 bases:

>100_bases
AAGGATTTTGCCCAGAAGATGAATCCACAAAGTAAAGAAGAGAGTGCAGCAGGATAAACGCCTCCGATAAAAAGGGTTTT
TATTTTTTTCTCCCTTGCTT

Downstream 100 bases:

>100_bases
ACACACAAGGAACTCTCCATGAAGCTTTTATGCTCTGCACCTTCGCCTTATTCCCGCATGGTCCGAATCATGGTGCGCTA
CCTGGAATTGGATGTCGAAG

Product: ferredoxin--NADP reductase

Products: NA

Alternate protein names: FNR; DA1; Flavodoxin reductase; FLDR; FLXR; Methyl viologen resistance protein A [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLELQPQSRGGDMWVEGRVLQRRDWTDKLFSLRIDAKIAPFIAGQFIKLSLPSEDKRIARAYSLVNPPRTDYIEVLAVAV
EEGELSPRLQDLSPGDVLQVSASATGFLTLNELPDAPAAGRQLWMLATGTAVGPFISMLGTEEPWQRFEHLVLVYGVRRA
EDLAYLDELQALAASRPGLQLILSVTRESVPGAMQLRIPDALASGALEAASGLTLSAEHSQVMICGNPEMVASTQALLLE
RGLSKNLRRAPGQITVEKYW

Sequences:

>Translated_260_residues
MLELQPQSRGGDMWVEGRVLQRRDWTDKLFSLRIDAKIAPFIAGQFIKLSLPSEDKRIARAYSLVNPPRTDYIEVLAVAV
EEGELSPRLQDLSPGDVLQVSASATGFLTLNELPDAPAAGRQLWMLATGTAVGPFISMLGTEEPWQRFEHLVLVYGVRRA
EDLAYLDELQALAASRPGLQLILSVTRESVPGAMQLRIPDALASGALEAASGLTLSAEHSQVMICGNPEMVASTQALLLE
RGLSKNLRRAPGQITVEKYW
>Mature_260_residues
MLELQPQSRGGDMWVEGRVLQRRDWTDKLFSLRIDAKIAPFIAGQFIKLSLPSEDKRIARAYSLVNPPRTDYIEVLAVAV
EEGELSPRLQDLSPGDVLQVSASATGFLTLNELPDAPAAGRQLWMLATGTAVGPFISMLGTEEPWQRFEHLVLVYGVRRA
EDLAYLDELQALAASRPGLQLILSVTRESVPGAMQLRIPDALASGALEAASGLTLSAEHSQVMICGNPEMVASTQALLLE
RGLSKNLRRAPGQITVEKYW

Specific function: Transports electrons between flavodoxin or ferredoxin and NADPH. Involved in the reductive activation of cobalamin- independent methionine synthase, pyruvate formate lyase and anaerobic ribonucleotide reductase. Also protects against superoxide radicals d

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790359, Length=249, Percent_Identity=47.3895582329317, Blast_Score=224, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 28461; Mature: 28461

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLELQPQSRGGDMWVEGRVLQRRDWTDKLFSLRIDAKIAPFIAGQFIKLSLPSEDKRIAR
CCCCCCCCCCCCEEEECEEECCCCCCHHHEEEEECCEECHHHCCCEEEEECCCCHHHHHH
AYSLVNPPRTDYIEVLAVAVEEGELSPRLQDLSPGDVLQVSASATGFLTLNELPDAPAAG
HHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCC
RQLWMLATGTAVGPFISMLGTEEPWQRFEHLVLVYGVRRAEDLAYLDELQALAASRPGLQ
CEEEEEEECCHHHHHHHHHCCCCHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LILSVTRESVPGAMQLRIPDALASGALEAASGLTLSAEHSQVMICGNPEMVASTQALLLE
HHHHHHHHCCCCEEEEECCHHHHHCCHHHHCCCEEECCCCEEEEECCCCHHHHHHHHHHH
RGLSKNLRRAPGQITVEKYW
HHHHHHHHHCCCEEEEEECC
>Mature Secondary Structure
MLELQPQSRGGDMWVEGRVLQRRDWTDKLFSLRIDAKIAPFIAGQFIKLSLPSEDKRIAR
CCCCCCCCCCCCEEEECEEECCCCCCHHHEEEEECCEECHHHCCCEEEEECCCCHHHHHH
AYSLVNPPRTDYIEVLAVAVEEGELSPRLQDLSPGDVLQVSASATGFLTLNELPDAPAAG
HHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCC
RQLWMLATGTAVGPFISMLGTEEPWQRFEHLVLVYGVRRAEDLAYLDELQALAASRPGLQ
CEEEEEEECCHHHHHHHHHCCCCHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LILSVTRESVPGAMQLRIPDALASGALEAASGLTLSAEHSQVMICGNPEMVASTQALLLE
HHHHHHHHCCCCEEEEECCHHHHHCCHHHHCCCEEECCCCEEEEECCCCHHHHHHHHHHH
RGLSKNLRRAPGQITVEKYW
HHHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8449868; 8346018; 9278503; 1400248; 2834327; 7961651; 9149148 [H]