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The map label for this gene is murB [H]

Identifier: 119773337

GI number: 119773337

Start: 229927

End: 230940

Strand: Direct

Name: murB [H]

Synonym: Sama_0196

Alternate gene names: 119773337

Gene position: 229927-230940 (Clockwise)

Preceding gene: 119773335

Following gene: 119773338

Centisome position: 5.34

GC content: 50.59

Gene sequence:

>1014_bases
ATGCCTGTTTCTCTCAAGTCCTACAACACCTTTGGTATCGATCATCATTGCGCTGAGCTTATCGAAATAGCTGACGCAGC
TGAGTTGCCAGCAATTATCCGTACCCTGGACGAGCGTGATCAGTCTTACTTTATCCTCGGTGGTGGCAGCAATGTGGTAC
TGACATCGGATCTCGATACCACAGTGCTGAGAATGGTAAATAAAGGAATTGAGGTAGCTGAGGACGATGCTTCCTGGCAT
TTAAGTGTGGCCGCCGGCGAAAACTGGCATCAATTGGTGAGCTGGACCCTTGAAAACCAGATGCCGGGACTTGAGAATCT
GGCGCTTATTCCGGGTACTGTTGGCGCGGCTCCCATCCAGAACATAGGCGCCTACGGTGTTGAGCTGATGGATATCTGCG
AGTGGGTTGAGTATTTGTCGCTGCCAGATTGCGTGACTGTCAGGCTGACCGCCGCAGAGTGCCGGTTCGACTACCGTGAT
TCCATTTTTAAACACGATCTTAAGGGTAAAGCGATTATTACCCGGGTCGGTTTCAACTTACCTAAGATGTGGCAACCTAA
GCTCAATTACGGCCCGCTGGCAGAGTTTGATACAGATACTGTGACGCCCGAGATGATCTACGAGCGTGTGATTGCAGTGC
GTTCAGAGAAGCTGCCCGATCCTGCCAAATTAGGTAACGCTGGCAGCTTTTTCAAGAATCCTATCATTGATGCAGCATCC
TTTGCCGCCATCGTAAAACAGTATCCGGACGCTGTGGCCTATGCCCTGGAAGATGGCCGAATGAAACTGGCTGCCGGCTG
GCTTATTGATAAGGCTGGCTTAAAAGGCTTTCGTCTTGGCGACGCCGGGGTACATGATAAACAGGCGTTGGTGCTGGTTA
ATTTCGGCGCTGCCACTGGTAAAGATATCCTGAAGCTCGCCAAACATGTCATCAATGAGGTGCATACGCGCTTTGGTGTG
CAGCTTGAACCTGAGCCCAATGTGATGGGTCGATTATCACTCTTAACCGAATAA

Upstream 100 bases:

>100_bases
TCAAATGCAGTTCCCACGGGTTTGGCAGTTTCTGTTTCTCGCTGATGCGTTGAATGCCACCCTTGGTTACAATGGCCTTT
TATTCGTGGCGGAAAGCGGT

Downstream 100 bases:

>100_bases
CTCTAAACAGGGAACTGCAAATGGAACAGTGGCAACGTAAACGCGACATTATTGCGATGCTGTCAACGCAGGAGTTTGTG
TCAGGCGAAGCCCTTGCCGA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MPVSLKSYNTFGIDHHCAELIEIADAAELPAIIRTLDERDQSYFILGGGSNVVLTSDLDTTVLRMVNKGIEVAEDDASWH
LSVAAGENWHQLVSWTLENQMPGLENLALIPGTVGAAPIQNIGAYGVELMDICEWVEYLSLPDCVTVRLTAAECRFDYRD
SIFKHDLKGKAIITRVGFNLPKMWQPKLNYGPLAEFDTDTVTPEMIYERVIAVRSEKLPDPAKLGNAGSFFKNPIIDAAS
FAAIVKQYPDAVAYALEDGRMKLAAGWLIDKAGLKGFRLGDAGVHDKQALVLVNFGAATGKDILKLAKHVINEVHTRFGV
QLEPEPNVMGRLSLLTE

Sequences:

>Translated_337_residues
MPVSLKSYNTFGIDHHCAELIEIADAAELPAIIRTLDERDQSYFILGGGSNVVLTSDLDTTVLRMVNKGIEVAEDDASWH
LSVAAGENWHQLVSWTLENQMPGLENLALIPGTVGAAPIQNIGAYGVELMDICEWVEYLSLPDCVTVRLTAAECRFDYRD
SIFKHDLKGKAIITRVGFNLPKMWQPKLNYGPLAEFDTDTVTPEMIYERVIAVRSEKLPDPAKLGNAGSFFKNPIIDAAS
FAAIVKQYPDAVAYALEDGRMKLAAGWLIDKAGLKGFRLGDAGVHDKQALVLVNFGAATGKDILKLAKHVINEVHTRFGV
QLEPEPNVMGRLSLLTE
>Mature_336_residues
PVSLKSYNTFGIDHHCAELIEIADAAELPAIIRTLDERDQSYFILGGGSNVVLTSDLDTTVLRMVNKGIEVAEDDASWHL
SVAAGENWHQLVSWTLENQMPGLENLALIPGTVGAAPIQNIGAYGVELMDICEWVEYLSLPDCVTVRLTAAECRFDYRDS
IFKHDLKGKAIITRVGFNLPKMWQPKLNYGPLAEFDTDTVTPEMIYERVIAVRSEKLPDPAKLGNAGSFFKNPIIDAASF
AAIVKQYPDAVAYALEDGRMKLAAGWLIDKAGLKGFRLGDAGVHDKQALVLVNFGAATGKDILKLAKHVINEVHTRFGVQ
LEPEPNVMGRLSLLTE

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=330, Percent_Identity=50.3030303030303, Blast_Score=333, Evalue=1e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 36993; Mature: 36862

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVSLKSYNTFGIDHHCAELIEIADAAELPAIIRTLDERDQSYFILGGGSNVVLTSDLDT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCHH
TVLRMVNKGIEVAEDDASWHLSVAAGENWHQLVSWTLENQMPGLENLALIPGTVGAAPIQ
HHHHHHHCCCCEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHH
NIGAYGVELMDICEWVEYLSLPDCVTVRLTAAECRFDYRDSIFKHDLKGKAIITRVGFNL
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHCCCHHHHHHHHCCCCCEEEEEECCCC
PKMWQPKLNYGPLAEFDTDTVTPEMIYERVIAVRSEKLPDPAKLGNAGSFFKNPIIDAAS
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHCCCHHHHH
FAAIVKQYPDAVAYALEDGRMKLAAGWLIDKAGLKGFRLGDAGVHDKQALVLVNFGAATG
HHHHHHHCCHHHEEHHCCCCEEEEECEEEECCCCCEEEECCCCCCCCCEEEEEEECCCCC
KDILKLAKHVINEVHTRFGVQLEPEPNVMGRLSLLTE
HHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHCC
>Mature Secondary Structure 
PVSLKSYNTFGIDHHCAELIEIADAAELPAIIRTLDERDQSYFILGGGSNVVLTSDLDT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCHH
TVLRMVNKGIEVAEDDASWHLSVAAGENWHQLVSWTLENQMPGLENLALIPGTVGAAPIQ
HHHHHHHCCCCEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHH
NIGAYGVELMDICEWVEYLSLPDCVTVRLTAAECRFDYRDSIFKHDLKGKAIITRVGFNL
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHCCCHHHHHHHHCCCCCEEEEEECCCC
PKMWQPKLNYGPLAEFDTDTVTPEMIYERVIAVRSEKLPDPAKLGNAGSFFKNPIIDAAS
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHCCCHHHHH
FAAIVKQYPDAVAYALEDGRMKLAAGWLIDKAGLKGFRLGDAGVHDKQALVLVNFGAATG
HHHHHHHCCHHHEEHHCCCCEEEEECEEEECCCCCEEEECCCCCCCCCEEEEEEECCCCC
KDILKLAKHVINEVHTRFGVQLEPEPNVMGRLSLLTE
HHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]