BacMap

Definition	Nocardioides sp. JS614 chromosome, complete genome.
Accession	NC_008699
Length	4,985,871

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The map label for this gene is fabG2 [H]

Identifier: 119718060

GI number: 119718060

Start: 4061142

End: 4061930

Strand: Reverse

Name: fabG2 [H]

Synonym: Noca_3840

Alternate gene names: 119718060

Gene position: 4061930-4061142 (Counterclockwise)

Preceding gene: 119718061

Following gene: 119718057

Centisome position: 81.47

GC content: 71.23

Gene sequence:

>789_bases
ATGCTCGCGCGCATGGACATCAACGGAGCCAGTGCCATCGTCACGGGTGGGGCGTCGGGCATCGGCGCGGCCGCCGCTCG
TCAGCTCGCCGAGAAGGGCGCGGTCGTCGTGGTCGCCGACCTGCAGGCCGACAAGGGCGAGGCGCTCGCCCAGGAGATCG
GGGGCGTCTTCGCCCGGGTCGACGTCACCGACACCGACCAGATCCGCGCGGCCGTCGAGGCCGCCGCCCAGATCGCCCCG
CTGCGCGCGTGCGTCAACTCCGCCGGCATCGGCTGGGCGCAGCGCACCATCGGCCGCGACGGCGAGTTCGACTCCGCGCA
CGACCTGGAAGCCTTCCGCAAGGTGATCGCGATCAACCTGATCGGCACCTTCGACATGGTCCGGCTCGCCGCGACCGCCA
TGAGCCGCAACGAGCCGGACCAGGACGGCTGTCGCGGCGCGATCGTCAACCTCGCCAGCGTGGCCGCCTTCGACGGCCAG
ATCGGGCAGGCGTCGTACTCCGCCTCCAAGGGCGGGGTCGTCGGCATGACCCTGCCCGTCGCCCGGGATCTCTCCGCCGC
CGGCATCAGGCTCAACACGATCGCTCCGGGCCTGATCGACACCCCGATCTACGGCGAGGGCGAGGCCGCGGAGGCGTTCA
AGGCCAAGCTCGGCGAGAGCGTGCTGTTCCCCAAGCGCCTCGGCGTGCCGGACGAGCTGGCCAGCATGGTCGTCGAGTGC
ATCACCAACAGCTACCTGAACGCCGAGGTGATCCGCGTCGACGGCGGCATCCGGATGCCCCCCAAGTAG

Upstream 100 bases:

>100_bases
GCCCCGCCGTCATCGTCGCCCGGGGCACCACCGTGCTCTGAGCGGCGAACCCGGCGACCGCTCGGACCCGCACCGTGACA
GTCCCACTGTGAGCATGGTT

Downstream 100 bases:

>100_bases
GCGCCGACCAGCCTGCGGTGGGGTCGTGTGCCTGAGGACGCGCCATGGCGCGTGCTCAGGCACACGACCCGGAGGGGCCC
CGGCCAGAGCTAGAGCTCGA

Product: short-chain dehydrogenase/reductase SDR

Products: 3-oxoacyl-CoA; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MLARMDINGASAIVTGGASGIGAAAARQLAEKGAVVVVADLQADKGEALAQEIGGVFARVDVTDTDQIRAAVEAAAQIAP
LRACVNSAGIGWAQRTIGRDGEFDSAHDLEAFRKVIAINLIGTFDMVRLAATAMSRNEPDQDGCRGAIVNLASVAAFDGQ
IGQASYSASKGGVVGMTLPVARDLSAAGIRLNTIAPGLIDTPIYGEGEAAEAFKAKLGESVLFPKRLGVPDELASMVVEC
ITNSYLNAEVIRVDGGIRMPPK

Sequences:

>Translated_262_residues
MLARMDINGASAIVTGGASGIGAAAARQLAEKGAVVVVADLQADKGEALAQEIGGVFARVDVTDTDQIRAAVEAAAQIAP
LRACVNSAGIGWAQRTIGRDGEFDSAHDLEAFRKVIAINLIGTFDMVRLAATAMSRNEPDQDGCRGAIVNLASVAAFDGQ
IGQASYSASKGGVVGMTLPVARDLSAAGIRLNTIAPGLIDTPIYGEGEAAEAFKAKLGESVLFPKRLGVPDELASMVVEC
ITNSYLNAEVIRVDGGIRMPPK
>Mature_262_residues
MLARMDINGASAIVTGGASGIGAAAARQLAEKGAVVVVADLQADKGEALAQEIGGVFARVDVTDTDQIRAAVEAAAQIAP
LRACVNSAGIGWAQRTIGRDGEFDSAHDLEAFRKVIAINLIGTFDMVRLAATAMSRNEPDQDGCRGAIVNLASVAAFDGQ
IGQASYSASKGGVVGMTLPVARDLSAAGIRLNTIAPGLIDTPIYGEGEAAEAFKAKLGESVLFPKRLGVPDELASMVVEC
ITNSYLNAEVIRVDGGIRMPPK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4758504, Length=260, Percent_Identity=48.8461538461538, Blast_Score=222, Evalue=3e-58,
Organism=Homo sapiens, GI83715985, Length=261, Percent_Identity=46.7432950191571, Blast_Score=201, Evalue=5e-52,
Organism=Homo sapiens, GI15277342, Length=270, Percent_Identity=32.2222222222222, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI59889578, Length=182, Percent_Identity=33.5164835164835, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=29.718875502008, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI31542939, Length=269, Percent_Identity=28.6245353159851, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI19923817, Length=271, Percent_Identity=27.3062730627306, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI5031737, Length=258, Percent_Identity=28.6821705426357, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI32483357, Length=273, Percent_Identity=28.2051282051282, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI166795268, Length=219, Percent_Identity=26.9406392694064, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI4504505, Length=211, Percent_Identity=30.3317535545024, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI33667109, Length=202, Percent_Identity=29.7029702970297, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI2367175, Length=259, Percent_Identity=33.2046332046332, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787335, Length=261, Percent_Identity=29.8850574712644, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=31.3953488372093, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786812, Length=263, Percent_Identity=30.4182509505703, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1787905, Length=261, Percent_Identity=29.1187739463602, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1789208, Length=264, Percent_Identity=29.1666666666667, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789378, Length=260, Percent_Identity=27.6923076923077, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789057, Length=240, Percent_Identity=28.3333333333333, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082160, Length=262, Percent_Identity=28.2442748091603, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI2367365, Length=235, Percent_Identity=29.7872340425532, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788459, Length=257, Percent_Identity=26.0700389105058, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=262, Percent_Identity=46.5648854961832, Blast_Score=222, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI25147288, Length=264, Percent_Identity=30.6818181818182, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17555706, Length=259, Percent_Identity=31.2741312741313, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=264, Percent_Identity=29.9242424242424, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=275, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=273, Percent_Identity=28.2051282051282, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=269, Percent_Identity=27.1375464684015, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=272, Percent_Identity=27.2058823529412, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=258, Percent_Identity=26.7441860465116, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=25.4681647940075, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=213, Percent_Identity=26.7605633802817, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=273, Percent_Identity=27.4725274725275, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=272, Percent_Identity=27.5735294117647, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=261, Percent_Identity=27.9693486590038, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320089, Length=207, Percent_Identity=27.536231884058, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17737361, Length=258, Percent_Identity=51.5503875968992, Blast_Score=239, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24639444, Length=258, Percent_Identity=33.7209302325581, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=28.6274509803922, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI23397609, Length=202, Percent_Identity=30.1980198019802, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI161076371, Length=239, Percent_Identity=27.6150627615063, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644339, Length=224, Percent_Identity=29.4642857142857, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21355319, Length=263, Percent_Identity=28.1368821292776, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI22024069, Length=218, Percent_Identity=27.0642201834862, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=27.1317829457364, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24665243, Length=251, Percent_Identity=25.8964143426295, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI19921754, Length=220, Percent_Identity=25.9090909090909, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.35

Molecular weight: Translated: 26965; Mature: 26965

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLARMDINGASAIVTGGASGIGAAAARQLAEKGAVVVVADLQADKGEALAQEIGGVFARV
CCEEECCCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCEEEEE
DVTDTDQIRAAVEAAAQIAPLRACVNSAGIGWAQRTIGRDGEFDSAHDLEAFRKVIAINL
ECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
IGTFDMVRLAATAMSRNEPDQDGCRGAIVNLASVAAFDGQIGQASYSASKGGVVGMTLPV
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECHH
ARDLSAAGIRLNTIAPGLIDTPIYGEGEAAEAFKAKLGESVLFPKRLGVPDELASMVVEC
HHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHH
ITNSYLNAEVIRVDGGIRMPPK
HHCCCCCEEEEEECCCEECCCC
>Mature Secondary Structure
MLARMDINGASAIVTGGASGIGAAAARQLAEKGAVVVVADLQADKGEALAQEIGGVFARV
CCEEECCCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCEEEEE
DVTDTDQIRAAVEAAAQIAPLRACVNSAGIGWAQRTIGRDGEFDSAHDLEAFRKVIAINL
ECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
IGTFDMVRLAATAMSRNEPDQDGCRGAIVNLASVAAFDGQIGQASYSASKGGVVGMTLPV
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECHH
ARDLSAAGIRLNTIAPGLIDTPIYGEGEAAEAFKAKLGESVLFPKRLGVPDELASMVVEC
HHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHH
ITNSYLNAEVIRVDGGIRMPPK
HHCCCCCEEEEEECCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-3-hydroxyacyl-CoA; NAD+

Specific reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]