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The map label for this gene is hflX [H]

Identifier: 119718057

GI number: 119718057

Start: 4056426

End: 4057907

Strand: Reverse

Name: hflX [H]

Synonym: Noca_3837

Alternate gene names: 119718057

Gene position: 4057907-4056426 (Counterclockwise)

Preceding gene: 119718060

Following gene: 119718055

Centisome position: 81.39

GC content: 71.05

Gene sequence:

>1482_bases
ATGACGAACGCACCTGACCTCAACTCCTTCAGCCTCGACGACGAGCTCGCGGCCACCGAGGACTGGGAGGACGACGACTT
CCGGTCCGGCTATGTCGACGAGCCCGACCCGGAGGAGCCCACGACCGGCGACCTCGACCTCGCGGAGCGGCACGAGCTGC
GCCGCGTGGCGGGGCTGCGCACCGAGCTCGAGGACATCACCGAGGTCGAGTACCGCCAGCTCCGGCTGGAGCGGGTGGTG
CTCGTCGGGGTCTGGACCGAGGGGTCCGTCGAGGACGCGGAGAACTCCATGGCCGAGCTCGCGCTGCTCGCCGAGACCGC
CGGCTCAGAGGTGCTCGACGCGATCTACCAGCGCCGCCAGAAGCCCGACCCCGCCACCTACATCGGCCGGGGCAAGGTCG
ACGGCCTGCGCGAGATCGTGCAGGCCACCGGCGCCGACACCGTCATCTGCGACGGCGAGCTGGCGCCCAGCCAGCTGCGC
AACCTCGAGGACCGGCTCAAGGTCAAGGTCGTCGACCGGACCGCCCTGATCCTCGACATCTTCGCCCAGCACGCGAAGTC
CAAGGAGGGCCAGGCGCAGGTCGAGCTGGCCCAGCTCAACTACCTCAAGCAGCGCCTGCGCGGCTGGGGTGGCAACCTCT
CGCGCCAGGTCGGCGGTCGCGCCGCGGGTGGCGTCGGCATCGGCGGCCGCGGCCCCGGTGAGACCAAGATCGAGACCGAC
CGCCGCCGGATCAACACCAAGATCGCCAAGCTCCGCCGCGAGCTGAAGGAGATGAAGGGGACCCGCGACACCAAGCGCCA
GGAGCGGCGCCGCCACCACATCCCCAGCGTCTCGATCGCCGGCTACACCAACGCCGGCAAGTCCTCGCTGCTCAACCGGC
TCACCGACGCCGGAGTCCTCGTGGAGGATGCGCTGTTCGCGACGCTCGACCCGACGACGCGTCGTACGACGACCGCCGAC
GGGCGGGTCTACACGATGAGCGACACCGTCGGCTTCGTGCGACACCTGCCGCACCAGCTGGTCGAGGCGTTCCGCTCGAC
GCTGGAGGAGGTCGCCGACGCCGACCTGATCCTGCACGTGGTCGACGGCTCGCACCCCGACCCGGAGGGCCAGCTCACCG
CGGTCCGCGAGGTGTTCGCCGAGATCGGCGCCTCCCAGGTGCCCGAGCTCGTGGTCATCAACAAGGCCGACGCCGCCGAC
CCGATGGTGATCGCGCGGCTGCGCCAGCGCGAGCCGCACTCCGTGGTCGTGTCGGCGAAGACCGGCGAGGGCGTCGCCGA
GGCGCTGCGGGTGATCGAGGGTGAGCTGCCCCGCCCCGGCGTGGAGTTCAAGGCGTTGCTGCCCTACGAGCGCGGTGACC
TGATCAACCGGCTGCACCAGCACGGCGAGATCGACTCGATGGAGCACACCGGCGAGGGCACCATCGTGGTCGGCCGGGCC
AACGAGGACCTGGCCGGCGAGCTGGCGGCGTACGCCGTCTGA

Upstream 100 bases:

>100_bases
TCCGGGAGGTTCGTCACCGGCTCAACGTACTGCCCGGCCGGACGGCGCGTTCGTTATCGGCTCGCGCGGTTCAGGGCTGC
GAACGTACCCTTGGGGGCGT

Downstream 100 bases:

>100_bases
GCGGCCGCGCCGTCAGGTGGGCTGCCCGGCGGGGGTCCACTCCGGGCGCGGGCCGGTGATCTGGTCGAACTCGAGCTCGA
GGTCACGCTCGACGGAGGCG

Product: HSR1-like GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MTNAPDLNSFSLDDELAATEDWEDDDFRSGYVDEPDPEEPTTGDLDLAERHELRRVAGLRTELEDITEVEYRQLRLERVV
LVGVWTEGSVEDAENSMAELALLAETAGSEVLDAIYQRRQKPDPATYIGRGKVDGLREIVQATGADTVICDGELAPSQLR
NLEDRLKVKVVDRTALILDIFAQHAKSKEGQAQVELAQLNYLKQRLRGWGGNLSRQVGGRAAGGVGIGGRGPGETKIETD
RRRINTKIAKLRRELKEMKGTRDTKRQERRRHHIPSVSIAGYTNAGKSSLLNRLTDAGVLVEDALFATLDPTTRRTTTAD
GRVYTMSDTVGFVRHLPHQLVEAFRSTLEEVADADLILHVVDGSHPDPEGQLTAVREVFAEIGASQVPELVVINKADAAD
PMVIARLRQREPHSVVVSAKTGEGVAEALRVIEGELPRPGVEFKALLPYERGDLINRLHQHGEIDSMEHTGEGTIVVGRA
NEDLAGELAAYAV

Sequences:

>Translated_493_residues
MTNAPDLNSFSLDDELAATEDWEDDDFRSGYVDEPDPEEPTTGDLDLAERHELRRVAGLRTELEDITEVEYRQLRLERVV
LVGVWTEGSVEDAENSMAELALLAETAGSEVLDAIYQRRQKPDPATYIGRGKVDGLREIVQATGADTVICDGELAPSQLR
NLEDRLKVKVVDRTALILDIFAQHAKSKEGQAQVELAQLNYLKQRLRGWGGNLSRQVGGRAAGGVGIGGRGPGETKIETD
RRRINTKIAKLRRELKEMKGTRDTKRQERRRHHIPSVSIAGYTNAGKSSLLNRLTDAGVLVEDALFATLDPTTRRTTTAD
GRVYTMSDTVGFVRHLPHQLVEAFRSTLEEVADADLILHVVDGSHPDPEGQLTAVREVFAEIGASQVPELVVINKADAAD
PMVIARLRQREPHSVVVSAKTGEGVAEALRVIEGELPRPGVEFKALLPYERGDLINRLHQHGEIDSMEHTGEGTIVVGRA
NEDLAGELAAYAV
>Mature_492_residues
TNAPDLNSFSLDDELAATEDWEDDDFRSGYVDEPDPEEPTTGDLDLAERHELRRVAGLRTELEDITEVEYRQLRLERVVL
VGVWTEGSVEDAENSMAELALLAETAGSEVLDAIYQRRQKPDPATYIGRGKVDGLREIVQATGADTVICDGELAPSQLRN
LEDRLKVKVVDRTALILDIFAQHAKSKEGQAQVELAQLNYLKQRLRGWGGNLSRQVGGRAAGGVGIGGRGPGETKIETDR
RRINTKIAKLRRELKEMKGTRDTKRQERRRHHIPSVSIAGYTNAGKSSLLNRLTDAGVLVEDALFATLDPTTRRTTTADG
RVYTMSDTVGFVRHLPHQLVEAFRSTLEEVADADLILHVVDGSHPDPEGQLTAVREVFAEIGASQVPELVVINKADAADP
MVIARLRQREPHSVVVSAKTGEGVAEALRVIEGELPRPGVEFKALLPYERGDLINRLHQHGEIDSMEHTGEGTIVVGRAN
EDLAGELAAYAV

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=201, Percent_Identity=38.8059701492537, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI310124267, Length=201, Percent_Identity=38.8059701492537, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI310124171, Length=201, Percent_Identity=38.8059701492537, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI310124169, Length=201, Percent_Identity=38.8059701492537, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI310133118, Length=225, Percent_Identity=38.2222222222222, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI310133116, Length=209, Percent_Identity=38.2775119617225, Blast_Score=125, Evalue=1e-28,
Organism=Escherichia coli, GI1790615, Length=406, Percent_Identity=42.3645320197044, Blast_Score=289, Evalue=3e-79,
Organism=Caenorhabditis elegans, GI17561038, Length=292, Percent_Identity=33.5616438356164, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24650079, Length=359, Percent_Identity=30.6406685236769, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 54196; Mature: 54065

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNAPDLNSFSLDDELAATEDWEDDDFRSGYVDEPDPEEPTTGDLDLAERHELRRVAGLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
TELEDITEVEYRQLRLERVVLVGVWTEGSVEDAENSMAELALLAETAGSEVLDAIYQRRQ
HHHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
KPDPATYIGRGKVDGLREIVQATGADTVICDGELAPSQLRNLEDRLKVKVVDRTALILDI
CCCCCCEECCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHCHHHHHEEEEEHHHHHHHHH
FAQHAKSKEGQAQVELAQLNYLKQRLRGWGGNLSRQVGGRAAGGVGIGGRGPGETKIETD
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHH
RRRINTKIAKLRRELKEMKGTRDTKRQERRRHHIPSVSIAGYTNAGKSSLLNRLTDAGVL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHCCHH
VEDALFATLDPTTRRTTTADGRVYTMSDTVGFVRHLPHQLVEAFRSTLEEVADADLILHV
HHHHHHHHCCCCCCCEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
VDGSHPDPEGQLTAVREVFAEIGASQVPELVVINKADAADPMVIARLRQREPHSVVVSAK
ECCCCCCCCCHHHHHHHHHHHCCHHHCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEEEC
TGEGVAEALRVIEGELPRPGVEFKALLPYERGDLINRLHQHGEIDSMEHTGEGTIVVGRA
CCCHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECC
NEDLAGELAAYAV
CCCHHHHHHHHCC
>Mature Secondary Structure 
TNAPDLNSFSLDDELAATEDWEDDDFRSGYVDEPDPEEPTTGDLDLAERHELRRVAGLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
TELEDITEVEYRQLRLERVVLVGVWTEGSVEDAENSMAELALLAETAGSEVLDAIYQRRQ
HHHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
KPDPATYIGRGKVDGLREIVQATGADTVICDGELAPSQLRNLEDRLKVKVVDRTALILDI
CCCCCCEECCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHCHHHHHEEEEEHHHHHHHHH
FAQHAKSKEGQAQVELAQLNYLKQRLRGWGGNLSRQVGGRAAGGVGIGGRGPGETKIETD
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHH
RRRINTKIAKLRRELKEMKGTRDTKRQERRRHHIPSVSIAGYTNAGKSSLLNRLTDAGVL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHCCHH
VEDALFATLDPTTRRTTTADGRVYTMSDTVGFVRHLPHQLVEAFRSTLEEVADADLILHV
HHHHHHHHCCCCCCCEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
VDGSHPDPEGQLTAVREVFAEIGASQVPELVVINKADAADPMVIARLRQREPHSVVVSAK
ECCCCCCCCCHHHHHHHHHHHCCHHHCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEEEC
TGEGVAEALRVIEGELPRPGVEFKALLPYERGDLINRLHQHGEIDSMEHTGEGTIVVGRA
CCCHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECC
NEDLAGELAAYAV
CCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]