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The map label for this gene is bhbA [H]

Identifier: 119717813

GI number: 119717813

Start: 3809768

End: 3810199

Strand: Reverse

Name: bhbA [H]

Synonym: Noca_3591

Alternate gene names: 119717813

Gene position: 3810199-3809768 (Counterclockwise)

Preceding gene: 119717815

Following gene: 119717812

Centisome position: 76.42

GC content: 73.38

Gene sequence:

>432_bases
ATGACGTCGACCACACCCTCGGGGGGCCCGGCCGGCCCGTCGCCGCGGATCCGGATCGTGGTCGGCAAGCCCGGCCTCGA
CGGCCACGACCGGGGCGCCAAGATCGTCGCCCGCGCGCTGCGGGACGCCGGCCACGAGGTGGTGTACACCGGCCTGCACC
AGACCCCGGAGCAGATCGTGGAGACGGCGATCCAGGAGGACGCCGACCTGATCGGCCTCTCGGTCCTCTCCGGCGCGCAC
ATGACCCTGTTCCGGCGGCTGCTCGAGCTGCTCCGGGAGCGGGACGCGGCCGACATCGTGGTCTTCGGGGGCGGGATCAT
CCCCGAGGAGGACATCCCGGTGCTGGAGGAGCTCGGCGTCGCCAAGGTGTTCACCCCCGGCGCGGCGACCGGCGAGATCA
CCGGCTGGGTCGCGGAGCACTTCGCCGGCTGA

Upstream 100 bases:

>100_bases
GAACCGGGTACTTGAACCCGTTCGGGCGGGGAACGGGGTGGCGGAGTGGGCAGGGTCACGCGTGCCTCCGGCGCGGTTCG
GGGTGGGTTAACCTGCGGAC

Downstream 100 bases:

>100_bases
GGGTTACCGACGAGTCGTATGCCACGCGTCACGTCCGGCCGCCCTCGTCGTACCCGCGGGGTCCGGACTAGGGTGCCCGA
GGACACCCGAGCGACATCCC

Product: cobalamin B12-binding domain-containing protein

Products: NA

Alternate protein names: MCM [H]

Number of amino acids: Translated: 143; Mature: 142

Protein sequence:

>143_residues
MTSTTPSGGPAGPSPRIRIVVGKPGLDGHDRGAKIVARALRDAGHEVVYTGLHQTPEQIVETAIQEDADLIGLSVLSGAH
MTLFRRLLELLRERDAADIVVFGGGIIPEEDIPVLEELGVAKVFTPGAATGEITGWVAEHFAG

Sequences:

>Translated_143_residues
MTSTTPSGGPAGPSPRIRIVVGKPGLDGHDRGAKIVARALRDAGHEVVYTGLHQTPEQIVETAIQEDADLIGLSVLSGAH
MTLFRRLLELLRERDAADIVVFGGGIIPEEDIPVLEELGVAKVFTPGAATGEITGWVAEHFAG
>Mature_142_residues
TSTTPSGGPAGPSPRIRIVVGKPGLDGHDRGAKIVARALRDAGHEVVYTGLHQTPEQIVETAIQEDADLIGLSVLSGAHM
TLFRRLLELLRERDAADIVVFGGGIIPEEDIPVLEELGVAKVFTPGAATGEITGWVAEHFAG

Specific function: Catalyzes the interconversion of succinyl-CoA and methylmalonyl-CoA during the polyhydroxyalkanoate degradation pathway [H]

COG id: COG2185

COG function: function code I; Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 B12-binding domain [H]

Homologues:

Organism=Homo sapiens, GI156105689, Length=112, Percent_Identity=41.9642857142857, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI1789284, Length=112, Percent_Identity=42.8571428571429, Blast_Score=97, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI25144500, Length=110, Percent_Identity=43.6363636363636, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006159
- InterPro:   IPR016176
- InterPro:   IPR014348
- InterPro:   IPR006158
- InterPro:   IPR006099
- InterPro:   IPR006098 [H]

Pfam domain/function: PF02310 B12-binding; PF01642 MM_CoA_mutase [H]

EC number: =5.4.99.2 [H]

Molecular weight: Translated: 15024; Mature: 14893

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTTPSGGPAGPSPRIRIVVGKPGLDGHDRGAKIVARALRDAGHEVVYTGLHQTPEQIV
CCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHH
ETAIQEDADLIGLSVLSGAHMTLFRRLLELLRERDAADIVVFGGGIIPEEDIPVLEELGV
HHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHCCC
AKVFTPGAATGEITGWVAEHFAG
CEEECCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TSTTPSGGPAGPSPRIRIVVGKPGLDGHDRGAKIVARALRDAGHEVVYTGLHQTPEQIV
CCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHH
ETAIQEDADLIGLSVLSGAHMTLFRRLLELLRERDAADIVVFGGGIIPEEDIPVLEELGV
HHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHCCC
AKVFTPGAATGEITGWVAEHFAG
CEEECCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9889346; 11481431 [H]