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The map label for this gene is sucC

Identifier: 119717812

GI number: 119717812

Start: 3808449

End: 3809609

Strand: Reverse

Name: sucC

Synonym: Noca_3590

Alternate gene names: 119717812

Gene position: 3809609-3808449 (Counterclockwise)

Preceding gene: 119717813

Following gene: 119717811

Centisome position: 76.41

GC content: 68.56

Gene sequence:

>1161_bases
GTGGATCTGATGGAGTACCAGGCGAAGGAGCTCTTCGCCAAGCACGACGTACCGGTCACTCTCGGCATCGTCGCCCACAC
CCCCGACGAGGCCCAGGCCGCTGCTGAGCAGCTGGGTGTCGTGGTGGTCAAGGCGCAGGTGAAGGCCGGTGGCCGCGGCA
AGGCGGGCGGCGTCAAGCTCGCCAAGACGCCCGAGGAGGCTCGCACGCACGCCGAGGCGATCCTCGGCATGGAGATCAAG
GGCCTCCGCGTGAACCGCGTGCTCATCGCTCCCGCCGCCAGCATCGAGGAGGAGTACTACTTCTCGTTCCTGCTCGACCG
GGCCAACCGTCGCTACCTGTGCATCGCCAGCGTCGAGGGCGGCGTGGAGATCGAGGAGGTCGCCAAGACCAACCCCGACG
CCGTGCGCCAGATCCCGATCGACCCGGGCGCCGGTGTCGACGAGGCCAAGGCTCGGGAGATCGTCGCCGACGCGAAGTTC
CCCGAGGCGCTGACCGAGCAGGCCGTGCAGACCGTGCTCGCGCTCTGGAAGGTCTTCGTCGAGGAGGACGCCACGCTGGT
CGAGGTCAACCCGCTCGCGCGGCTGGCCGGCGACAAGCTCGAGGCGCTCGACGGCAAGGTCTCGCTCGACGAGAACGCCG
AGTTCCGCCACGAGGAGCACGCCTCCTTCGTGATCCGCGAGGAGGAGGACCCGCTCGAGTCCGCCGCCAAGGACAAGGGC
CTGAACTACGTCAAGCTCGACGGCTCGGTCGGGATCATCGGCAACGGCGCCGGTCTGGTCATGTCCACGCTCGACGTCGT
CGCGTATGCCGGTGAGAAGCACGGTGGGGTCAAGCCCGCGAACTTCCTCGACATCGGTGGCGGCGCCAACGCCCAGGTGA
TGGCCGACGGCCTGCACGTGATCCTCGGCGACGAGCAGGTCAAGGCCGTGTTCGTGAACGTGTTCGGCGGGATCACCGCC
TGCGACGAGGTCGCCAACGGCATCGTCGGCGCCCTGGACATCCTCGGTGAGGATGCCACCAAGCCGCTGGTCATCCGGCT
CGACGGCAACAATGCCGACGAAGGCCGCCGGATCCTCACCGAGGCGGCCCACCCTCTCGTGACCATGGTGGACACGATGG
ACGGCGCGGCCGACAAGGCCGCCGAGCTCGCGAACGCCTGA

Upstream 100 bases:

>100_bases
GGGTCCGGACTAGGGTGCCCGAGGACACCCGAGCGACATCCCAGCGGCGCGCGGACGTCAAACGCGTCCGCCCGCTCCTA
CAGAGGAACATGGTGGATCA

Downstream 100 bases:

>100_bases
GACTGGAGACCACGAAGCAATGTCGATCTACCTCAACAAGGACTCCAAGATCATCGTCCAGGGCATGACCGGTGGCATGG
GCTCCAAGCACACCACCCTC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MDLMEYQAKELFAKHDVPVTLGIVAHTPDEAQAAAEQLGVVVVKAQVKAGGRGKAGGVKLAKTPEEARTHAEAILGMEIK
GLRVNRVLIAPAASIEEEYYFSFLLDRANRRYLCIASVEGGVEIEEVAKTNPDAVRQIPIDPGAGVDEAKAREIVADAKF
PEALTEQAVQTVLALWKVFVEEDATLVEVNPLARLAGDKLEALDGKVSLDENAEFRHEEHASFVIREEEDPLESAAKDKG
LNYVKLDGSVGIIGNGAGLVMSTLDVVAYAGEKHGGVKPANFLDIGGGANAQVMADGLHVILGDEQVKAVFVNVFGGITA
CDEVANGIVGALDILGEDATKPLVIRLDGNNADEGRRILTEAAHPLVTMVDTMDGAADKAAELANA

Sequences:

>Translated_386_residues
MDLMEYQAKELFAKHDVPVTLGIVAHTPDEAQAAAEQLGVVVVKAQVKAGGRGKAGGVKLAKTPEEARTHAEAILGMEIK
GLRVNRVLIAPAASIEEEYYFSFLLDRANRRYLCIASVEGGVEIEEVAKTNPDAVRQIPIDPGAGVDEAKAREIVADAKF
PEALTEQAVQTVLALWKVFVEEDATLVEVNPLARLAGDKLEALDGKVSLDENAEFRHEEHASFVIREEEDPLESAAKDKG
LNYVKLDGSVGIIGNGAGLVMSTLDVVAYAGEKHGGVKPANFLDIGGGANAQVMADGLHVILGDEQVKAVFVNVFGGITA
CDEVANGIVGALDILGEDATKPLVIRLDGNNADEGRRILTEAAHPLVTMVDTMDGAADKAAELANA
>Mature_386_residues
MDLMEYQAKELFAKHDVPVTLGIVAHTPDEAQAAAEQLGVVVVKAQVKAGGRGKAGGVKLAKTPEEARTHAEAILGMEIK
GLRVNRVLIAPAASIEEEYYFSFLLDRANRRYLCIASVEGGVEIEEVAKTNPDAVRQIPIDPGAGVDEAKAREIVADAKF
PEALTEQAVQTVLALWKVFVEEDATLVEVNPLARLAGDKLEALDGKVSLDENAEFRHEEHASFVIREEEDPLESAAKDKG
LNYVKLDGSVGIIGNGAGLVMSTLDVVAYAGEKHGGVKPANFLDIGGGANAQVMADGLHVILGDEQVKAVFVNVFGGITA
CDEVANGIVGALDILGEDATKPLVIRLDGNNADEGRRILTEAAHPLVTMVDTMDGAADKAAELANA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=400, Percent_Identity=35.5, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI157779135, Length=390, Percent_Identity=36.1538461538462, Blast_Score=242, Evalue=4e-64,
Organism=Homo sapiens, GI294862256, Length=365, Percent_Identity=36.7123287671233, Blast_Score=226, Evalue=2e-59,
Organism=Escherichia coli, GI1786948, Length=385, Percent_Identity=41.038961038961, Blast_Score=273, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17567829, Length=400, Percent_Identity=36.5, Blast_Score=244, Evalue=7e-65,
Organism=Caenorhabditis elegans, GI17539378, Length=398, Percent_Identity=35.1758793969849, Blast_Score=240, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6321683, Length=403, Percent_Identity=37.2208436724566, Blast_Score=248, Evalue=9e-67,
Organism=Drosophila melanogaster, GI21356231, Length=402, Percent_Identity=34.8258706467662, Blast_Score=231, Evalue=5e-61,
Organism=Drosophila melanogaster, GI161078106, Length=402, Percent_Identity=36.5671641791045, Blast_Score=231, Evalue=8e-61,
Organism=Drosophila melanogaster, GI24645208, Length=402, Percent_Identity=36.5671641791045, Blast_Score=231, Evalue=8e-61,
Organism=Drosophila melanogaster, GI281361397, Length=403, Percent_Identity=36.4764267990074, Blast_Score=226, Evalue=1e-59,
Organism=Drosophila melanogaster, GI281361395, Length=403, Percent_Identity=36.4764267990074, Blast_Score=226, Evalue=1e-59,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_NOCSJ (A1SMQ5)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_924777.1
- ProteinModelPortal:   A1SMQ5
- SMR:   A1SMQ5
- STRING:   A1SMQ5
- GeneID:   4599393
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_3590
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   MADGAEK
- ProtClustDB:   PRK00696
- BioCyc:   NSP35761:NOCA_3590-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 40800; Mature: 40800

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLMEYQAKELFAKHDVPVTLGIVAHTPDEAQAAAEQLGVVVVKAQVKAGGRGKAGGVKL
CCHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHCCEEEEEEEECCCCCCCCCCEEE
AKTPEEARTHAEAILGMEIKGLRVNRVLIAPAASIEEEYYFSFLLDRANRRYLCIASVEG
ECCCHHHHHHHHHHHCEEECCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCC
GVEIEEVAKTNPDAVRQIPIDPGAGVDEAKAREIVADAKFPEALTEQAVQTVLALWKVFV
CCCHHHHHCCCCCHHEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
EEDATLVEVNPLARLAGDKLEALDGKVSLDENAEFRHEEHASFVIREEEDPLESAAKDKG
HCCCEEEEECHHHHHCCCHHHHCCCCEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHCC
LNYVKLDGSVGIIGNGAGLVMSTLDVVAYAGEKHGGVKPANFLDIGGGANAQVMADGLHV
CCEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCEEEECCEEE
ILGDEQVKAVFVNVFGGITACDEVANGIVGALDILGEDATKPLVIRLDGNNADEGRRILT
EECCCCEEEEEEEHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHH
EAAHPLVTMVDTMDGAADKAAELANA
HHCCCCEEEHHHCCCCHHHHHHHCCC
>Mature Secondary Structure
MDLMEYQAKELFAKHDVPVTLGIVAHTPDEAQAAAEQLGVVVVKAQVKAGGRGKAGGVKL
CCHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHCCEEEEEEEECCCCCCCCCCEEE
AKTPEEARTHAEAILGMEIKGLRVNRVLIAPAASIEEEYYFSFLLDRANRRYLCIASVEG
ECCCHHHHHHHHHHHCEEECCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCC
GVEIEEVAKTNPDAVRQIPIDPGAGVDEAKAREIVADAKFPEALTEQAVQTVLALWKVFV
CCCHHHHHCCCCCHHEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
EEDATLVEVNPLARLAGDKLEALDGKVSLDENAEFRHEEHASFVIREEEDPLESAAKDKG
HCCCEEEEECHHHHHCCCHHHHCCCCEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHCC
LNYVKLDGSVGIIGNGAGLVMSTLDVVAYAGEKHGGVKPANFLDIGGGANAQVMADGLHV
CCEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCEEEECCEEE
ILGDEQVKAVFVNVFGGITACDEVANGIVGALDILGEDATKPLVIRLDGNNADEGRRILT
EECCCCEEEEEEEHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHH
EAAHPLVTMVDTMDGAADKAAELANA
HHCCCCEEEHHHCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA