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The map label for this gene is sucD [H]

Identifier: 119717811

GI number: 119717811

Start: 3807536

End: 3808429

Strand: Reverse

Name: sucD [H]

Synonym: Noca_3589

Alternate gene names: 119717811

Gene position: 3808429-3807536 (Counterclockwise)

Preceding gene: 119717812

Following gene: 119717807

Centisome position: 76.38

GC content: 69.35

Gene sequence:

>894_bases
ATGTCGATCTACCTCAACAAGGACTCCAAGATCATCGTCCAGGGCATGACCGGTGGCATGGGCTCCAAGCACACCACCCT
CATGGTCGAGGCGGGGTCCAACATCGTCGGCGGCGTGAACGCGCGCAAGGCCGGCACCTCGATCGAGCTCGGCGGCAAGG
ACCTGCCCGTGTACGGCACGGTCAAGGAGGCGATGGCCGAGACCGGCGCCGACGTGTCGGTCGTGTTCGTCCCGCCCGCC
TTCACCAAGGACGCCTGCATCGAGGCCATCGACGCCGGCATCGCCCTGCTCGTCGTGATCACCGAAGGTGTGCCCGTGCA
GGACACCGCCGAGGTGTTCGCCTACCTGCAGAGCGCCGCGAACACGGGCGGCACCCGGATGATCGGCCCGAACTGCCCCG
GCGTCATCACGCCGGGGGAGGCGTTGGCCGGCATCACGCCCGCCACGATCGCGGGCTCCGGCCCGGTCGGCCTGGTGTCG
AAGTCCGGCACGCTGACCTACCAGATGATGTACGAGCTGCGCGACCACGGCTTCTCGACCGCGATCGGCATCGGTGGTGA
CCCGATCATCGGCACCACCCACATCGACGCCCTCGCGGCGTTCGAGGCCGACCCGGACACCAAGGCGATCGTGATGATCG
GCGAGATCGGCGGCGACGCCGAGGAGCGGGCGGCGGCGTACATCAAGGAGCACGTGACCAAGCCGGTCGTCGGCTACGTC
GCCGGCTTCACCGCGCCCGAGGGCAAGACCATGGGCCACGCCGGCGCCATCGTCTCCGGCTCCTCCGGCACCGCGCAGGC
GAAGAAGGAGGCCCTCGAGGCCGTCGGCGTGAAGGTCGGCAAGACGCCGTCCGAGACCGCCGAGCTCATGCGCGAGGTCC
TCGCCTCGCTCTGA

Upstream 100 bases:

>100_bases
GAGGCGGCCCACCCTCTCGTGACCATGGTGGACACGATGGACGGCGCGGCCGACAAGGCCGCCGAGCTCGCGAACGCCTG
AGACTGGAGACCACGAAGCA

Downstream 100 bases:

>100_bases
TCCACCGCGTAGGACGACGGCCCCGGGCACGCGCTTGCCCGGGGCCGTTCGCCCCGGATCTCGTCCGGCTGGCGCCCGCT
GCTCGACCAACGGCGACCGC

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSIYLNKDSKIIVQGMTGGMGSKHTTLMVEAGSNIVGGVNARKAGTSIELGGKDLPVYGTVKEAMAETGADVSVVFVPPA
FTKDACIEAIDAGIALLVVITEGVPVQDTAEVFAYLQSAANTGGTRMIGPNCPGVITPGEALAGITPATIAGSGPVGLVS
KSGTLTYQMMYELRDHGFSTAIGIGGDPIIGTTHIDALAAFEADPDTKAIVMIGEIGGDAEERAAAYIKEHVTKPVVGYV
AGFTAPEGKTMGHAGAIVSGSSGTAQAKKEALEAVGVKVGKTPSETAELMREVLASL

Sequences:

>Translated_297_residues
MSIYLNKDSKIIVQGMTGGMGSKHTTLMVEAGSNIVGGVNARKAGTSIELGGKDLPVYGTVKEAMAETGADVSVVFVPPA
FTKDACIEAIDAGIALLVVITEGVPVQDTAEVFAYLQSAANTGGTRMIGPNCPGVITPGEALAGITPATIAGSGPVGLVS
KSGTLTYQMMYELRDHGFSTAIGIGGDPIIGTTHIDALAAFEADPDTKAIVMIGEIGGDAEERAAAYIKEHVTKPVVGYV
AGFTAPEGKTMGHAGAIVSGSSGTAQAKKEALEAVGVKVGKTPSETAELMREVLASL
>Mature_296_residues
SIYLNKDSKIIVQGMTGGMGSKHTTLMVEAGSNIVGGVNARKAGTSIELGGKDLPVYGTVKEAMAETGADVSVVFVPPAF
TKDACIEAIDAGIALLVVITEGVPVQDTAEVFAYLQSAANTGGTRMIGPNCPGVITPGEALAGITPATIAGSGPVGLVSK
SGTLTYQMMYELRDHGFSTAIGIGGDPIIGTTHIDALAAFEADPDTKAIVMIGEIGGDAEERAAAYIKEHVTKPVVGYVA
GFTAPEGKTMGHAGAIVSGSSGTAQAKKEALEAVGVKVGKTPSETAELMREVLASL

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=289, Percent_Identity=48.0968858131488, Blast_Score=205, Evalue=5e-53,
Organism=Homo sapiens, GI38569423, Length=259, Percent_Identity=30.8880308880309, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI38569421, Length=259, Percent_Identity=30.8880308880309, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1786949, Length=296, Percent_Identity=56.4189189189189, Blast_Score=307, Evalue=6e-85,
Organism=Caenorhabditis elegans, GI17550194, Length=295, Percent_Identity=48.8135593220339, Blast_Score=241, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI17553126, Length=299, Percent_Identity=46.1538461538462, Blast_Score=226, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17557344, Length=259, Percent_Identity=28.957528957529, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17551266, Length=259, Percent_Identity=28.1853281853282, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324716, Length=306, Percent_Identity=42.8104575163399, Blast_Score=218, Evalue=6e-58,
Organism=Drosophila melanogaster, GI21356559, Length=302, Percent_Identity=44.0397350993377, Blast_Score=239, Evalue=1e-63,
Organism=Drosophila melanogaster, GI28574296, Length=299, Percent_Identity=45.1505016722408, Blast_Score=208, Evalue=4e-54,
Organism=Drosophila melanogaster, GI281363477, Length=259, Percent_Identity=28.957528957529, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281363475, Length=259, Percent_Identity=28.957528957529, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI281363473, Length=259, Percent_Identity=28.957528957529, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30067; Mature: 29936

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIYLNKDSKIIVQGMTGGMGSKHTTLMVEAGSNIVGGVNARKAGTSIELGGKDLPVYGT
CEEEEECCCEEEEEECCCCCCCCCEEEEEECCCCEECCCCCCCCCCEEEECCCCCCEEHH
VKEAMAETGADVSVVFVPPAFTKDACIEAIDAGIALLVVITEGVPVQDTAEVFAYLQSAA
HHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHH
NTGGTRMIGPNCPGVITPGEALAGITPATIAGSGPVGLVSKSGTLTYQMMYELRDHGFST
CCCCCEEECCCCCCEECCCHHHHCCCCCEECCCCCEEEEECCCCEEHHHHHHHHHCCCEE
AIGIGGDPIIGTTHIDALAAFEADPDTKAIVMIGEIGGDAEERAAAYIKEHVTKPVVGYV
EECCCCCCCEECHHHHHHEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHH
AGFTAPEGKTMGHAGAIVSGSSGTAQAKKEALEAVGVKVGKTPSETAELMREVLASL
HCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIYLNKDSKIIVQGMTGGMGSKHTTLMVEAGSNIVGGVNARKAGTSIELGGKDLPVYGT
EEEEECCCEEEEEECCCCCCCCCEEEEEECCCCEECCCCCCCCCCEEEECCCCCCEEHH
VKEAMAETGADVSVVFVPPAFTKDACIEAIDAGIALLVVITEGVPVQDTAEVFAYLQSAA
HHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHH
NTGGTRMIGPNCPGVITPGEALAGITPATIAGSGPVGLVSKSGTLTYQMMYELRDHGFST
CCCCCEEECCCCCCEECCCHHHHCCCCCEECCCCCEEEEECCCCEEHHHHHHHHHCCCEE
AIGIGGDPIIGTTHIDALAAFEADPDTKAIVMIGEIGGDAEERAAAYIKEHVTKPVVGYV
EECCCCCCCEECHHHHHHEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHH
AGFTAPEGKTMGHAGAIVSGSSGTAQAKKEALEAVGVKVGKTPSETAELMREVLASL
HCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]