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The map label for this gene is bioI [H]

Identifier: 119717758

GI number: 119717758

Start: 3746680

End: 3747855

Strand: Reverse

Name: bioI [H]

Synonym: Noca_3536

Alternate gene names: 119717758

Gene position: 3747855-3746680 (Counterclockwise)

Preceding gene: 119717759

Following gene: 119717757

Centisome position: 75.17

GC content: 72.45

Gene sequence:

>1176_bases
ATGCGTTCGGTCCCGACGACCTCGATTGACCTGACCGACCCGGCCGTCGTCGCCGACCCGTACCCGCACTTCGCGCGCGA
GCGTGCGCGGCACCCGGTGGCGTGGCACGAGCCGACCGGCCGGTACCTCACGTTCGCGCACGCGACGGTCGGGCAGGTGC
AGCGCGACCGGCGGCTGGGCCGGCTCTGGAAGGACAAGGAGCCGCTCGACCACCTCGAGCCGTTCAACCTGCTGCACCGC
AACCAGATGATGGAGAACGAGCCGCCCGAGCACACCCGGCTCCGGCGCCCGGTCGCCTCGGCCTTCGCCCGCGGGCACGT
GGAGCGGCTGCGCCCGCGGGTGCGGGAGCTGGCCGCCGAGCTGCTCGCCGGGGTGGACCCGGCGGGCTTCGACGTGGTCG
GGGACTATGCCGAGCCGCTGCCGGTGCTGGTGATCGCGGACCTGCTGGGGGTGCCGCGCACCTACGCGCACTCGCTGCGC
GACTGGTCGCAGGCGATCGTGCGGATGTACGAGGTCTCGCCGCCGCAGGAGACGGTCGACGCGGCCGTCGCCGCCGCGAC
CGACTTCGCCGGCCTGGTGCGCGAGCTGGTGCGGGAGCGGCGTACGGCGCCCGCCGAGGACCTGATCACCGACCTGGTCG
CGACCGAGCTGACCGAGGACGAGGTCGTCGCCGCGGTGGTGCTGCTGCTCAACGCCGGGCACGAGGCCTCGGTCAACGTG
TTCGGCAACGGCCTGACGGCGATGCTGCGTCGCGGCCTGCGTCCTGGGTCCGACGTGCCTCGCACGGTCGAGGAGATGCT
GCGCTTCGACTCCGCGCTCCAGCTGTTCGAGCGGACCGCCATGGAGGACGTGCAGGTCGGCGAGGGCGAGCAGGCCGTGC
TGGTCGAGGAGGGGCAGAAGGTCGTCGCCCTGCTCGGCGCCGCGAACCGCGACCCGGCGGTCTTCGACGACCCCGACGTG
TTCGACGTGGACCGCGATCCCAACAACCACCTGGCGTTCGGGGTCGGTGTGCACTTCTGCCTGGGCGCCCCGCTCGCGAG
GATGGAGCTGGCGGAGTCGGTGTCCGAACTGTTCGAGACGTTCCCCGACCTGGCCCTCACCGGAGCGCCGGAGAGCCGCG
GGACGTTCGTGTTGAGAGGGTTCCGTAGCGTGCCCGTGGGAGGAACACATGCCTGA

Upstream 100 bases:

>100_bases
CCGTGCGGGCGGTGCCGCCAGCTGCTGCACGAGAACGGTGGGCCGGGGCTGCTGCTGTGGACGGTCTCGGGCGTGAAGCG
GATGGACGAGGTGCTGCCGG

Downstream 100 bases:

>100_bases
CCATGACGCCGTCGAGGTGATCGCCGCCAAGCGCGACCGCCACGAGCTGACCGACAGCCAGATCGACTGGGTGGTCGACG
CCTACACCAGGGGTGCGGTC

Product: cytochrome P450

Products: ROH; oxidized flavoprotein; H2O

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRSVPTTSIDLTDPAVVADPYPHFARERARHPVAWHEPTGRYLTFAHATVGQVQRDRRLGRLWKDKEPLDHLEPFNLLHR
NQMMENEPPEHTRLRRPVASAFARGHVERLRPRVRELAAELLAGVDPAGFDVVGDYAEPLPVLVIADLLGVPRTYAHSLR
DWSQAIVRMYEVSPPQETVDAAVAAATDFAGLVRELVRERRTAPAEDLITDLVATELTEDEVVAAVVLLLNAGHEASVNV
FGNGLTAMLRRGLRPGSDVPRTVEEMLRFDSALQLFERTAMEDVQVGEGEQAVLVEEGQKVVALLGAANRDPAVFDDPDV
FDVDRDPNNHLAFGVGVHFCLGAPLARMELAESVSELFETFPDLALTGAPESRGTFVLRGFRSVPVGGTHA

Sequences:

>Translated_391_residues
MRSVPTTSIDLTDPAVVADPYPHFARERARHPVAWHEPTGRYLTFAHATVGQVQRDRRLGRLWKDKEPLDHLEPFNLLHR
NQMMENEPPEHTRLRRPVASAFARGHVERLRPRVRELAAELLAGVDPAGFDVVGDYAEPLPVLVIADLLGVPRTYAHSLR
DWSQAIVRMYEVSPPQETVDAAVAAATDFAGLVRELVRERRTAPAEDLITDLVATELTEDEVVAAVVLLLNAGHEASVNV
FGNGLTAMLRRGLRPGSDVPRTVEEMLRFDSALQLFERTAMEDVQVGEGEQAVLVEEGQKVVALLGAANRDPAVFDDPDV
FDVDRDPNNHLAFGVGVHFCLGAPLARMELAESVSELFETFPDLALTGAPESRGTFVLRGFRSVPVGGTHA
>Mature_391_residues
MRSVPTTSIDLTDPAVVADPYPHFARERARHPVAWHEPTGRYLTFAHATVGQVQRDRRLGRLWKDKEPLDHLEPFNLLHR
NQMMENEPPEHTRLRRPVASAFARGHVERLRPRVRELAAELLAGVDPAGFDVVGDYAEPLPVLVIADLLGVPRTYAHSLR
DWSQAIVRMYEVSPPQETVDAAVAAATDFAGLVRELVRERRTAPAEDLITDLVATELTEDEVVAAVVLLLNAGHEASVNV
FGNGLTAMLRRGLRPGSDVPRTVEEMLRFDSALQLFERTAMEDVQVGEGEQAVLVEEGQKVVALLGAANRDPAVFDDPDV
FDVDRDPNNHLAFGVGVHFCLGAPLARMELAESVSELFETFPDLALTGAPESRGTFVLRGFRSVPVGGTHA

Specific function: Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynthesis. It has high affinity for long-chain fatty acids with the greatest affinity for myristic acid [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: 1.14.14.1

Molecular weight: Translated: 43049; Mature: 43049

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSVPTTSIDLTDPAVVADPYPHFARERARHPVAWHEPTGRYLTFAHATVGQVQRDRRLG
CCCCCCCEECCCCCCEECCCCHHHHHHHHCCCCCEECCCCCEEEEHHHHHHHHHHHHHHH
RLWKDKEPLDHLEPFNLLHRNQMMENEPPEHTRLRRPVASAFARGHVERLRPRVRELAAE
HHHCCCCCHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAGVDPAGFDVVGDYAEPLPVLVIADLLGVPRTYAHSLRDWSQAIVRMYEVSPPQETVD
HHHCCCCCCCCHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AAVAAATDFAGLVRELVRERRTAPAEDLITDLVATELTEDEVVAAVVLLLNAGHEASVNV
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEE
FGNGLTAMLRRGLRPGSDVPRTVEEMLRFDSALQLFERTAMEDVQVGEGEQAVLVEEGQK
CCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
VVALLGAANRDPAVFDDPDVFDVDRDPNNHLAFGVGVHFCLGAPLARMELAESVSELFET
EEHHHHCCCCCCCCCCCCCCEECCCCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHHHH
FPDLALTGAPESRGTFVLRGFRSVPVGGTHA
CCCCEECCCCCCCCCEEEECCCCCCCCCCCC
>Mature Secondary Structure
MRSVPTTSIDLTDPAVVADPYPHFARERARHPVAWHEPTGRYLTFAHATVGQVQRDRRLG
CCCCCCCEECCCCCCEECCCCHHHHHHHHCCCCCEECCCCCEEEEHHHHHHHHHHHHHHH
RLWKDKEPLDHLEPFNLLHRNQMMENEPPEHTRLRRPVASAFARGHVERLRPRVRELAAE
HHHCCCCCHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAGVDPAGFDVVGDYAEPLPVLVIADLLGVPRTYAHSLRDWSQAIVRMYEVSPPQETVD
HHHCCCCCCCCHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AAVAAATDFAGLVRELVRERRTAPAEDLITDLVATELTEDEVVAAVVLLLNAGHEASVNV
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEE
FGNGLTAMLRRGLRPGSDVPRTVEEMLRFDSALQLFERTAMEDVQVGEGEQAVLVEEGQK
CCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
VVALLGAANRDPAVFDDPDVFDVDRDPNNHLAFGVGVHFCLGAPLARMELAESVSELFET
EEHHHHCCCCCCCCCCCCCCEECCCCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHHHH
FPDLALTGAPESRGTFVLRGFRSVPVGGTHA
CCCCEECCCCCCCCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RH; reduced flavoprotein; O2

Specific reaction: RH + reduced flavoprotein + O2 = ROH + oxidized flavoprotein + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8763940; 9387221; 9384377 [H]