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The map label for this gene is cdd [H]

Identifier: 119717759

GI number: 119717759

Start: 3747827

End: 3748228

Strand: Reverse

Name: cdd [H]

Synonym: Noca_3537

Alternate gene names: 119717759

Gene position: 3748228-3747827 (Counterclockwise)

Preceding gene: 119717760

Following gene: 119717758

Centisome position: 75.18

GC content: 69.9

Gene sequence:

>402_bases
GTGAGCGCCCAGGACACCGAGTTCGACTGGGAGTCGCTCAAGGCGGCGGCCGAGGAGGCGATGAGGCACGCGTACGTGCC
GTACTCGCGCTTCTCGGTCGGCGCCGCGGCGCTCGTCGACGACGGTCGGACGGTGGTCGGCTGCAACGTCGAGAACGCGT
CGTACGGCGTCGGCCTGTGCGCCGAGTGCGGACTGGTCAGCCAGCTGCACATCAGCGGTGGCGGGCGGCTGACGCACTTC
GTGTGCGTCAACGGCGAGCGCGAGATCATCATGCCGTGCGGGCGGTGCCGCCAGCTGCTGCACGAGAACGGTGGGCCGGG
GCTGCTGCTGTGGACGGTCTCGGGCGTGAAGCGGATGGACGAGGTGCTGCCGGATGCGTTCGGTCCCGACGACCTCGATT
GA

Upstream 100 bases:

>100_bases
CGCCGTACGTCATCACGATGCTGGTGCTCGCCTTCGCCTCACAACGATTGCGGATGCCGACAGCCGACGGGCAGATCTAC
CGCAAGGGCAGCGCAGGGTA

Downstream 100 bases:

>100_bases
CCTGACCGACCCGGCCGTCGTCGCCGACCCGTACCCGCACTTCGCGCGCGAGCGTGCGCGGCACCCGGTGGCGTGGCACG
AGCCGACCGGCCGGTACCTC

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MSAQDTEFDWESLKAAAEEAMRHAYVPYSRFSVGAAALVDDGRTVVGCNVENASYGVGLCAECGLVSQLHISGGGRLTHF
VCVNGEREIIMPCGRCRQLLHENGGPGLLLWTVSGVKRMDEVLPDAFGPDDLD

Sequences:

>Translated_133_residues
MSAQDTEFDWESLKAAAEEAMRHAYVPYSRFSVGAAALVDDGRTVVGCNVENASYGVGLCAECGLVSQLHISGGGRLTHF
VCVNGEREIIMPCGRCRQLLHENGGPGLLLWTVSGVKRMDEVLPDAFGPDDLD
>Mature_132_residues
SAQDTEFDWESLKAAAEEAMRHAYVPYSRFSVGAAALVDDGRTVVGCNVENASYGVGLCAECGLVSQLHISGGGRLTHFV
CVNGEREIIMPCGRCRQLLHENGGPGLLLWTVSGVKRMDEVLPDAFGPDDLD

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=129, Percent_Identity=37.984496124031, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17540514, Length=121, Percent_Identity=41.3223140495868, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17551074, Length=138, Percent_Identity=39.8550724637681, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323274, Length=131, Percent_Identity=38.1679389312977, Blast_Score=80, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24582741, Length=101, Percent_Identity=38.6138613861386, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14286; Mature: 14155

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQDTEFDWESLKAAAEEAMRHAYVPYSRFSVGAAALVDDGRTVVGCNVENASYGVGLC
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHH
AECGLVSQLHISGGGRLTHFVCVNGEREIIMPCGRCRQLLHENGGPGLLLWTVSGVKRMD
HCCCCEEEEEECCCCEEEEEEEECCCCEEEECCHHHHHHHHCCCCCEEEEEECCCHHHHH
EVLPDAFGPDDLD
HHCCCCCCCCCCC
>Mature Secondary Structure 
SAQDTEFDWESLKAAAEEAMRHAYVPYSRFSVGAAALVDDGRTVVGCNVENASYGVGLC
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHH
AECGLVSQLHISGGGRLTHFVCVNGEREIIMPCGRCRQLLHENGGPGLLLWTVSGVKRMD
HCCCCEEEEEECCCCEEEEEEEECCCCEEEECCHHHHHHHHCCCCCEEEEEECCCHHHHH
EVLPDAFGPDDLD
HHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]