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The map label for this gene is ddl [H]

Identifier: 119717515

GI number: 119717515

Start: 3497459

End: 3498580

Strand: Reverse

Name: ddl [H]

Synonym: Noca_3291

Alternate gene names: 119717515

Gene position: 3498580-3497459 (Counterclockwise)

Preceding gene: 119717517

Following gene: 119717512

Centisome position: 70.17

GC content: 72.99

Gene sequence:

>1122_bases
ATGAACGAGTCCAGCCGCCGACCCCGGGTCGCCGTCGTCTTCGGCGGCAAGTCCAGCGAGCACGCGATCTCGTGCGTCAC
GGCCGGCAGCGTGCTGGCCGCGATCGACCGGGCGGCGTACGACGTCGTCCCGATCGGCATCGCCACCGACGGCCGCTGGG
TGCTGGAGTCGGGCGACCCCGAGCGGCTGCGCATCGAGGGCCCCGACCGGCTGCCCCACGTCGACGGCGAACGCGCGGCG
ATCGCGCTGGCCCCGGACACCGCATCGACGAGCCTGGTCGTCACCGAGCCGGCACAGCCCCCGCGCGCGCTGGGGGAGGT
GGACGTGGTGTTCCCGCTGCTGCACGGTCCGTGGGGCGAGGACGGCACCATCCAGGGCCTGCTCGAGATGGCCGGTGTCC
GGTACGTCGGCGCCGGGGTGCTCGCGTCCGCGGTGAGCATGGACAAGGCGTACATGAAGGTGGTGCTGGCCGCCGCCGGC
CTGCCGGTGCTGCCGTCGGTGACCGTGACCACCCGTGAGTGGGCGCGTGACGCCGCCGGCTGCCGCGCTCGCGCCGACGA
GATCGGCTACCCGCTGTTCGTCAAGCCCGCGCGGGGCGGCTCGAGCCTCGGCATCTCCAAGGTCCACGACGCGACCGAGC
TCGACGGCGCGATCGAGCTGGCCTTCGAGCACGACCCGAAGGTGCTGGTCGAGACGGCGGCGATCGACGCCCGGGAGGTC
GAGTGCGGCGTGCTGCAGGCCGTCGACGGGACCCCGGAGACCAGCGTGCCCGCCGAGATCCGGATCTCCGGTGCGCACGA
GTTCTACGACTTCGCCGCGAAGTACCTGCCGGAGGAGCACACCGAGCTGGACGTGCCGGCCGACCTGCCCGAGGCGCTGG
TCCGCCAGGTCCGGGAGCTGTCCGTGCGCGCCTTCGAGGCGGTCGGCTGCGAGGGCCTGGCCCGGGTCGACTTCTTCGTG
CTCCCCGGTGAGCGGCTCGTGGTCAACGAGATCAACACGATGCCGGGCTTCACGCCGACCTCGATGTTCCCGCGGATGTG
GGCGGCCTCGGGCCTGGACTACCCGGCGCTCGTGGACCGGTTGATCCAGCTCGCGTTGCGGCGCGACACCGGGCTGCGCT
GA

Upstream 100 bases:

>100_bases
TCGCGTTCCGGCCGGCCGGAGGTGACGGCGATCGTGGCCGGCTTCAGGTCCCGCGAGGCGCTGCTCATGGGACCACGCTA
GACGGATAGGGTCGGGCCCG

Downstream 100 bases:

>100_bases
CCCTGCGTCGGCCGCGCCCCACCCACGATCACCGGCACTCGTCGCGCAGGGTGAGGTGCTCGCGCACCGGCCGCGCCAAC
GAGGCGAGTGCGTCGGCCGA

Product: D-alanine--D-alanine ligase

Products: NA

Alternate protein names: D-Ala-D-Ala ligase; D-alanylalanine synthetase [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MNESSRRPRVAVVFGGKSSEHAISCVTAGSVLAAIDRAAYDVVPIGIATDGRWVLESGDPERLRIEGPDRLPHVDGERAA
IALAPDTASTSLVVTEPAQPPRALGEVDVVFPLLHGPWGEDGTIQGLLEMAGVRYVGAGVLASAVSMDKAYMKVVLAAAG
LPVLPSVTVTTREWARDAAGCRARADEIGYPLFVKPARGGSSLGISKVHDATELDGAIELAFEHDPKVLVETAAIDAREV
ECGVLQAVDGTPETSVPAEIRISGAHEFYDFAAKYLPEEHTELDVPADLPEALVRQVRELSVRAFEAVGCEGLARVDFFV
LPGERLVVNEINTMPGFTPTSMFPRMWAASGLDYPALVDRLIQLALRRDTGLR

Sequences:

>Translated_373_residues
MNESSRRPRVAVVFGGKSSEHAISCVTAGSVLAAIDRAAYDVVPIGIATDGRWVLESGDPERLRIEGPDRLPHVDGERAA
IALAPDTASTSLVVTEPAQPPRALGEVDVVFPLLHGPWGEDGTIQGLLEMAGVRYVGAGVLASAVSMDKAYMKVVLAAAG
LPVLPSVTVTTREWARDAAGCRARADEIGYPLFVKPARGGSSLGISKVHDATELDGAIELAFEHDPKVLVETAAIDAREV
ECGVLQAVDGTPETSVPAEIRISGAHEFYDFAAKYLPEEHTELDVPADLPEALVRQVRELSVRAFEAVGCEGLARVDFFV
LPGERLVVNEINTMPGFTPTSMFPRMWAASGLDYPALVDRLIQLALRRDTGLR
>Mature_373_residues
MNESSRRPRVAVVFGGKSSEHAISCVTAGSVLAAIDRAAYDVVPIGIATDGRWVLESGDPERLRIEGPDRLPHVDGERAA
IALAPDTASTSLVVTEPAQPPRALGEVDVVFPLLHGPWGEDGTIQGLLEMAGVRYVGAGVLASAVSMDKAYMKVVLAAAG
LPVLPSVTVTTREWARDAAGCRARADEIGYPLFVKPARGGSSLGISKVHDATELDGAIELAFEHDPKVLVETAAIDAREV
ECGVLQAVDGTPETSVPAEIRISGAHEFYDFAAKYLPEEHTELDVPADLPEALVRQVRELSVRAFEAVGCEGLARVDFFV
LPGERLVVNEINTMPGFTPTSMFPRMWAASGLDYPALVDRLIQLALRRDTGLR

Specific function: Cell wall formation [H]

COG id: COG1181

COG function: function code M; D-alanine-D-alanine ligase and related ATP-grasp enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Escherichia coli, GI1786579, Length=364, Percent_Identity=41.2087912087912, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI1786280, Length=358, Percent_Identity=32.6815642458101, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR000291
- InterPro:   IPR005905
- InterPro:   IPR011095
- InterPro:   IPR011127
- InterPro:   IPR013817
- InterPro:   IPR016185 [H]

Pfam domain/function: PF07478 Dala_Dala_lig_C; PF01820 Dala_Dala_lig_N [H]

EC number: =6.3.2.4 [H]

Molecular weight: Translated: 39822; Mature: 39822

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50975 ATP_GRASP ; PS00843 DALA_DALA_LIGASE_1 ; PS00844 DALA_DALA_LIGASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESSRRPRVAVVFGGKSSEHAISCVTAGSVLAAIDRAAYDVVPIGIATDGRWVLESGDP
CCCCCCCCEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHEEEEEEEECCCEEEEECCCC
ERLRIEGPDRLPHVDGERAAIALAPDTASTSLVVTEPAQPPRALGEVDVVFPLLHGPWGE
CEEEECCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCHHHCCCEEEEEECCCCCCC
DGTIQGLLEMAGVRYVGAGVLASAVSMDKAYMKVVLAAAGLPVLPSVTVTTREWARDAAG
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHC
CRARADEIGYPLFVKPARGGSSLGISKVHDATELDGAIELAFEHDPKVLVETAAIDAREV
CCCCHHHCCCCEEEEECCCCCCCCCHHHCCCHHCCCEEEEEEECCCCEEEEEECCCCHHC
ECGVLQAVDGTPETSVPAEIRISGAHEFYDFAAKYLPEEHTELDVPADLPEALVRQVREL
CCCEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
SVRAFEAVGCEGLARVDFFVLPGERLVVNEINTMPGFTPTSMFPRMWAASGLDYPALVDR
HHHHHHHHCCCCEEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHH
LIQLALRRDTGLR
HHHHHHHHCCCCC
>Mature Secondary Structure
MNESSRRPRVAVVFGGKSSEHAISCVTAGSVLAAIDRAAYDVVPIGIATDGRWVLESGDP
CCCCCCCCEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHEEEEEEEECCCEEEEECCCC
ERLRIEGPDRLPHVDGERAAIALAPDTASTSLVVTEPAQPPRALGEVDVVFPLLHGPWGE
CEEEECCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCHHHCCCEEEEEECCCCCCC
DGTIQGLLEMAGVRYVGAGVLASAVSMDKAYMKVVLAAAGLPVLPSVTVTTREWARDAAG
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHC
CRARADEIGYPLFVKPARGGSSLGISKVHDATELDGAIELAFEHDPKVLVETAAIDAREV
CCCCHHHCCCCEEEEECCCCCCCCCHHHCCCHHCCCEEEEEEECCCCEEEEEECCCCHHC
ECGVLQAVDGTPETSVPAEIRISGAHEFYDFAAKYLPEEHTELDVPADLPEALVRQVREL
CCCEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
SVRAFEAVGCEGLARVDFFVLPGERLVVNEINTMPGFTPTSMFPRMWAASGLDYPALVDR
HHHHHHHHCCCCEEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHH
LIQLALRRDTGLR
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA