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The map label for this gene is thiL [H]

Identifier: 119717512

GI number: 119717512

Start: 3495603

End: 3496553

Strand: Reverse

Name: thiL [H]

Synonym: Noca_3288

Alternate gene names: 119717512

Gene position: 3496553-3495603 (Counterclockwise)

Preceding gene: 119717515

Following gene: 119717510

Centisome position: 70.13

GC content: 76.55

Gene sequence:

>951_bases
ATGTCGTTCCCCCCTGACGCGACGCTGGCCGATGCCGGCGAGTTCGGCCTGATCCGCGCACTCGTGGACCTGTTCCCCCA
GGGGGAGCAGGTCCTGGTGGGCCCCGGCGACGACGCCGCGGTGCTCCGGGTGCGGACCGGCCACGTGGTCGTCTCGACCG
ACCTGATGGTCGAGGGCCGCCACTTCCGGCGCGAGTGGGCCGCGGCCGCCGACGTCGGGCACCGCGCGGCCGCGCAGAAC
CTCTCCGACGTCAACGCGATGGGCGGCCGAGCCACGTCGCTGACGATCGGACTGGCCGCGCCGGCGGACCTGCCCGCGCA
GTGGGCCCTGGACTTCGCGCGTGGGTTCGCCGCCGAGTGCGACCTGGTGGGCGCCAGCGTCGTGGGCGGTGACGTGACCC
GGGCCGACGAGATCGTGGTCGCCGTCACCGTGCTCGGCGCCTGCACCGAGTCGCCGGTGCTGCGCTCCGGCGCGCGGCCG
GGCGACGTCCTCGCGATCTGCGGTCGCCAGGGCTGGGCCGCCGGCGGTCTCGCGGTGCTCGGGCGGGGCTTCCGCTCACC
CCGGGTCCTCGTGGAGGCCTACCGTCGCCCGGAGCCGCCGTACGACGCCGGCCGGACCGCCGCCGAGGCCGGTGCCACGG
CGATGATCGACGTCTCCGACGGGCTGCTCGCCGACGCGGGCCACATCGCGGCCGACTCCGGGGTGGCCATCGACGTGCAC
GCGGCCGCGTTCGACGTCCCCGAGCCGCTGCACGCGGTCGGCGCGGCGATCGGGGCCGACCCGATCCAGTTCATCCTCGG
CGGCGGCGACGACCACGCGCTGCTCGCCACCTTCCCGGACGTCGCGTCGGTCCCCGACGGCTGGTCGGTCATCGGCGCCG
CCGCCGCGGGCGAGGGGGTCACCGTCGACGGCGCCGCGTACGACGGCCCCACCGGCTGGACGCACTTCTGA

Upstream 100 bases:

>100_bases
GCTCTCCCTGGGATCTGGAACGGGTGATCTGGTTCTGCTGGCGTTGTGCCACGCCAACCTACCGCGCGGTACCCCTGCCC
GCATCTGGTGGGATGGGTCC

Downstream 100 bases:

>100_bases
GGCAAACGAAAAGGCCGCCACCCCGAGGGGTGGCGGCCTGCTCGCCAGCGATGGCGGCTTCGCCGCGACCGCTAGCGCGT
GACCTTCCCGGCCTTCAGGC

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSFPPDATLADAGEFGLIRALVDLFPQGEQVLVGPGDDAAVLRVRTGHVVVSTDLMVEGRHFRREWAAAADVGHRAAAQN
LSDVNAMGGRATSLTIGLAAPADLPAQWALDFARGFAAECDLVGASVVGGDVTRADEIVVAVTVLGACTESPVLRSGARP
GDVLAICGRQGWAAGGLAVLGRGFRSPRVLVEAYRRPEPPYDAGRTAAEAGATAMIDVSDGLLADAGHIAADSGVAIDVH
AAAFDVPEPLHAVGAAIGADPIQFILGGGDDHALLATFPDVASVPDGWSVIGAAAAGEGVTVDGAAYDGPTGWTHF

Sequences:

>Translated_316_residues
MSFPPDATLADAGEFGLIRALVDLFPQGEQVLVGPGDDAAVLRVRTGHVVVSTDLMVEGRHFRREWAAAADVGHRAAAQN
LSDVNAMGGRATSLTIGLAAPADLPAQWALDFARGFAAECDLVGASVVGGDVTRADEIVVAVTVLGACTESPVLRSGARP
GDVLAICGRQGWAAGGLAVLGRGFRSPRVLVEAYRRPEPPYDAGRTAAEAGATAMIDVSDGLLADAGHIAADSGVAIDVH
AAAFDVPEPLHAVGAAIGADPIQFILGGGDDHALLATFPDVASVPDGWSVIGAAAAGEGVTVDGAAYDGPTGWTHF
>Mature_315_residues
SFPPDATLADAGEFGLIRALVDLFPQGEQVLVGPGDDAAVLRVRTGHVVVSTDLMVEGRHFRREWAAAADVGHRAAAQNL
SDVNAMGGRATSLTIGLAAPADLPAQWALDFARGFAAECDLVGASVVGGDVTRADEIVVAVTVLGACTESPVLRSGARPG
DVLAICGRQGWAAGGLAVLGRGFRSPRVLVEAYRRPEPPYDAGRTAAEAGATAMIDVSDGLLADAGHIAADSGVAIDVHA
AAFDVPEPLHAVGAAIGADPIQFILGGGDDHALLATFPDVASVPDGWSVIGAAAAGEGVTVDGAAYDGPTGWTHF

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=328, Percent_Identity=30.7926829268293, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 31982; Mature: 31851

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPPDATLADAGEFGLIRALVDLFPQGEQVLVGPGDDAAVLRVRTGHVVVSTDLMVEGR
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCEEEEEEEEEECCH
HFRREWAAAADVGHRAAAQNLSDVNAMGGRATSLTIGLAAPADLPAQWALDFARGFAAEC
HHHHHHHHHHHHHHHHHHHCHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCC
DLVGASVVGGDVTRADEIVVAVTVLGACTESPVLRSGARPGDVLAICGRQGWAAGGLAVL
CEECCEEECCCCCCCCCEEEEEEEHHCCCCCCHHHCCCCCCCEEEEECCCCCCCCCHHHH
GRGFRSPRVLVEAYRRPEPPYDAGRTAAEAGATAMIDVSDGLLADAGHIAADSGVAIDVH
CCCCCCHHHHHHHHHCCCCCCCCCCHHHHCCCEEEEECCCCCEECCCCEECCCCCEEEEE
AAAFDVPEPLHAVGAAIGADPIQFILGGGDDHALLATFPDVASVPDGWSVIGAAAAGEGV
HHCCCCCCHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCHHCCCCCHHEEEHHCCCCCE
TVDGAAYDGPTGWTHF
EECCCCCCCCCCCCCC
>Mature Secondary Structure 
SFPPDATLADAGEFGLIRALVDLFPQGEQVLVGPGDDAAVLRVRTGHVVVSTDLMVEGR
CCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCEEEEEEEEEECCH
HFRREWAAAADVGHRAAAQNLSDVNAMGGRATSLTIGLAAPADLPAQWALDFARGFAAEC
HHHHHHHHHHHHHHHHHHHCHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCC
DLVGASVVGGDVTRADEIVVAVTVLGACTESPVLRSGARPGDVLAICGRQGWAAGGLAVL
CEECCEEECCCCCCCCCEEEEEEEHHCCCCCCHHHCCCCCCCEEEEECCCCCCCCCHHHH
GRGFRSPRVLVEAYRRPEPPYDAGRTAAEAGATAMIDVSDGLLADAGHIAADSGVAIDVH
CCCCCCHHHHHHHHHCCCCCCCCCCHHHHCCCEEEEECCCCCEECCCCEECCCCCEEEEE
AAAFDVPEPLHAVGAAIGADPIQFILGGGDDHALLATFPDVASVPDGWSVIGAAAAGEGV
HHCCCCCCHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCHHCCCCCHHEEEHHCCCCCE
TVDGAAYDGPTGWTHF
EECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377; 8419296 [H]