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The map label for this gene is 119716702

Identifier: 119716702

GI number: 119716702

Start: 2637534

End: 2638127

Strand: Direct

Name: 119716702

Synonym: Noca_2476

Alternate gene names: NA

Gene position: 2637534-2638127 (Clockwise)

Preceding gene: 119716701

Following gene: 119716703

Centisome position: 52.9

GC content: 75.93

Gene sequence:

>594_bases
GTGACCGGCTCGGCTGACCTTCCCGCCCAGCTCGCCGGCCCCGTCCTCGACGTGGCGCCGCGGCTGCTGAACGCGGTGCT
CCGGCACGGCGACGTCGCGGTGCGGCTGACCGAGGTCGAGGCGTACGACGGCGCGAACGACCCCGGCTCGCACGCCTTTC
GTGGCCCGACGCGGCGCAACGCCGTGATGTTCGGCCCCGCCGGACACCTGTACTGCTACTTCACCTACGGCATGCACGTG
TGCTGCAACGTCGTCTGCGGAACCGAGGGGACGGCCAGCGCCGTGCTGCTGCGCGCGGGCGAGGTCGTCGAGGGCCTGGA
GCAGGCCCGGGAGCGTCGTCGCAACGCCCGCGACCGCGACCTGGCTCGCGGACCCGCGCGGCTCTGCTCGGCCCTGGGGA
TCGAGCTCGGCCACGACGGCACCGACCTCGTCACCGGCCCGATCACGCTCACGCTGGGGGAGCCTCCGGACCGGGTCTCC
ACCGGCCCGCGGGTCGGCCTGCGCGGCGCACCCGACCGGCCGTGGCGGTTCTGGGCGACCGGCGATCCGACCGTCTCGGC
CTACCGTCCGGCGGCCCCGCCCCGCCGCCGGTAG

Upstream 100 bases:

>100_bases
GTCGCCGGCTCCGTCTCGGCGCGGGACGGACGCGGCGGCACCGCGCCGATCCGGGTCCGCGAGCAGCTCGCCGAGCTCAC
CGGCCTCGTCGACGGACACC

Downstream 100 bases:

>100_bases
CGCGCCGGCCCGACCCGGTTTGGCTCCTGGCCGAGACCCCTGGTAGATTTCTCCTTCGCCGCGACACGCGGCTCCCACTC
GGGCCGAGAGGCCGACATCG

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MTGSADLPAQLAGPVLDVAPRLLNAVLRHGDVAVRLTEVEAYDGANDPGSHAFRGPTRRNAVMFGPAGHLYCYFTYGMHV
CCNVVCGTEGTASAVLLRAGEVVEGLEQARERRRNARDRDLARGPARLCSALGIELGHDGTDLVTGPITLTLGEPPDRVS
TGPRVGLRGAPDRPWRFWATGDPTVSAYRPAAPPRRR

Sequences:

>Translated_197_residues
MTGSADLPAQLAGPVLDVAPRLLNAVLRHGDVAVRLTEVEAYDGANDPGSHAFRGPTRRNAVMFGPAGHLYCYFTYGMHV
CCNVVCGTEGTASAVLLRAGEVVEGLEQARERRRNARDRDLARGPARLCSALGIELGHDGTDLVTGPITLTLGEPPDRVS
TGPRVGLRGAPDRPWRFWATGDPTVSAYRPAAPPRRR
>Mature_196_residues
TGSADLPAQLAGPVLDVAPRLLNAVLRHGDVAVRLTEVEAYDGANDPGSHAFRGPTRRNAVMFGPAGHLYCYFTYGMHVC
CNVVCGTEGTASAVLLRAGEVVEGLEQARERRRNARDRDLARGPARLCSALGIELGHDGTDLVTGPITLTLGEPPDRVST
GPRVGLRGAPDRPWRFWATGDPTVSAYRPAAPPRRR

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family [H]

Homologues:

Organism=Homo sapiens, GI62632769, Length=171, Percent_Identity=38.5964912280702, Blast_Score=84, Evalue=7e-17,
Organism=Homo sapiens, GI62632771, Length=171, Percent_Identity=38.5964912280702, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI62632765, Length=171, Percent_Identity=38.5964912280702, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011034
- InterPro:   IPR003180 [H]

Pfam domain/function: PF02245 Pur_DNA_glyco [H]

EC number: 3.2.2.-

Molecular weight: Translated: 21076; Mature: 20945

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGSADLPAQLAGPVLDVAPRLLNAVLRHGDVAVRLTEVEAYDGANDPGSHAFRGPTRRN
CCCCCCCCHHHHCHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCC
AVMFGPAGHLYCYFTYGMHVCCNVVCGTEGTASAVLLRAGEVVEGLEQARERRRNARDRD
EEEECCCCCEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LARGPARLCSALGIELGHDGTDLVTGPITLTLGEPPDRVSTGPRVGLRGAPDRPWRFWAT
HHCCHHHHHHHHCCCCCCCCCCEEECCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEC
GDPTVSAYRPAAPPRRR
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TGSADLPAQLAGPVLDVAPRLLNAVLRHGDVAVRLTEVEAYDGANDPGSHAFRGPTRRN
CCCCCCCHHHHCHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCC
AVMFGPAGHLYCYFTYGMHVCCNVVCGTEGTASAVLLRAGEVVEGLEQARERRRNARDRD
EEEECCCCCEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LARGPARLCSALGIELGHDGTDLVTGPITLTLGEPPDRVSTGPRVGLRGAPDRPWRFWAT
HHCCHHHHHHHHCCCCCCCCCCEEECCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEC
GDPTVSAYRPAAPPRRR
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]