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The map label for this gene is ribA [H]

Identifier: 119715919

GI number: 119715919

Start: 1790692

End: 1791294

Strand: Direct

Name: ribA [H]

Synonym: Noca_1684

Alternate gene names: 119715919

Gene position: 1790692-1791294 (Clockwise)

Preceding gene: 119715918

Following gene: 119715923

Centisome position: 35.92

GC content: 73.8

Gene sequence:

>603_bases
GTGACGGCCGCGGTCCGCACCGAGCTGATGGTCCCGCTGCGCCTCGCGGACGGCTGGTCCACGCTCGCGCGGCTCTACAC
CTTCGACGGCCTCACCGACCCCGGGGAGCACCTCGCCCTGCGGCTCGGCTCGCCCGGCGACGTACCCCTCGTGCGGGTGC
ACAGCGAGTGCCTCACCGGCGACGTCTTCGGCAGCCAGCGCTGCGACTGCGGCCCCCAGCTCCACGAGGCGTTCCGGCGC
GTCGACGCCGTCGGCGGGTACGTGCTCTACCTGCGCCAGGAGGGGCGCGGCATCGGGCTCTACCCCAAGCTGGACGCCTA
CGCCCTCCAGGACGCCGGCCTCGACACCTACGAGGCGAACGTCGCGCTCGGGTACGGCGAGGACGAGCGCGACTACTCGG
TCGCGGCCCAGATGCTCACCGCGCTCGGTGTCTCCCGGGTCGCGCTGCTCAGCAACAACCCGGACAAGGCCGAGCAGCTG
GCCCTCGACGGGATCACGGTCGCCGCCCGCGTCCCGACCGCCGTCCACCGCTCCGAGGCGAATGCGCGCTACCTCGCCGC
GAAGGCCCAGCACGCCGACCACACCCTCGACCTGGGCGCCTGA

Upstream 100 bases:

>100_bases
CGTTCCGGTCAGACCGGCCGGCCCGCCTGGTCGACGTGCGCCGGATCGGCGAGGTCGTGCTGCTGCGCTACGCGCTCTCC
TCCAGGTTCGAGGACGCGTC

Downstream 100 bases:

>100_bases
GCGGGCCGCAGCACCACACTCACAGTCACGCGGACCGAGCAAGCGGTGACACCGTCCGCATGACCTCCCGGAGGCCCCTG
TCCCGACCGGTGGGGCTCAG

Product: GTP cyclohydrolase II

Products: NA

Alternate protein names: GTP cyclohydrolase II [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MTAAVRTELMVPLRLADGWSTLARLYTFDGLTDPGEHLALRLGSPGDVPLVRVHSECLTGDVFGSQRCDCGPQLHEAFRR
VDAVGGYVLYLRQEGRGIGLYPKLDAYALQDAGLDTYEANVALGYGEDERDYSVAAQMLTALGVSRVALLSNNPDKAEQL
ALDGITVAARVPTAVHRSEANARYLAAKAQHADHTLDLGA

Sequences:

>Translated_200_residues
MTAAVRTELMVPLRLADGWSTLARLYTFDGLTDPGEHLALRLGSPGDVPLVRVHSECLTGDVFGSQRCDCGPQLHEAFRR
VDAVGGYVLYLRQEGRGIGLYPKLDAYALQDAGLDTYEANVALGYGEDERDYSVAAQMLTALGVSRVALLSNNPDKAEQL
ALDGITVAARVPTAVHRSEANARYLAAKAQHADHTLDLGA
>Mature_199_residues
TAAVRTELMVPLRLADGWSTLARLYTFDGLTDPGEHLALRLGSPGDVPLVRVHSECLTGDVFGSQRCDCGPQLHEAFRRV
DAVGGYVLYLRQEGRGIGLYPKLDAYALQDAGLDTYEANVALGYGEDERDYSVAAQMLTALGVSRVALLSNNPDKAEQLA
LDGITVAARVPTAVHRSEANARYLAAKAQHADHTLDLGA

Specific function: Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate [H]

COG id: COG0807

COG function: function code H; GTP cyclohydrolase II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1787533, Length=173, Percent_Identity=50.2890173410405, Blast_Score=154, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6319438, Length=123, Percent_Identity=47.1544715447154, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000926 [H]

Pfam domain/function: PF00925 GTP_cyclohydro2 [H]

EC number: =3.5.4.25 [H]

Molecular weight: Translated: 21494; Mature: 21363

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAVRTELMVPLRLADGWSTLARLYTFDGLTDPGEHLALRLGSPGDVPLVRVHSECLTG
CCCCCCHHEEEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEEHHHHCC
DVFGSQRCDCGPQLHEAFRRVDAVGGYVLYLRQEGRGIGLYPKLDAYALQDAGLDTYEAN
CCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCEECCCCCCCCEEHHCCCCCEEECE
VALGYGEDERDYSVAAQMLTALGVSRVALLSNNPDKAEQLALDGITVAARVPTAVHRSEA
EEEECCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHCCEEEEECCCHHHHHCCC
NARYLAAKAQHADHTLDLGA
CCEEEEECCCCCCCEEECCC
>Mature Secondary Structure 
TAAVRTELMVPLRLADGWSTLARLYTFDGLTDPGEHLALRLGSPGDVPLVRVHSECLTG
CCCCCHHEEEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEEHHHHCC
DVFGSQRCDCGPQLHEAFRRVDAVGGYVLYLRQEGRGIGLYPKLDAYALQDAGLDTYEAN
CCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCEECCCCCCCCEEHHCCCCCEEECE
VALGYGEDERDYSVAAQMLTALGVSRVALLSNNPDKAEQLALDGITVAARVPTAVHRSEA
EEEECCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHCCEEEEECCCHHHHHCCC
NARYLAAKAQHADHTLDLGA
CCEEEEECCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA