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The map label for this gene is mocR [H]

Identifier: 119715923

GI number: 119715923

Start: 1794738

End: 1796213

Strand: Direct

Name: mocR [H]

Synonym: Noca_1688

Alternate gene names: 119715923

Gene position: 1794738-1796213 (Clockwise)

Preceding gene: 119715919

Following gene: 119715927

Centisome position: 36.0

GC content: 77.44

Gene sequence:

>1476_bases
ATGGACCTGCCGGTCGACCTGGACGCGCGCGCCGACCGGGCGAGCGCGATCTATCGCGCGCTGCTCGAGGCGATCCGCGC
CGGCCGGGTCGGTGCCGGTGACCGGCTGCCGCCGACCCGCACCCTGGCCCGCGACCTGGGGGTCGCGCGCAACACGGTTG
CCACCGCGTACGAGCGGCTCGCCGCCGAGGGCCTCCTCGACGCCCGCGTGGGCGCGGGCACCTACGTCACCGACCTGGCC
GCGCCGGTGCCGGCGCCGCGCCGCCCCGGCTCGCTGCACCCACGGGCCGGCTGGTCGTTCCGGCCGCTGCCGGTGAGCGG
CGAGCAGCCGGCACCGCCGTACGACTTCCGGGTCGGCATCCCCGACGCGTCGCTGTTCCCGTTCGACACCTGGCGTCGAC
TGGTGGCCGCGGAGCTCCGCGCCGGGGCGCACCGCCCGGGCACCTACGCCCACCCAGCGGGCCTGCCGCAGCTGCGGGCC
GCCATCGTCCGCTACCTCGCCCTGGCCCGCGGCGTCGCAGCCGAGGCCGACGACGTCGTGGTGACCCACGGCACCCAGCA
GGCCCTCGACCTGGTCGCCCGGGTGCTGCTCGAGCCAGGCGACGTCGTCGCGGTCGAGGACCCCGGCTACCCGTTCGCGC
GCGAGCTGTTCGCGTCGCACGGCGCCCGCGTGGTGCCCGTCCCGGTCGACGCGGAGGGCCTGGTCGTCGAGCGGGTCCCG
GAGCGGGCCCGGCTGGTGTTCAGCACCCCCTCACACCAGTTCCCGCTCGGTCCGCCGCTCTCGCTGGCCCGGCGCCAGGC
GCTGCTCGAGCTCGCCAACCGACACCGGGTCGCGATCGTCGAGGACGACTACGACAGCGAGTTCCGGTTCACCGATCGCC
CGCTCGAGACGCTGCACGCGATGGACCGGCACGGCCGGGTCGTCTACGTCGGCACCTTCTCGAAGTCGCTGCTCCCGGCC
CTGCGGGCGGGCTACCTGGTCGCTCCCGAGCCGCTGCGCGAGGCGCTGCTCGGGGCCCGCCAGCTGGCGGACGGCCACGG
CGGTCCGGCCGAGCAGGCCGCGCTCGCCCACTTCGTGGCCGACGGGCTCCTCGCCCGGCACCTCAGGCGGGCTCGGGCGA
CGTACGCCGAGCGTCGCGAGCTGGTCCGGTCCGGGCTGGAGCGGCTGCTCGCGGACCGCCTCGAGGTGGTCCCGTCGGCA
GCCGGCCTGCACGTCGCCGCCACGTTCCGCGACGCCGAGGTCGACGACGCGGCGGTCGCGGAGGCGGCGCTGGCGGCCGG
CGTCGCGGTCGAGCCGCTCTCGGCGTACGCCGTCGGGCCGGACGTCCCGCCGGGCCTGGTGCTCGGCTACGGCGCCGCAG
GCACCGCCACGATCAGGCCGGGTCTGGAGCGGCTCGCCCGGCTCGTCGCGTCCACGCCATCCAGGCCACCGCGGCCGCGC
CGACCAGGAGCTGCGGCAGCAGGTAGCGCCCGGTGA

Upstream 100 bases:

>100_bases
AGCAGCCCGGTCGCGACCGCCGCCACGGCCGCCGTCAGCGCGAGCGGACGCAGGCTCCGGGAGCGCGGAGGCCGGGGGTG
CACCGCCCTAGTGTGTCGCC

Downstream 100 bases:

>100_bases
GGCCGAGCAGCACCAGCGTCGAGGCGAACGCGACGCCGGCGCCGCGACGGACCCAGGTGCCGGGCGGGAGCAGTCGGATC
GCGGCGGCGGTGCCGACCAC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MDLPVDLDARADRASAIYRALLEAIRAGRVGAGDRLPPTRTLARDLGVARNTVATAYERLAAEGLLDARVGAGTYVTDLA
APVPAPRRPGSLHPRAGWSFRPLPVSGEQPAPPYDFRVGIPDASLFPFDTWRRLVAAELRAGAHRPGTYAHPAGLPQLRA
AIVRYLALARGVAAEADDVVVTHGTQQALDLVARVLLEPGDVVAVEDPGYPFARELFASHGARVVPVPVDAEGLVVERVP
ERARLVFSTPSHQFPLGPPLSLARRQALLELANRHRVAIVEDDYDSEFRFTDRPLETLHAMDRHGRVVYVGTFSKSLLPA
LRAGYLVAPEPLREALLGARQLADGHGGPAEQAALAHFVADGLLARHLRRARATYAERRELVRSGLERLLADRLEVVPSA
AGLHVAATFRDAEVDDAAVAEAALAAGVAVEPLSAYAVGPDVPPGLVLGYGAAGTATIRPGLERLARLVASTPSRPPRPR
RPGAAAAGSAR

Sequences:

>Translated_491_residues
MDLPVDLDARADRASAIYRALLEAIRAGRVGAGDRLPPTRTLARDLGVARNTVATAYERLAAEGLLDARVGAGTYVTDLA
APVPAPRRPGSLHPRAGWSFRPLPVSGEQPAPPYDFRVGIPDASLFPFDTWRRLVAAELRAGAHRPGTYAHPAGLPQLRA
AIVRYLALARGVAAEADDVVVTHGTQQALDLVARVLLEPGDVVAVEDPGYPFARELFASHGARVVPVPVDAEGLVVERVP
ERARLVFSTPSHQFPLGPPLSLARRQALLELANRHRVAIVEDDYDSEFRFTDRPLETLHAMDRHGRVVYVGTFSKSLLPA
LRAGYLVAPEPLREALLGARQLADGHGGPAEQAALAHFVADGLLARHLRRARATYAERRELVRSGLERLLADRLEVVPSA
AGLHVAATFRDAEVDDAAVAEAALAAGVAVEPLSAYAVGPDVPPGLVLGYGAAGTATIRPGLERLARLVASTPSRPPRPR
RPGAAAAGSAR
>Mature_491_residues
MDLPVDLDARADRASAIYRALLEAIRAGRVGAGDRLPPTRTLARDLGVARNTVATAYERLAAEGLLDARVGAGTYVTDLA
APVPAPRRPGSLHPRAGWSFRPLPVSGEQPAPPYDFRVGIPDASLFPFDTWRRLVAAELRAGAHRPGTYAHPAGLPQLRA
AIVRYLALARGVAAEADDVVVTHGTQQALDLVARVLLEPGDVVAVEDPGYPFARELFASHGARVVPVPVDAEGLVVERVP
ERARLVFSTPSHQFPLGPPLSLARRQALLELANRHRVAIVEDDYDSEFRFTDRPLETLHAMDRHGRVVYVGTFSKSLLPA
LRAGYLVAPEPLREALLGARQLADGHGGPAEQAALAHFVADGLLARHLRRARATYAERRELVRSGLERLLADRLEVVPSA
AGLHVAATFRDAEVDDAAVAEAALAAGVAVEPLSAYAVGPDVPPGLVLGYGAAGTATIRPGLERLARLVASTPSRPPRPR
RPGAAAAGSAR

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=389, Percent_Identity=23.9074550128535, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI33469970, Length=389, Percent_Identity=23.9074550128535, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1790797, Length=476, Percent_Identity=28.1512605042017, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1787710, Length=434, Percent_Identity=28.5714285714286, Blast_Score=132, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6321236, Length=306, Percent_Identity=23.202614379085, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52232; Mature: 52232

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLPVDLDARADRASAIYRALLEAIRAGRVGAGDRLPPTRTLARDLGVARNTVATAYERL
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAEGLLDARVGAGTYVTDLAAPVPAPRRPGSLHPRAGWSFRPLPVSGEQPAPPYDFRVGI
HHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECC
PDASLFPFDTWRRLVAAELRAGAHRPGTYAHPAGLPQLRAAIVRYLALARGVAAEADDVV
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEE
VTHGTQQALDLVARVLLEPGDVVAVEDPGYPFARELFASHGARVVPVPVDAEGLVVERVP
EECCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCHHHCCC
ERARLVFSTPSHQFPLGPPLSLARRQALLELANRHRVAIVEDDYDSEFRFTDRPLETLHA
CHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCEECCCHHHHHHH
MDRHGRVVYVGTFSKSLLPALRAGYLVAPEPLREALLGARQLADGHGGPAEQAALAHFVA
HHHCCCEEEEECCHHHHHHHHHCCCEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
DGLLARHLRRARATYAERRELVRSGLERLLADRLEVVPSAAGLHVAATFRDAEVDDAAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHH
EAALAAGVAVEPLSAYAVGPDVPPGLVLGYGAAGTATIRPGLERLARLVASTPSRPPRPR
HHHHHHCCCCCCCHHEECCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
RPGAAAAGSAR
CCCCCCCCCCC
>Mature Secondary Structure
MDLPVDLDARADRASAIYRALLEAIRAGRVGAGDRLPPTRTLARDLGVARNTVATAYERL
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAEGLLDARVGAGTYVTDLAAPVPAPRRPGSLHPRAGWSFRPLPVSGEQPAPPYDFRVGI
HHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECC
PDASLFPFDTWRRLVAAELRAGAHRPGTYAHPAGLPQLRAAIVRYLALARGVAAEADDVV
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEE
VTHGTQQALDLVARVLLEPGDVVAVEDPGYPFARELFASHGARVVPVPVDAEGLVVERVP
EECCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCHHHCCC
ERARLVFSTPSHQFPLGPPLSLARRQALLELANRHRVAIVEDDYDSEFRFTDRPLETLHA
CHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCEECCCHHHHHHH
MDRHGRVVYVGTFSKSLLPALRAGYLVAPEPLREALLGARQLADGHGGPAEQAALAHFVA
HHHCCCEEEEECCHHHHHHHHHCCCEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
DGLLARHLRRARATYAERRELVRSGLERLLADRLEVVPSAAGLHVAATFRDAEVDDAAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHH
EAALAAGVAVEPLSAYAVGPDVPPGLVLGYGAAGTATIRPGLERLARLVASTPSRPPRPR
HHHHHHCCCCCCCHHEECCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
RPGAAAAGSAR
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]