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The map label for this gene is arlS [H]

Identifier: 119715850

GI number: 119715850

Start: 1713139

End: 1714506

Strand: Direct

Name: arlS [H]

Synonym: Noca_1614

Alternate gene names: 119715850

Gene position: 1713139-1714506 (Clockwise)

Preceding gene: 119715849

Following gene: 119715855

Centisome position: 34.36

GC content: 69.15

Gene sequence:

>1368_bases
ATGAGACGACCGAGGCCCCGCGCGCGCAGCGTGCGGGTGCGCGCCACCGCCGCGGCCACGCTGGTTGTGGCGATCTTCCT
CGCCGCAGGGGCGATCGGCTTCGCTCTGCTGCAGCGGCACCAGCTGCAGACCACCGTCGTCGACGCCGCTCGCCAGCAGG
CCGAGGACCTCTCACGCCAGGTAGCCACAACGACACCGTCCGGCGCGTTGAGCACGGGTGAAGGCGACCAGTCCCTGGTC
CAGGTCATCGACGCCCGGGGGAGGGTCATCGCGTCCAGCCCGTCCGTCGACGGGGAGCAACCCATCCTGGTGATCCAGCC
CGACCTAGGGACGACCCAGACCCGCATCACCAATTCCCTGCCCATCGGTGAAGGGAACGACTTCGTCGTGGTCGCTCGGG
GCGCATCGACCCCCGACGGACCAGTCACGATCCTGGTCGCCCAGAGCTTGGAGCTGGTCAGCGAGTCGACTGCCATCATC
GTGGGACTGCTCATGGTGGGCTATCCGCTGGTCCTGGTGGCGGTGGGGGGCACCTCGTACTGGCTCGTCGGTCGAGCTCT
TGCGCCGGTCGAGCGGATCCGCAGCCGCGTGGCCACCATCCACGGCACCTCGAAGGCCACCGACCGCGTGCCCGTCCCCG
ACACGCACGACGAGATCAGCCGCCTCGCCGAGACCATGAACGCGATGCTCAGCAGGTTGGAGGCCGCCAGCGCCAGCCAG
CGGCAGTTCGTGGCCGACGCCTCGCACGAGCTGCGGAGCCCGCTGGCCACCATTCGGGCTGTCCACGAGATCGCGGTGCT
GCACCCGGACGCCCAGGACTGGGACCAGGCGAACCGCGAGGTCCTGGGGGAGCTGGACCGCGTCGACCGGCTCGTGGCCG
ACCTTGTGCTGCTCGCCCGAGCAGACGAACGCGGAATCCCGGTCACCCTCGAGGAGGTCGATCTCGACGACCTCCTCCAC
CAGGAAGCCGATCGCCTGCGACGACTGCATAGTCTGGACATCGTCCTCCACGCGCCGCCGGTGCGAGCGGTCACCGACCG
CCACCAGCTCGCTCGTGCGCTGCGCAACCTCACCGACAACGCGGCTCGCCACTGCAAGTCCCGAGTCGAGCTGCGTCTCA
GCGAAGCCAACGGATCCGCCACGATCGAGGTGACCGACGACGGCCCCGGGATCCCCCCGACCGACCGGATCCGCGTCTTC
GACCGGTTCGTACGTTTGGACCAGAGTCGCGCTCGGTCCCAGGGAGGCACGGGCCTCGGGCTATCCATCGCCCGTGAGAT
CTCCGTCTCCCTCGGGGGGGCCCTTGACCTGGTCGACAGCGAGGTCGGTGCCCGATTTTCACTGAAGATCCCACTGGCAC
CAGAGTGA

Upstream 100 bases:

>100_bases
TCTATGTCGGCTACCTGCGTCGCAAGATCGACCAGCCCTTCGGCACCACCACGATCCAGACCATGCGCGGGGCCGGCTAC
CGGCTGCTGGGTGACGGCGT

Downstream 100 bases:

>100_bases
GGTCGTCCGACACGCGGGGGGGGGGGGGGGGGGACCGCGTGCGAGGGGACCTCAGGCCCTCCCAACTCAGCTGACTTGAC
CGGACGTCCAGCGTGCGCAT

Product: ATPase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MRRPRPRARSVRVRATAAATLVVAIFLAAGAIGFALLQRHQLQTTVVDAARQQAEDLSRQVATTTPSGALSTGEGDQSLV
QVIDARGRVIASSPSVDGEQPILVIQPDLGTTQTRITNSLPIGEGNDFVVVARGASTPDGPVTILVAQSLELVSESTAII
VGLLMVGYPLVLVAVGGTSYWLVGRALAPVERIRSRVATIHGTSKATDRVPVPDTHDEISRLAETMNAMLSRLEAASASQ
RQFVADASHELRSPLATIRAVHEIAVLHPDAQDWDQANREVLGELDRVDRLVADLVLLARADERGIPVTLEEVDLDDLLH
QEADRLRRLHSLDIVLHAPPVRAVTDRHQLARALRNLTDNAARHCKSRVELRLSEANGSATIEVTDDGPGIPPTDRIRVF
DRFVRLDQSRARSQGGTGLGLSIAREISVSLGGALDLVDSEVGARFSLKIPLAPE

Sequences:

>Translated_455_residues
MRRPRPRARSVRVRATAAATLVVAIFLAAGAIGFALLQRHQLQTTVVDAARQQAEDLSRQVATTTPSGALSTGEGDQSLV
QVIDARGRVIASSPSVDGEQPILVIQPDLGTTQTRITNSLPIGEGNDFVVVARGASTPDGPVTILVAQSLELVSESTAII
VGLLMVGYPLVLVAVGGTSYWLVGRALAPVERIRSRVATIHGTSKATDRVPVPDTHDEISRLAETMNAMLSRLEAASASQ
RQFVADASHELRSPLATIRAVHEIAVLHPDAQDWDQANREVLGELDRVDRLVADLVLLARADERGIPVTLEEVDLDDLLH
QEADRLRRLHSLDIVLHAPPVRAVTDRHQLARALRNLTDNAARHCKSRVELRLSEANGSATIEVTDDGPGIPPTDRIRVF
DRFVRLDQSRARSQGGTGLGLSIAREISVSLGGALDLVDSEVGARFSLKIPLAPE
>Mature_455_residues
MRRPRPRARSVRVRATAAATLVVAIFLAAGAIGFALLQRHQLQTTVVDAARQQAEDLSRQVATTTPSGALSTGEGDQSLV
QVIDARGRVIASSPSVDGEQPILVIQPDLGTTQTRITNSLPIGEGNDFVVVARGASTPDGPVTILVAQSLELVSESTAII
VGLLMVGYPLVLVAVGGTSYWLVGRALAPVERIRSRVATIHGTSKATDRVPVPDTHDEISRLAETMNAMLSRLEAASASQ
RQFVADASHELRSPLATIRAVHEIAVLHPDAQDWDQANREVLGELDRVDRLVADLVLLARADERGIPVTLEEVDLDDLLH
QEADRLRRLHSLDIVLHAPPVRAVTDRHQLARALRNLTDNAARHCKSRVELRLSEANGSATIEVTDDGPGIPPTDRIRVF
DRFVRLDQSRARSQGGTGLGLSIAREISVSLGGALDLVDSEVGARFSLKIPLAPE

Specific function: Member of the two-component regulatory system ArlS/ArlR. ArlS probably functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to ArlR [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=260, Percent_Identity=34.2307692307692, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1788393, Length=279, Percent_Identity=31.5412186379928, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1786783, Length=338, Percent_Identity=25.7396449704142, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1790346, Length=236, Percent_Identity=30.0847457627119, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1789403, Length=356, Percent_Identity=30.3370786516854, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790861, Length=331, Percent_Identity=28.7009063444109, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786600, Length=248, Percent_Identity=29.4354838709677, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787374, Length=289, Percent_Identity=26.9896193771626, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790551, Length=283, Percent_Identity=28.9752650176678, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789808, Length=240, Percent_Identity=25.8333333333333, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786912, Length=267, Percent_Identity=29.9625468164794, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=25.7261410788382, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788279, Length=225, Percent_Identity=27.5555555555556, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082128, Length=235, Percent_Identity=30.2127659574468, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI87081816, Length=236, Percent_Identity=28.8135593220339, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48900; Mature: 48900

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRPRPRARSVRVRATAAATLVVAIFLAAGAIGFALLQRHQLQTTVVDAARQQAEDLSRQ
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VATTTPSGALSTGEGDQSLVQVIDARGRVIASSPSVDGEQPILVIQPDLGTTQTRITNSL
HHCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCEEEECCCCCCCHHHHCCCC
PIGEGNDFVVVARGASTPDGPVTILVAQSLELVSESTAIIVGLLMVGYPLVLVAVGGTSY
CCCCCCCEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCE
WLVGRALAPVERIRSRVATIHGTSKATDRVPVPDTHDEISRLAETMNAMLSRLEAASASQ
EHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
RQFVADASHELRSPLATIRAVHEIAVLHPDAQDWDQANREVLGELDRVDRLVADLVLLAR
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ADERGIPVTLEEVDLDDLLHQEADRLRRLHSLDIVLHAPPVRAVTDRHQLARALRNLTDN
CCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHH
AARHCKSRVELRLSEANGSATIEVTDDGPGIPPTDRIRVFDRFVRLDQSRARSQGGTGLG
HHHHHHHHHEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
LSIAREISVSLGGALDLVDSEVGARFSLKIPLAPE
HHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCCC
>Mature Secondary Structure
MRRPRPRARSVRVRATAAATLVVAIFLAAGAIGFALLQRHQLQTTVVDAARQQAEDLSRQ
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VATTTPSGALSTGEGDQSLVQVIDARGRVIASSPSVDGEQPILVIQPDLGTTQTRITNSL
HHCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCEEEECCCCCCCHHHHCCCC
PIGEGNDFVVVARGASTPDGPVTILVAQSLELVSESTAIIVGLLMVGYPLVLVAVGGTSY
CCCCCCCEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCE
WLVGRALAPVERIRSRVATIHGTSKATDRVPVPDTHDEISRLAETMNAMLSRLEAASASQ
EHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
RQFVADASHELRSPLATIRAVHEIAVLHPDAQDWDQANREVLGELDRVDRLVADLVLLAR
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ADERGIPVTLEEVDLDDLLHQEADRLRRLHSLDIVLHAPPVRAVTDRHQLARALRNLTDN
CCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHH
AARHCKSRVELRLSEANGSATIEVTDDGPGIPPTDRIRVFDRFVRLDQSRARSQGGTGLG
HHHHHHHHHEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
LSIAREISVSLGGALDLVDSEVGARFSLKIPLAPE
HHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA