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The map label for this gene is rstB [H]

Identifier: 119715835

GI number: 119715835

Start: 1697792

End: 1699153

Strand: Direct

Name: rstB [H]

Synonym: Noca_1599

Alternate gene names: 119715835

Gene position: 1697792-1699153 (Clockwise)

Preceding gene: 119715834

Following gene: 119715836

Centisome position: 34.05

GC content: 70.41

Gene sequence:

>1362_bases
GTGAGCCGCGTCGAGCCGGGGACGCCCCAGGGGGGCTGGGGGCGACGCGTGCTGGCCCCGGTGCGGGTGCGCGTCACTCT
TGCCGCGACCAGCGTGGCCCTGGTGGTCGGAGTCGTCGGTGCGGTGCTCTTCGTGGCATCCCTGCACCGCGACCTGGAGC
GTGCGCTGGTCGCCTCGGCCCGCCAGCAGGTGGAGACGATCACCGCGCAGCTCGAGAACGGTTCCACCCCGGCGCAGGCG
GCCGTCACGGCGCGCGACGACGTGATCACCCAGATCCTGTCACCGAGGGGCGAGATCATCGGCAGCGACCATCCGAAGAT
CTCGACGCGGCTGCGGGACTCAGCGGGGGTGTCCACCTCGGTCCAGGTGACAGGGCTCGACGACACCTATGTCGTCGTCG
CCGCTGTGGCACCTTCGGGTGAGCTGGTCACCGTTGCACACTCCCAGGAGCAACTCGCTCAGGCGAGGAGGACGGCGGAG
ACACTGTTGACCGTCGCACTGCCGCTCGGGCTCGCCCTCTTGGCGGCTGCGGTGTGGCTGGCGGTGGGACAGGCTTTGAG
GCCCGTGGAGTCGATGCGTCGGGAGGCCGCGCAGATCACCACCGCACACCAGGACCGACGACTGCCGGTGCCGCAAGGCG
GCGATGAGATCTCCCGGTTGGCGTTGACACTGAACCAGATGCTCGAGCGCATCGGTTCCTCCCAACGTGCCCAGCGCCAG
TTCGCCTCCGACGCCTCCCACGAGCTGCGCTCACCGCTGGCCGTGATCCGCCAGCTCGCCGAGGTCGCGCGCCGGCACCC
CGACCAAGCTGACGTCGTCACCTTGACGAACGAGATCCTGGCTGAGGAAGGGCGCATGGAGGAACTGGTGGCCGCGCTCC
TGACGCTGGCGAGGCTCGAGGACCGGGATCCAGCCACGAGCCACCTGGTCGATCTCGATGACGTGGTGCTCGCTGAGGTG
AAGCGTGCCCGTCCGGCCAGCGGTCCGGAGATCGATGCGACCGGCGTAGGGGCAGGGCAGGTCCGTGGCGAGGAGGTCCT
CTTCGGGCAGGTGGTCCGCAACCTGCTCAGCAACGCCCTACGCCACGCACGCTCCCGCGTCCAGGTGTCCCTCGACGAGG
TGGACAGCCGGGTGCGCCTGGTGGTCGCCGACGACGGCCCAGGCATCCCTGTCTCCGAACGCGAGCGCGTCTTCGGGCGG
TTCGTCCGCCTCGACGATGCACGCGCGCGCGACGAAGGTGGCGCAGGTCTGGGGCTCGCGATCGTCGAGAGGGTCGTCAC
CGGCCTGCAGGGGTCGGTCGCCGTGGATGAGGCCCCCGGTGGAGGAGCCAGGTTCACCGTGACGCTGCCCGCAGCCGGCT
GA

Upstream 100 bases:

>100_bases
ACGTCGGACGCCTGCGACGCAAGGTGGACAAGCCGTTCGGGTGCGCCGACCTCGAGACCTTCCGCGGGACCGGGTATCGC
CTCCGGGTTCCGGAGGTCCC

Downstream 100 bases:

>100_bases
CCTTGCTGGGTCACGCCGCACCGTCCGGCAAACGGAAGTGCCGCGTCCGCCGATCGGCGGACGCGGCACGTGCGCCCGTG
TGCGGCGGGAGGGGCTCAGC

Product: ATPase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MSRVEPGTPQGGWGRRVLAPVRVRVTLAATSVALVVGVVGAVLFVASLHRDLERALVASARQQVETITAQLENGSTPAQA
AVTARDDVITQILSPRGEIIGSDHPKISTRLRDSAGVSTSVQVTGLDDTYVVVAAVAPSGELVTVAHSQEQLAQARRTAE
TLLTVALPLGLALLAAAVWLAVGQALRPVESMRREAAQITTAHQDRRLPVPQGGDEISRLALTLNQMLERIGSSQRAQRQ
FASDASHELRSPLAVIRQLAEVARRHPDQADVVTLTNEILAEEGRMEELVAALLTLARLEDRDPATSHLVDLDDVVLAEV
KRARPASGPEIDATGVGAGQVRGEEVLFGQVVRNLLSNALRHARSRVQVSLDEVDSRVRLVVADDGPGIPVSERERVFGR
FVRLDDARARDEGGAGLGLAIVERVVTGLQGSVAVDEAPGGGARFTVTLPAAG

Sequences:

>Translated_453_residues
MSRVEPGTPQGGWGRRVLAPVRVRVTLAATSVALVVGVVGAVLFVASLHRDLERALVASARQQVETITAQLENGSTPAQA
AVTARDDVITQILSPRGEIIGSDHPKISTRLRDSAGVSTSVQVTGLDDTYVVVAAVAPSGELVTVAHSQEQLAQARRTAE
TLLTVALPLGLALLAAAVWLAVGQALRPVESMRREAAQITTAHQDRRLPVPQGGDEISRLALTLNQMLERIGSSQRAQRQ
FASDASHELRSPLAVIRQLAEVARRHPDQADVVTLTNEILAEEGRMEELVAALLTLARLEDRDPATSHLVDLDDVVLAEV
KRARPASGPEIDATGVGAGQVRGEEVLFGQVVRNLLSNALRHARSRVQVSLDEVDSRVRLVVADDGPGIPVSERERVFGR
FVRLDDARARDEGGAGLGLAIVERVVTGLQGSVAVDEAPGGGARFTVTLPAAG
>Mature_452_residues
SRVEPGTPQGGWGRRVLAPVRVRVTLAATSVALVVGVVGAVLFVASLHRDLERALVASARQQVETITAQLENGSTPAQAA
VTARDDVITQILSPRGEIIGSDHPKISTRLRDSAGVSTSVQVTGLDDTYVVVAAVAPSGELVTVAHSQEQLAQARRTAET
LLTVALPLGLALLAAAVWLAVGQALRPVESMRREAAQITTAHQDRRLPVPQGGDEISRLALTLNQMLERIGSSQRAQRQF
ASDASHELRSPLAVIRQLAEVARRHPDQADVVTLTNEILAEEGRMEELVAALLTLARLEDRDPATSHLVDLDDVVLAEVK
RARPASGPEIDATGVGAGQVRGEEVLFGQVVRNLLSNALRHARSRVQVSLDEVDSRVRLVVADDGPGIPVSERERVFGRF
VRLDDARARDEGGAGLGLAIVERVVTGLQGSVAVDEAPGGGARFTVTLPAAG

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=340, Percent_Identity=32.6470588235294, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786783, Length=290, Percent_Identity=32.7586206896552, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1788393, Length=251, Percent_Identity=34.2629482071713, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790346, Length=270, Percent_Identity=26.2962962962963, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1790861, Length=296, Percent_Identity=32.7702702702703, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787374, Length=292, Percent_Identity=26.3698630136986, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=32.5991189427313, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790551, Length=261, Percent_Identity=31.4176245210728, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788713, Length=239, Percent_Identity=25.5230125523013, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789808, Length=287, Percent_Identity=27.8745644599303, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI145693157, Length=118, Percent_Identity=36.4406779661017, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=29.4820717131474, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789403, Length=341, Percent_Identity=29.3255131964809, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788549, Length=212, Percent_Identity=26.8867924528302, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082128, Length=239, Percent_Identity=26.7782426778243, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI48994928, Length=236, Percent_Identity=26.6949152542373, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48000; Mature: 47869

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVEPGTPQGGWGRRVLAPVRVRVTLAATSVALVVGVVGAVLFVASLHRDLERALVASA
CCCCCCCCCCCCCCCCEECCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQQVETITAQLENGSTPAQAAVTARDDVITQILSPRGEIIGSDHPKISTRLRDSAGVSTS
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCE
VQVTGLDDTYVVVAAVAPSGELVTVAHSQEQLAQARRTAETLLTVALPLGLALLAAAVWL
EEEEECCCCEEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGQALRPVESMRREAAQITTAHQDRRLPVPQGGDEISRLALTLNQMLERIGSSQRAQRQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
FASDASHELRSPLAVIRQLAEVARRHPDQADVVTLTNEILAEEGRMEELVAALLTLARLE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
DRDPATSHLVDLDDVVLAEVKRARPASGPEIDATGVGAGQVRGEEVLFGQVVRNLLSNAL
CCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RHARSRVQVSLDEVDSRVRLVVADDGPGIPVSERERVFGRFVRLDDARARDEGGAGLGLA
HHHHHHHEEEHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHH
IVERVVTGLQGSVAVDEAPGGGARFTVTLPAAG
HHHHHHHCCCCCEEEECCCCCCCEEEEEECCCC
>Mature Secondary Structure 
SRVEPGTPQGGWGRRVLAPVRVRVTLAATSVALVVGVVGAVLFVASLHRDLERALVASA
CCCCCCCCCCCCCCCEECCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQQVETITAQLENGSTPAQAAVTARDDVITQILSPRGEIIGSDHPKISTRLRDSAGVSTS
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCE
VQVTGLDDTYVVVAAVAPSGELVTVAHSQEQLAQARRTAETLLTVALPLGLALLAAAVWL
EEEEECCCCEEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGQALRPVESMRREAAQITTAHQDRRLPVPQGGDEISRLALTLNQMLERIGSSQRAQRQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
FASDASHELRSPLAVIRQLAEVARRHPDQADVVTLTNEILAEEGRMEELVAALLTLARLE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
DRDPATSHLVDLDDVVLAEVKRARPASGPEIDATGVGAGQVRGEEVLFGQVVRNLLSNAL
CCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RHARSRVQVSLDEVDSRVRLVVADDGPGIPVSERERVFGRFVRLDDARARDEGGAGLGLA
HHHHHHHEEEHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHH
IVERVVTGLQGSVAVDEAPGGGARFTVTLPAAG
HHHHHHHCCCCCEEEECCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]