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The map label for this gene is tcrA [H]

Identifier: 119715834

GI number: 119715834

Start: 1697115

End: 1697795

Strand: Direct

Name: tcrA [H]

Synonym: Noca_1598

Alternate gene names: 119715834

Gene position: 1697115-1697795 (Clockwise)

Preceding gene: 119715828

Following gene: 119715835

Centisome position: 34.04

GC content: 65.64

Gene sequence:

>681_bases
GTGAGGGTGCTGGTCGTCGAGGATGAGGCCAGGTTGGCCGCCTCGCTCAAGGCGGGGCTGGAGGCCGAGGGCTTCGCCGT
CGACGTAGCCGCGGACGGCGGAGAGGCGCTCTGGTATGCCGAGGAGACCAGCTACGACGTGATCCTGCTCGACGTCATGC
TGCCGGTGCTTAACGGCTACGAGGTCTGCCGGCGTCTCCGCGAGCGGGAGGTCTGGACGCCCATCCTCATGCTCACCGCT
CGAGACGAGGAGCTCGACGAGATCGAGGGTCTCGACCAGGGCGCTGATGACTATGTCACCAAGCCGTTCAGCTTCGACAT
CCTGTTAGCTCGGATCAGGTCGCTGGTGCGTCGTGGGGCCACAGAACGTCCGACCATCCTCGAGGTAGGCGATCTGCGTT
ACGACCCTGCCCGCAAGGCGGTGTCGCGGGCGGGCCAGCCCATCGACCTGACCTCGCGCGAGCTTGCGTTGATGGCCTTC
TTCATGCGCCGCGCCGGGGATGTGCTGACCAAGTTGGAGATCTTGGAGAACGTGTGGGACTTCGCCTTCGAGGGTGATCC
CAACATCGTGGAGGTTTACGTCGGACGCCTGCGACGCAAGGTGGACAAGCCGTTCGGGTGCGCCGACCTCGAGACCTTCC
GCGGGACCGGGTATCGCCTCCGGGTTCCGGAGGTCCCGTGA

Upstream 100 bases:

>100_bases
TTACCACAGGTCCACACTGTCGGGTGATCCTGTCAGCAGGCTGACAGGATCCACGGTGTTGAGTGGGATTCATCCGGGGC
AGCGGGAAAGGAGTCGGTCG

Downstream 100 bases:

>100_bases
GCCGCGTCGAGCCGGGGACGCCCCAGGGGGGCTGGGGGCGACGCGTGCTGGCCCCGGTGCGGGTGCGCGTCACTCTTGCC
GCGACCAGCGTGGCCCTGGT

Product: response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MRVLVVEDEARLAASLKAGLEAEGFAVDVAADGGEALWYAEETSYDVILLDVMLPVLNGYEVCRRLREREVWTPILMLTA
RDEELDEIEGLDQGADDYVTKPFSFDILLARIRSLVRRGATERPTILEVGDLRYDPARKAVSRAGQPIDLTSRELALMAF
FMRRAGDVLTKLEILENVWDFAFEGDPNIVEVYVGRLRRKVDKPFGCADLETFRGTGYRLRVPEVP

Sequences:

>Translated_226_residues
MRVLVVEDEARLAASLKAGLEAEGFAVDVAADGGEALWYAEETSYDVILLDVMLPVLNGYEVCRRLREREVWTPILMLTA
RDEELDEIEGLDQGADDYVTKPFSFDILLARIRSLVRRGATERPTILEVGDLRYDPARKAVSRAGQPIDLTSRELALMAF
FMRRAGDVLTKLEILENVWDFAFEGDPNIVEVYVGRLRRKVDKPFGCADLETFRGTGYRLRVPEVP
>Mature_226_residues
MRVLVVEDEARLAASLKAGLEAEGFAVDVAADGGEALWYAEETSYDVILLDVMLPVLNGYEVCRRLREREVWTPILMLTA
RDEELDEIEGLDQGADDYVTKPFSFDILLARIRSLVRRGATERPTILEVGDLRYDPARKAVSRAGQPIDLTSRELALMAF
FMRRAGDVLTKLEILENVWDFAFEGDPNIVEVYVGRLRRKVDKPFGCADLETFRGTGYRLRVPEVP

Specific function: Member of the three-protein two-component system HK1/HK2/tcrA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=43.5555555555556, Blast_Score=183, Evalue=9e-48,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=39.4495412844037, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=38.1165919282511, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=36.2385321100917, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=36.1607142857143, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=37.219730941704, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=37.0535714285714, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=36.322869955157, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=37.8854625550661, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=33.0316742081448, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=33.4801762114537, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=30.8695652173913, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=29.1304347826087, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1788550, Length=105, Percent_Identity=34.2857142857143, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=32.1739130434783, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790437, Length=110, Percent_Identity=31.8181818181818, Blast_Score=61, Evalue=8e-11,
Organism=Escherichia coli, GI48994928, Length=129, Percent_Identity=34.8837209302326, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25528; Mature: 25528

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLVVEDEARLAASLKAGLEAEGFAVDVAADGGEALWYAEETSYDVILLDVMLPVLNGY
CEEEEECCHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCCEEHHHHHHHHHCHH
EVCRRLREREVWTPILMLTARDEELDEIEGLDQGADDYVTKPFSFDILLARIRSLVRRGA
HHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCC
TERPTILEVGDLRYDPARKAVSRAGQPIDLTSRELALMAFFMRRAGDVLTKLEILENVWD
CCCCCEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAFEGDPNIVEVYVGRLRRKVDKPFGCADLETFRGTGYRLRVPEVP
HHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEECCCCC
>Mature Secondary Structure
MRVLVVEDEARLAASLKAGLEAEGFAVDVAADGGEALWYAEETSYDVILLDVMLPVLNGY
CEEEEECCHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCCEEHHHHHHHHHCHH
EVCRRLREREVWTPILMLTARDEELDEIEGLDQGADDYVTKPFSFDILLARIRSLVRRGA
HHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCC
TERPTILEVGDLRYDPARKAVSRAGQPIDLTSRELALMAFFMRRAGDVLTKLEILENVWD
CCCCCEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAFEGDPNIVEVYVGRLRRKVDKPFGCADLETFRGTGYRLRVPEVP
HHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]