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The map label for this gene is cutM [H]

Identifier: 119715725

GI number: 119715725

Start: 1576435

End: 1577277

Strand: Direct

Name: cutM [H]

Synonym: Noca_1489

Alternate gene names: 119715725

Gene position: 1576435-1577277 (Clockwise)

Preceding gene: 119715724

Following gene: 119715726

Centisome position: 31.62

GC content: 74.38

Gene sequence:

>843_bases
GTGAAGCCAGCACCGTTCGAGTACCGCCGGCCGGGGACGATCGCCGAAGCAGTGACCGCCCTGGCCGGCGGGACGGACAG
CAAGGTGCTGGCCGGTGGCCAGAGCCTGGTCCCATTGCTGTCGATGCGTCTCGCCGCCCCGGCGCTGCTCGTCGACATCA
ACGCGATCCCGGGCCTGGACACCATCGAGGTCGAGGGGGAGGACGGCGGCGTCCGGGTGGGCGCGCTCGCCCGGCATGCC
GCCGTCCTGGCCTCGCCGGACGTACACCGCGTCCAGCCCCTCGTGCCGATGGCCCTGGCCCACGTCGCGCACGCGACGAT
CCGCAACCGGGGCACCACCGTCGGCTCGCTCGTGCACGCCGACGCCGCGGCGGAGATGCCGGCGGTGCTGGCCCTGCTGG
GCGGCAGCGTCGAGGTGGAGGGCCCGGCCGGCGGGCGCACGATCCCGGCCGACGAGCTGTTCGTCGGGCCGCTGGAGTCC
TCCCTCGCCCACGACGAGATCGCGCTGTCGGCGTACTTCCCGGCGCTCGCCCCGGGCGCCGGGGTGGCGTTCGACGAGAT
CGCCCGGCGGCACGGCGACTACGCGCTGGTCGGTGCGGCGGCCCTGGTGGACGGGGACGAGGTGCGGGTCGGCTACCTCT
CGGTCGCCGACGTGCCTACCGTCGTCGACCTCTCCGGGGTTGCGGAGGAGGAGCTCGGGGACGCGGCGCTCACCCACCTC
GAGCCCGGAGACGACATCCACGCCACCGCCGAGTACCGCGCCCAGCTGGTGCGGGTGCTCACCACACGGGTGGTTCGATC
GGCACGCGAGCATGCCCAGCAGTCCAGGGAGGGACGACGGTGA

Upstream 100 bases:

>100_bases
TCGACGACGGCACGATGATCGCCGTCGGCCACGAGGGCGTGCACGCCGAGGACCACGCGGCACCGCACGACCACCACCAC
TGATCTGAGCAAAGGAAGTC

Downstream 100 bases:

>100_bases
CCGAGGAGCTGCACGACGTTCGGCTGAGCGTCAACGGCACGACGTACGACACCCGGGTGCCGGCGCGCCGGCTGCTGTCC
GACGCGCTGCGCCACGACCT

Product: carbon-monoxide dehydrogenase (acceptor)

Products: NA

Alternate protein names: CO dehydrogenase subunit M; CO-DH M [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MKPAPFEYRRPGTIAEAVTALAGGTDSKVLAGGQSLVPLLSMRLAAPALLVDINAIPGLDTIEVEGEDGGVRVGALARHA
AVLASPDVHRVQPLVPMALAHVAHATIRNRGTTVGSLVHADAAAEMPAVLALLGGSVEVEGPAGGRTIPADELFVGPLES
SLAHDEIALSAYFPALAPGAGVAFDEIARRHGDYALVGAAALVDGDEVRVGYLSVADVPTVVDLSGVAEEELGDAALTHL
EPGDDIHATAEYRAQLVRVLTTRVVRSAREHAQQSREGRR

Sequences:

>Translated_280_residues
MKPAPFEYRRPGTIAEAVTALAGGTDSKVLAGGQSLVPLLSMRLAAPALLVDINAIPGLDTIEVEGEDGGVRVGALARHA
AVLASPDVHRVQPLVPMALAHVAHATIRNRGTTVGSLVHADAAAEMPAVLALLGGSVEVEGPAGGRTIPADELFVGPLES
SLAHDEIALSAYFPALAPGAGVAFDEIARRHGDYALVGAAALVDGDEVRVGYLSVADVPTVVDLSGVAEEELGDAALTHL
EPGDDIHATAEYRAQLVRVLTTRVVRSAREHAQQSREGRR
>Mature_280_residues
MKPAPFEYRRPGTIAEAVTALAGGTDSKVLAGGQSLVPLLSMRLAAPALLVDINAIPGLDTIEVEGEDGGVRVGALARHA
AVLASPDVHRVQPLVPMALAHVAHATIRNRGTTVGSLVHADAAAEMPAVLALLGGSVEVEGPAGGRTIPADELFVGPLES
SLAHDEIALSAYFPALAPGAGVAFDEIARRHGDYALVGAAALVDGDEVRVGYLSVADVPTVVDLSGVAEEELGDAALTHL
EPGDDIHATAEYRAQLVRVLTTRVVRSAREHAQQSREGRR

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789231, Length=278, Percent_Identity=26.978417266187, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786479, Length=114, Percent_Identity=36.8421052631579, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 28912; Mature: 28912

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPAPFEYRRPGTIAEAVTALAGGTDSKVLAGGQSLVPLLSMRLAAPALLVDINAIPGLD
CCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHCCEEEEEECCCCCCC
TIEVEGEDGGVRVGALARHAAVLASPDVHRVQPLVPMALAHVAHATIRNRGTTVGSLVHA
EEEEECCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DAAAEMPAVLALLGGSVEVEGPAGGRTIPADELFVGPLESSLAHDEIALSAYFPALAPGA
HHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCC
GVAFDEIARRHGDYALVGAAALVDGDEVRVGYLSVADVPTVVDLSGVAEEELGDAALTHL
CCHHHHHHHHCCCEEEEEHHEEECCCCEEEEEEEECCCCCEEECCCCCHHHHHHHHHHCC
EPGDDIHATAEYRAQLVRVLTTRVVRSAREHAQQSREGRR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKPAPFEYRRPGTIAEAVTALAGGTDSKVLAGGQSLVPLLSMRLAAPALLVDINAIPGLD
CCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHCCEEEEEECCCCCCC
TIEVEGEDGGVRVGALARHAAVLASPDVHRVQPLVPMALAHVAHATIRNRGTTVGSLVHA
EEEEECCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DAAAEMPAVLALLGGSVEVEGPAGGRTIPADELFVGPLESSLAHDEIALSAYFPALAPGA
HHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCC
GVAFDEIARRHGDYALVGAAALVDGDEVRVGYLSVADVPTVVDLSGVAEEELGDAALTHL
CCHHHHHHHHCCCEEEEEHHEEECCCCEEEEEEEECCCCCEEECCCCCHHHHHHHHHHCC
EPGDDIHATAEYRAQLVRVLTTRVVRSAREHAQQSREGRR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]