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The map label for this gene is coxS [H]

Identifier: 119715726

GI number: 119715726

Start: 1577274

End: 1577795

Strand: Direct

Name: coxS [H]

Synonym: Noca_1490

Alternate gene names: 119715726

Gene position: 1577274-1577795 (Clockwise)

Preceding gene: 119715725

Following gene: 119715727

Centisome position: 31.63

GC content: 71.26

Gene sequence:

>522_bases
GTGACCGAGGAGCTGCACGACGTTCGGCTGAGCGTCAACGGCACGACGTACGACACCCGGGTGCCGGCGCGCCGGCTGCT
GTCCGACGCGCTGCGCCACGACCTGGGGCTCACGGGCACGCACGTGGGCTGCGAGCACGGCGTCTGCGGCGCCTGCACGA
TCCTGGTCGACGGCGAGCCGATGCGCTCCTGCCTGATGTTCGCGGTCTCAGCGGTGGACCACGAGCTCACCACGGTCGAG
GGACTGACCAACGAGGACGGGTCGCTGAGCCCCGTGCAGCAGGCGTTCTCGGAGTGCCACGGCCTCCAGTGCGGCTTCTG
CACCCCCGGCTTCCTGACCACGATCACGGCCGGGCTGCGCGACAACCCGACCCCCACGCACGAGGAGGCCCGCGACATGA
TCGCCGGCAACCTGTGCCGCTGCACCGGCTACCAGAACATCGTCAAGGCGGTGGAGCGGGCCGCCGAGCTGGTCGAGCTC
GCCGAGCTCGTCGAGACCCCCGCACCCGAAGCAGGGCGGTGA

Upstream 100 bases:

>100_bases
ACGCCACCGCCGAGTACCGCGCCCAGCTGGTGCGGGTGCTCACCACACGGGTGGTTCGATCGGCACGCGAGCATGCCCAG
CAGTCCAGGGAGGGACGACG

Downstream 100 bases:

>100_bases
TCCGATGACCACCAAGCTGATGGGCCAGAAGGTCCAGCGGGTCGAGGACCAGCGGTTCCTGCGCGGGCAGGGTCGGTACG
TCGACGACGTCGGCGTCTCC

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MTEELHDVRLSVNGTTYDTRVPARRLLSDALRHDLGLTGTHVGCEHGVCGACTILVDGEPMRSCLMFAVSAVDHELTTVE
GLTNEDGSLSPVQQAFSECHGLQCGFCTPGFLTTITAGLRDNPTPTHEEARDMIAGNLCRCTGYQNIVKAVERAAELVEL
AELVETPAPEAGR

Sequences:

>Translated_173_residues
MTEELHDVRLSVNGTTYDTRVPARRLLSDALRHDLGLTGTHVGCEHGVCGACTILVDGEPMRSCLMFAVSAVDHELTTVE
GLTNEDGSLSPVQQAFSECHGLQCGFCTPGFLTTITAGLRDNPTPTHEEARDMIAGNLCRCTGYQNIVKAVERAAELVEL
AELVETPAPEAGR
>Mature_172_residues
TEELHDVRLSVNGTTYDTRVPARRLLSDALRHDLGLTGTHVGCEHGVCGACTILVDGEPMRSCLMFAVSAVDHELTTVEG
LTNEDGSLSPVQQAFSECHGLQCGFCTPGFLTTITAGLRDNPTPTHEEARDMIAGNLCRCTGYQNIVKAVERAAELVELA
ELVETPAPEAGR

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=91, Percent_Identity=45.0549450549451, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI91823271, Length=135, Percent_Identity=40.7407407407407, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI1786480, Length=167, Percent_Identity=41.3173652694611, Blast_Score=122, Evalue=9e-30,
Organism=Escherichia coli, GI1789232, Length=147, Percent_Identity=44.8979591836735, Blast_Score=108, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17540638, Length=149, Percent_Identity=43.6241610738255, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17539860, Length=153, Percent_Identity=37.2549019607843, Blast_Score=107, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI32566215, Length=158, Percent_Identity=35.4430379746835, Blast_Score=102, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24647199, Length=155, Percent_Identity=34.8387096774194, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24647193, Length=188, Percent_Identity=30.8510638297872, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI17737937, Length=132, Percent_Identity=39.3939393939394, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24647201, Length=163, Percent_Identity=34.3558282208589, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24647197, Length=189, Percent_Identity=31.7460317460317, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24647195, Length=189, Percent_Identity=31.7460317460317, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 18553; Mature: 18422

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEELHDVRLSVNGTTYDTRVPARRLLSDALRHDLGLTGTHVGCEHGVCGACTILVDGEP
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCH
MRSCLMFAVSAVDHELTTVEGLTNEDGSLSPVQQAFSECHGLQCGFCTPGFLTTITAGLR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCC
DNPTPTHEEARDMIAGNLCRCTGYQNIVKAVERAAELVELAELVETPAPEAGR
CCCCCCHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TEELHDVRLSVNGTTYDTRVPARRLLSDALRHDLGLTGTHVGCEHGVCGACTILVDGEP
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCH
MRSCLMFAVSAVDHELTTVEGLTNEDGSLSPVQQAFSECHGLQCGFCTPGFLTTITAGLR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCC
DNPTPTHEEARDMIAGNLCRCTGYQNIVKAVERAAELVELAELVETPAPEAGR
CCCCCCHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]