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The map label for this gene is rutG [H]

Identifier: 119715724

GI number: 119715724

Start: 1574954

End: 1576417

Strand: Direct

Name: rutG [H]

Synonym: Noca_1488

Alternate gene names: 119715724

Gene position: 1574954-1576417 (Clockwise)

Preceding gene: 119715723

Following gene: 119715725

Centisome position: 31.59

GC content: 68.31

Gene sequence:

>1464_bases
ATGTCGATGTTCAAGTGGGAGTTGGTCGATCCCAAACCTGGTGAGGCCGTAGCGCCGCACCAGCGGCTCAGCTGGGGCAA
GACGGTGGGCCTCGGCGCCCAGCACGTCGTGGCGATGTTCGGGGCGACGTTCGTCTTCCCGCTGATCATGGGCCTCAATG
CCAACCTCGCCATCATGATGAGCGGCATCGCGACGATCTGCTTCCTGCTGATCGTGCAGGGCAAGGTGCCGAGCTATCTG
GGGACCTCGGCCTCGTTCGTGGGCGCCGCGGCGGCCATCTACGCCTACCAGGGCGGCGACGGGCCGGGCGGCCCCGCCGA
CGTGACGGGCGCGATCCTGGTCGCCGGCATCGTGCTGGCCATCGTCGGCGTGATCGTCCACTACCTCGGCGCCGACTCGG
TCAACGCCGTGCTGCCGCCGGTCGTCACCGGGGCCGTGGTCATGCTGATCGGCTTCAACCTGGCTCCGGTCGCGACCCTC
ACCTACATGCCCTCCGACCCGTGGGTCGCGCTGATCACGATGACTGCCGTCATCTTGATGGCGGTCGGCCTCCGCGGCTT
CTTCGGCCGGATCGCGGTGTTCCTCGGCCTGATCTTCGGCTACCTGCTCTCGGTGGTCTGGGACTGGATCTTCGGCCAGA
GCACGCTGCCGCTGCCCGGCAACCCCGAGCCCGGCCCGCACGACCGCGTCAACTGGGACGCCGTCAAGAACGCCGACTGG
TTCGGCTTCCCGGTCCACACCAAGGACGGGCTCGTCGGCAACCAGGCCTTCACCGACGGCTACGCGAACGTCGGCTGGCA
CATGCCGTCGTTCTCGATCGCGTTCATCCTGCTCGCGCTGCCGGCGGTCATCGCCCTGGTCGCCGAGAACATCGGCCACG
TCAAGGCAGTGGCGGAGATGACCAAGACCGACCTCGACCCGGTCATGGGCCGGGCGATCGCCGCCGACGGTGTCGGCACG
GTCATCGCCTCGACGGTCGGTGGCTCGCCGACCACGACGTACGCCGAGAACATCGGCGTCATGGCGGCCACCCGGGTCTA
CTCCACGGCGGCCTACTTCGTCGCCGCGATCGTGGCGATCCTGCTGGGTCTGGTGCCCAAGTTCGGTCAGATCGTCAACG
CGACCCCGCCGGCCGTGCTCGGCGGCATCACGCTCGTCCTCTACGGCATGATCGGCCTGCTCGGCGCCAAGATCTGGAAG
GAGAACGGCGTCGACTTCGCCAAGCCCATCAACCTGGTCCCGGTCGCCGCCGGCATCATCCTCGCGATCGGCAACGCCGA
CCTGAAGATCACCGACGACTTCCACCTGACCGGCATCGCGCTCGGCACTCTCGTGGTCGTCCTCGGCTATCACCTCGCGC
GGGTGGTCGCCCCCAAGGACCTCGACGACGGCACGATGATCGCCGTCGGCCACGAGGGCGTGCACGCCGAGGACCACGCG
GCACCGCACGACCACCACCACTGA

Upstream 100 bases:

>100_bases
GGCGTTCCTTCGGCATTTATCGCCGTCGTCGGTGTGTTATGTGCATCACTAGTTTGTGACCCACTCGGGACCGGTCACCA
AGGCGGAAGGGTGCTTTGTC

Downstream 100 bases:

>100_bases
TCTGAGCAAAGGAAGTCGTGAAGCCAGCACCGTTCGAGTACCGCCGGCCGGGGACGATCGCCGAAGCAGTGACCGCCCTG
GCCGGCGGGACGGACAGCAA

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MSMFKWELVDPKPGEAVAPHQRLSWGKTVGLGAQHVVAMFGATFVFPLIMGLNANLAIMMSGIATICFLLIVQGKVPSYL
GTSASFVGAAAAIYAYQGGDGPGGPADVTGAILVAGIVLAIVGVIVHYLGADSVNAVLPPVVTGAVVMLIGFNLAPVATL
TYMPSDPWVALITMTAVILMAVGLRGFFGRIAVFLGLIFGYLLSVVWDWIFGQSTLPLPGNPEPGPHDRVNWDAVKNADW
FGFPVHTKDGLVGNQAFTDGYANVGWHMPSFSIAFILLALPAVIALVAENIGHVKAVAEMTKTDLDPVMGRAIAADGVGT
VIASTVGGSPTTTYAENIGVMAATRVYSTAAYFVAAIVAILLGLVPKFGQIVNATPPAVLGGITLVLYGMIGLLGAKIWK
ENGVDFAKPINLVPVAAGIILAIGNADLKITDDFHLTGIALGTLVVVLGYHLARVVAPKDLDDGTMIAVGHEGVHAEDHA
APHDHHH

Sequences:

>Translated_487_residues
MSMFKWELVDPKPGEAVAPHQRLSWGKTVGLGAQHVVAMFGATFVFPLIMGLNANLAIMMSGIATICFLLIVQGKVPSYL
GTSASFVGAAAAIYAYQGGDGPGGPADVTGAILVAGIVLAIVGVIVHYLGADSVNAVLPPVVTGAVVMLIGFNLAPVATL
TYMPSDPWVALITMTAVILMAVGLRGFFGRIAVFLGLIFGYLLSVVWDWIFGQSTLPLPGNPEPGPHDRVNWDAVKNADW
FGFPVHTKDGLVGNQAFTDGYANVGWHMPSFSIAFILLALPAVIALVAENIGHVKAVAEMTKTDLDPVMGRAIAADGVGT
VIASTVGGSPTTTYAENIGVMAATRVYSTAAYFVAAIVAILLGLVPKFGQIVNATPPAVLGGITLVLYGMIGLLGAKIWK
ENGVDFAKPINLVPVAAGIILAIGNADLKITDDFHLTGIALGTLVVVLGYHLARVVAPKDLDDGTMIAVGHEGVHAEDHA
APHDHHH
>Mature_486_residues
SMFKWELVDPKPGEAVAPHQRLSWGKTVGLGAQHVVAMFGATFVFPLIMGLNANLAIMMSGIATICFLLIVQGKVPSYLG
TSASFVGAAAAIYAYQGGDGPGGPADVTGAILVAGIVLAIVGVIVHYLGADSVNAVLPPVVTGAVVMLIGFNLAPVATLT
YMPSDPWVALITMTAVILMAVGLRGFFGRIAVFLGLIFGYLLSVVWDWIFGQSTLPLPGNPEPGPHDRVNWDAVKNADWF
GFPVHTKDGLVGNQAFTDGYANVGWHMPSFSIAFILLALPAVIALVAENIGHVKAVAEMTKTDLDPVMGRAIAADGVGTV
IASTVGGSPTTTYAENIGVMAATRVYSTAAYFVAAIVAILLGLVPKFGQIVNATPPAVLGGITLVLYGMIGLLGAKIWKE
NGVDFAKPINLVPVAAGIILAIGNADLKITDDFHLTGIALGTLVVVLGYHLARVVAPKDLDDGTMIAVGHEGVHAEDHAA
PHDHHH

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081818, Length=461, Percent_Identity=40.1301518438178, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1788843, Length=461, Percent_Identity=31.6702819956616, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI87082181, Length=412, Percent_Identity=25.7281553398058, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17558856, Length=281, Percent_Identity=25.6227758007117, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71993493, Length=159, Percent_Identity=29.559748427673, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17542262, Length=181, Percent_Identity=28.1767955801105, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17542260, Length=202, Percent_Identity=29.7029702970297, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356175, Length=434, Percent_Identity=25.3456221198157, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 50625; Mature: 50494

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMFKWELVDPKPGEAVAPHQRLSWGKTVGLGAQHVVAMFGATFVFPLIMGLNANLAIMM
CCCEEEEECCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
SGIATICFLLIVQGKVPSYLGTSASFVGAAAAIYAYQGGDGPGGPADVTGAILVAGIVLA
HHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHH
IVGVIVHYLGADSVNAVLPPVVTGAVVMLIGFNLAPVATLTYMPSDPWVALITMTAVILM
HHHHHHHHHCCCCCCHHCCHHHHHHHHHHHCCCCCHHHEEEECCCCCHHHHHHHHHHHHH
AVGLRGFFGRIAVFLGLIFGYLLSVVWDWIFGQSTLPLPGNPEPGPHDRVNWDAVKNADW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCC
FGFPVHTKDGLVGNQAFTDGYANVGWHMPSFSIAFILLALPAVIALVAENIGHVKAVAEM
CCCCCCCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKTDLDPVMGRAIAADGVGTVIASTVGGSPTTTYAENIGVMAATRVYSTAAYFVAAIVAI
HHHCHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LLGLVPKFGQIVNATPPAVLGGITLVLYGMIGLLGAKIWKENGVDFAKPINLVPVAAGII
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHCEE
LAIGNADLKITDDFHLTGIALGTLVVVLGYHLARVVAPKDLDDGTMIAVGHEGVHAEDHA
EEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCC
APHDHHH
CCCCCCC
>Mature Secondary Structure 
SMFKWELVDPKPGEAVAPHQRLSWGKTVGLGAQHVVAMFGATFVFPLIMGLNANLAIMM
CCEEEEECCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHH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CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]