Click here to switch to the map view.

The map label for this gene is xylR [H]

Identifier: 119715538

GI number: 119715538

Start: 1375640

End: 1376842

Strand: Reverse

Name: xylR [H]

Synonym: Noca_1302

Alternate gene names: 119715538

Gene position: 1376842-1375640 (Counterclockwise)

Preceding gene: 119715543

Following gene: 119715537

Centisome position: 27.61

GC content: 74.06

Gene sequence:

>1203_bases
ATGGCTCAAGGCGGATCCCTCGGCGAGCTGCGCGCCGCCAATCTCGCCCTGGTGATCTCCACCATCGAGCAGACCGGGGC
GCTCTCCCGTGCGGACCTGATGCGGCGCACCGGCCTGTCCCGATCGACCGTGTCCAGCCTGGTCGTCCAGCTCCTCGACC
AGGGCGTGCTGGTCGAGCGTCTCGACCGCGGCACGCCGTACAAGGGCCGCAGCGGCCGGCCGCCGATCCTCCTCGAGCTC
GCGGCCCTGACCGGGGTGGTCGCCGGCATCGACGTCGGGCACCGCCACGTCCGGGTCGCCCTGGCCCGGCCGGACTCGAC
CATCGTCCTCGAACGCTCGGTGGCCCTCGATGTCGATGACTCGCCGCGCGAGTCGATGGATCGCGTGGCGACCCTGCTCG
ACGAGCTGCTCGCGGAGTCGGGCCACGAGCTCTCGGACGTGCGCGGGGCCGGCCTGGGCATTCCCGGCCCGGTGGACCGC
GGGGGCCGGATGACCTCCGGGATCCTCCCCACCTGGCGCGGGCTCCAGCCGGCCGCCGAGCTGGCGGAGCGGACCGGAGT
CATCGCCCGGGTCCACAACGACGCCCACCTCGGAGCCCGCGGGGAGCTTGCGTACGGCGCCGCGTGCGGTCACCGCGACG
TCATCTACGTCAAGGCCTCCACGGGCATCGGCGCCGGACTGATCGTCGACGGCCACCTGGTCACGGGAGCCACCGGGATC
GCCGGCGAGCTGGGCCACGTCCAGGTCGACGTGAACGGCGTGATGTGTCGCTGCGGGAGCCGCGGCTGCCTGGAGACCGA
GGTGTCCGGACCCAAGCTCGTGGAGCTGCTCCAGCCGGCGTACGACGAGCAGCTGACCGTCCCGCGCATCCTGGAGCTGG
CCCAGTCGGGCGACGCGGGCGCCACCCGGGCGCTCAACGACTTCGGCCGCCGGATCGGCCGGGTGCTCGCCAACATCGCG
AACATGCTCAACCCCGAGCAGGTCGTGGTCGGCGGCGGCTTCGGTGCCGCGCCGGCGCTGCAGGCCGGGATCCGGGACGC
GCTGGACCGATACTCCCAACCGACCACGGCCGCGGCGATCACCGTCCTCGGGGGCGCGCTCGGCGAGCGTGCCGAGGTCA
TGGGCGCGATCGCCGTCGCCCTCGACCCTCTCGAGGCCCCCCGGTCGGGCCGCCAGCACTCCCGGTCGCACGGCGCCGGG
TGA

Upstream 100 bases:

>100_bases
CGCCACGCTAAGAGCCCTATTAGTTCGGGTCAAGGATCAAAGGTAGGAAGATGCCGGAATGTTATGTCCGGATCCCGAAT
GAATCCGGTACCCTCGACGC

Downstream 100 bases:

>100_bases
CAGACTCCAGGGCATGAGCGAGTCGAAGCGTGCCCTCGTCGTGACCGACGTGCAGAACGACTTCTGCGAAGGCGGCTCAC
TGCCGGTGGCGGGCGGGGCG

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MAQGGSLGELRAANLALVISTIEQTGALSRADLMRRTGLSRSTVSSLVVQLLDQGVLVERLDRGTPYKGRSGRPPILLEL
AALTGVVAGIDVGHRHVRVALARPDSTIVLERSVALDVDDSPRESMDRVATLLDELLAESGHELSDVRGAGLGIPGPVDR
GGRMTSGILPTWRGLQPAAELAERTGVIARVHNDAHLGARGELAYGAACGHRDVIYVKASTGIGAGLIVDGHLVTGATGI
AGELGHVQVDVNGVMCRCGSRGCLETEVSGPKLVELLQPAYDEQLTVPRILELAQSGDAGATRALNDFGRRIGRVLANIA
NMLNPEQVVVGGGFGAAPALQAGIRDALDRYSQPTTAAAITVLGGALGERAEVMGAIAVALDPLEAPRSGRQHSRSHGAG

Sequences:

>Translated_400_residues
MAQGGSLGELRAANLALVISTIEQTGALSRADLMRRTGLSRSTVSSLVVQLLDQGVLVERLDRGTPYKGRSGRPPILLEL
AALTGVVAGIDVGHRHVRVALARPDSTIVLERSVALDVDDSPRESMDRVATLLDELLAESGHELSDVRGAGLGIPGPVDR
GGRMTSGILPTWRGLQPAAELAERTGVIARVHNDAHLGARGELAYGAACGHRDVIYVKASTGIGAGLIVDGHLVTGATGI
AGELGHVQVDVNGVMCRCGSRGCLETEVSGPKLVELLQPAYDEQLTVPRILELAQSGDAGATRALNDFGRRIGRVLANIA
NMLNPEQVVVGGGFGAAPALQAGIRDALDRYSQPTTAAAITVLGGALGERAEVMGAIAVALDPLEAPRSGRQHSRSHGAG
>Mature_399_residues
AQGGSLGELRAANLALVISTIEQTGALSRADLMRRTGLSRSTVSSLVVQLLDQGVLVERLDRGTPYKGRSGRPPILLELA
ALTGVVAGIDVGHRHVRVALARPDSTIVLERSVALDVDDSPRESMDRVATLLDELLAESGHELSDVRGAGLGIPGPVDRG
GRMTSGILPTWRGLQPAAELAERTGVIARVHNDAHLGARGELAYGAACGHRDVIYVKASTGIGAGLIVDGHLVTGATGIA
GELGHVQVDVNGVMCRCGSRGCLETEVSGPKLVELLQPAYDEQLTVPRILELAQSGDAGATRALNDFGRRIGRVLANIAN
MLNPEQVVVGGGFGAAPALQAGIRDALDRYSQPTTAAAITVLGGALGERAEVMGAIAVALDPLEAPRSGRQHSRSHGAG

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=310, Percent_Identity=25.1612903225806, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI298566325, Length=310, Percent_Identity=25.1612903225806, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4885285, Length=310, Percent_Identity=25.1612903225806, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI190014632, Length=310, Percent_Identity=25.1612903225806, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1787878, Length=404, Percent_Identity=28.7128712871287, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1786891, Length=362, Percent_Identity=26.5193370165746, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1787363, Length=281, Percent_Identity=28.4697508896797, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI87081733, Length=257, Percent_Identity=31.5175097276265, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI87082127, Length=213, Percent_Identity=29.5774647887324, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790522, Length=265, Percent_Identity=27.5471698113208, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 41422; Mature: 41291

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQGGSLGELRAANLALVISTIEQTGALSRADLMRRTGLSRSTVSSLVVQLLDQGVLVER
CCCCCCCCCHHHCCHHHEEEHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHH
LDRGTPYKGRSGRPPILLELAALTGVVAGIDVGHRHVRVALARPDSTIVLERSVALDVDD
HHCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEEEEEECCCC
SPRESMDRVATLLDELLAESGHELSDVRGAGLGIPGPVDRGGRMTSGILPTWRGLQPAAE
CCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
LAERTGVIARVHNDAHLGARGELAYGAACGHRDVIYVKASTGIGAGLIVDGHLVTGATGI
HHHHCCEEEEEECCCCCCCCCCEEECCCCCCCCEEEEEECCCCCCEEEEECEEEECCCCC
AGELGHVQVDVNGVMCRCGSRGCLETEVSGPKLVELLQPAYDEQLTVPRILELAQSGDAG
CCCCCEEEEECCEEEEECCCCCCEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
ATRALNDFGRRIGRVLANIANMLNPEQVVVGGGFGAAPALQAGIRDALDRYSQPTTAAAI
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHH
TVLGGALGERAEVMGAIAVALDPLEAPRSGRQHSRSHGAG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure 
AQGGSLGELRAANLALVISTIEQTGALSRADLMRRTGLSRSTVSSLVVQLLDQGVLVER
CCCCCCCCHHHCCHHHEEEHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHH
LDRGTPYKGRSGRPPILLELAALTGVVAGIDVGHRHVRVALARPDSTIVLERSVALDVDD
HHCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEEEEEECCCC
SPRESMDRVATLLDELLAESGHELSDVRGAGLGIPGPVDRGGRMTSGILPTWRGLQPAAE
CCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
LAERTGVIARVHNDAHLGARGELAYGAACGHRDVIYVKASTGIGAGLIVDGHLVTGATGI
HHHHCCEEEEEECCCCCCCCCCEEECCCCCCCCEEEEEECCCCCCEEEEECEEEECCCCC
AGELGHVQVDVNGVMCRCGSRGCLETEVSGPKLVELLQPAYDEQLTVPRILELAQSGDAG
CCCCCEEEEECCEEEEECCCCCCEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
ATRALNDFGRRIGRVLANIANMLNPEQVVVGGGFGAAPALQAGIRDALDRYSQPTTAAAI
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHH
TVLGGALGERAEVMGAIAVALDPLEAPRSGRQHSRSHGAG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]