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The map label for this gene is paaG [H]

Identifier: 119715536

GI number: 119715536

Start: 1374279

End: 1375049

Strand: Reverse

Name: paaG [H]

Synonym: Noca_1300

Alternate gene names: 119715536

Gene position: 1375049-1374279 (Counterclockwise)

Preceding gene: 119715537

Following gene: 119715533

Centisome position: 27.58

GC content: 74.58

Gene sequence:

>771_bases
TTGCCTGACCTCGAGGTCGACACCACCGACGGGGTGCTGCGGCTGAGGTTCAACCGCCCGGAGCTGCTCAACGCGCTCAC
CGGCGAGATGGCCGACGAGCTCGCCGGCACGATCGAGGCGGCGACCGGTCGTGACGAGGTCCGGGTCGTGGTGATCACCG
GGGCAGGCTCGGCGTTCTCCGCAGGAGCGGACATCTCCGGCGCCGACGCCCACGAGCACCTCGACGTCTCGGCGCTCGAC
CGGGCGAACCGGATCGTCCGCGCGATCACGTCGTGTCCCAAGCCGGTCCTCGCCGCGGTCAACGGGATGGCTGCCGGCGT
GGGGTGCTCGACCGCCCTCGCCGCCGACCTGGTCGTCGCCGGCTCCTCCGCGACCTTCCTCCTGGCGTTCTCGCGGATCG
GCCTGATGCTCGACGGCGGTGCCTCGCTGACGGTGGCGGCCGCGATCGGCCGGACCCGTGCGATGCGGATGGCCCTGCTC
GCCGAGCCGCTGGGCGCCGCGGAGGCGCACCGGGTCGGCCTGGTCAGCCATCTGGTCCCGGACCACGAGCTCGCGTCGTA
CGTCGACGCGCTCGCCGGCCGCCTCGCCACCGGACCGCCGCTGGCCCTGGCCGCGAGCAAGAAGGCGGTCAACGCGGCGA
CCCTCGCCGGCCTGGACGCCGCCCTCGAGCGCGAGCGCACCGGCCAGACCGTCCTGCTCCGCACCGCCGACGCCGCCGAG
GGGATGCGCGCCTTCTCCGAGCATCGCCGGCCGGTGTTCCGCGGCGAGTAG

Upstream 100 bases:

>100_bases
GAGGGCTTCACGACGCGGCTCCTCGCCGACCTGTGCGCGGGCGTGGCCCCGGACACCTCGGCCGCGGCGCTCGAGGAGAT
GCGGGCCGCCGGGGTGAGCG

Downstream 100 bases:

>100_bases
CCGCGCCCTCCCCCGCCTCGCGGCGAAGGAGGGCGCGACGGTCGGCGACGCTCAGCTCACCGTGATCGGCTGGCCACCGG
AGACCAGGCGCCAGTCGACG

Product: short chain enoyl-CoA hydratase / enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MPDLEVDTTDGVLRLRFNRPELLNALTGEMADELAGTIEAATGRDEVRVVVITGAGSAFSAGADISGADAHEHLDVSALD
RANRIVRAITSCPKPVLAAVNGMAAGVGCSTALAADLVVAGSSATFLLAFSRIGLMLDGGASLTVAAAIGRTRAMRMALL
AEPLGAAEAHRVGLVSHLVPDHELASYVDALAGRLATGPPLALAASKKAVNAATLAGLDAALERERTGQTVLLRTADAAE
GMRAFSEHRRPVFRGE

Sequences:

>Translated_256_residues
MPDLEVDTTDGVLRLRFNRPELLNALTGEMADELAGTIEAATGRDEVRVVVITGAGSAFSAGADISGADAHEHLDVSALD
RANRIVRAITSCPKPVLAAVNGMAAGVGCSTALAADLVVAGSSATFLLAFSRIGLMLDGGASLTVAAAIGRTRAMRMALL
AEPLGAAEAHRVGLVSHLVPDHELASYVDALAGRLATGPPLALAASKKAVNAATLAGLDAALERERTGQTVLLRTADAAE
GMRAFSEHRRPVFRGE
>Mature_255_residues
PDLEVDTTDGVLRLRFNRPELLNALTGEMADELAGTIEAATGRDEVRVVVITGAGSAFSAGADISGADAHEHLDVSALDR
ANRIVRAITSCPKPVLAAVNGMAAGVGCSTALAADLVVAGSSATFLLAFSRIGLMLDGGASLTVAAAIGRTRAMRMALLA
EPLGAAEAHRVGLVSHLVPDHELASYVDALAGRLATGPPLALAASKKAVNAATLAGLDAALERERTGQTVLLRTADAAEG
MRAFSEHRRPVFRGE

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=254, Percent_Identity=32.6771653543307, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI45643119, Length=212, Percent_Identity=31.6037735849057, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI260275230, Length=212, Percent_Identity=31.6037735849057, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI260274832, Length=212, Percent_Identity=31.6037735849057, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI31542718, Length=251, Percent_Identity=27.0916334661355, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI25453481, Length=253, Percent_Identity=27.6679841897233, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI51538573, Length=253, Percent_Identity=27.6679841897233, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4757966, Length=248, Percent_Identity=28.2258064516129, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI51538581, Length=248, Percent_Identity=28.2258064516129, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI4757968, Length=253, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI49355787, Length=253, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4502327, Length=256, Percent_Identity=29.296875, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI70995211, Length=254, Percent_Identity=27.5590551181102, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI221136756, Length=230, Percent_Identity=26.9565217391304, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI221136753, Length=230, Percent_Identity=26.9565217391304, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI221307494, Length=224, Percent_Identity=27.6785714285714, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI37594469, Length=187, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI37594471, Length=187, Percent_Identity=29.4117647058824, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI1787660, Length=251, Percent_Identity=39.8406374501992, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1787659, Length=255, Percent_Identity=36.4705882352941, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI221142681, Length=249, Percent_Identity=32.5301204819277, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788597, Length=254, Percent_Identity=29.9212598425197, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082183, Length=258, Percent_Identity=28.2945736434109, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790281, Length=180, Percent_Identity=27.7777777777778, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25145438, Length=244, Percent_Identity=34.8360655737705, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17554946, Length=253, Percent_Identity=33.596837944664, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17536985, Length=244, Percent_Identity=29.5081967213115, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17535521, Length=217, Percent_Identity=29.9539170506912, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17549921, Length=224, Percent_Identity=29.0178571428571, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17540306, Length=251, Percent_Identity=30.6772908366534, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560910, Length=244, Percent_Identity=27.0491803278689, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17534483, Length=259, Percent_Identity=27.4131274131274, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17540714, Length=225, Percent_Identity=25.7777777777778, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI25144157, Length=194, Percent_Identity=28.8659793814433, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25144160, Length=194, Percent_Identity=28.8659793814433, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI20129971, Length=249, Percent_Identity=33.3333333333333, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24653477, Length=249, Percent_Identity=33.3333333333333, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24654903, Length=227, Percent_Identity=28.6343612334802, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24653139, Length=258, Percent_Identity=28.2945736434109, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357171, Length=257, Percent_Identity=29.5719844357977, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19922422, Length=251, Percent_Identity=22.7091633466135, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI19920382, Length=214, Percent_Identity=27.1028037383178, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 26238; Mature: 26107

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDLEVDTTDGVLRLRFNRPELLNALTGEMADELAGTIEAATGRDEVRVVVITGAGSAFS
CCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCC
AGADISGADAHEHLDVSALDRANRIVRAITSCPKPVLAAVNGMAAGVGCSTALAADLVVA
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHEE
GSSATFLLAFSRIGLMLDGGASLTVAAAIGRTRAMRMALLAEPLGAAEAHRVGLVSHLVP
CCCHHHHHHHHHHCEEECCCCCEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
DHELASYVDALAGRLATGPPLALAASKKAVNAATLAGLDAALERERTGQTVLLRTADAAE
CHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHH
GMRAFSEHRRPVFRGE
HHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PDLEVDTTDGVLRLRFNRPELLNALTGEMADELAGTIEAATGRDEVRVVVITGAGSAFS
CCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCC
AGADISGADAHEHLDVSALDRANRIVRAITSCPKPVLAAVNGMAAGVGCSTALAADLVVA
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHEE
GSSATFLLAFSRIGLMLDGGASLTVAAAIGRTRAMRMALLAEPLGAAEAHRVGLVSHLVP
CCCHHHHHHHHHHCEEECCCCCEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
DHELASYVDALAGRLATGPPLALAASKKAVNAATLAGLDAALERERTGQTVLLRTADAAE
CHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHH
GMRAFSEHRRPVFRGE
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]