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The map label for this gene is hepT [H]

Identifier: 119714798

GI number: 119714798

Start: 566839

End: 567843

Strand: Direct

Name: hepT [H]

Synonym: Noca_0534

Alternate gene names: 119714798

Gene position: 566839-567843 (Clockwise)

Preceding gene: 119714797

Following gene: 119714802

Centisome position: 11.37

GC content: 74.03

Gene sequence:

>1005_bases
GTGACCCCTGCTTCCTCCGGATTGGCGCTCCCCGTCACCGACGAGGCTCTCGCCTCCCGGTTGCGTGACCGCATGGCCGC
GGTCGAGGTCGCCCTGGCCGGCCACGTGGTCAGCCGCGCGGGCTTCGTCAGCGAGACCGCCAGCCACCTGATGGCGGCCG
GCGGGAAGCGGTTCCGGCCGCTGCTGGTGCTGCTGGCCGCCGAGACCGGGGAGCACCCCGACGCCGACGAGGTGATCACT
GCGGCGTGCGTCGTGGAGCTGACCCACCTGGCGTCGCTGTACCACGACGACGTGATGGACGAGGCCGAGCTGCGCCGCGG
CGCGGTCTCGGCCAACGCCCGTTGGGACAACCACGTCGCGATCCTCACCGGGGACTTCCTGTTCTCGAAGTCCTCCGAGC
TGACGGCCGAGCTCGGCCCGGACGCCGTCCGCGTCCAGGCCCGGACGTTCACCCGGCTGGTCGAGGGCCAGATCCTGGAG
ACCGTGCAGCCCGGGCCGGGCGAGGACCCGCTCGCCCACTACCTCGACGTGGTCGCCGGCAAGACCGGCTCGCTGATCGC
GACCTCGGCGCACTACGGCGCCCGGTTCGGCGGCGCCAGCCGCGAGGTCGAGGAGGCGCTGACGGCGTACGGCGAGATCG
TCGGCTCGGCGTTCCAGCTCTCCGACGACATCCTCGACATCGCCTCCGACTCCGGCGAGTCCGGGAAGACGCCCGGCACC
GACCTCCGCGAGGGCGTGCCCACGCTGCCGGTGCTGATGGCGCGGGCCTCGACCGACCCCGCGGACGCGCGCCTGCTCGA
GCTGCTCGGCGGCGACCTCACCGATGACGACCGGCACGCCGAGGCGCTGCGCCTGCTGCGGGCCCACCCGGCCCTCGGCC
AGGCCCGCGACTACGTGATCGCCCGCGCGCACGAGGCCAAGGCCCACCTCGCCGTCGTACCCCCTGGCCCGGTGCGCGAC
GCGCTCGAGGCGTTCGCCGACCTGGTGGCTGTCCGTTCCTCCTAG

Upstream 100 bases:

>100_bases
CCTCGGCGACGATCTTCGTCGGCGTGGCCGCGACCCTGGTGCTCGGTGTCGTTCCCGGACCGGTGCTCGATCTCGCCGCC
AATGCAGGACAATTCGTCAG

Downstream 100 bases:

>100_bases
CTACTGGGTCTCGACCCGCCGGTCGCGGCTTCGTTCCTCAGCCGCGCGGCTTGCTCGACCTTCGCCAGCCCACGCGCCGC
CCTCGTTCCTCGGGCGACGC

Product: trans-hexaprenyltranstransferase

Products: NA

Alternate protein names: HEPPP synthase subunit 2 [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTPASSGLALPVTDEALASRLRDRMAAVEVALAGHVVSRAGFVSETASHLMAAGGKRFRPLLVLLAAETGEHPDADEVIT
AACVVELTHLASLYHDDVMDEAELRRGAVSANARWDNHVAILTGDFLFSKSSELTAELGPDAVRVQARTFTRLVEGQILE
TVQPGPGEDPLAHYLDVVAGKTGSLIATSAHYGARFGGASREVEEALTAYGEIVGSAFQLSDDILDIASDSGESGKTPGT
DLREGVPTLPVLMARASTDPADARLLELLGGDLTDDDRHAEALRLLRAHPALGQARDYVIARAHEAKAHLAVVPPGPVRD
ALEAFADLVAVRSS

Sequences:

>Translated_334_residues
MTPASSGLALPVTDEALASRLRDRMAAVEVALAGHVVSRAGFVSETASHLMAAGGKRFRPLLVLLAAETGEHPDADEVIT
AACVVELTHLASLYHDDVMDEAELRRGAVSANARWDNHVAILTGDFLFSKSSELTAELGPDAVRVQARTFTRLVEGQILE
TVQPGPGEDPLAHYLDVVAGKTGSLIATSAHYGARFGGASREVEEALTAYGEIVGSAFQLSDDILDIASDSGESGKTPGT
DLREGVPTLPVLMARASTDPADARLLELLGGDLTDDDRHAEALRLLRAHPALGQARDYVIARAHEAKAHLAVVPPGPVRD
ALEAFADLVAVRSS
>Mature_333_residues
TPASSGLALPVTDEALASRLRDRMAAVEVALAGHVVSRAGFVSETASHLMAAGGKRFRPLLVLLAAETGEHPDADEVITA
ACVVELTHLASLYHDDVMDEAELRRGAVSANARWDNHVAILTGDFLFSKSSELTAELGPDAVRVQARTFTRLVEGQILET
VQPGPGEDPLAHYLDVVAGKTGSLIATSAHYGARFGGASREVEEALTAYGEIVGSAFQLSDDILDIASDSGESGKTPGTD
LREGVPTLPVLMARASTDPADARLLELLGGDLTDDDRHAEALRLLRAHPALGQARDYVIARAHEAKAHLAVVPPGPVRDA
LEAFADLVAVRSS

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=299, Percent_Identity=32.7759197324415, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI1789578, Length=311, Percent_Identity=31.5112540192926, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1786623, Length=280, Percent_Identity=31.7857142857143, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17505681, Length=177, Percent_Identity=36.7231638418079, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319475, Length=297, Percent_Identity=27.9461279461279, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24651612, Length=296, Percent_Identity=31.0810810810811, Blast_Score=124, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014119
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.30 [H]

Molecular weight: Translated: 35141; Mature: 35010

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPASSGLALPVTDEALASRLRDRMAAVEVALAGHVVSRAGFVSETASHLMAAGGKRFRP
CCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LLVLLAAETGEHPDADEVITAACVVELTHLASLYHDDVMDEAELRRGAVSANARWDNHVA
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCEEE
ILTGDFLFSKSSELTAELGPDAVRVQARTFTRLVEGQILETVQPGPGEDPLAHYLDVVAG
EEECCHHHCCCCCCHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
KTGSLIATSAHYGARFGGASREVEEALTAYGEIVGSAFQLSDDILDIASDSGESGKTPGT
CCCCEEEECCHHCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DLREGVPTLPVLMARASTDPADARLLELLGGDLTDDDRHAEALRLLRAHPALGQARDYVI
HHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
ARAHEAKAHLAVVPPGPVRDALEAFADLVAVRSS
EECCCCCCEEEEECCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPASSGLALPVTDEALASRLRDRMAAVEVALAGHVVSRAGFVSETASHLMAAGGKRFRP
CCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LLVLLAAETGEHPDADEVITAACVVELTHLASLYHDDVMDEAELRRGAVSANARWDNHVA
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCEEE
ILTGDFLFSKSSELTAELGPDAVRVQARTFTRLVEGQILETVQPGPGEDPLAHYLDVVAG
EEECCHHHCCCCCCHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
KTGSLIATSAHYGARFGGASREVEEALTAYGEIVGSAFQLSDDILDIASDSGESGKTPGT
CCCCEEEECCHHCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DLREGVPTLPVLMARASTDPADARLLELLGGDLTDDDRHAEALRLLRAHPALGQARDYVI
HHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
ARAHEAKAHLAVVPPGPVRDALEAFADLVAVRSS
EECCCCCCEEEEECCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7629164 [H]