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The map label for this gene is nuoN

Identifier: 119714797

GI number: 119714797

Start: 565241

End: 566842

Strand: Direct

Name: nuoN

Synonym: Noca_0533

Alternate gene names: 119714797

Gene position: 565241-566842 (Clockwise)

Preceding gene: 119714796

Following gene: 119714798

Centisome position: 11.34

GC content: 70.41

Gene sequence:

>1602_bases
ATGGACTTCATCAAGCCCACGATCGAGTACGGCGACGTCTGGCCGCTCCTCGTGGTCTTCGGCGTCGCCGCCGTCGGCGT
GCTCGTCGAGGGGTTCGTGCCCCGCGCCCAGCGCTACCTCGTGCAGGCCGCGCTGGCGATCGCCGGCGTGGTCGTCGCCC
TGGTCGGCACGATCCTCGTGGCCCGCGACCTTGACGTGCTCGGGGACGGGGCCGCCCGCGGCGCCATCGACGTCGAGGGC
ACCATCGCGGTCGACGGCCCGGCGCTGTTCATCTGGGGGATGCTGCTGGTCTTCGCGCTCGGTGGCGCGCTGCTGTTCGC
CGAGCGCCGGCTCGAGGGCGGGGTCTCGGCGTTCGCCGGCCAGGCCGCCGCGCTGCCCGGCACCGAGGCCGAGCGGCAGG
CGTCGACGCGCGGCCTGGAGCACACCGAGGTCTACCCGCTGATGATGTTCGCGCTGGGCGGCATGATGCTGTTCGCGGCC
GCGAACGACCTGCTGACGCTGTTCGTCGCCCTCGAGGTGCTCTCGCTCCCGCTGTACCTGCTCTCCGGGCTCGCCCGGCG
CCGCCGGCTGCTGAGCCAGGAGGCGGCGCTGAAGTACTTCATGCTCGGCGCCTTCTCCTCCGGGTTCTTCCTCTACGGTG
CCGCGCTCGTCTACGGCTTCTCCGGCTCGATGGGCTTCGCCGAGATCAACGAGGCGGTGCGCGACGACGTCGGCAACCAG
ACCCTGCTGCTGATCGGCATCGGCATGCTCTCGGTCGGGCTGCTGTTCAAGGTCGGCGCGGTGCCGTTCCACTCCTGGAC
GCCCGACGTCTACCAGGGCGCGCCCACCGCGGTCACCGCCTTCATGGCGGCCGGCACGAAGATCGCGGCGTTCGGCGCGA
TGCTCCGGCTGTTCTACGTCGCCTTCGGCTCCGACCGGTGGAGCTGGCAGCCGATGCTGTGGATCATCGCGATCCTCACG
ATGCTCGTGGGTGCGCTCATCGCGATCGTCCAGACCGACATGAAGCGGATGCTCGCCTACTCGTCGGTGGCCCACACCGG
CTTCCTGCTCACCGGCGTGCTCGGCGTGCAGCAGGCCTCCGAGCTGGCCGACGGCGAGGTGACCTCGCTGCAGGCGGTGC
TCTTCTACCTCGTCACCTACGGCTTCGCGGTCGTCGGCGCGTTCGCGGTCGTCACCCTGGTGCGCGACGCGGGCGGCGAG
GCCGGCCAGTTCGTGCGCTGGCGGGGGATCGGGCGCCGCTCCCCGCTGGTCGCCGGGGTGTTCGCGTTCTTCCTGCTCTC
GATGGCCGGCATCCCGCTGACCGCCGGCTTCGTCGGCAAGTGGGCGGTCTTCACGGTGGCCCTCGCCGCCGGCGCCTGGC
CCGTGGTCATCGCAGCCGTGCTGTGCAGCATCATCGCGGTGTTCTTCTACGTGCGGGTGATCCTGCTGATGTTCTTCGAG
GACGACGACGTCAGTGCCCAGGGTGAGGTCGCGAGCGTCACGAAGCCCTCGGTCCTGACCTCGGCGACGATCTTCGTCGG
CGTGGCCGCGACCCTGGTGCTCGGTGTCGTTCCCGGACCGGTGCTCGATCTCGCCGCCAATGCAGGACAATTCGTCAGGT
GA

Upstream 100 bases:

>100_bases
TCGACGTCAGCAATCCGACGGTCGACTCCCTGCTGCAACACGTCGGCGTGTCCGACGAGGCTCCGACGGTCGCTGACCAC
GCCGAGGAAGGTGCGCACTG

Downstream 100 bases:

>100_bases
CCCCTGCTTCCTCCGGATTGGCGCTCCCCGTCACCGACGAGGCTCTCGCCTCCCGGTTGCGTGACCGCATGGCCGCGGTC
GAGGTCGCCCTGGCCGGCCA

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MDFIKPTIEYGDVWPLLVVFGVAAVGVLVEGFVPRAQRYLVQAALAIAGVVVALVGTILVARDLDVLGDGAARGAIDVEG
TIAVDGPALFIWGMLLVFALGGALLFAERRLEGGVSAFAGQAAALPGTEAERQASTRGLEHTEVYPLMMFALGGMMLFAA
ANDLLTLFVALEVLSLPLYLLSGLARRRRLLSQEAALKYFMLGAFSSGFFLYGAALVYGFSGSMGFAEINEAVRDDVGNQ
TLLLIGIGMLSVGLLFKVGAVPFHSWTPDVYQGAPTAVTAFMAAGTKIAAFGAMLRLFYVAFGSDRWSWQPMLWIIAILT
MLVGALIAIVQTDMKRMLAYSSVAHTGFLLTGVLGVQQASELADGEVTSLQAVLFYLVTYGFAVVGAFAVVTLVRDAGGE
AGQFVRWRGIGRRSPLVAGVFAFFLLSMAGIPLTAGFVGKWAVFTVALAAGAWPVVIAAVLCSIIAVFFYVRVILLMFFE
DDDVSAQGEVASVTKPSVLTSATIFVGVAATLVLGVVPGPVLDLAANAGQFVR

Sequences:

>Translated_533_residues
MDFIKPTIEYGDVWPLLVVFGVAAVGVLVEGFVPRAQRYLVQAALAIAGVVVALVGTILVARDLDVLGDGAARGAIDVEG
TIAVDGPALFIWGMLLVFALGGALLFAERRLEGGVSAFAGQAAALPGTEAERQASTRGLEHTEVYPLMMFALGGMMLFAA
ANDLLTLFVALEVLSLPLYLLSGLARRRRLLSQEAALKYFMLGAFSSGFFLYGAALVYGFSGSMGFAEINEAVRDDVGNQ
TLLLIGIGMLSVGLLFKVGAVPFHSWTPDVYQGAPTAVTAFMAAGTKIAAFGAMLRLFYVAFGSDRWSWQPMLWIIAILT
MLVGALIAIVQTDMKRMLAYSSVAHTGFLLTGVLGVQQASELADGEVTSLQAVLFYLVTYGFAVVGAFAVVTLVRDAGGE
AGQFVRWRGIGRRSPLVAGVFAFFLLSMAGIPLTAGFVGKWAVFTVALAAGAWPVVIAAVLCSIIAVFFYVRVILLMFFE
DDDVSAQGEVASVTKPSVLTSATIFVGVAATLVLGVVPGPVLDLAANAGQFVR
>Mature_533_residues
MDFIKPTIEYGDVWPLLVVFGVAAVGVLVEGFVPRAQRYLVQAALAIAGVVVALVGTILVARDLDVLGDGAARGAIDVEG
TIAVDGPALFIWGMLLVFALGGALLFAERRLEGGVSAFAGQAAALPGTEAERQASTRGLEHTEVYPLMMFALGGMMLFAA
ANDLLTLFVALEVLSLPLYLLSGLARRRRLLSQEAALKYFMLGAFSSGFFLYGAALVYGFSGSMGFAEINEAVRDDVGNQ
TLLLIGIGMLSVGLLFKVGAVPFHSWTPDVYQGAPTAVTAFMAAGTKIAAFGAMLRLFYVAFGSDRWSWQPMLWIIAILT
MLVGALIAIVQTDMKRMLAYSSVAHTGFLLTGVLGVQQASELADGEVTSLQAVLFYLVTYGFAVVGAFAVVTLVRDAGGE
AGQFVRWRGIGRRSPLVAGVFAFFLLSMAGIPLTAGFVGKWAVFTVALAAGAWPVVIAAVLCSIIAVFFYVRVILLMFFE
DDDVSAQGEVASVTKPSVLTSATIFVGVAATLVLGVVPGPVLDLAANAGQFVR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family

Homologues:

Organism=Escherichia coli, GI145693160, Length=512, Percent_Identity=35.546875, Blast_Score=248, Evalue=7e-67,
Organism=Escherichia coli, GI1788831, Length=312, Percent_Identity=28.2051282051282, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788613, Length=399, Percent_Identity=26.0651629072682, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788614, Length=358, Percent_Identity=24.5810055865922, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788827, Length=286, Percent_Identity=26.5734265734266, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUON_NOCSJ (A1SE40)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_921762.1
- STRING:   A1SE40
- GeneID:   4596200
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_0533
- HOGENOM:   HBG747830
- OMA:   FESVSIM
- PhylomeDB:   A1SE40
- ProtClustDB:   PRK05777
- BioCyc:   NSP35761:NOCA_0533-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00445
- InterPro:   IPR010096
- InterPro:   IPR001750
- TIGRFAMs:   TIGR01770

Pfam domain/function: PF00361 Oxidored_q1

EC number: =1.6.99.5

Molecular weight: Translated: 56132; Mature: 56132

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x14e95108)-; HASH(0x14f92484)-; HASH(0x15ae661c)-; HASH(0x14f92658)-; HASH(0x1572c94c)-; HASH(0x1563f980)-; HASH(0x15a66bd0)-; HASH(0x140b1f6c)-; HASH(0x15ae6814)-; HASH(0x1457ff50)-; HASH(0x15ae6ca0)-; HASH(0x140b20b0)-; HASH(0x15ae6d90)-; HASH(0x14f92664)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFIKPTIEYGDVWPLLVVFGVAAVGVLVEGFVPRAQRYLVQAALAIAGVVVALVGTILV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARDLDVLGDGAARGAIDVEGTIAVDGPALFIWGMLLVFALGGALLFAERRLEGGVSAFAG
HHHHHHHCCCCCCCCEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
QAAALPGTEAERQASTRGLEHTEVYPLMMFALGGMMLFAAANDLLTLFVALEVLSLPLYL
CCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSGLARRRRLLSQEAALKYFMLGAFSSGFFLYGAALVYGFSGSMGFAEINEAVRDDVGNQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
TLLLIGIGMLSVGLLFKVGAVPFHSWTPDVYQGAPTAVTAFMAAGTKIAAFGAMLRLFYV
EEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
AFGSDRWSWQPMLWIIAILTMLVGALIAIVQTDMKRMLAYSSVAHTGFLLTGVLGVQQAS
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELADGEVTSLQAVLFYLVTYGFAVVGAFAVVTLVRDAGGEAGQFVRWRGIGRRSPLVAGV
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHH
FAFFLLSMAGIPLTAGFVGKWAVFTVALAAGAWPVVIAAVLCSIIAVFFYVRVILLMFFE
HHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DDDVSAQGEVASVTKPSVLTSATIFVGVAATLVLGVVPGPVLDLAANAGQFVR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCH
>Mature Secondary Structure
MDFIKPTIEYGDVWPLLVVFGVAAVGVLVEGFVPRAQRYLVQAALAIAGVVVALVGTILV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARDLDVLGDGAARGAIDVEGTIAVDGPALFIWGMLLVFALGGALLFAERRLEGGVSAFAG
HHHHHHHCCCCCCCCEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
QAAALPGTEAERQASTRGLEHTEVYPLMMFALGGMMLFAAANDLLTLFVALEVLSLPLYL
CCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSGLARRRRLLSQEAALKYFMLGAFSSGFFLYGAALVYGFSGSMGFAEINEAVRDDVGNQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
TLLLIGIGMLSVGLLFKVGAVPFHSWTPDVYQGAPTAVTAFMAAGTKIAAFGAMLRLFYV
EEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
AFGSDRWSWQPMLWIIAILTMLVGALIAIVQTDMKRMLAYSSVAHTGFLLTGVLGVQQAS
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELADGEVTSLQAVLFYLVTYGFAVVGAFAVVTLVRDAGGEAGQFVRWRGIGRRSPLVAGV
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHH
FAFFLLSMAGIPLTAGFVGKWAVFTVALAAGAWPVVIAAVLCSIIAVFFYVRVILLMFFE
HHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DDDVSAQGEVASVTKPSVLTSATIFVGVAATLVLGVVPGPVLDLAANAGQFVR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA