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The map label for this gene is menC [H]

Identifier: 119714773

GI number: 119714773

Start: 539330

End: 540292

Strand: Direct

Name: menC [H]

Synonym: Noca_0509

Alternate gene names: 119714773

Gene position: 539330-540292 (Clockwise)

Preceding gene: 119714772

Following gene: 119714774

Centisome position: 10.82

GC content: 76.22

Gene sequence:

>963_bases
GTGGGCATGATCGTCTGGTCGGTGCCGATGCGGACCCGGTTCCGCGGCATCACGGTCCGCGAGGGGGTGCTGCTGCGGGG
CCCCGCCGATGCCGAGCGGCCGGGTTGGGGGGAGTGGAGCCCGTTCCTCGAGTACGACGCGGCCGTCGCCGAGCCCTGGC
TGCGCTGCGCGGAGGAGGCTGCGGCGGGCGACTGGCCGGCGCCGCTGCGCGACCGGGTGCCGGTGAACGTCACCGTGCCG
GCCGTGGGACCACAGCAGGCGCACGCGATCGTGCTGGCCGGCGGCTGCCGGACGGCCAAGGTCAAGGTCGCCGAGCCCGG
CCAGACCGCGGCCGACGACCAGGCGCGGCTCGAGGCGGTCCGAGACGCGCTGGGCGCAGACGGGCGGGTGCGCATCGACG
TCAACGGCCTGTGGGACCTCGACACCGCGGTCGCCTCGATCCCCGTGCTCGACCGGGCGGCCGGTGGCCTCGAGTACGTC
GAGCAGCCCTGCGCGAGCGTCGAGGACCTGGCCGCCGTACGCCGCCGGGTCGACGTGCCCATCGCCGCCGACGAGTCGAT
CCGCCGGGCCGCGGACCCCTACCGGGTGCGCGACCTGGAGGCCGCCGACGTCGCGGTGCTCAAGGTGCAGCCGCTCGGCG
GGGTGCGGGCCTGCCTGCGGATCGCCGAGGACATCGGGCTGCCGGTCGTGGTGTCCTCGGCGCTGGAGACCAGCGTCGGG
ATCGCCGCCGGGGTCGCCTTGGCCGCCGCCCTGCCGGAGCTGCCGTACGCCTGCGGGCTCGCCACCGTGCAGCTGCTCAC
GGCCGATGTCGTCACCGAGTCACTCCTGCCGGTCGGCGGCGAGCTGCCGGTGCGCGCAGTGCAGGTCGACGAGTCGCTCG
CGCCCGCCGACCCGGACAGGGTCGCCCACTGGGAGGCGCGGCTGGCCGAGGTGCGCGCGCTGCGACAGGATCGTCCCTCG
TGA

Upstream 100 bases:

>100_bases
GGTCCTGGGCGCCGCGCCAGCTCGTCGCCCTCGACACGATCCCCCTGCTCGGCAACGGCAAGCCGGACCGGTTGGCGCTG
CGGCACGCTGCCGTCGAGGA

Downstream 100 bases:

>100_bases
CCGCCCCTGAGCCCGCCCCGGAGTCCGCCACCGCCACCGCCCGCCGGATCCTGGCGGCCCTGGTCGAGGCCGGCGTCACC
GAGATCGTGGTCGCCCCCGG

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MGMIVWSVPMRTRFRGITVREGVLLRGPADAERPGWGEWSPFLEYDAAVAEPWLRCAEEAAAGDWPAPLRDRVPVNVTVP
AVGPQQAHAIVLAGGCRTAKVKVAEPGQTAADDQARLEAVRDALGADGRVRIDVNGLWDLDTAVASIPVLDRAAGGLEYV
EQPCASVEDLAAVRRRVDVPIAADESIRRAADPYRVRDLEAADVAVLKVQPLGGVRACLRIAEDIGLPVVVSSALETSVG
IAAGVALAAALPELPYACGLATVQLLTADVVTESLLPVGGELPVRAVQVDESLAPADPDRVAHWEARLAEVRALRQDRPS

Sequences:

>Translated_320_residues
MGMIVWSVPMRTRFRGITVREGVLLRGPADAERPGWGEWSPFLEYDAAVAEPWLRCAEEAAAGDWPAPLRDRVPVNVTVP
AVGPQQAHAIVLAGGCRTAKVKVAEPGQTAADDQARLEAVRDALGADGRVRIDVNGLWDLDTAVASIPVLDRAAGGLEYV
EQPCASVEDLAAVRRRVDVPIAADESIRRAADPYRVRDLEAADVAVLKVQPLGGVRACLRIAEDIGLPVVVSSALETSVG
IAAGVALAAALPELPYACGLATVQLLTADVVTESLLPVGGELPVRAVQVDESLAPADPDRVAHWEARLAEVRALRQDRPS
>Mature_319_residues
GMIVWSVPMRTRFRGITVREGVLLRGPADAERPGWGEWSPFLEYDAAVAEPWLRCAEEAAAGDWPAPLRDRVPVNVTVPA
VGPQQAHAIVLAGGCRTAKVKVAEPGQTAADDQARLEAVRDALGADGRVRIDVNGLWDLDTAVASIPVLDRAAGGLEYVE
QPCASVEDLAAVRRRVDVPIAADESIRRAADPYRVRDLEAADVAVLKVQPLGGVRACLRIAEDIGLPVVVSSALETSVGI
AAGVALAAALPELPYACGLATVQLLTADVVTESLLPVGGELPVRAVQVDESLAPADPDRVAHWEARLAEVRALRQDRPS

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR001354
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 33888; Mature: 33757

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMIVWSVPMRTRFRGITVREGVLLRGPADAERPGWGEWSPFLEYDAAVAEPWLRCAEEA
CCEEEEECCCHHHHCCEEEECCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AAGDWPAPLRDRVPVNVTVPAVGPQQAHAIVLAGGCRTAKVKVAEPGQTAADDQARLEAV
HCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHH
RDALGADGRVRIDVNGLWDLDTAVASIPVLDRAAGGLEYVEQPCASVEDLAAVRRRVDVP
HHHHCCCCEEEEEECCCCCHHHHHHHCCHHHHHCCCHHHHHHHHCCHHHHHHHHHHCCCC
IAADESIRRAADPYRVRDLEAADVAVLKVQPLGGVRACLRIAEDIGLPVVVSSALETSVG
CCCCHHHHHCCCCCEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
IAAGVALAAALPELPYACGLATVQLLTADVVTESLLPVGGELPVRAVQVDESLAPADPDR
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHH
VAHWEARLAEVRALRQDRPS
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GMIVWSVPMRTRFRGITVREGVLLRGPADAERPGWGEWSPFLEYDAAVAEPWLRCAEEA
CEEEEECCCHHHHCCEEEECCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AAGDWPAPLRDRVPVNVTVPAVGPQQAHAIVLAGGCRTAKVKVAEPGQTAADDQARLEAV
HCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHH
RDALGADGRVRIDVNGLWDLDTAVASIPVLDRAAGGLEYVEQPCASVEDLAAVRRRVDVP
HHHHCCCCEEEEEECCCCCHHHHHHHCCHHHHHCCCHHHHHHHHCCHHHHHHHHHHCCCC
IAADESIRRAADPYRVRDLEAADVAVLKVQPLGGVRACLRIAEDIGLPVVVSSALETSVG
CCCCHHHHHCCCCCEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
IAAGVALAAALPELPYACGLATVQLLTADVVTESLLPVGGELPVRAVQVDESLAPADPDR
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHH
VAHWEARLAEVRALRQDRPS
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]