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The map label for this gene is feaR [H]

Identifier: 119387115

GI number: 119387115

Start: 1610483

End: 1611439

Strand: Direct

Name: feaR [H]

Synonym: Pden_4410

Alternate gene names: 119387115

Gene position: 1610483-1611439 (Clockwise)

Preceding gene: 119387105

Following gene: 119387118

Centisome position: 93.09

GC content: 70.85

Gene sequence:

>957_bases
ATGACCCTGGAAAGCTACAGCACCGCCGCGGCCGCACCGCCCGAACGCGCGGCGCATTGGTCGGCCATCATCGCGGATAC
CTATTTCCCGCTGCACCTGAGCTATCGCGACCCTGCCACCTTCCAGGGCCGGCTGGAGCGGCGCAGCGCCGGGCCGGTGT
CGCTGTCGCGGCTGCGCACCGAACCGGCGCGCTATGAGCGGGTGCCCGGCCTGATCCGGCAGGGCGAGGCCGAGGAATAC
CTGGTCACCATCCCCAGCCTCGCGCCGGTGCTGTTCCGCCAGTTGGGCCGCGACATCACCTGCGCCCCCGGTGGCTTCAT
CATCGAGCGCGGCGACGAGCCCTATCGCTTCGCCTATCAGGCACGCAACGACCTTCTGGTGATGAAGATCGCCCGTGGCG
CGCTGGCCGAAAGGCTGCGCCAGCCGGACCGGCTTTGCGCCACCGTCTTCGACGGGCGCGACGGCTTGGGCGGTTTGTTC
GCCGAGACGGTGCGCCGCGCCCATGCCCTGTCCGATGCGGAGGGGGCCGCCGATGTGCTGGGCCGGCACCTGATCGAGCT
GCTGGCGCTGGCGCTGGACCACCAGGCGGAAACCGACGGCGGCGCGGCCACGGTGGTCCGCGCCGCGCATCTGAAGCGCG
CGCAGGACGCGATCTTGCGCAACCTGACCGATCCCGAGCTATCGCCCGGGACGGTGGCCGCGGCCTGCGGCATCTCGAAA
CGGTATCTGCACGACCTGTTCGGCGATACCGACGCCACGGTCGCGCAATTCATCCGCGAGGCGCGGCTGAAGGCGGCACG
GGACATGTTGCAGATGCCGGGCGACCTGTCGCTGGCCGCCATCGCCTATCGCTTCGGCTTCGGCGACCAGGCGCAGTTCT
CGCGGCTGTTCCGGGCCATGTTCGGCCAGAGCCCCAGCAGCTATCGCGCCGCCTGCCGCGCGGGGCGGCAGGGCTAG

Upstream 100 bases:

>100_bases
TTGCCCCGCGGCGCAGCCGCCTGCCCCGCGCGCGAGTTTTCTTTTGCCCGATTGCTCCGGGCACGCTACGAATCGCGGAA
CCGATGCGGGGAGGCGCATC

Downstream 100 bases:

>100_bases
GGCTCAGCCCTCAAAGCGCCATTCGCCATCGCCAAGCGCCGGGGCCGCGCGTTCGGTCACCAGCGGGCTGCGCGAAAAGC
GCAACGGGCTGCGCAGCCCG

Product: helix-turn-helix domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MTLESYSTAAAAPPERAAHWSAIIADTYFPLHLSYRDPATFQGRLERRSAGPVSLSRLRTEPARYERVPGLIRQGEAEEY
LVTIPSLAPVLFRQLGRDITCAPGGFIIERGDEPYRFAYQARNDLLVMKIARGALAERLRQPDRLCATVFDGRDGLGGLF
AETVRRAHALSDAEGAADVLGRHLIELLALALDHQAETDGGAATVVRAAHLKRAQDAILRNLTDPELSPGTVAAACGISK
RYLHDLFGDTDATVAQFIREARLKAARDMLQMPGDLSLAAIAYRFGFGDQAQFSRLFRAMFGQSPSSYRAACRAGRQG

Sequences:

>Translated_318_residues
MTLESYSTAAAAPPERAAHWSAIIADTYFPLHLSYRDPATFQGRLERRSAGPVSLSRLRTEPARYERVPGLIRQGEAEEY
LVTIPSLAPVLFRQLGRDITCAPGGFIIERGDEPYRFAYQARNDLLVMKIARGALAERLRQPDRLCATVFDGRDGLGGLF
AETVRRAHALSDAEGAADVLGRHLIELLALALDHQAETDGGAATVVRAAHLKRAQDAILRNLTDPELSPGTVAAACGISK
RYLHDLFGDTDATVAQFIREARLKAARDMLQMPGDLSLAAIAYRFGFGDQAQFSRLFRAMFGQSPSSYRAACRAGRQG
>Mature_317_residues
TLESYSTAAAAPPERAAHWSAIIADTYFPLHLSYRDPATFQGRLERRSAGPVSLSRLRTEPARYERVPGLIRQGEAEEYL
VTIPSLAPVLFRQLGRDITCAPGGFIIERGDEPYRFAYQARNDLLVMKIARGALAERLRQPDRLCATVFDGRDGLGGLFA
ETVRRAHALSDAEGAADVLGRHLIELLALALDHQAETDGGAATVVRAAHLKRAQDAILRNLTDPELSPGTVAAACGISKR
YLHDLFGDTDATVAQFIREARLKAARDMLQMPGDLSLAAIAYRFGFGDQAQFSRLFRAMFGQSPSSYRAACRAGRQG

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=278, Percent_Identity=24.8201438848921, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 34758; Mature: 34627

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLESYSTAAAAPPERAAHWSAIIADTYFPLHLSYRDPATFQGRLERRSAGPVSLSRLRT
CCCCCCCCCCCCCCHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHC
EPARYERVPGLIRQGEAEEYLVTIPSLAPVLFRQLGRDITCAPGGFIIERGDEPYRFAYQ
CHHHHHHCCHHHHCCCCCCEEEECCHHHHHHHHHHCCCEEECCCCEEEECCCCCHHHHHH
ARNDLLVMKIARGALAERLRQPDRLCATVFDGRDGLGGLFAETVRRAHALSDAEGAADVL
CCCCEEEHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
GRHLIELLALALDHQAETDGGAATVVRAAHLKRAQDAILRNLTDPELSPGTVAAACGISK
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHH
RYLHDLFGDTDATVAQFIREARLKAARDMLQMPGDLSLAAIAYRFGFGDQAQFSRLFRAM
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHH
FGQSPSSYRAACRAGRQG
HCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
TLESYSTAAAAPPERAAHWSAIIADTYFPLHLSYRDPATFQGRLERRSAGPVSLSRLRT
CCCCCCCCCCCCCHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHC
EPARYERVPGLIRQGEAEEYLVTIPSLAPVLFRQLGRDITCAPGGFIIERGDEPYRFAYQ
CHHHHHHCCHHHHCCCCCCEEEECCHHHHHHHHHHCCCEEECCCCEEEECCCCCHHHHHH
ARNDLLVMKIARGALAERLRQPDRLCATVFDGRDGLGGLFAETVRRAHALSDAEGAADVL
CCCCEEEHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
GRHLIELLALALDHQAETDGGAATVVRAAHLKRAQDAILRNLTDPELSPGTVAAACGISK
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHH
RYLHDLFGDTDATVAQFIREARLKAARDMLQMPGDLSLAAIAYRFGFGDQAQFSRLFRAM
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHH
FGQSPSSYRAACRAGRQG
HCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]