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The map label for this gene is yegD [H]

Identifier: 119386960

GI number: 119386960

Start: 1420741

End: 1421979

Strand: Direct

Name: yegD [H]

Synonym: Pden_4255

Alternate gene names: 119386960

Gene position: 1420741-1421979 (Clockwise)

Preceding gene: 119386959

Following gene: 119386962

Centisome position: 82.12

GC content: 71.83

Gene sequence:

>1239_bases
ATGCGCAACGACATGCTCGCCATCGATTTCGGAACCTCGAACTCGGCCGCCGCGATCCTGCAGGACGGTCGGGTGCGGCG
CATCGCCATCGAGCCGGGAACCGAGACCCTGCCGACCGCCGTGTTCTTTCCGGCGCGCGGCGGCGCCATGCGCATCGGCA
CAGCGGCGGCCGAGGCACTGACCGAAGGGGCCGAGGGCCGCTACATGCGGGCGCTGAAAAGCGTGCTGGGCACTGCGCTT
TTCCACGAATCGCGGCTGATCGCCGGCAAGCGCCGCACGCTGGCCGAGATCGTCGCCGCCTTCCTTACCACCCTGCGCGA
GCGGGCCGAGGCGGCGACGGGCCAAGGCTTTCGCGGCGCGCTTTCCGGCCGGCCGGTGCATTTCCACTCGAACGACCCCG
GGCGCGACGCGCAGGCCCAGGCCGACCTGCGCGGCTGCTATCTGGCGGCGGGCTTCGACGAGGTCGCCTTCCTGCCCGAG
CCCGAGGCGGCGGCGCTGGCCAGCCACGGCCTTGGCCGGGCGGGCGAGATCGGGTTGATTGTCGATATCGGCGGCGGCAC
CTCGGATTTCTCGGCCTTCCGCAGCCGGGGCGACGGCTTGCAGATCCTGGCCAATCACGGCATCCGGCTGGGCGGCACGG
ATTTCGACCAGCAGGTCTCGCTGAGCCATGCCATGCCGGTGCTGGGCCATGGCGGGGAACTGCGGCGCGCGATGGGCACG
GGGCTCTTGCCGGTGCCGAATGCGATCTATGTCGATCTGGCGACCTGGGCGAAGATCCCCTTTCTGTACGTCCCCGAGAC
GCGGCGCATGGCCGCCGACATGGCCCGCATGGCGGTGGACCGCGCCGCGATGGTGCGCCTTGTCACGGTGCTGGACGAAG
AGTTGGGCCATGAGCTGGCCTTTGCCGTCGAGCGCGGCAAGATCGCCGCCAATGCCGGCGAGGGCGCACGGATCGCCATG
GGCTTCGTCGAGCCGGGGCTGGCGCCGCCGATCTCGCCCGCATCGCTGGACGCGGCGCTGTCGGGCTATCGCGCCGATCT
GCGCGAGGCCGCCGCCGAGACGCTGCGGCTGGCCGGGATCGCGCCGGCCCAGGTCGGCAGCGTGATCCTGGTCGGCGGCT
CCAGCCTGATGGGCCTGGTCGCCGAAGAGGCGCTGCGGCTTTGCCCCGGCGCGCAGCTGCGCCGCTCGGAAGCCTTTACC
GCCGTGGTGGACGGGCTGGCGCTGGCGACGGCACGCTGA

Upstream 100 bases:

>100_bases
GCTTGCCGGCGCGCGGGCGCTGGTCGGGATGCTCTGACCCCGCTTGCACCCTGCCGCGCAAAGGGCTACCAGCCCGGCCT
TTGCGGACAGGGGCACGGAA

Downstream 100 bases:

>100_bases
CGGCACCCGCCCTGCGGGGATCGGGGAACGGCCTCACCCCCGCCGTGGCCGGCCTGCCGCTCCTCAGGCGAACATCCCCC
GCACCTCGCGGGCGATGAAA

Product: molecular chaperone, DnaK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MRNDMLAIDFGTSNSAAAILQDGRVRRIAIEPGTETLPTAVFFPARGGAMRIGTAAAEALTEGAEGRYMRALKSVLGTAL
FHESRLIAGKRRTLAEIVAAFLTTLRERAEAATGQGFRGALSGRPVHFHSNDPGRDAQAQADLRGCYLAAGFDEVAFLPE
PEAAALASHGLGRAGEIGLIVDIGGGTSDFSAFRSRGDGLQILANHGIRLGGTDFDQQVSLSHAMPVLGHGGELRRAMGT
GLLPVPNAIYVDLATWAKIPFLYVPETRRMAADMARMAVDRAAMVRLVTVLDEELGHELAFAVERGKIAANAGEGARIAM
GFVEPGLAPPISPASLDAALSGYRADLREAAAETLRLAGIAPAQVGSVILVGGSSLMGLVAEEALRLCPGAQLRRSEAFT
AVVDGLALATAR

Sequences:

>Translated_412_residues
MRNDMLAIDFGTSNSAAAILQDGRVRRIAIEPGTETLPTAVFFPARGGAMRIGTAAAEALTEGAEGRYMRALKSVLGTAL
FHESRLIAGKRRTLAEIVAAFLTTLRERAEAATGQGFRGALSGRPVHFHSNDPGRDAQAQADLRGCYLAAGFDEVAFLPE
PEAAALASHGLGRAGEIGLIVDIGGGTSDFSAFRSRGDGLQILANHGIRLGGTDFDQQVSLSHAMPVLGHGGELRRAMGT
GLLPVPNAIYVDLATWAKIPFLYVPETRRMAADMARMAVDRAAMVRLVTVLDEELGHELAFAVERGKIAANAGEGARIAM
GFVEPGLAPPISPASLDAALSGYRADLREAAAETLRLAGIAPAQVGSVILVGGSSLMGLVAEEALRLCPGAQLRRSEAFT
AVVDGLALATAR
>Mature_412_residues
MRNDMLAIDFGTSNSAAAILQDGRVRRIAIEPGTETLPTAVFFPARGGAMRIGTAAAEALTEGAEGRYMRALKSVLGTAL
FHESRLIAGKRRTLAEIVAAFLTTLRERAEAATGQGFRGALSGRPVHFHSNDPGRDAQAQADLRGCYLAAGFDEVAFLPE
PEAAALASHGLGRAGEIGLIVDIGGGTSDFSAFRSRGDGLQILANHGIRLGGTDFDQQVSLSHAMPVLGHGGELRRAMGT
GLLPVPNAIYVDLATWAKIPFLYVPETRRMAADMARMAVDRAAMVRLVTVLDEELGHELAFAVERGKIAANAGEGARIAM
GFVEPGLAPPISPASLDAALSGYRADLREAAAETLRLAGIAPAQVGSVILVGGSSLMGLVAEEALRLCPGAQLRRSEAFT
AVVDGLALATAR

Specific function: Unknown

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Homo sapiens, GI16507237, Length=262, Percent_Identity=30.9160305343511, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI87082035, Length=452, Percent_Identity=26.5486725663717, Blast_Score=122, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17534015, Length=274, Percent_Identity=29.5620437956204, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17534013, Length=274, Percent_Identity=29.5620437956204, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17507981, Length=273, Percent_Identity=29.3040293040293, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24641406, Length=242, Percent_Identity=31.8181818181818, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24641408, Length=242, Percent_Identity=31.8181818181818, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24641402, Length=242, Percent_Identity=31.8181818181818, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24641404, Length=242, Percent_Identity=31.8181818181818, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 43013; Mature: 43013

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNDMLAIDFGTSNSAAAILQDGRVRRIAIEPGTETLPTAVFFPARGGAMRIGTAAAEAL
CCCCEEEEEECCCCCCCCEECCCCEEEEEECCCCCCCCCEEEEECCCCEEEEHHHHHHHH
TEGAEGRYMRALKSVLGTALFHESRLIAGKRRTLAEIVAAFLTTLRERAEAATGQGFRGA
HCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LSGRPVHFHSNDPGRDAQAQADLRGCYLAAGFDEVAFLPEPEAAALASHGLGRAGEIGLI
CCCCEEEECCCCCCCCCHHHHHHCEEEEECCCCCEEECCCCHHHHHHHCCCCCCCCEEEE
VDIGGGTSDFSAFRSRGDGLQILANHGIRLGGTDFDQQVSLSHAMPVLGHGGELRRAMGT
EECCCCCHHHHHHHHCCCCEEEEECCCEEECCCCCCHHHHHHHCCCCCCCCHHHHHHHCC
GLLPVPNAIYVDLATWAKIPFLYVPETRRMAADMARMAVDRAAMVRLVTVLDEELGHELA
CCCCCCCEEEEEHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
FAVERGKIAANAGEGARIAMGFVEPGLAPPISPASLDAALSGYRADLREAAAETLRLAGI
EEECCCCEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
APAQVGSVILVGGSSLMGLVAEEALRLCPGAQLRRSEAFTAVVDGLALATAR
CHHHHCCEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRNDMLAIDFGTSNSAAAILQDGRVRRIAIEPGTETLPTAVFFPARGGAMRIGTAAAEAL
CCCCEEEEEECCCCCCCCEECCCCEEEEEECCCCCCCCCEEEEECCCCEEEEHHHHHHHH
TEGAEGRYMRALKSVLGTALFHESRLIAGKRRTLAEIVAAFLTTLRERAEAATGQGFRGA
HCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LSGRPVHFHSNDPGRDAQAQADLRGCYLAAGFDEVAFLPEPEAAALASHGLGRAGEIGLI
CCCCEEEECCCCCCCCCHHHHHHCEEEEECCCCCEEECCCCHHHHHHHCCCCCCCCEEEE
VDIGGGTSDFSAFRSRGDGLQILANHGIRLGGTDFDQQVSLSHAMPVLGHGGELRRAMGT
EECCCCCHHHHHHHHCCCCEEEEECCCEEECCCCCCHHHHHHHCCCCCCCCHHHHHHHCC
GLLPVPNAIYVDLATWAKIPFLYVPETRRMAADMARMAVDRAAMVRLVTVLDEELGHELA
CCCCCCCEEEEEHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
FAVERGKIAANAGEGARIAMGFVEPGLAPPISPASLDAALSGYRADLREAAAETLRLAGI
EEECCCCEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
APAQVGSVILVGGSSLMGLVAEEALRLCPGAQLRRSEAFTAVVDGLALATAR
CHHHHCCEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7940673; 7984428 [H]