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The map label for this gene is cynX [H]

Identifier: 119386957

GI number: 119386957

Start: 1418104

End: 1419321

Strand: Direct

Name: cynX [H]

Synonym: Pden_4252

Alternate gene names: 119386957

Gene position: 1418104-1419321 (Clockwise)

Preceding gene: 119386956

Following gene: 119386958

Centisome position: 81.97

GC content: 73.81

Gene sequence:

>1218_bases
GTGAAGGCGAACAGGCAGCCGCTGATGCTGGCCGTGGTGGCCATGGTCGGGCTGGCGCTGCGGCCGTTCCTGACCGGGGT
CGGCCCCGTCGCGACGCCGATCTCGGCCGAAACCGGCCTTTCCATGCAGGGCCTGTCGGCCCTGACGCTGCTGCCGATCC
TGCTGATGGGGGCCGGGGCCTTTCTCGGGCCGGCGATCCAGGCGCGGCTGGGCGCGAAACGCGCCGCCGTGCTGGCGCTG
CTGGTGCTGAGCCTGGGCTCGGGCCTGCGGCTCGGGGCGCATTCGGCGCTGGACATGCTGGGCTCGGCCGTGCTGCTAGG
CGTGGGCGCGGCGGTGGTGCAGGCGGTGTTTCCCACCATCATCAAGCGCGAGTTCCCGCGCGGCATCAACCTGGCCATGG
GGCTTTACGCCGCGATGATGATGGGCGGCGGCGCCTTCGGCGCGCAGGCCGCGCCGCTGATCGCCGCCTGGTCGGGAAGC
TGGCGGCTGGCGCTTGGCTGGCTGGCCCTGCCCGCCGCACTGACCGCGCTGCTGGTCGCGCTGGCCCTGCCGCGCGAGCC
GCGCAAGCCGCAGGGCAGCGGGCAAGGACTGTGGCGCTGGCTGCGCCTGCCGCGGGTCTGGCTGCTGATGGCCTGCTTCG
GGTTGATCAACGGCGGCTATTCCTCGTCCGTCGCCTGGCTTGCGCCCGCATTCCAGGACCTGGGCTGGTCGGCGGGCGCC
AGCGGCGGGCTGCTGGCGGTGCTGGCGGTGGGACAAGCCGTCTCGGCGCTGGTCACGCCGGTCCTGGCCAGCCGCGGCAG
CGACCGGCGGCCGTGGCTGGGGATCTGCCTTGCGATGCAGGCGCTGGGCTTCGCCATGCTGGTCCTGCGCCCCGAGGCCG
CACCCTATCCCATCGCCTTCCTGCTGGGCGCCGGGCTTGGCGGCTGCTTTTCGCTGATGATGATCGTGGCGCTGGACCAC
CTGCCCGATCCGGCGCAGGCCGGGGCGCTGGCGGCGCTGATGCAGGGCGGAGGCTTCCTGCTGGCCGCGATCCCGCCCTG
GCTTCTGGCGCTGCTGCACGACCTGACCGGCAGCTTCACCCCCGGCTGGACGATGCATCTTGCCGCCGTGCTGGCGGTCT
GCGTCCTGGCGCTGCGCCTGTCGCCGGCCAGCTATCGCGGTGCCCTGCGCCAACCCGACCCGCAAGGCGCCGGCCCGGGC
GCAGCACCGGCCGAGTGA

Upstream 100 bases:

>100_bases
GGCCCCTCGACCAGCAATCCATCGCCATCCGCCACCTGCCCGTGCGGCCCGAGGGCGCCGGCGATCTTTATGCCGACTGG
AAAGCACGGCAGGAGCGGGC

Downstream 100 bases:

>100_bases
ACGATTTCGACTAGGAGGAGGAAGAACCATGCTGACCATCACCCGACTGGACCAGGCGGATGCGCGCCTGCTGATCGCCG
GCGCCGAGGCCCATGCCCGC

Product: major facilitator transporter

Products: Proton [Cytoplasm]; Cyanate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MKANRQPLMLAVVAMVGLALRPFLTGVGPVATPISAETGLSMQGLSALTLLPILLMGAGAFLGPAIQARLGAKRAAVLAL
LVLSLGSGLRLGAHSALDMLGSAVLLGVGAAVVQAVFPTIIKREFPRGINLAMGLYAAMMMGGGAFGAQAAPLIAAWSGS
WRLALGWLALPAALTALLVALALPREPRKPQGSGQGLWRWLRLPRVWLLMACFGLINGGYSSSVAWLAPAFQDLGWSAGA
SGGLLAVLAVGQAVSALVTPVLASRGSDRRPWLGICLAMQALGFAMLVLRPEAAPYPIAFLLGAGLGGCFSLMMIVALDH
LPDPAQAGALAALMQGGGFLLAAIPPWLLALLHDLTGSFTPGWTMHLAAVLAVCVLALRLSPASYRGALRQPDPQGAGPG
AAPAE

Sequences:

>Translated_405_residues
MKANRQPLMLAVVAMVGLALRPFLTGVGPVATPISAETGLSMQGLSALTLLPILLMGAGAFLGPAIQARLGAKRAAVLAL
LVLSLGSGLRLGAHSALDMLGSAVLLGVGAAVVQAVFPTIIKREFPRGINLAMGLYAAMMMGGGAFGAQAAPLIAAWSGS
WRLALGWLALPAALTALLVALALPREPRKPQGSGQGLWRWLRLPRVWLLMACFGLINGGYSSSVAWLAPAFQDLGWSAGA
SGGLLAVLAVGQAVSALVTPVLASRGSDRRPWLGICLAMQALGFAMLVLRPEAAPYPIAFLLGAGLGGCFSLMMIVALDH
LPDPAQAGALAALMQGGGFLLAAIPPWLLALLHDLTGSFTPGWTMHLAAVLAVCVLALRLSPASYRGALRQPDPQGAGPG
AAPAE
>Mature_405_residues
MKANRQPLMLAVVAMVGLALRPFLTGVGPVATPISAETGLSMQGLSALTLLPILLMGAGAFLGPAIQARLGAKRAAVLAL
LVLSLGSGLRLGAHSALDMLGSAVLLGVGAAVVQAVFPTIIKREFPRGINLAMGLYAAMMMGGGAFGAQAAPLIAAWSGS
WRLALGWLALPAALTALLVALALPREPRKPQGSGQGLWRWLRLPRVWLLMACFGLINGGYSSSVAWLAPAFQDLGWSAGA
SGGLLAVLAVGQAVSALVTPVLASRGSDRRPWLGICLAMQALGFAMLVLRPEAAPYPIAFLLGAGLGGCFSLMMIVALDH
LPDPAQAGALAALMQGGGFLLAAIPPWLLALLHDLTGSFTPGWTMHLAAVLAVCVLALRLSPASYRGALRQPDPQGAGPG
AAPAE

Specific function: This protein is part of an active transport system that transports exogenous cyanate into E.coli cells [H]

COG id: COG2807

COG function: function code P; Cyanate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Cyanate porter (TC 2.A.1.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786536, Length=377, Percent_Identity=37.4005305039788, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1788092, Length=371, Percent_Identity=25.8760107816712, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004747
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41347; Mature: 41347

Theoretical pI: Translated: 11.09; Mature: 11.09

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure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CCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; Cyanate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + Cyanate [Periplasm] = Proton [Cytoplasm] + Cyanate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3049588; 9278503 [H]