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The map label for this gene is oxlT [H]

Identifier: 119386713

GI number: 119386713

Start: 1147245

End: 1148897

Strand: Direct

Name: oxlT [H]

Synonym: Pden_4006

Alternate gene names: 119386713

Gene position: 1147245-1148897 (Clockwise)

Preceding gene: 119386710

Following gene: 119386716

Centisome position: 66.31

GC content: 65.58

Gene sequence:

>1653_bases
ATGACGGCCATAGAAGACGTTCCAGAATTCCGGACACCGTTGCTGTCTCGCGAACGCACGATAGCCCGGCCGGGCTTCAA
CCGATGGCTGGTGCCGCCTGCCGCCCTGGCGATTCACCTGTGCATCGGCATGGCCTATGGCTTCTCGGTGTTCTGGCTGC
CGCTGTCGCGCGCCATCGGGATCGCCGATCCGGTCGCCTGCGAGGGGATGAGCCTGCTTTCGGCCCTGTTCACGACCAGC
TGCGACTGGCGCATCGCCGATCTGGGCTGGATCTATACGCTGTTCTTCGTGCTGCTGGGATCCTCGGCCGCGATGTGGGG
AGGCTGGCTGGAGGTCGCAGGACCACGCAAGGCAGGCGTCGTCGCCGCCTTGTGCTGGTGCGGTGGCATGGTCGTCTCGG
GGATCGGGGTGATGACCCATCAATTGTGGCTGATGTGGATCGGCTCCGGGTTCATCGGGGGCGTCGGACTGGGCCTTGGC
TACATCTCGCCCGTCTCGACCCTGATCAAGTGGTTCCCCGACCGGCGCGGCCTGGCGACGGGCATGGCGATCATGGGCTT
TGGCGGCGGCGCGATGATCGGAGCCCCGCTGGCGGATCGGCTGATGAACCACTTCCAGTCGATGAGCGGCGTCGGCGTCT
GGCAGACCTTCTTCGTCATGGCCGCGATCTATTTCGTCTTCATGATGGCCGGCGCCTTCGGCTATCGCGTTCCGCCGGCC
GGCTGGAAGCCCGAAGGCTGGCAGCCCAAGGTTTCCGCCAGGCAGGCCGCGATGATCACCCAGCATCACGTCCATCTGCG
GGATGCGCACAAGACCCGGCAGTTCTGGCTGATCTGGCTGGTGCTTTGCCTGAACGTCTCGGCCGGGATCGGGGTGATCG
GCATGGCGTCGCCCATGCTGCAGGAGATCTTTGCCGGCCGGCTGGTCGGACGGCCGGAGTTGAGCTTTACCGAGCTGGAC
CCCAGCCAGAAGGCAGCCATCGCGGCCATTGCAGCCGGCTTCGCGGGGCTTTTGTCGCTGTTCAACATCGCGGGACGGCT
GTGCTGGGCGTCGGCCTCGGACCGGCTGGGGCGCAAGACCACCTATTTCATCTTTTTCGGCCTGGGGATCGTGCTTTACA
CCCTGGCGCCCAGTGCGGCGCATACGGGCAACCAGGTTCTGTTCGTGGCGATGATCTGCGTCATCATCTCGATGTATGGC
GGTGGATTCTCGACCGTGCCGGCCTATCTGGCGGATGTCTTCGGCACGCAGTTCGTGGGCGCGATCCATGGCAGGCTGCT
GACCGCATGGGCGACGGCGGGGATCGTCGGCCCGGTCGTGGTCAACTATCTGCGCGAGGCGCAGATCGCGGCGGGCGTGC
CACGGGCGCAGGCATACGACTACACGATGTACATCCTTGCGGGCTTTCTTGCCGTCGGCCTGATCTGCAATGCCCTGGTG
CGGCCGCTGGATGAGAAATGGTTCATGAAGCCCGAGCAGGTCGCGGCCTTGCGGGCCAGCGATGCGACGGCGGGGCAGGT
CCAGAGCGGTTCGTTCGGCATCGACCGCGGCCGGTTCGACTTGCCGGCGATGCTGGCCTGGGCTGCGGTCGGCATCCCGC
TGGCATGGGGCGTGTGGACGACGGTGATGAAGACGGCGGCATTGTTCGGGTAA

Upstream 100 bases:

>100_bases
TCGTCCGACAAGCGTCCATGTCCGGCAAAGGGCAGGGCGGCGCGGATTTCGCGACCAGCTTTGCAGGTCGCGTGCGCATC
CATTTCAGGGGAGGGGAATG

Downstream 100 bases:

>100_bases
GGTGGCGATCCCCCATCGGCGGCCATGTCGGATGCGTGGCCGCACGAGCTTCTGCCCGTCATGCGGCCGGAAGCCAGATG
CGGAAGGTGCTACCCCCGTT

Product: major facilitator transporter

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MTAIEDVPEFRTPLLSRERTIARPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSRAIGIADPVACEGMSLLSALFTTS
CDWRIADLGWIYTLFFVLLGSSAAMWGGWLEVAGPRKAGVVAALCWCGGMVVSGIGVMTHQLWLMWIGSGFIGGVGLGLG
YISPVSTLIKWFPDRRGLATGMAIMGFGGGAMIGAPLADRLMNHFQSMSGVGVWQTFFVMAAIYFVFMMAGAFGYRVPPA
GWKPEGWQPKVSARQAAMITQHHVHLRDAHKTRQFWLIWLVLCLNVSAGIGVIGMASPMLQEIFAGRLVGRPELSFTELD
PSQKAAIAAIAAGFAGLLSLFNIAGRLCWASASDRLGRKTTYFIFFGLGIVLYTLAPSAAHTGNQVLFVAMICVIISMYG
GGFSTVPAYLADVFGTQFVGAIHGRLLTAWATAGIVGPVVVNYLREAQIAAGVPRAQAYDYTMYILAGFLAVGLICNALV
RPLDEKWFMKPEQVAALRASDATAGQVQSGSFGIDRGRFDLPAMLAWAAVGIPLAWGVWTTVMKTAALFG

Sequences:

>Translated_550_residues
MTAIEDVPEFRTPLLSRERTIARPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSRAIGIADPVACEGMSLLSALFTTS
CDWRIADLGWIYTLFFVLLGSSAAMWGGWLEVAGPRKAGVVAALCWCGGMVVSGIGVMTHQLWLMWIGSGFIGGVGLGLG
YISPVSTLIKWFPDRRGLATGMAIMGFGGGAMIGAPLADRLMNHFQSMSGVGVWQTFFVMAAIYFVFMMAGAFGYRVPPA
GWKPEGWQPKVSARQAAMITQHHVHLRDAHKTRQFWLIWLVLCLNVSAGIGVIGMASPMLQEIFAGRLVGRPELSFTELD
PSQKAAIAAIAAGFAGLLSLFNIAGRLCWASASDRLGRKTTYFIFFGLGIVLYTLAPSAAHTGNQVLFVAMICVIISMYG
GGFSTVPAYLADVFGTQFVGAIHGRLLTAWATAGIVGPVVVNYLREAQIAAGVPRAQAYDYTMYILAGFLAVGLICNALV
RPLDEKWFMKPEQVAALRASDATAGQVQSGSFGIDRGRFDLPAMLAWAAVGIPLAWGVWTTVMKTAALFG
>Mature_549_residues
TAIEDVPEFRTPLLSRERTIARPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSRAIGIADPVACEGMSLLSALFTTSC
DWRIADLGWIYTLFFVLLGSSAAMWGGWLEVAGPRKAGVVAALCWCGGMVVSGIGVMTHQLWLMWIGSGFIGGVGLGLGY
ISPVSTLIKWFPDRRGLATGMAIMGFGGGAMIGAPLADRLMNHFQSMSGVGVWQTFFVMAAIYFVFMMAGAFGYRVPPAG
WKPEGWQPKVSARQAAMITQHHVHLRDAHKTRQFWLIWLVLCLNVSAGIGVIGMASPMLQEIFAGRLVGRPELSFTELDP
SQKAAIAAIAAGFAGLLSLFNIAGRLCWASASDRLGRKTTYFIFFGLGIVLYTLAPSAAHTGNQVLFVAMICVIISMYGG
GFSTVPAYLADVFGTQFVGAIHGRLLTAWATAGIVGPVVVNYLREAQIAAGVPRAQAYDYTMYILAGFLAVGLICNALVR
PLDEKWFMKPEQVAALRASDATAGQVQSGSFGIDRGRFDLPAMLAWAAVGIPLAWGVWTTVMKTAALFG

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Escherichia coli, GI1789969, Length=370, Percent_Identity=22.1621621621622, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 59075; Mature: 58944

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCC
>Mature Secondary Structure 
TAIEDVPEFRTPLLSRERTIARPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSRAIG
CCCCCCHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC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HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]