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The map label for this gene is yaeL [C]

Identifier: 119386705

GI number: 119386705

Start: 1136639

End: 1137964

Strand: Direct

Name: yaeL [C]

Synonym: Pden_3998

Alternate gene names: 119386705

Gene position: 1136639-1137964 (Clockwise)

Preceding gene: 119386704

Following gene: 119386706

Centisome position: 65.7

GC content: 71.12

Gene sequence:

>1326_bases
ATGAGCCTGGTTCTGGACATGATGGGCGGGTTCGTGTGGACCGTGGCGGCCTTCATCGTCGCGCTGTCGGTCATCGTCAC
CGTGCATGAATACGGCCATTACATCATCGGCCGGCTGTGCGGCATCAAGGCCGAGGTGTTTTCGCTGGGCTTCGGGCCGC
GGCTGGCGGCGCGGCGCGACCGGCACGGCACGGTCTGGCAGGTGGCGGCGATCCCGCTGGGCGGCTATGTGCGCTTTCTG
GGCGATGCCGATGCGGCCAGCGCGGGATCGGTGCCGGTCGATCCGGCCCGCGCGCGCCAAAGCCTGACCGGCGCGCCGCT
CTGGGCGCGCTTCGCCACCGTTGCGGCGGGGCCGGTGTTCAACTTCATCCTGTCGATCCTGGTCTTTGCCGGCATGGCGA
TCTGGCAGGGCCTGCCGGTGGACGAGGTCCGGGTGGGGCAGCTGCACCCGACGCCTCCCGGCGTCGAGATGCAGCTGCAA
CCGGGCGACCGCGTTTTGGCGCTGGACGGCCGGCCCGTCGCTAACTGGCGCGACCTTGGCGCGGCGGCGGGCGAATTGCC
CTCGCGTCCCAGCCACGACTGGACCGTGCTGCGCGACGGCACCGAAATCACCGTGCCGGGCCCCGACCCGATGCCGCCGC
TGGTCACCGGCATCGCGCCGCGCAGCCCGGCGGCCACGGCGGGGCTGAAGCCGGGCGACGTGATCCTGGCCATCGACGGC
GAGCCGGTCTCGCGCTTCGACGAATTGCGCCGGCATGTGGCCGAGGCCGAGGGCCGGCCGGTGCTGCTGAAGGTCTGGCG
CGAGGGCGAGGGCGAGGCCGACTACACCCTGGCTGCCCGCGAACAGGACCTGCCCACCGGCGACGGCTATGCAAGGCGCT
GGCTGATCGGCGTGACCGGCGGCGGCACCTATTTCGAGCCTGCGACCCGCCCGGCTGCCATGGGCGAGGCGCTGGGGATC
GGCGCCGCGCGCACCTGGGACATCATCGCCTCGTCCGTCTCGGGGCTCTGGGCGATGATCACCGGCCAGATCGGCAGCTG
CAACCTGGGCGGCGCGATCTCGATCGCCGAGACCACGGGGCAGGCGGCCTCGGCGGGGGGCGGAAACTTCATCTGGTGGA
TCGCCGTGCTGTCCGCGGCCATCGGTTTTCTGAACCTGCTGCCGGTGCCGGTGCTCGATGGCGGGCATCTGATGTTCTAT
CTCTACGAAGCGGTGGCGGGCCGGCGGCCGTCGGACCGGGTGATGGACATCCTGTCGGCGCTGGGGCTGGCGGCGGTGCT
GTCGCTGATGGTTCTGGGCCTCACCAACGATCTTTTCTGCCCCTGA

Upstream 100 bases:

>100_bases
CGCGCGAGGCCGGCTTTGCGCAAAGTCCGCGCGACCTTGGCGAAGTGCTGCATTGGGACGATTTCGCGCGGCGGGCGGCA
GCGCAATGGCAGGGGGCGGC

Downstream 100 bases:

>100_bases
GCGGCGCTAGGCTTTTGACAGTGTAGGCCGCTTCGCTGTATCCATCGGGGCAAATATGGCGGGACCAACCCGCCGGGCAA
CGCATTATTCGCGAGGGGCG

Product: putative membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MSLVLDMMGGFVWTVAAFIVALSVIVTVHEYGHYIIGRLCGIKAEVFSLGFGPRLAARRDRHGTVWQVAAIPLGGYVRFL
GDADAASAGSVPVDPARARQSLTGAPLWARFATVAAGPVFNFILSILVFAGMAIWQGLPVDEVRVGQLHPTPPGVEMQLQ
PGDRVLALDGRPVANWRDLGAAAGELPSRPSHDWTVLRDGTEITVPGPDPMPPLVTGIAPRSPAATAGLKPGDVILAIDG
EPVSRFDELRRHVAEAEGRPVLLKVWREGEGEADYTLAAREQDLPTGDGYARRWLIGVTGGGTYFEPATRPAAMGEALGI
GAARTWDIIASSVSGLWAMITGQIGSCNLGGAISIAETTGQAASAGGGNFIWWIAVLSAAIGFLNLLPVPVLDGGHLMFY
LYEAVAGRRPSDRVMDILSALGLAAVLSLMVLGLTNDLFCP

Sequences:

>Translated_441_residues
MSLVLDMMGGFVWTVAAFIVALSVIVTVHEYGHYIIGRLCGIKAEVFSLGFGPRLAARRDRHGTVWQVAAIPLGGYVRFL
GDADAASAGSVPVDPARARQSLTGAPLWARFATVAAGPVFNFILSILVFAGMAIWQGLPVDEVRVGQLHPTPPGVEMQLQ
PGDRVLALDGRPVANWRDLGAAAGELPSRPSHDWTVLRDGTEITVPGPDPMPPLVTGIAPRSPAATAGLKPGDVILAIDG
EPVSRFDELRRHVAEAEGRPVLLKVWREGEGEADYTLAAREQDLPTGDGYARRWLIGVTGGGTYFEPATRPAAMGEALGI
GAARTWDIIASSVSGLWAMITGQIGSCNLGGAISIAETTGQAASAGGGNFIWWIAVLSAAIGFLNLLPVPVLDGGHLMFY
LYEAVAGRRPSDRVMDILSALGLAAVLSLMVLGLTNDLFCP
>Mature_440_residues
SLVLDMMGGFVWTVAAFIVALSVIVTVHEYGHYIIGRLCGIKAEVFSLGFGPRLAARRDRHGTVWQVAAIPLGGYVRFLG
DADAASAGSVPVDPARARQSLTGAPLWARFATVAAGPVFNFILSILVFAGMAIWQGLPVDEVRVGQLHPTPPGVEMQLQP
GDRVLALDGRPVANWRDLGAAAGELPSRPSHDWTVLRDGTEITVPGPDPMPPLVTGIAPRSPAATAGLKPGDVILAIDGE
PVSRFDELRRHVAEAEGRPVLLKVWREGEGEADYTLAAREQDLPTGDGYARRWLIGVTGGGTYFEPATRPAAMGEALGIG
AARTWDIIASSVSGLWAMITGQIGSCNLGGAISIAETTGQAASAGGGNFIWWIAVLSAAIGFLNLLPVPVLDGGHLMFYL
YEAVAGRRPSDRVMDILSALGLAAVLSLMVLGLTNDLFCP

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=447, Percent_Identity=31.5436241610738, Blast_Score=196, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 46438; Mature: 46307

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVLDMMGGFVWTVAAFIVALSVIVTVHEYGHYIIGRLCGIKAEVFSLGFGPRLAARRD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHCCCC
RHGTVWQVAAIPLGGYVRFLGDADAASAGSVPVDPARARQSLTGAPLWARFATVAAGPVF
CCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHH
NFILSILVFAGMAIWQGLPVDEVRVGQLHPTPPGVEMQLQPGDRVLALDGRPVANWRDLG
HHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEECCCCEEEEECCCCCCCHHHHC
AAAGELPSRPSHDWTVLRDGTEITVPGPDPMPPLVTGIAPRSPAATAGLKPGDVILAIDG
CHHCCCCCCCCCCEEEEECCCEEEECCCCCCCHHHHCCCCCCCCCCCCCCCCCEEEEECC
EPVSRFDELRRHVAEAEGRPVLLKVWREGEGEADYTLAAREQDLPTGDGYARRWLIGVTG
CCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCCCCEEEEEEEEEC
GGTYFEPATRPAAMGEALGIGAARTWDIIASSVSGLWAMITGQIGSCNLGGAISIAETTG
CCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCCEEEEECCCC
QAASAGGGNFIWWIAVLSAAIGFLNLLPVPVLDGGHLMFYLYEAVAGRRPSDRVMDILSA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHCCCCHHHHHHHHHH
LGLAAVLSLMVLGLTNDLFCP
HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SLVLDMMGGFVWTVAAFIVALSVIVTVHEYGHYIIGRLCGIKAEVFSLGFGPRLAARRD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHCCCC
RHGTVWQVAAIPLGGYVRFLGDADAASAGSVPVDPARARQSLTGAPLWARFATVAAGPVF
CCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHH
NFILSILVFAGMAIWQGLPVDEVRVGQLHPTPPGVEMQLQPGDRVLALDGRPVANWRDLG
HHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEECCCCEEEEECCCCCCCHHHHC
AAAGELPSRPSHDWTVLRDGTEITVPGPDPMPPLVTGIAPRSPAATAGLKPGDVILAIDG
CHHCCCCCCCCCCEEEEECCCEEEECCCCCCCHHHHCCCCCCCCCCCCCCCCCEEEEECC
EPVSRFDELRRHVAEAEGRPVLLKVWREGEGEADYTLAAREQDLPTGDGYARRWLIGVTG
CCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCCCCEEEEEEEEEC
GGTYFEPATRPAAMGEALGIGAARTWDIIASSVSGLWAMITGQIGSCNLGGAISIAETTG
CCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCCEEEEECCCC
QAASAGGGNFIWWIAVLSAAIGFLNLLPVPVLDGGHLMFYLYEAVAGRRPSDRVMDILSA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHCCCCHHHHHHHHHH
LGLAAVLSLMVLGLTNDLFCP
HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]